Author: Allan S. Myerson
Publisher: VCH
ISBN:
Category : Science
Languages : en
Pages : 440
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Book Description
Developed from a symposium sponsored by the International Chemical Congress of the Pacific Basin Societies, Honolulu, Hawaii, December 1989, this book presents the current research which will aid in the development, implementation, and improvement of crystallization as a separation and purification process. Sections cover basic studies, including crystal growth, nucleation, impurity-crystal interactions, and solution structure; crystallizer operation and control; crystallization of organic and biomolecules; and crystallization and precipitation of inorganic materials. Annotation copyrighted by Book News, Inc., Portland, OR
Author: Allan Myerson
Publisher: Butterworth-Heinemann
ISBN: 0080533515
Category : Technology & Engineering
Languages : en
Pages : 329
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Book Description
Crystallization is an important separation and purification process used in industries ranging from bulk commodity chemicals to specialty chemicals and pharmaceuticals. In recent years, a number of environmental applications have also come to rely on crystallization in waste treatment and recycling processes.The authors provide an introduction to the field of newcomers and a reference to those involved in the various aspects of industrial crystallization. It is a complete volume covering all aspects of industrial crystallization, including material related to both fundamentals and applications. This new edition presents detailed material on crystallization of biomolecules, precipitation, impurity-crystal interactions, solubility, and design.Provides an ideal introduction for industrial crystallization newcomers Serves as a worthwhile reference to anyone involved in the fieldCovers all aspects of industrial crystallization in a single, complete volume
Author: Alan G. Jones
Publisher: Butterworth-Heinemann
ISBN: 0750655208
Category : Science
Languages : en
Pages : 362
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Book Description
Particulate Crystal Characteristics; Fluid-particle Transport Processes; Crystallization Principles and Techniques; Crystal Formation Processes; Crystallizer Design and Operation; Solid-Liquid Separation Processes; Design of Crystallization Process Systems.
Author: Angelo Chianese
Publisher: John Wiley & Sons
ISBN: 3527645179
Category : Science
Languages : en
Pages : 253
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Book Description
Crystallization is an important technique for separation and purification of substances as well as for product design in chemical, pharmaceutical and biotechnological process industries. This ready reference and handbook draws on research work and industrial practice of a large group of experts in the various areas of industrial crystallization processes, capturing the essence of current trends, the markets, design tools and technologies in this key field. Along the way, it outlines trouble free production, provides laboratory controls, analyses case studies and discusses new challenges. First the instrumentation and techniques used to measure the crystal size distribution, the nucleation and solubility points, and the chemical composition of the solid and liquid phase are outlined. Then the main techniques adopted to control industrial crystallizers, starting from fundamental approaches to the most advanced ones, including the multivariable predictive control are described. An overview of the main crystallizer types is given with details of the main control schemes adopted in industry as well as the more suitable sensors and actuators.
Author: Nathan Micheal Aumock
Publisher:
ISBN:
Category :
Languages : en
Pages : 230
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Book Description
A process is proposed to perform separations via crystallization by using multiple tanks and constraining crystal growth to solid surfaces. Multiple tanks allow multiple recrystallizations to improve product purity and to ensure high recovery of the component of interest. Crystal growth on solid surfaces avoids multi-phase flow handling which can cause operational difficulties. A model is developed for this process for solid solution forming systems which is also applied to batch crystallization for comparison. The solid product from the process is found to provide enhanced purity (1-2% increase) at yields approaching the batch yield when a large number of tanks are used; the ratio of incorporation rate constants (?) is significantly less than one; and the surface equilibrium constant (K) is less than order one. The liquid effluent from the process is also a viable product when ?>1 and K is close to or greater than one. The use of a sweep stream entering at a tank up-stream of the feed tank was determined to be undesirable due to diminished yield. Batch experiments performed to validate the proposed model with asparagine as the component of interest and aspartic acid as the impurity in water were found to be inconclusive. Fitting of parameter values to the liquid phase was not successful due to crystal growth on surfaces other than the designated seed. The parameters ? and K fitted to solid phase data were found to be 0.1-3 and 0.4-0.6 respectively which are favorable parameters for use of the semi-continuous process with the solid taken as the product. The presence of crystals on multiple surfaces in the liquid phase indicates that constraint of crystallization to a specific surface was not achieved. The impurity distribution in the solid layer did not match the model prediction throughout the crystal. Non-uniform initial growth behavior or uneven dissolution of the crystal during analysis could cause the observed behavior. Further experiments should be conducted that in-crease the ratio of product to accumulation in the liquid phase and employ solid sampling methods that give more consistent results.
