Author: Satyajit Dey Sarker
Publisher: Elsevier
ISBN: 0443161038
Category : Science
Languages : en
Pages : 532
Get Book Here
Book Description
Computational Phytochemistry, Second Edition, explores how recent advances in computational techniques and methods have been embraced by phytochemical researchers to enhance many of their operations, refocusing and expanding the possibilities of phytochemical studies. By applying computational aids and mathematical models to extraction, isolation, structure determination, and bioactivity testing, researchers can obtain highly detailed information about phytochemicals and optimize working approaches. This book aims to support and encourage researchers currently working with or looking to incorporate computational methods into their phytochemical work. Topics in this book include computational methods for predicting medicinal properties, optimizing extraction, isolating plant secondary metabolites, and building dereplicated phytochemical libraries. The roles of high-throughput screening, spectral data for structural prediction, plant metabolomics, and biosynthesis are all reviewed before the application of computational aids for assessing bioactivities and virtual screening is discussed. Illustrated with detailed figures and supported by practical examples, this book is an indispensable guide for all those involved with the identification, extraction, and application of active agents from natural products. This new edition captures remarkable advancements in mathematical modeling and computational methods that have been incorporated in phytochemical research, addressing, e.g., extraction, isolation, structure determination, and bioactivity testing of phytochemicals. - Includes step-by-step protocols for various computational and mathematical approaches applied to phytochemical research - Features clearly illustrated chapters contributed by highly reputable researchers - Covers all key areas in phytochemical research, including virtual screening and metabolomics
Author: Chukwuebuka Egbuna
Publisher: CRC Press
ISBN: 0429760329
Category : Health & Fitness
Languages : en
Pages : 615
Get Book Here
Book Description
This first book in this three-volume set provides comprehensive coverage of a wide range of topics in phytochemistry. With chapters from professional specialists from key institutions around the world, the volume starts with an introduction to phytochemistry and details the fundamentals. Part II discusses the state-of-the-art modern methods and techniques in phytochemical research, while Part III provides an informative overview of computational phytochemistry and its applications. Part IV presents novel research findings in the discovery of drugs that will be effective in the treatment of diseases. The chapters are drawn carefully and integrated sequentially to aid flow, consistency, and continuity.
Author: Mohd Adnan
Publisher: CRC Press
ISBN: 1000923142
Category : Science
Languages : en
Pages : 668
Get Book Here
Book Description
Medicinal and aromatic plants are beneficial to human health. Plant-derived molecules possess biological activities that can be used to prevent many infectious diseases and metabolic disorders. Ethnobotany and Ethnopharmacology of Medicinal and Aromatic Plants summarizes techniques and methods used to study the biological activities of plant-derived extracts and compounds to study ethnobotanical and ethnopharmacological features of medicinal and aromatic plants. This book: Includes computational approaches to study the pharmacological properties of biomolecules in medicinal and aromatic plants. Details methods in ethnopharmacology including chromatographical and analytical techniques. Demonstrates trends in sustainable use and management of medicinal and aromatic plants. Features information on databases and tools used in computational phytochemistry for drug designing and discovery. Elucidates the importance of phytochemicals as immunomodulators in herbal drug development including their nanoformulations. A volume in the Exploring Medicinal Plants series, Ethnobotany and Ethnopharmacology of Medicinal and Aromatic Plants will be of interest to those working with plant extracts, including botanists and ethnobotanists, pharmacologists and ethnopharmacologists, as well as scientists and researchers interested in natural compounds and their potential applications.
Author: Pradeep Kumar Mallick
Publisher: Springer Nature
ISBN: 9811570310
Category : Technology & Engineering
Languages : en
Pages : 1126
Get Book Here
Book Description
This book presents selected, high-quality research papers from the International Conference on Electronic Systems and Intelligent Computing (ESIC 2020), held at NIT Yupia, Arunachal Pradesh, India, on 2 – 4 March 2020. Discussing the latest challenges and solutions in the field of smart computing, cyber-physical systems and intelligent technologies, it includes papers based on original theoretical, practical and experimental simulations, developments, applications, measurements, and testing. The applications and solutions featured provide valuable reference material for future product development.
Author: Sreeraj Gopi
Publisher: CRC Press
ISBN: 1000353613
Category : Science
Languages : en
Pages : 240
Get Book Here
Book Description
This new volume provides a bird’s-eye view of the properties, utilization, and importance of high resolution mass spectrometry (HRMS) for phytochemical analysis. The book discusses the new and state-of-the-art technologies related to HRMS in phytochemical analysis for the food industry in a comprehensive manner. Phytochemical characterization of plants is important in the food and nutraceutical industries and is also necessary in the procedures followed for drug development, toxicology determination, forensic studies, origin verification, quality assurance, etc. Easy determination of active compounds and isolation as well as purification of the same from natural matrices are required, and the possibilities and advantages of HRMS pave the way for improved analysis patterns in phytochemistry. This book is unique in that its sole consideration is on the importance of HRMS in the field of phytochemical analysis. Along with an overview of basic instrumental information, the volume provides a detailed account of data processing and dereplication strategies. Technologies such as bioanalytical techniques and bioassays are considered also to provide support for the functions of the instruments used. In addition, a case study is presented to depict the complete phytochemical characterization of a matrix by HRMS. The book covers processing and computational techniques, dereplication, hyphenation, high-resolution bioassays, bioanalytical screening/purification techniques, applications of gas chromatography–high-resolution mass spectrometry, and more. Key features: Covers the fundamental instrumentation and techniques Discusses HRMS-based phytochemical research details Focuses strictly on the phytochemical considerations High-Resolution Mass Spectroscopy for Phytochemical Analysis: State-of-the-Art Applications and Techniques will be a valuable reference guide and resource for researchers, faculty and students in related fields, as well as those in the phytochemical industries.
