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Author: Clayton Fisher
Publisher:
ISBN: 9781632416551
Category :
Languages : en
Pages : 254
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Book Description
The study of chromosomes and chromosome abnormalities is encompassed in the branch of cytogenetics. A chromosomal abnormality arises due to a structural abnormality in one or more chromosomes or due to occurrence of atypical number of chromosomes. Structural abnormalities in chromosomes can lead to deletions, duplications, inversions, insertions, translocations, etc. in chromosomes. Some of the disorders arising due to this include Jacobsen syndrome, Wolf-Hirschhorn syndrome, Charcot-Marie-Tooth disease type 1A, etc. Numerical disorders include Down syndrome, Turner syndrome, etc. Some chromosomal abnormalities are chromosomal rearrangements, aneuploidy and genomic deletion/duplication disorders. Microscopy and array comparative genomic hybridization are widely used for cytogenetic studies. This book covers in detail some existing theories and innovative concepts revolving around cytogenetics. Different approaches, evaluations, methodologies and advanced studies on cytogenetics have been included herein. The extensive content of this book provides the readers with a thorough understanding of the subject.
Author: Clayton Fisher
Publisher:
ISBN: 9781632416551
Category :
Languages : en
Pages : 254
Get Book Here
Book Description
The study of chromosomes and chromosome abnormalities is encompassed in the branch of cytogenetics. A chromosomal abnormality arises due to a structural abnormality in one or more chromosomes or due to occurrence of atypical number of chromosomes. Structural abnormalities in chromosomes can lead to deletions, duplications, inversions, insertions, translocations, etc. in chromosomes. Some of the disorders arising due to this include Jacobsen syndrome, Wolf-Hirschhorn syndrome, Charcot-Marie-Tooth disease type 1A, etc. Numerical disorders include Down syndrome, Turner syndrome, etc. Some chromosomal abnormalities are chromosomal rearrangements, aneuploidy and genomic deletion/duplication disorders. Microscopy and array comparative genomic hybridization are widely used for cytogenetic studies. This book covers in detail some existing theories and innovative concepts revolving around cytogenetics. Different approaches, evaluations, methodologies and advanced studies on cytogenetics have been included herein. The extensive content of this book provides the readers with a thorough understanding of the subject.
Author: Sverre Heim
Publisher: John Wiley & Sons
ISBN: 1118795512
Category : Medical
Languages : en
Pages : 645
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Book Description
The first three editions of this acclaimed book presented a much-needed conceptual synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations. New contributors reflecting broader international authorship and even greater expertise Greater emphasis throughout on the clinical importance and application of information about cytogenetic and molecular aberrations Includes a complete coverage of chromosome aberrations in cancer based on an assessment of the 60,000 neoplasms cytogenetically investigated to date Now produced in full color for enhanced clarity Covers how molecular genetic data (PCR-based and sequencing information) are collated with the cytogenetic data where pertinent Discusses how molecular cytogenetic data (based on studies using FISH, CGH, SNP, etc) are fused with karyotyping data to enable an as comprehensive understanding of cancer cytogenetics as is currently possible
Author: Hank Bass
Publisher: Springer Science & Business Media
ISBN: 0387708693
Category : Science
Languages : en
Pages : 346
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Book Description
This reference book provides information on plant cytogenetics for students, instructors, and researchers. Topics covered by international experts include classical cytogenetics of plant genomes; plant chromosome structure; functional, molecular cytology; and genome dynamics. In addition, chapters are included on several methods in plant cytogenetics, informatics, and even laboratory exercises for aspiring or practiced instructors. The book provides a unique combination of historical and modern subject matter, revealing the central role of plant cytogenetics in plant genetics and genomics as currently practiced. This breadth of coverage, together with the inclusion of methods and instruction, is intended to convey a deep and useful appreciation for plant cytogenetics. We hope it will inform and inspire students, researchers, and teachers to continue to employ plant cytogenetics to address fundamental questions about the cytology of plant chromosomes and genomes for years to come. Hank W. Bass is a Professor in the Department of Biological Science at Florida State University. James A. Birchler is a Professor in the Division of Biological Sciences at the University of Missouri.
Author: Marcelo L. Larramendy
Publisher: BoD – Books on Demand
ISBN: 1839689412
Category : Medical
Languages : en
Pages : 170
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Book Description
This edited book, Cytogenetics - Classical and Molecular Strategies for Analysing Heredity Material, presents recent advances in the field of cytogenetics, paying special attention to methodological achievements developed worldwide that have driven the field forward. The contributors clearly discuss several concepts and approaches useful for understanding chromosomal structure and function at its various levels, highlighting chromosomes as visible carriers of heredity material.
