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Author: Robert Lindsay
Publisher: Springer Science & Business Media
ISBN: 146840766X
Category : Medical
Languages : en
Pages : 224
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Book Description
It seems particularly appropriate that this pioneering collection of papers should be dedicated to Donald Sholl since those of us who count, measure, and reconstruct elements of the neural en~emble are all very much in his debt. Sholl was certainly not the first to attempt quantification of certain aspects of brain structure. No computers were available to him for the kind of answers he sought, and some of his answers - or rather his interpretations - may not stand the test of time. But we remember him because of the questions he asked and for the reasons he asked them. At a time when the entire family of Golgi techniques was in almost total eclipse, he had the judgment to rely on them. And in a period when the canonical neuron was a perfect sphere (the enormous dendritic superstructure being almost forgotten), he was one of a very few who looked to dendrite extension and pattern as a prime clue to the overall problem of neuronal connectivity.
Author: Robert Lindsay
Publisher: Springer Science & Business Media
ISBN: 146840766X
Category : Medical
Languages : en
Pages : 224
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Book Description
It seems particularly appropriate that this pioneering collection of papers should be dedicated to Donald Sholl since those of us who count, measure, and reconstruct elements of the neural en~emble are all very much in his debt. Sholl was certainly not the first to attempt quantification of certain aspects of brain structure. No computers were available to him for the kind of answers he sought, and some of his answers - or rather his interpretations - may not stand the test of time. But we remember him because of the questions he asked and for the reasons he asked them. At a time when the entire family of Golgi techniques was in almost total eclipse, he had the judgment to rely on them. And in a period when the canonical neuron was a perfect sphere (the enormous dendritic superstructure being almost forgotten), he was one of a very few who looked to dendrite extension and pattern as a prime clue to the overall problem of neuronal connectivity.
Author: Giorgio A. Ascoli
Publisher: Springer Science & Business Media
ISBN: 1592592759
Category : Medical
Languages : en
Pages : 466
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Book Description
In Computational Neuroanatomy: Principles and Methods, the path-breaking investigators who founded the field review the principles and key techniques available to begin the creation of anatomically accurate and complete models of the brain. Combining the vast, data-rich field of anatomy with the computational power of novel hardware, software, and computer graphics, these pioneering investigators lead the reader from the subcellular details of dendritic branching and firing to system-level assemblies and models.
Author: Hermann Cuntz
Publisher: Springer Science & Business Media
ISBN: 1461480949
Category : Medical
Languages : en
Pages : 519
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Book Description
Neuronal dendritic trees are complex structures that endow the cell with powerful computing capabilities and allow for high neural interconnectivity. Studying the function of dendritic structures has a long tradition in theoretical neuroscience, starting with the pioneering work by Wilfrid Rall in the 1950s. Recent advances in experimental techniques allow us to study dendrites with a new perspective and in greater detail. The goal of this volume is to provide a résumé of the state-of-the-art in experimental, computational, and mathematical investigations into the functions of dendrites in a variety of neural systems. The book first looks at morphological properties of dendrites and summarizes the approaches to measure dendrite morphology quantitatively and to actually generate synthetic dendrite morphologies in computer models. This morphological characterization ranges from the study of fractal principles to describe dendrite topologies, to the consequences of optimization principles for dendrite shape. Individual approaches are collected to study the aspects of dendrite shape that relate directly to underlying circuit constraints and computation. The second main theme focuses on how dendrites contribute to the computations that neurons perform. What role do dendritic morphology and the distributions of synapses and membrane properties over the dendritic tree have in determining the output of a neuron in response to its input? A wide range of studies is brought together, with topics ranging from general to system-specific phenomena—some having a strong experimental component, and others being fully theoretical. The studies come from many different neural systems and animal species ranging from invertebrates to mammals. With this broad focus, an overview is given of the diversity of mechanisms that dendrites can employ to shape neural computations.
Author: J.J. Capowski
Publisher: Springer Science & Business Media
ISBN: 1468456911
Category : Science
Languages : en
Pages : 497
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Book Description
This book is the story of the marriage of a new techl}ology, computers, with an old problem, the study of neuroanatomical structures using the light microscope. It is aimed toward you, the neuroanatomist, who until now have used computers primarily for word processing but now wish to use them also to collect and analyze your laboratory data. Mter reading the book, you will be better equipped to use a computer system for data collection and analysis, to employ a programmer who might develop a system for you, or to evaluate the systems available in the marketplace. To start toward this goal, a glossary first presents commonly used terms in computer assisted neuroanatomy. This, on its own, will aid you as it merges the jargon of the two different fields. Then, Chapter 1 presents a historical review to describe the manual tasks involved in presenting and measuring anatomic structures. This review lays a base line of the tasks that were done before computers and the amount of skill and time needed to perform the tasks. In Chapters 2 and 3, you will find basic information about laboratory computers and programs to the depth required for you to use the machines easily and talk with some fluency to computer engineers, programmers, and salesmen. Chapters 4, 5, and 6 present the use of computers to reconstruct anatomic structures, i.e., to enter them into a computer memory, where they are later displayed and analyzed.
Author: Stanley B. Kater
Publisher: Springer Science & Business Media
ISBN: 3642871232
Category : Science
Languages : en
Pages : 339
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Book Description
The purpose of this book is to provide basic reference material to facilitate the further development and application of the intracellular staining techniques which originated with the introduction of Procion dye as a neurocellular stain. We had sev eral specific objectives in compiling these chapters. First, we recognized that both the techniques and results of intracellular staining have been derived from a variety of preparations and published in diverse journals. Consequently, we tried to make this information more readily available by incorporating several reviews by original authors. This should provide the reader with a knowledge of the kinds of neurobiological prob lems for which intracellular staining has already been employed. A second objective was to facilitate extension of these methods to a wider variety of problems. To this end there are chapters dealing with Procion dye as a marker for ultrastructural investi gations, the use of cobalt as a staining compound and the implementation of computer techniques for quantitative studies of neuronal relationships. As background for further extension of these methods this volume contains material on the history of the discovery of Procion dyes as intracellular stains, the chemistry of these dyes, and fundamentals of fluorescence microscopy. Our final specific objective was to present details of technical procedures that were not readily available in the literature.
Author:
Publisher: Academic Press
ISBN: 0080586279
Category : Science
Languages : en
Pages : 397
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Book Description
International Review of Cytology presents current advances and comprehensive reviews in cell biology – both plant and animal. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
Author: National Institutes of Health (U.S.). Division of Research Grants
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1224
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Book Description
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Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 874
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Book Description
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Publisher:
ISBN:
Category : Neurology
Languages : en
Pages : 1214
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Book Description
Author:
Publisher: National Academies
ISBN:
Category : Labyrinth (Ear)
Languages : en
Pages : 400
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Book Description
