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Author: Karl-Heinz Frömming
Publisher: Springer Science & Business Media
ISBN: 9401582777
Category : Medical
Languages : en
Pages : 248
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Book Description
Nearly three thousand papers and patents are dedicated to the actual or potential uses of cyclodextrins in pharmacy and pharmaceutical formulations. This is the first book written for pharmacists and pharmaceutical technologists which not only critically summarizes the enormous amount of literature available, but which can be used as a handbook when looking for solutions to practical problems. The fundamentals -- chemistry of cyclodextrins and their derivatives -- their physical and chemical properties are condensed to the most relevant items in Chapters 1 and 2. Chapter 3 deals with the adsorption, metabolism and toxicological properties of cyclodextrins. Chapter 4 explains the formulation, structure, composition and advantageous effects of the cyclodextrin inclusion complexes. Chapter 5 describes the methods for preparation and characterization of drug/cyclodextrin complexes. Chapters 6 and 7 are dedicated to the pharmacokinetics, biopharmaceutical and technological aspects of drug/CD complexes. Chapter 8 treats the application and effects of cyclodextrins in various drug formulations. The Appendix comprises a collection of recipes for any type of drug formulation. This book is aimed at those who use cyclodextrins in drug formulations, to improve the properties of existing drug formulations, or who want to prepare quite new formulations.
Author: Karl-Heinz Frömming
Publisher: Springer Science & Business Media
ISBN: 9401582777
Category : Medical
Languages : en
Pages : 248
Get Book Here
Book Description
Nearly three thousand papers and patents are dedicated to the actual or potential uses of cyclodextrins in pharmacy and pharmaceutical formulations. This is the first book written for pharmacists and pharmaceutical technologists which not only critically summarizes the enormous amount of literature available, but which can be used as a handbook when looking for solutions to practical problems. The fundamentals -- chemistry of cyclodextrins and their derivatives -- their physical and chemical properties are condensed to the most relevant items in Chapters 1 and 2. Chapter 3 deals with the adsorption, metabolism and toxicological properties of cyclodextrins. Chapter 4 explains the formulation, structure, composition and advantageous effects of the cyclodextrin inclusion complexes. Chapter 5 describes the methods for preparation and characterization of drug/cyclodextrin complexes. Chapters 6 and 7 are dedicated to the pharmacokinetics, biopharmaceutical and technological aspects of drug/CD complexes. Chapter 8 treats the application and effects of cyclodextrins in various drug formulations. The Appendix comprises a collection of recipes for any type of drug formulation. This book is aimed at those who use cyclodextrins in drug formulations, to improve the properties of existing drug formulations, or who want to prepare quite new formulations.
Author: Karl-Heinz Frömming
Publisher: Springer Science & Business Media
ISBN: 9780792321392
Category : Medical
Languages : en
Pages : 248
Get Book Here
Book Description
Nearly three thousand papers and patents are dedicated to the actual or potential uses of cyclodextrins in pharmacy and pharmaceutical formulations. This is the first book written for pharmacists and pharmaceutical technologists which not only critically summarizes the enormous amount of literature available, but which can be used as a handbook when looking for solutions to practical problems. The fundamentals -- chemistry of cyclodextrins and their derivatives -- their physical and chemical properties are condensed to the most relevant items in Chapters 1 and 2. Chapter 3 deals with the adsorption, metabolism and toxicological properties of cyclodextrins. Chapter 4 explains the formulation, structure, composition and advantageous effects of the cyclodextrin inclusion complexes. Chapter 5 describes the methods for preparation and characterization of drug/cyclodextrin complexes. Chapters 6 and 7 are dedicated to the pharmacokinetics, biopharmaceutical and technological aspects of drug/CD complexes. Chapter 8 treats the application and effects of cyclodextrins in various drug formulations. The Appendix comprises a collection of recipes for any type of drug formulation. This book is aimed at those who use cyclodextrins in drug formulations, to improve the properties of existing drug formulations, or who want to prepare quite new formulations.
Author: Karl-Heinz Fromming
Publisher:
ISBN: 9789401582780
Category :
Languages : en
Pages : 240
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Book Description
Author: Grégorio Crini
Publisher: Springer Nature
ISBN: 3030493083
Category : Science
Languages : en
Pages : 409
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Book Description
This book presents the historical development of Cyclodextrins by scientists who have made outstanding contribution to the field. Cyclodextrins are safe, cage-like molecules that have found major applications in many industrial sectors such as medicine, food, agriculture, environment and chemistry.
