Customized Artificial Implants: Bionic Design and Multiscale Evaluation

Customized Artificial Implants: Bionic Design and Multiscale Evaluation PDF Author: Zhenxian Chen
Publisher: Frontiers Media SA
ISBN: 2832549454
Category : Science
Languages : en
Pages : 185

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Book Description
Artificial implants have been commonly used to replace or fix damaged tissue in orthopedics. However, due to the inter-individual differences and the complexities of anatomical structures and load conditions, traditional implants cannot meet the clinical requirements. In recent years, questions relating to customized artificial implants have been getting more and more attention from the research community. Challenges to implementing precision design and evaluation arise not only from the design need of considering bionic structures, kinematical function, mechanical performances, and biological functional similarity but also from the multiscale comprehensive evaluation, the latter involves biomechanics and biotribology of musculoskeletal systems from macro musculoskeletal multibody dynamics to micromechanics of porous structures. Established analysis technologies such as musculoskeletal multibody dynamics modeling and neuromusculoskeletal modeling are being well developed and evolved through combining/coupling with finite element analyses and, more recently, by novel artificial intelligence approaches.

Organ Manufacturing

Organ Manufacturing PDF Author: Xiaohong Wang
Publisher: Nova Science Publishers
ISBN: 9781634829571
Category : Artificial organs
Languages : en
Pages : 0

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Book Description
This is the first time that human organs, such as the heart, liver, kidney, stomach, uterus, skin, lung, pancreas and breast can be manufactured automatically and precisely for clinical transplantation, drug screening and metabolism model establishment. Headed by Professor Xiaohong Wang (also the founder and director) in the Center of Organ Manufacturing, Department of Mechanical Engineering, Tsinghua University, this group has focused on organ manufacturing for over ten years. A series of technical bottleneck problems, such as vascular and nerve system establishment in a construct, multiple cell types and material system incorporation, and stem cell sequential engagement, have been overcome one by one. Two technical approaches have been exploited extensively. One is multiple nozzle rapid prototyping (RP), additive manufacturing (AM), or three-dimension (3D) printing. The other is combined mold systems. More than 110 articles and 40 patents with a series of theories and practices have been published consequently. In the future, all the failed organs (including the brain) in the human body can be substituted easily like a small accessory part in a car. Everyone can get benefit from these techniques, which ultimately means that the lifespan of humans, therefore, can be greatly prolonged from this time point. This book examines the progress made in the field and the developments made by these researchers (and authors) in the field.

Adaptive Gait and Postural Control: From Physiological to Pathological Mechanisms, Towards Prevention and Rehabilitation

Adaptive Gait and Postural Control: From Physiological to Pathological Mechanisms, Towards Prevention and Rehabilitation PDF Author: Helena Blumen
Publisher: Frontiers Media SA
ISBN: 2889636267
Category :
Languages : en
Pages : 346

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Book Description


Converging Technologies for Improving Human Performance

Converging Technologies for Improving Human Performance PDF Author: Mihail C. Roco
Publisher: Springer Science & Business Media
ISBN: 9401703590
Category : Technology & Engineering
Languages : en
Pages : 477

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Book Description
M. C. Roco and W.S. Bainbridge In the early decades of the 21st century, concentrated efforts can unify science based on the unity of nature, thereby advancing the combination of nanotechnology, biotechnology, information technology, and new technologies based in cognitive science. With proper attention to ethical issues and societal needs, converging in human abilities, societal technologies could achieve a tremendous improvement outcomes, the nation's productivity, and the quality of life. This is a broad, cross cutting, emerging and timely opportunity of interest to individuals, society and humanity in the long term. The phrase "convergent technologies" refers to the synergistic combination of four major "NBIC" (nano-bio-info-cogno) provinces of science and technology, each of which is currently progressing at a rapid rate: (a) nanoscience and nanotechnology; (b) biotechnology and biomedicine, including genetic engineering; (c) information technology, including advanced computing and communications; (d) cognitive science, including cognitive neuroscience. Timely and Broad Opportunity. Convergence of diverse technologies is based on material unity at the nanoscale and on technology integration from that scale.

