Severe acute respiratory syndrome coronavirus 2: Host-pathogen interactions and cellular signaling - vol II PDF Download
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Author: Vikas Sood
Publisher: Frontiers Media SA
ISBN: 2832517390
Category : Science
Languages : en
Pages : 136
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Book Description
Author: Vikas Sood
Publisher: Frontiers Media SA
ISBN: 2832517390
Category : Science
Languages : en
Pages : 136
Get Book Here
Book Description
Author: Vikas Sood
Publisher: Frontiers Media SA
ISBN: 2889743462
Category : Science
Languages : en
Pages : 250
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Book Description
Author:
Publisher: Frontiers Media SA
ISBN: 2832515770
Category : Medical
Languages : en
Pages : 303
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Book Description
Author: Seshadri Vasan
Publisher: Frontiers Media SA
ISBN: 2832537944
Category : Science
Languages : en
Pages : 116
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Book Description
The ‘novel coronavirus disease’ (COVID-19) has caused significant global morbidity, mortality and economic damage on a scale similar to the influenza pandemic of 1918. The causative ‘severe acute respiratory syndrome virus 2’ (SARS-CoV-2) is a RNA virus which is evolving rapidly, accumulating mutations, and existing as a cloud of variants with quasispecies diversity. We have tens of thousands of variants, of which currently two are ‘variants of interest’ (Lambda, Mu) and another four ‘variants of concern’ (Alpha, Beta, Gamma, Delta, Omicron) to the World Health Organization (WHO). Variants of interest often emerge as variants under investigation in one or more countries, as seen with the Omicron (initially denoted as Nu in South Africa). They become variants of concern when there is evidence of increased transmissibility, greater case severity, loss of neutralization by antibodies, and reduced effectiveness of countermeasures. Some SARS-CoV-2 variants can infect new hosts (for instance, the Alpha, Beta and Gamma variants of concern can infect wild type mice which is a species that cannot be vaccinated or controlled easily), and/or reduce the effectiveness of vaccines and therapies (especially Beta and Delta); diagnostic tests have also been reported to be affected. Currently, we do not yet have any ‘variant of high consequence’ with confirmed attributes such as widespread diagnostic test failures, significant reduction in the effectiveness of vaccines and/or therapies, with greater disease severity and deaths. It remains to be seen if Omicron would be the first to be declared by the WHO as a variant of high consequence; more variants of concern are also likely to be declared by the WHO over the next couple of years. Therefore, our ability to control and conquer this pandemic over the long run is dependent on predicting and keeping up with the evolution of this virus, its new hosts, as well as understanding and mitigating its impact on diagnostics, vaccines and therapies.
Author: Gabriela Brenta
Publisher: Frontiers Media SA
ISBN: 2832541003
Category : Medical
Languages : en
Pages : 103
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Book Description
Author: Thomas Rawson
Publisher: Frontiers Media SA
ISBN: 2889764656
Category : Medical
Languages : en
Pages : 771
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Book Description
Almost nine months since the first recorded case, the novel betacoronovirus; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has now passed 18 million confirmed cases. The multi-disciplinary work of researchers worldwide has provided a far deeper understanding of COVID-19 pathogenesis, clinical treatment and outcomes, lethality, disease-spread dynamics, period of infectivity, containment interventions, as well as providing a wealth of relevant epidemiological data. With 27 vaccines currently undergoing human trials, and countries worldwide continuing to battle case numbers, or prepare for resurgences, the need for efficient, high-quality pipelines for peer-reviewed research remains as crucial as ever.
Author: William B. Coleman
Publisher: Academic Press
ISBN: 0128229934
Category : Science
Languages : en
Pages : 846
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Book Description
Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing, Second Edition assembles a group of experts to discuss the molecular basis and mechanisms of major human diseases and disease processes and how the molecular features of disease can be harnessed to develop practical molecular tests for disease detection, diagnosis and prognosis. The book explains how molecular tests are utilized in the treatment of patients in personalized medicine, highlights new technologies and approaches of applied molecular pathology, and discusses how this discovery-based research yields new and useful biomarkers and tests. As it is essential to stay up-to-date on new molecular diagnostics in this changing field, this book covers critically important areas in the practice of personalized medicine and reflects our understanding of the pathology, pathogenesis and pathophysiology of human disease. - Includes new material on mass spectrometry for infectious diseases, microbiome, homology-directed repair for PARPi, whole genome sequencing for constitutional testing, and much more - Provides insights on the value of the molecular test in comparison to traditional methods, which include speed, precision, sensitivity and clinical impacts for the patient - Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis and classification in the clinical workup of a patient - Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for the prognostication of disease
Author: Jeff M. P. Holly
Publisher: Frontiers Media SA
ISBN: 283254259X
Category : Science
Languages : en
Pages : 178
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Book Description
Author: Ali Gholamrezanezhad
Publisher: John Wiley & Sons
ISBN: 1119789680
Category : Medical
Languages : en
Pages : 709
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Book Description
CORONAVIRUS DISEASE 2019 (COVID-19) CORONAVIRUS DISEASE 2019 (COVID-19) Provides comprehensive coverage of all key aspects of COVID-19, including: etiology, diagnosis, symptomatology, management, and treatment Coronavirus Disease 2019 (COVID-19): A Clinical Guide provides healthcare professionals at all levels with up-to-date knowledge about the clinical, epidemiological, genomic, virological, and radiologic features of COVID-19. Consolidating multiple systematic reviews and meta-analyses into a single volume, this comprehensive textbook also addresses health policies, mass casualty planning, healthcare worker safety, economic impact, lessons for future outbreaks, and other para-clinical and social aspects of the COVID-19 pandemic. The text presents a thorough summary and critical analysis of COVID-19 based on an exhaustive review of recently published literature and data. Topics include the virologic characteristics of SARS-CoV-2, pulmonary and extrapulmonary manifestations and consequences of COVID-19, prevention and transmission control, the pandemic’s indirect impact to the care and management of other diseases, passive immunotherapy and its implications, diagnostic and treatment approaches for critically ill patients, and more. Edited by leading practitioners at the forefront of COVID-19 research, this invaluable resource: Integrates clinical, radiological, and epidemiological data and discussion of prevention, diagnosis, and treatment Reviews the epidemiology, mechanisms of action, manifestations, and management of cardiovascular, neurological, and pulmonary diseases associated with COVID-19 Covers diagnostic technologies, includes radiologic imaging, and RT-PCR testing Explores therapeutic approaches for managing a variety of complications Discusses post-vaccination symptom management and implications of immunization Addresses COVID-19 in pediatrics, in cancer patients, and in patients with lung disease, diabetes, hypertension, obesity, and other underlying conditions Coronavirus Disease 2019 (COVID-19): A Clinical Guide is an indispensable source of information for all clinicians, researchers, epidemiologists, nurses, radiologists, and healthcare managers working to address any aspect of the COVID-19 pandemic.
Author: Marc Jean Struelens
Publisher: Frontiers Media SA
ISBN: 2832504973
Category : Medical
Languages : en
Pages : 863
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Book Description
