Curcumin in Health and Disease

Curcumin in Health and Disease PDF Author: Beatrice E. Bachmeier
Publisher: MDPI
ISBN: 3039214497
Category : Medical
Languages : en
Pages : 274

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Book Description
The plant-derived polyphenol curcumin has been used in promoting health and combating disease for thousands of years. Its therapeutic effects have been successfully utilized in Ayurvedic and Traditional Chinese Medicine in order to treat inflammatory diseases. Current results from modern biomolecular research reveal the modulatory effects of curcumin on a variety of signal transduction pathways associated with inflammation and cancer. In this context, curcumin’s antioxidant, anti-inflammatory, anti-tumorigenic, and even anti-metastatic activities are discussed. On the cellular level, the reduced activity of several transcription factors (such as NFkB or AP-1) and the suppression of inflammatory cytokines, matrix degrading enzymes, metastasis related genes and even microRNAs are reported. On functional levels, these molecular effects translate into reduced proliferative, invasive, and metastatic capacity, as well as induced tumor cell apoptosis. All these effects have been observed not only in vitro but also in animal models. In combination with anti-neoplastic drugs like Taxol, kinase inhibitors, and radiation therapy, curcumin potentiates the drugs’ therapeutic power and can protect against undesired side effects. Natural plant-derived compounds like curcumin have one significant advantage: They do not usually cause side effects. This feature qualifies curcumin for primary prevention in healthy persons with a predisposition to cancer, arteriosclerosis, or chronic inflammatory diseases. Nonetheless, curcumin is considered safe, although potential toxic effects stemming from high dosages, long-term intake, and pharmacological interactions with other compounds have yet to be assessed. This Special Issue examines in detail and updates current research on the molecular targets, protective effects, and modes of action of natural plant-derived compounds and their roles in the prevention and treatment of human diseases.

Curcumin in Health and Disease

Curcumin in Health and Disease PDF Author: Beatrice E. Bachmeier
Publisher: MDPI
ISBN: 3039214497
Category : Medical
Languages : en
Pages : 274

Get Book Here

Book Description
The plant-derived polyphenol curcumin has been used in promoting health and combating disease for thousands of years. Its therapeutic effects have been successfully utilized in Ayurvedic and Traditional Chinese Medicine in order to treat inflammatory diseases. Current results from modern biomolecular research reveal the modulatory effects of curcumin on a variety of signal transduction pathways associated with inflammation and cancer. In this context, curcumin’s antioxidant, anti-inflammatory, anti-tumorigenic, and even anti-metastatic activities are discussed. On the cellular level, the reduced activity of several transcription factors (such as NFkB or AP-1) and the suppression of inflammatory cytokines, matrix degrading enzymes, metastasis related genes and even microRNAs are reported. On functional levels, these molecular effects translate into reduced proliferative, invasive, and metastatic capacity, as well as induced tumor cell apoptosis. All these effects have been observed not only in vitro but also in animal models. In combination with anti-neoplastic drugs like Taxol, kinase inhibitors, and radiation therapy, curcumin potentiates the drugs’ therapeutic power and can protect against undesired side effects. Natural plant-derived compounds like curcumin have one significant advantage: They do not usually cause side effects. This feature qualifies curcumin for primary prevention in healthy persons with a predisposition to cancer, arteriosclerosis, or chronic inflammatory diseases. Nonetheless, curcumin is considered safe, although potential toxic effects stemming from high dosages, long-term intake, and pharmacological interactions with other compounds have yet to be assessed. This Special Issue examines in detail and updates current research on the molecular targets, protective effects, and modes of action of natural plant-derived compounds and their roles in the prevention and treatment of human diseases.

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease PDF Author: Bharat B. Aggarwal
Publisher: Springer Science & Business Media
ISBN: 0387464018
Category : Medical
Languages : en
Pages : 502

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Book Description
The medicinal uses of Curcumin (also called turmeric) have been known and described for more than 5000 years. A large body of recent research suggests that curcumin is potentially useful in the treatment of inflammatory diseases, through modulation of numerous molecular targets. This is the first monograph to focus on the potential use of curcumin in the treatment of cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer’s, psoriasis and more.

Curcumin

Curcumin PDF Author: Jan McBarron
Publisher:
ISBN: 9780988386631
Category :
Languages : en
Pages : 66

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Book Description
Curcumin is a miracle nutrient that prevents and treats a wide variety of serious disease conditions, including: Osteoarthritis, back pain, fibromyalgia and other painful musculoskeletal conditions; Heart disease Diabetes Depression Alzheimer's disease Digestive disorders Obesity Lung and liver disease If this sounds far-fetched to you, consider the voluminous scientific validations of curcumin's power and the particular effectiveness of super-absorbable BCM-95 . This expanded second edition has extensive information on new research on curcumin and Alzheimer's disease prevention and treatment and an update on the latest research.

Curcumin: Nature's Answer to Cancer and Other Chronic Diseases

Curcumin: Nature's Answer to Cancer and Other Chronic Diseases PDF Author: Ajay Goel Ph D
Publisher: Take Charge Books
ISBN: 9780996158916
Category : Health & Fitness
Languages : en
Pages : 150

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Book Description
Curcumin is the answer to cancer and chronic health problems Have you: Been diagnosed with cancer? Had cancer and "recovered" only to fear its recurrence? Had a friend or loved one with cancer? Been diagnosed with diabetes or pre-diabetes? Struggled with your weight? Been depressed? Worried about your memory? Had high blood pressure, high triglycerides, high cholesterol or other signs of heart disease? Had joint pain or arthritis? Had digestive disorders like inflammatory or irritable bowel, chronic constipation or diarrhea or Crohn's disease? Curcumin offers the solution you need to prevent and even reverse these diseases to create a lifetime of vibrant health. Dr. Ajay Goel has spent more than 20 years researching the most effective natural means of combatting cancer and other chronic diseases."