Advances on Mechanics, Design Engineering and Manufacturing

Advances on Mechanics, Design Engineering and Manufacturing PDF Author: Benoit Eynard
Publisher: Springer
ISBN: 3319457810
Category : Technology & Engineering
Languages : en
Pages : 1208

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Book Description
This book gathers papers presented at the International Joint Conference on Mechanics, Design Engineering and Advanced Manufacturing (JCM 2016), held on 14-16 September, 2016, in Catania, Italy. It reports on cutting-edge topics in product design and manufacturing, such as industrial methods for integrated product and process design; innovative design; and computer-aided design. Further topics covered include virtual simulation and reverse engineering; additive manufacturing; product manufacturing; engineering methods in medicine and education; representation techniques; and nautical, aeronautics and aerospace design and modeling. The book is divided into eight main sections, reflecting the focus and primary themes of the conference. The contributions presented here will not only provide researchers, engineers and experts in a range of industrial engineering subfields with extensive information to support their daily work; they are also intended to stimulate new research directions, advanced applications of the methods discussed, and future interdisciplinary collaborations.

Machine Learning Approaches to Human Movement Analysis

Machine Learning Approaches to Human Movement Analysis PDF Author: Matteo Zago
Publisher: Frontiers Media SA
ISBN: 2889665615
Category : Science
Languages : en
Pages : 328

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Book Description


Coatings for Biomedical Applications

Coatings for Biomedical Applications PDF Author: Mike Driver
Publisher: Elsevier
ISBN: 0857093673
Category : Science
Languages : en
Pages : 381

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Book Description
The biomaterials sector is rapidly expanding and significant advances have been made in the technology of biomedical coatings and materials, which provide a means to improve the wear of joints, change the biological interaction between implant and host and combine the properties of various materials to improve device performance. Coatings for biomedical applications provides an extensive review of coating types and surface modifications for biomedical applications.The first part of the book explores a range of coating types and their biomedical applications. Chapters look at hydrophilic, mineral and pyrolytic carbon coatings in and ex vivo orthopaedic applications and finally at surface modification and preparation techniques. Part two presents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices.With its clear structure and comprehensive review of research, Coatings for biomedical applications is a valuable resource to researchers, scientists and engineers in the biomedical industry. It will also benefit anyone studying or working within the biomedical sector, particularly those specialising in biomedical coatings. - Provides an extensive review of coating types and surface modifications for biomedical applications - Chapters look at hydrophilic coatings for biomedical applications in and ex vivo, mineral coatings for orthopaedic applications, pyrolytic carbon coating and other commonly-used biomedical coatings - Presents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices

Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering

Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering PDF Author: Lisa C. du Toit
Publisher: Elsevier
ISBN: 0128184728
Category : Technology & Engineering
Languages : en
Pages : 318

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Book Description
Advanced 3D-Printed Systems and Nanosystems for Drug Delivery and Tissue Engineering explores the intricacies of nanostructures and 3D printed systems in terms of their design as drug delivery or tissue engineering devices, their further evaluations and diverse applications. The book highlights the most recent advances in both nanosystems and 3D-printed systems for both drug delivery and tissue engineering applications. It discusses the convergence of biofabrication with nanotechnology, constructing a directional customizable biomaterial arrangement for promoting tissue regeneration, combined with the potential for controlled bioactive delivery. These discussions provide a new viewpoint for both biomaterials scientists and pharmaceutical scientists. - Shows how nanotechnology and 3D printing are being used to create systems which are intelligent, biomimetic and customizable to the patient - Explores the current generation of nanostructured 3D printed medical devices - Assesses the major challenges of using 3D printed nanosystems for the manufacture of new pharmaceuticals

Mechanical Behavior of Materials

Mechanical Behavior of Materials PDF Author: Marc A. Meyers
Publisher:
ISBN: 9780511573422
Category : Strength of materials
Languages : en
Pages : 856

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Book Description
Includes numerous examples and problems for student practice, this textbook is ideal for courses on the mechanical behaviour of materials taught in departments of mechanical engineering and materials science.

Computer-Aided Tissue Engineering

Computer-Aided Tissue Engineering PDF Author: Michael A.K. Liebschner
Publisher: Humana Press
ISBN: 9781617797637
Category : Science
Languages : en
Pages : 0

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Book Description
The recent revolution in the biological sciences and bioengineering, along with the advancements of modern design and manufacturing, biomaterials, biology, and biomedicine, have brought about the new field of computer-aided tissue engineering. Advances in this fascinating new area of study encompass broad applications in large-scale tissue engineering fabrication, artificial organs, orthopaedic implants, and biological chips. Computer-Aided Tissue Engineering highlights the interdisciplinary nature of this topic and reviews the current state of computer-aided three-dimensional tissue modeling, tissue classification, and tissue fabrication and implantation. Particular focus is placed on rapid prototyping and direct digital fabrication for cell and organs, construction of tissue analogs, and precursors to 3D tissue scaffolds. Written for the highly successful Methods in Molecular BiologyTM series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Current and practical, Computer-Aided Tissue Engineering provides a coherent framework for researchers interested in these vital technologies and for clinicians who plan to implement them.