Author: Carrillo-Cedillo, Eugenia Gabriela
Publisher: IGI Global
ISBN: 179981520X
Category : Science
Languages : en
Pages : 429
Get Book Here
Book Description
Statistics is a key characteristic that assists a wide variety of professions including business, government, and factual sciences. Companies need data calculation to make informed decisions that help maintain their relevance. Design of experiments (DOE) is a set of active techniques that provides a more efficient approach for industries to test their processes and form effective conclusions. Experimental design can be implemented into multiple professions, and it is a necessity to promote applicable research on this up-and-coming method. Design of Experiments for Chemical, Pharmaceutical, Food, and Industrial Applications is a pivotal reference source that seeks to increase the use of design of experiments to optimize and improve analytical methods and productive processes in order to use less resources and time. While highlighting topics such as multivariate methods, factorial experiments, and pharmaceutical research, this publication is ideally designed for industrial designers, research scientists, chemical engineers, managers, academicians, and students seeking current research on advanced and multivariate statistics.
Author: Jorddy Neves Cruz
Publisher: Springer Nature
ISBN: 303135205X
Category : Medical
Languages : en
Pages : 541
Get Book Here
Book Description
Historically, natural products have great relevance for the development of new drugs. Natural molecules, in addition to directly providing new compounds with different therapeutic functions have provided scaffolds and a great diversity of structures that serve as inspiration for the design and discovery of new drugs. The great structural complexity and the significant number of natural compounds that can be obtained and their advantages also present some historical problems that need to be overcome. Issues such as difficulty in isolation, difficulty in synthesizing compounds found in nature in the laboratory, screening to evaluate the biological properties of these compounds, and structural optimization to enhance the pharmacological properties of biomolecules; are some of the main difficulties encountered in research with natural products and in the design/discovery of new medicines. Therefore, this book addresses the great scientific advances that provide practical solutions to using natural products to develop new drugs. We address topics related to the genesis of research projects that use natural products to design new drugs. We address the discovery of new species, initial processes for identification and extraction of compounds, isolation and identification of these structures, techniques, and advances in vitro and in vivo methods that support the discovery of new natural drugs, synthesis of new compounds from natural molecules, in silico optimization processes of potentially promising compounds.
Author: Jen-Tsung Chen
Publisher: CRC Press
ISBN: 1000909093
Category : Medical
Languages : en
Pages : 681
Get Book Here
Book Description
Coronaviruses can cause illness, severe disease, and death; for example, Middle East respiratory syndrome (MERS), severe acute respiratory syndrome (SARS), and COVID-19. Vaccine development and antiviral drugs are challenged by the propensity for viral mutations allowing these viruses to evade such therapies. There are a number of bioactive compounds from natural sources, which can exert health benefits and act as antiviral therapies such as anti-inflammation, antioxidative stress, and immune regulation. This book summarizes research on the potential efficacy and underlying mechanisms of bioactive compounds and traditional medicines against SARS-CoV-2. Key Features Summarizes the potential benefits of bioactive therapies for coronaviruses Focuses on COVID-19, but also covers MERS and SARS Provides alternatives to vaccines and other antiviral drugs whose efficacy is reduced by viral mutations Relevant for clinicians and public health officials
Author: Mihir Kumar Purkait
Publisher: Elsevier
ISBN: 0443185360
Category : Medical
Languages : en
Pages : 286
Get Book Here
Book Description
Advances in Extraction and Applications of Bioactive Phytochemicals presents comprehensive and systematic coverage of extraction techniques for bioactive phytochemical compounds and their delivery and therapeutic effectiveness. Sections focus on the pharmaceutical industry's perspective, aiming at compiling recent advances of natural products in the field of drug delivery, including a brief overview of plant-based bioactive molecules, utilization of different plant elements for the extraction of phytochemicals, a compilation of conventional extraction approaches, advanced extraction methods, including Supercritical carbon-dioxide extraction, computational methods to improve production, drug delivery aspects of bioactive phytochemicals, their therapeutic effectiveness, and more. This book is a complete reference targeted at pharma researchers in academic and corporate environments and those willing to apply the most current extraction methods and health applications. Researchers in medicinal chemistry and chemical engineering will also benefit from this comprehensive resource. - Offers a consistent compilation of the most current phytochemical extraction techniques - Includes detailed protocols for extraction - Covers the main classes of naturally occurring bioactive phytochemical compounds
Author: Abdalbasit Adam Mariod
Publisher: Academic Press
ISBN: 0323903266
Category : Technology & Engineering
Languages : en
Pages : 454
Get Book Here
Book Description
Multiple Biological Activities of Unconventional Seed Oils brings detailed knowledge concerning the biological properties of oils (antioxidant, antimicrobial, antidiabetic, antitumor, anti-inflammatory, etc.), the content of individual substances with health-promoting properties, methods for biological properties assay, the influence of raw material quality and technological processes on the quality of oils, and possible raw materials and oil contaminants with adverse health effects. The book's chapters also highlight the unique properties of new oils, along with their biological activities. Less than a decade ago, the vegetable oils on grocery store shelves were derived from conventional oil seeds e.g., cotton, groundnut, sesame, corn sunflower and soybean. However, as consumers began to understand how fat intake affects overall health, researchers, plant growers and food manufacturers started to produce oils from unconventional sources. This book highlights what we've learned in the process. - Explores unconventional oils, their different sources, and where they grow worldwide - Explains the medicinal uses of unconventional oils - Details the biological activities, antioxidant and physico-chemical composition of unconventional oils