Author: Thao M. Ho
Publisher: Springer Nature
ISBN: 3030800563
Category : Technology & Engineering
Languages : en
Pages : 343
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Book Description
Cyclodextrins (CD) are cyclic oligosaccharides containing 6, 7 or 8 glucose units (α, β or γ-CD, respectively) in a truncated molecular shape. Their cyclic molecular structure contains a hydrophilic surface and a hydrophobic cavity at the center that can interact (host) with external hydrophobic compounds (guest molecules). Cyclodextrins have been categorized as Generally Recognized As Safe (GRAS) in the USA, “natural products” in Japan, and as “novel food” in Australia, New Zealand and EU countries. They are therefore widely used in food production to encapsulate hydrophobic compounds, including solid, liquid and gas molecules, in order to solubilize, stabilize or control the release rate of these components. To date, there has been no comprehensive review of the very large number of studies performed on encapsulation using cyclodextrin powders for food applications in recent years. This text fills that gap for academics in the encapsulation field and for industry professionals who want to gain a solid understanding of encapsulation functionality of cyclodextrin powders. The book consists of 16 chapters in which chapter 1 introduces cyclodextrin properties and its applications in food processing, and chapters 2-16 explore applications of cyclodextrin in encapsulation for many guest compounds. These compounds include gases, flavors, colors, pigments, polyphenols (plant bioactive compounds), essential oils, lipids (cholesterol and polyunsaturated fatty acids), vitamins, fruit ripening controlling compounds, and antifungal and antimicrobial compounds. These chapters also discuss functionalities of cyclodextrin in packaging, masking off-flavor and off-taste, and as dietary fiber. Covering a broad range of cyclodextrin applications and suitable for both newcomers to encapsulation technology and those with experience, Functionality of Cyclodextrins in Encapsulation for Food Applications is a unique and essential reference on this increasingly important topic.
Author: Erem Bilensoy
Publisher: John Wiley & Sons
ISBN: 0470934611
Category : Science
Languages : en
Pages : 626
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Book Description
Cyclodextrins in Pharmaceutics, Cosmetics, and Biomedicine covers a wide range of knowledge on cyclodextrins, from an overview of molecular and supramolecular aspects of cyclodextrin physicochemistry, to the latest outcomes in cyclodextrin use and future possibilities in the employment of these systems. This book focuses on the derivatives and physicochemical and biological properties of cyclodextrins, and considers drug delivery through topical, mucosal, and oral via cyclodextrin complexes.
Author: J. Szejtli
Publisher: Springer Science & Business Media
ISBN: 9401154481
Category : Medical
Languages : en
Pages : 688
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Book Description
This volume contains the proceedings of the Eighth International Symposium on Cyclodextrins, held in Budapest, Hungary, March 31-April 2, 1996. The 147 papers collected here are milestones in the exponentially increasing cyclodextrin literature, and represent a summary of the last two years' achievement in this field, with applications in such diverse disciplines as pharmaceuticals, food, cosmetics, textiles, plastics, and chromatography. Some highlights: lipophilicity profiles of cyclodextrins by computer molecular graphics; recent toxicological studies on cyclodextrins; Buckminsterfullerene/cyclodextrin complexes; hydroxypropyl-beta-cyclodextrin; pharmacokinetics and toxicology; peracylated cyclodextrins as drug carriers; cyclodextrins in nasal drug delivery; textile fibre surface modification by a reactive cyclodextrin; cyclodextrin-containing fabric care products; drug targeting by cyclodextrin-dimers for photodynamic cancer therapy; cyclodextrins in ophthalmologic drugs; new cyclodextrin derivatives and their potentials. Audience: This book will be of interest to researchers whose work involves pharmaceuticals, food chemicals and flavours, food additives, chromatographic methods, and biotechnology, as well as fundamental cyclodextrin research.
