How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease PDF Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728

Get Book Here

Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease PDF Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728

Get Book Here

Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Current Catalog

Current Catalog PDF Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1628

Get Book Here

Book Description
First multi-year cumulation covers six years: 1965-70.

Handbook of Toxicology

Handbook of Toxicology PDF Author: Michael J. Derelanko
Publisher: CRC Press
ISBN: 1420042076
Category : Medical
Languages : en
Pages : 1381

Get Book Here

Book Description
LOCATE FREQUENTLY USED INFORMATION EASILY AND QUICKLY Working in the laboratory or office, you use a diverse assortment of basic information to design, conduct, and interpret toxicology studies and to perform risk assessments. The Second Edition of the best-selling Handbook of Toxicology gives you the information you need in a single referen

Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells

Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells PDF Author: T.E. Gram
Publisher: Elsevier
ISBN: 1483287629
Category : Medical
Languages : en
Pages : 325

Get Book Here

Book Description
Research has shown that the lung is capable of metabolically activating xenobiotics into intermediates that can covalently bind to pulmonary tissue. Further, it has been shown that the lung consists of many distinct cell types with the ability to take up and sequester metabolically unchanged drugs and chemicals that are ultimately toxic in effect. This volume reflects the extent of these developments and provides a state-of-the art reference in a rapidly evolving field incorporating both drug metabolism and pulmonary toxicology research.

National Library of Medicine Current Catalog

National Library of Medicine Current Catalog PDF Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 988

Get Book Here

Book Description


Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems

Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems PDF Author: Kamal Dua
Publisher: Academic Press
ISBN: 0128208880
Category : Technology & Engineering
Languages : en
Pages : 620

Get Book Here

Book Description
Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking down to the nanoscale level for an efficient system of targeting and managing respiratory disease. The book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, the book then focuses on current trends in disease pathology that use different in vitro and in vivo models. The comprehensive resource is designed for those new to the field and to specialized scientists and researchers involved in pulmonary research and drug development. - Explores recent perspectives and challenges regarding the management and diagnosis of chronic respiratory diseases - Provides insights into how advanced drug delivery systems can be effectively formulated and delivered for the management of various pulmonary diseases - Includes the most recent information on diagnostic methods and treatment strategies using controlled drug delivery systems (including nanotechnology)

The NLM Technical Bulletin

The NLM Technical Bulletin PDF Author:
Publisher:
ISBN:
Category : Medical libraries
Languages : en
Pages : 394

Get Book Here

Book Description


Inflammation

Inflammation PDF Author: Robert R. Ruffolo, Jr.
Publisher: CRC Press
ISBN: 9780849394737
Category : Medical
Languages : en
Pages : 224

Get Book Here

Book Description
Inflammation: Mediators and Pathways reviews key developments in the field of inflammation. It focuses on novel pathways of inflammation that have only recently surfaced. All the topics covered are currently the subject of intense investigation, and all contributors are established investigators in the field.

Current Topics in Pulmonary Pharmacology and Toxicology

Current Topics in Pulmonary Pharmacology and Toxicology PDF Author: Mannfred A. Hollinger
Publisher:
ISBN:
Category :
Languages : en
Pages : 288

Get Book Here

Book Description


Neuropeptides in Respiratory Medicine

Neuropeptides in Respiratory Medicine PDF Author: Michael A. Kaliner
Publisher: CRC Press
ISBN: 9780824791995
Category : Science
Languages : en
Pages : 718

Get Book Here

Book Description
"This outstanding resource offers comprehensive presentations of the latest basic knowledge and the most advanced research on neuropeptides of the respiratory tract covering the structure, receptors, molecular biology, and function of each important neuropeptide and examining how they relate to disease. Demonstrates the utility of immunohistochemistry, autoradiography, molecular biology, smooth muscle contraction, and glandular secretion for the study of neural function both in vitro and in vivo!"