Craniofacial Development The Tissue and Molecular Interactions That Control Development of the Head PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Craniofacial Development The Tissue and Molecular Interactions That Control Development of the Head PDF full book. Access full book title Craniofacial Development The Tissue and Molecular Interactions That Control Development of the Head by Philippa H. Francis-West. Download full books in PDF and EPUB format.
Author: Philippa H. Francis-West
Publisher: Springer Science & Business Media
ISBN: 3642555705
Category : Science
Languages : en
Pages : 217
Get Book Here
Book Description
Craniofacial development is a multistep and intricate process initially involving a number of inductive interactions that control neural and neural crest development, which are followed by a series of epithelial-mesenchymal interactions that control outgrowth, patterning, and skeletal differentiation. Certain aspects of craniofacial development are unique developmental processes in higher vertebrates. First, in higher vertebrates the cranial neural crest, in contrast to the trunk neural crest, gives rise to the skeletal structures. These skeletal elements include those comprising mem brane bone and secondary cartilage, which with the exception of the clavicle are tissue types found exclusively in the head in higher vertebrates. Second, with the exception of the tongue, the origin of the musculature is distinct from other regions of the body. The body and tongue muscles are formed from the segmented epithelial somites whilst the head musculature is formed from unsegmented paraxial and prechordal mesoderm. Furthermore, the signalling cascades that control myogenic differentia tion appear to be distinct as determined by gene expression and the response of myogenic cells to growth factors. Finally, the neurogenic placodes, which give rise to the sensory organs and some cranial ganglia, are only found in the head. Over recent years, there have been significant advances in our knowledge of the molecular proc esses that control craniofacial development in a number of animal models. This has given insight into the genes that control many aspects of head development from the initial induction of the head to the final stages of differentiation.
Author: Philippa H. Francis-West
Publisher: Springer Science & Business Media
ISBN: 3642555705
Category : Science
Languages : en
Pages : 217
Get Book Here
Book Description
Craniofacial development is a multistep and intricate process initially involving a number of inductive interactions that control neural and neural crest development, which are followed by a series of epithelial-mesenchymal interactions that control outgrowth, patterning, and skeletal differentiation. Certain aspects of craniofacial development are unique developmental processes in higher vertebrates. First, in higher vertebrates the cranial neural crest, in contrast to the trunk neural crest, gives rise to the skeletal structures. These skeletal elements include those comprising mem brane bone and secondary cartilage, which with the exception of the clavicle are tissue types found exclusively in the head in higher vertebrates. Second, with the exception of the tongue, the origin of the musculature is distinct from other regions of the body. The body and tongue muscles are formed from the segmented epithelial somites whilst the head musculature is formed from unsegmented paraxial and prechordal mesoderm. Furthermore, the signalling cascades that control myogenic differentia tion appear to be distinct as determined by gene expression and the response of myogenic cells to growth factors. Finally, the neurogenic placodes, which give rise to the sensory organs and some cranial ganglia, are only found in the head. Over recent years, there have been significant advances in our knowledge of the molecular proc esses that control craniofacial development in a number of animal models. This has given insight into the genes that control many aspects of head development from the initial induction of the head to the final stages of differentiation.
Author: George T.J. Huang
Publisher: John Wiley & Sons
ISBN: 1118279239
Category : Science
Languages : en
Pages : 578
Get Book Here
Book Description
Stem Cells, Craniofacial Development and Regeneration is an introduction to stem cells with an emphasis on their role in craniofacial development. Divided into five sections, chapters build from basic introductory information on the definition and characteristics of stem cells to more indepth explorations of their role in craniofacial development. Section I covers embryonic and adult stem cells with a focus on the craniofacial region, while sections II-IV cover the development and regeneration of craniofacial bone, tooth, temporomandibular joint, salivary glands and muscle. Concluding chapters describe the current, cutting-edge research utilizing stem cells for craniofacial tissue bioengineering to treat lost or damaged tissue. The authoritative resource for dentistry students as well as craniofacial researchers at the graduate and post-graduate level, Stem Cells, Craniofacial Development and Regeneration explores the rapidly expanding field of stem cells and regeneration from the perspective of the dentistry and craniofacial community, and points the way forward in areas of tissue bioengineering and craniofacial stem cell therapies.
Author: Sebastian Dworkin
Publisher:
ISBN: 9781071618479
Category : Facial bones
Languages : en
Pages : 313
Get Book Here
Book Description
This volume explores scientific methodologies currently employed to integrate observational developmental biology, tissue explant and cell-based approaches and genetic/molecular technologies to develop a holistic understanding of craniofacial development. Chapters guide readers through the use of disparate models to study formation of the head and face (c. elegans, zebrafish, mouse, alongside human imaging approaches), together with cell culture, tissue explant and in vivo cell imaging and analysis techniques. At the molecular level, chapters include analysing gene expression using in-situ hybridisation and single-cell RNA-Sequencing (scRNA-SEQ), as well as genetic modification techniques such as CRISPR/Cas9-mediated deletion. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Craniofacial Development: Methods and Protocols aims to be a guide in the field of craniofacial development for senior and new researchers looking to expand their existing research programs to encompass novel techniques. .
Author: Geoffrey H. Sperber, Geoffrey D. Guttmann, Steven M. Sperber
Publisher: PMPH-USA
ISBN: 9781550091274
Category : Medical
Languages : en
Pages : 236
Get Book Here
Book Description
The accompanying CD-ROM includes the complete text and illustrations from the print volume, as well as three-dimensional movies that show reconstructions of embryos.