Author: Alison Lewis
Publisher: Cambridge University Press
ISBN: 1316299082
Category : Technology & Engineering
Languages : en
Pages : 354
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Book Description
Bridging the gap between theory and practice, this text provides the reader with a comprehensive overview of industrial crystallization. Newcomers will learn all of the most important topics in industrial crystallization, from key concepts and basic theory to industrial practices. Topics covered include the characterization of a crystalline product and the basic process design for crystallization, as well as batch crystallization, measurement techniques, and details on precipitation, melt crystallization and polymorphism. Each chapter begins with an introduction explaining the importance of the topic, and is supported by homework problems and worked examples. Real world case studies are also provided, as well as new industry-relevant information, making this is an ideal resource for industry practitioners, students, and researchers in the fields of industrial crystallization, separation processes, particle synthesis, and particle technology.
Author: Angelo Chianese
Publisher: John Wiley & Sons
ISBN: 3527331735
Category : Science
Languages : en
Pages : 253
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Book Description
Crystallization is an important technique for separation and purification of substances as well as for product design in chemical, pharmaceutical and biotechnological process industries. This ready reference and handbook draws on research work and industrial practice of a large group of experts in the various areas of industrial crystallization processes, capturing the essence of current trends, the markets, design tools and technologies in this key field. Along the way, it outlines trouble free production, provides laboratory controls, analyses case studies and discusses new challenges. First the instrumentation and techniques used to measure the crystal size distribution, the nucleation and solubility points, and the chemical composition of the solid and liquid phase are outlined. Then the main techniques adopted to control industrial crystallizers, starting from fundamental approaches to the most advanced ones, including the multivariable predictive control are described. An overview of the main crystallizer types is given with details of the main control schemes adopted in industry as well as the more suitable sensors and actuators.
Author: G. D. Botsaris
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 320
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Book Description
Covering a range of topics, this volume presents crystallization of polymorphs and the problems encountered in the separation of chiral compounds by selective crystallization, as well as aspects of the crystallization of amino acids, proteins, and pharmaceuticals. The introductory section includes state-of-the-art research on secondary nucleation, the mechanism for crystallization of proteins, kinetics of impurity effect on growth, and crystal morphology prediction. Other topics include the use of high-pressure crystallization in industrial processes, precipitation cases for organic and inorganic compounds, precipitation processes by antisolvents, fast reaction precipitation, and isoelectric precipitation.
Author: Panel on Separation Technology for Industrial Reuse and Recycling
Publisher: National Academies Press
ISBN: 0309592828
Category : Technology & Engineering
Languages : en
Pages : 128
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Book Description
Separation processesor processes that use physical, chemical, or electrical forces to isolate or concentrate selected constituents of a mixtureare essential to the chemical, petroleum refining, and materials processing industries. In this volume, an expert panel reviews the separation process needs of seven industries and identifies technologies that hold promise for meeting these needs, as well as key technologies that could enable separations. In addition, the book recommends criteria for the selection of separations research projects for the Department of Energy's Office of Industrial Technology.
Author: Susan R. Dye
Publisher:
ISBN:
Category : Crystallization
Languages : en
Pages : 422
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Book Description