Advanced Pharmacological Uses of Medicinal Plants and Natural Products

Advanced Pharmacological Uses of Medicinal Plants and Natural Products PDF Author: Singh, Ajeet
Publisher: IGI Global
ISBN: 1799820955
Category : Medical
Languages : en
Pages : 442

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Book Description
A vast majority of the world’s population lacks access to essential medicines and the provision of safe healthcare services. Medicinal plants and herbal medicines can be applied for pharmacognosy, or the discovery of new drugs, or as an aid for plant physiology studies. In recent years, there has been increased interest in the search for new chemical entities and the expression of resistance of many drugs available in the market has led to a shift in paradigm towards medicinal research. Herbal treatments, the most popular form of folk medicine, may become an important way of increasing access to healthcare services. Advanced Pharmacological Uses of Medicinal Plants and Natural Products provides emerging research exploring the theoretical and practical aspects of drug discovery from natural sources that allow for the effective treatment of human health problems without any side effects, toxicity, or drug resistance. Featuring coverage on a broad range of topics such as ethnobotany, therapeutic applications, and bioactive compounds, this book is ideally designed for pharmacologists, scientists, ethnobotanists, botanists, health researchers, professors, industry professionals, and health students in fields that include pharmaceutical drug development and discovery.

Chemistry and Bioactive Components of Turmeric

Chemistry and Bioactive Components of Turmeric PDF Author: Sreeraj Gopi
Publisher: Royal Society of Chemistry
ISBN: 1839160594
Category : Technology & Engineering
Languages : en
Pages : 310

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Book Description
Turmeric belongs to the family Zingiberaceae and is a yellow spice of high economic importance due to its medicinal value. Cultivated in tropical and sub-tropical regions around the world, it is used extensively as a colouring, flavouring and preserving agent. In recent years, several drugs derived from natural products have been developed and current drug research is actively investigating the possible therapeutic roles of many Ayurvedic medicines, most notable among those being examined is turmeric. The wide range of pharmacological activities attributed to turmeric come mainly from curcuminoids and two related compounds, demethoxycurcumin and bisdemethoxycurcumin. This comprehensive book brings together the research carried out on constituents obtained from turmeric and highlights their chemical and biological activities. Comprising 17 chapters, each written by experts in their respective field and curated by authorities, it will be invaluable to all those who are involved in the production, processing, marketing, and the use of turmeric. Appealing to researchers and professionals in natural products, nutraceuticals and food chemists, this book is exposing some of the myths and showing areas for possible future use.

Dietary Interventions in Liver Disease

Dietary Interventions in Liver Disease PDF Author: Ronald Ross Watson
Publisher: Academic Press
ISBN: 012814467X
Category : Science
Languages : en
Pages : 430

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Book Description
Dietary Interventions in Liver Disease: Foods, Nutrients, and Dietary Supplements provides valuable insights into the agents that affect metabolism and other health-related conditions in the liver. It provides nutritional treatment options for those suffering from liver disease. Information is presented on a variety of foods, including herbs, fruits, soy and olive oil, thus illustrating that variations in intake can change antioxidant and disease preventing non-nutrients that affect liver health and/or disease promotion. This book is a valuable resource for biomedical researchers who focus on identifying the causes of liver diseases and food scientists targeting health-related product development. - Provides information on agents that affect metabolism and other health-related conditions in the liver - Explores the impact of composition, including differences based on country of origin and processing techniques - Addresses the most positive results from dietary interventions using bioactive foods to impact liver disease, including reduction of inflammation and improved function

Turmeric

Turmeric PDF Author: P. N. Ravindran
Publisher: CRC Press
ISBN: 1420006320
Category : Science
Languages : en
Pages : 506

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Book Description
For the last 6000 years turmeric has been used in Ayurvedic medicine to alleviate pain, balance digestion, purify body and mind, clear skin diseases, expel phlegm, and invigorate the blood. Nowadays, this plant has acquired great importance with its anti-aging, anti-cancer, anti-Altzheimer, antioxidant, and a variety of other medicinal properties.

Curcumin

Curcumin PDF Author: Jun Sasaki
Publisher: Nova Science Publishers
ISBN: 9781619424876
Category : Turmeric
Languages : en
Pages : 278

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Book Description
Curcumin is a natural product found in the rhizome of Curcuma longa. Ongoing research and clinical trials prove this natural phenolic compound to possess diverse pharmacological potency and is effective as an antioxidant, anti-inflammatory, antimicrobial/antiviral property and is also being considered as a cancer chemo-preventive agent. Topics discussed in this book include the implications of curcumin treatment of central nervous system disease; phosphorylase kinase inhibition in skin disease; PEGylated curcumin; the potential role of curcumin as a chemotherapeutic drug and the pharmaceutical implications of curcumin in the development of drugs for cystic fibrosis pharmacotherapy.

Nutrition and Wound Healing

Nutrition and Wound Healing PDF Author: Joseph A. Molnar MD PhD FACS
Publisher: CRC Press
ISBN: 0203500237
Category : Medical
Languages : en
Pages : 378

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Book Description
With mounting evidence regarding the role of poor nutrition in the development of chronic diseases such as heart disease and diabetes, it is no secret that appropriate nutrition is crucial to optimal health. Achieving the correct balance of elements provides the body with the ability to adapt to a shifting and often hazardous environment. Never is