Author: Andrew D. Dixon
Publisher: CRC Press
ISBN: 1351446657
Category : Science
Languages : en
Pages : 500
Get Book Here
Book Description
This book brings together in one volume selected important topics in craniofacial growth. Topics include: principles of skeletal growth; osteogenesis and its control; formation of the cranial base and craniofacial joints; prenatal development of the facial skeleton; growth of the mandible, nasomaxillary complex, orbit, cranial base, ear capsule, and cranial vault; bone remodeling; muscles; soft tissues; and blood vessels. Fundamentals of Craniofacial Growth contains detailed illustrations and extensive reference lists. Independently authored chapters provide comprehensive reviews encompassing both contemporary and historical perspectives. In addition to medicine and dentistry, contributors provide expertise from such diverse backgrounds as anatomy, biology, biomathematics, embryology, orthodontics, physical anthropology, and plastic and reconstructive surgery.
Author: Sridhar Premkumar
Publisher: JP Medical Ltd
ISBN: 9350251825
Category : Medical
Languages : en
Pages : 397
Get Book Here
Book Description
Textbook of Craniofacial Growth is a "one stop" guide to craniofacial growth and development, for both undergraduate and postgraduate students. The book begins with the basics - biology of bone and cartilage, physiology of bone and craniofacial growth and development. Assisted by comprehensive flow charts and well-illustrated diagrams, the text then examines control mechanisms, development of dentition, temporomandibular joint, mycology, neuromuscular reflexes and the maturation of orofacial functions. Craniofacial anomalies and the influence of genetics on growth are also discussed, guiding students through normal versus subnormal growth.
Author: Erika Kuchler
Publisher: Frontiers Media SA
ISBN: 2889714713
Category : Science
Languages : en
Pages : 191
Get Book Here
Book Description
Author: Geoffrey H. Sperber
Publisher: Pmph USA Limited
ISBN: 9781607952824
Category : Facial bones
Languages : en
Pages : 276
Get Book Here
Book Description
The field of embryology has experienced a period of explosive growth since the previous edition of this book was published nearly a decade ago. The insights of genetic expression in determining the unfolding of the embryonic layers have revolutionised our understanding of some of the mechanisms of embryogenesis. As implied by the title of the new edition, Craniofacial Embryogenetics and Development, genetics is linked with embryology in this text. Virtually all embryological development has an underlying genetic component, and the basic science of genetics is the key in uncovering the many mysteries of embryogenesis. The tools of molecular genetics have provided insights into developmental mechanisms that allow us the ability to identify transient regions of genetic expression patterns. Unraveling the precise biochemical and mechanical interactions of discrete regions in the unfolding embryonic components remains a dauntingly-complex challenge to understanding the conversion of the genome into the phenome. The addition of genetic information gleaned from other mammalian species might aid in dissecting human embryology into comprehensible components to understand normal and abnormal development. This new edition is dedicated to this objective and will prove invaluable to plastic and orofacial surgeons, otolaryngologists, orthodontists, neonatal pediatricians, speech pathologists, teratologists, embryologists, and anatomists. Key Features: Provides clinicians with a basic background for assessing and treating craniofacial anomalies. Describes recent technical advances in optical projection tomography, photoacoustic and 3D imaging, small-angle X-ray scattered (SAXS) tomography and morphometrics and their impact on embryogenetics.
Author: Agnes Bloch-Zupan
Publisher: Elsevier
ISBN: 0124160387
Category : Medical
Languages : en
Pages : 265
Get Book Here
Book Description
Dental defects may be the physical expression of genetic defects, and so they can often be seen in a variety of syndromes associated with malformations of organs. However, dental defects are often not recognized, identified, nor characterised despite representing a possible diagnostic sign for an undiagnosed condition. This book addresses this gap by providing an understanding of dental genetics and its developmental biology counterpart. With approximately seventy well-illustrated examples, the authors present the clinical oro-facial manifestations accompanying various syndromes, providing the necessary knowledge for diagnostic purposes, as well as giving insight into recent development for each specific condition. The clarity and format of this book make it an ideal support guide both in the clinic and while conducting research. Comprehensive examination of dento/oro/craniofacial anomalies Well-illustrated examples Presented in a compact, easy to use format
Author: Linda K. McLoon
Publisher: Springer Science & Business Media
ISBN: 1461444659
Category : Medical
Languages : en
Pages : 339
Get Book Here
Book Description
Of the approximately 640 muscles in the human body, over 10% of them are found in the craniofacial region. The craniofacial muscles are involved in a number of crucial non-locomotor activities, and are critical to the most basic functions of life, including vision, taste, chewing and food manipulation, swallowing, respiration, speech, as well as regulating facial expression and controlling facial aperture patency. Despite their importance, the biology of these small skeletal muscles is relatively unexplored. Only recently have we begun to understand their unique embryonic development and the genes that control it and characteristic features that separate them from the skeletal muscle stereotype. This book is the most comprehensive reference to date on craniofacial muscle development, structure, function, and disease. It details the state-of-the-art basic science of the craniofacial muscles, and describes their unique response to major neuromuscular conditions. Most importantly, the text highlights how the craniofacial muscles are different from most skeletal muscles, and why they have been viewed as a distinct allotype. In addition, the text points to major gaps in our knowledge about these very important skeletal muscles and identified key gaps in our knowledge and areas primed for further study and discovery.