Author: Sverre Heim
Publisher: John Wiley & Sons
ISBN: 1118210581
Category : Medical
Languages : en
Pages : 799
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Book Description
Cancer Cytogenetics, 3rd Edition, offers a comprehensive, expanded, and up-to-date review of recent dramatic advances in this area and incorporates a vast amount of new data from the latest basic and clinical investigations. Edited by two leading experts, and now involving a new panel of international experts, the book offers an authoritative description of neoplastic processes at the chromosomal level of genomic organization. Researchers in cytogenetics, medical and molecular genetics, cellular and molecular biology, cancer research, clinical oncology, and hematology will find this reference both thorough and authoritative.
Author: Camila Blair
Publisher: American Medical Publishers
ISBN: 9781639272464
Category : Medical
Languages : en
Pages : 233
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Book Description
Molecular cytogenetics is a combination of molecular biology and cytogenetics. Molecular biology is a subset of biology that is concerned with the molecular basis of biological activity which occurs between biomolecules in numerous systems of a cell. Cytogenetics, on the other hand, is a field of genetics that deals with how the chromosomes are related to cell behavior during mitosis and meiosis. The aim of molecular cytogenetics is to distinguish between normal and cancer-causing cells using various substances. It is a useful tool for diagnosis and treatment of various malignancies like haematological malignancies, brain tumors, etc. It uses the techniques of fluorescent in situ hybridization and comparative genomic hybridization. This book unravels the recent studies in the field of molecular cytogenetics. It strives to provide a fair idea about this discipline and to help develop a better understanding of the latest advances within this field. Students, researchers, experts and all associated with molecular cytogenetics will benefit alike from this book.
Author:
Publisher:
ISBN:
Category : Cytogenetics
Languages : en
Pages : 379
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Book Description
Author: James Arthur Birchler
Publisher:
ISBN: 9783805594943
Category : Plant cytogenetics
Languages : en
Pages : 0
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Book Description
The research reported in this volume illustrates the utility of incorporating cytogenetic tools into biological studies. Somatic chromosome identification is now becoming routine in selected plant species, and the utility of this technique will increase as it expands to other taxa. Individual genes or DNA fragments can be localized to chromosomes in combination with chromosomal identification techniques, which bypasses the need for multiple generations of genetic analysis to map molecular markers to chromosomal positions. The identity of individuals with chromosomal changes can be determined in root tip metaphase spreads, with subsequent growth of these individuals for further genetic and molecular analyses. These new techniques have allowed examination of chromosomal behavior in meiotic and somatic preparations at the whole-genome level. They are also the basis for studies of changes in chromosomal structure or transposable elements in different cells of a single tissue. The studies in this volume illustrate many of these applications and the diversity of research avenues they open up. This publication will be of interest to cytogeneticists, cytologists, cell biologists and evolutionary biologists.
Author: Cesar Martins
Publisher:
ISBN: 9781612093901
Category : Cytogenetics
Languages : en
Pages : 0
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Book Description
Decades before the recent advances in molecular biology and the knowledge of the complete nucleotide sequence of several genomes, cytogenetic analysis provided the first information concerning the genome organisation. The exploration of molecular biology techniques in the cytogenetic area represents a powerful tool for advancement in the construction of physical chromosome maps of the genomes. The most important advances in cytogenetics comes from the physical anchorage of genetic linkage maps in the chromosomes through the hybridisation of DNA markers onto chromosomes. This book presents and discusses current research in the study of animal genomes under the focus of cytogenetics.
Author:
Publisher: Academic Press
ISBN: 9780123854933
Category : Science
Languages : en
Pages : 400
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Book Description
Cytometry is one of the most rapidly growing methodologies available for basic cell and molecular biology, cytogenetics, immunology, oncology, environmental sciences and also various fields of clinical medicine. This new edition, split into 2 Parts, is an almost completely new book, with nearly all of the chapters devoted to new topics. Like the previous volumes on cytometry published as part of the Methods in Cell Biology series, it provides a comprehensive description of particular cytometric methods and reviews their applications. Chapters present the theoretical foundations of the described methods, their applicability in experimental laboratory and clinical settings, and describes common traps and pitfalls such as problems with data interpretation, comparison with alternative assays, and choosing the optimal assay. Comprehensive presentation of cytometric methods covering theoretical applications, applicability, potential pitfalls, and comparisions to alternative assays Discusses many new assays developed since the previous edition Presents recent developments in cytometric intrumentation/technology