Author: Kishan Gopal Ramawat
Publisher: Springer
ISBN: 9783319162973
Category : Science
Languages : en
Pages : 0
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Book Description
This authoritative reference work presents comprehensive information about one of the most important and most wide-spread classes of (bio)organic compounds: the polysaccharides. The comprehensive and thoroughly up-to-date handbook presents the sources, identification, analysis, biosynthesis, biotechnology and applications of important polysaccharides likes starches, cellulose, chitin, gum and microbial polysaccharides. Polysaccharides can exhibit complex structure and various functional activities. These bio macromolecules can therefore serve as raw materials for various different materials, e.g. rayon, cellulose acetate, celluloid and nitrocellulose; and they find multiple applications, for instance as surgical threads (chitin), as sources of energy, dietary fibers, as blood flow adjuvants, in cosmetics, emulsion stabilizers, film formers, binders, viscosity increasing agents or skin conditioning agenta, as food additives in gums, chewing gum bases and as vaccines. Polysaccharides form the basis for useful products, like xanthan gum, dextran, welan gum, gellan gum, diutan gum and pullulan. Some of the polysaccharide-derived products have interesting and useful properties and show biological activities, such as immunomodulatory, antibacterial, anti-mutagenic, radioprotective, anti-oxidative, anti-ulcer, antidepressant, anti-septicaemic or anti-inflammatory activities. All these applications and properties of polysaccharides are for the first time compiled in a thorough and comprehensive overview in the present work. This reference work is organized thematically in four parts: Part I. Polysaccharides: Occurrence, Structure, Distribution and Biotechnology. Part II. Methods. Part III. Bioactive Polysaccharides. Part IV. Polysaccharides as Food. This reference work is edited by experienced experts, all chapters are written by well recognized international specialists. It is useful to all those working in the field of botany, phytochemistry, pharmacy, drug delivery, molecular biology, metabolomics, forestry, environment, conservation, biotechnology and NGOs working for forest protection.
Author: Francesco Trotta
Publisher: John Wiley & Sons
ISBN: 3527341013
Category : Technology & Engineering
Languages : en
Pages : 364
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Book Description
An excellent overview of the field, covering in detail a wide range of different types of constituent materials, such as polymers, metals and metal oxides. It discusses their production and synthetic routes, as well as applications in several areas, including catalysis, drug delivery and environmental science. A must-have for scientists in academia and industry, as well as a valuable resource for both newcomers and more established researchers working in the field.
Author: Zheng-Yu Jin
Publisher: World Scientific
ISBN: 9814436801
Category : Science
Languages : en
Pages : 290
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Book Description
Cyclodextrin Chemistry covers the preparation of cyclodextrins and cyclodextrin derivatives (CDs), and their applications in industrial and non-industrial areas. An overall theme in the book is the screening of cyclodextrin glycosyltransferase (CGTase), the preparation of sugar-branched cyclodextrins and CDs, and the use of CDs for reconstructing various supermolecule systems. The specific content also includes preparation methods, spectroscopy techniques for CDs analysis, and potential applications in food packaging, nutrient fortification, medicine, cosmetics, textiles, chemicals, feed, agriculture, and environment. It summarizes the research merit of CDs in the past twenty years and also emphasizes hot topics and important areas of cyclodextrin chemistry in the future. Contents: Introduction (Jun-Rong Huang, Hai-Ning Zhuang and Zheng-Yu Jin); Enzymes in Preparing Cyclodextrins (Sheng-Jun Wu, Xiu-Ting Hu, Jin-Moon Kim and Jing Chen); Preparation and Analysis of Cyclodextrin (An-Wei Cheng, Jin-Peng Wang and Zheng-Yu Jin); Preparation of Branched-Cyclodextrins (Xing Zhou, Yao-Qi Tian and Zheng-Yu Jin); Preparation and Analysis of Cyclodextrin Derivatives (Chao Yuan, Yu-Xiang Bai and Zheng-Yu Jin); Basic Application of Cyclodextrins in Supermolecule Chemistry (Tao Feng, Ai-Quan Jiao and Zheng-Yu Jin); Use of Cyclodextrins in Food, Pharmaceutical and Cosmetic Industries (Yao-Qi Tian, Xing Zhou and Zheng-Yu Jin); Application of Cyclodextrins in Non-industrial Areas (Xue-Hong Li and Zheng-Yu Jin). Readership: Researchers and technicians in food, pharmaceutical, cosmetic and chemical industries, as well as in non-industry areas such as agriculture and environmental engineering, supermolecule and analytical chemistry.
