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Author: Adam Wittek
Publisher: Springer Nature
ISBN: 3031646320
Category :
Languages : en
Pages : 174
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Book Description
Author: Adam Wittek
Publisher: Springer Nature
ISBN: 3031646320
Category :
Languages : en
Pages : 174
Get Book Here
Book Description
Author: Zlatko Trajanoski
Publisher: Springer Science & Business Media
ISBN: 3709109477
Category : Science
Languages : en
Pages : 207
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Book Description
Computational methodologies and modeling play a growing role for investigating mechanisms, and for the diagnosis and therapy of human diseases. This progress gave rise to computational medicine, an interdisciplinary field at the interface of computer science and medicine. The main focus of computational medicine lies in the development of data analysis methods and mathematical modeling as well as computational simulation techniques specifically addressing medical problems. In this book, we present a number of computational medicine topics at several scales: from molecules to cells, organs, and organisms. At the molecular level, tools for the analysis of genome variations as well as cloud computing resources for medical genetics are reviewed. Then, an analysis of gene expression data and the application to the characterization of microbial communities are highlighted. At the protein level, two types of analyses for mass spectrometry data are reviewed: labeled quantitative proteomics and lipidomics, followed by protein sequence analysis and a 3D structure and drug design chapter. Finally, three chapters on clinical applications focus on the integration of biomolecular and clinical data for cancer research, biomarker discovery, and network-based methods for computational diagnostics.
Author: Goran Rakocevic
Publisher: Springer Science & Business Media
ISBN: 1461487854
Category : Computers
Languages : en
Pages : 383
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Book Description
This book presents an overview of a variety of contemporary statistical, mathematical and computer science techniques which are used to further the knowledge in the medical domain. The authors focus on applying data mining to the medical domain, including mining the sets of clinical data typically found in patient’s medical records, image mining, medical mining, data mining and machine learning applied to generic genomic data and more. This work also introduces modeling behavior of cancer cells, multi-scale computational models and simulations of blood flow through vessels by using patient-specific models. The authors cover different imaging techniques used to generate patient-specific models. This is used in computational fluid dynamics software to analyze fluid flow. Case studies are provided at the end of each chapter. Professionals and researchers with quantitative backgrounds will find Computational Medicine in Data Mining and Modeling useful as a reference. Advanced-level students studying computer science, mathematics, statistics and biomedicine will also find this book valuable as a reference or secondary text book.
Author: Diana J Vincent
Publisher: World Scientific
ISBN: 9814548332
Category :
Languages : en
Pages : 1630
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Book Description
This three volume series represents a selected and refereed collection of papers contributed by the participants of the First World Congress on Computational Medicine, Public Health, and Biotechnology, held in 1994 at Austin, Texas. Over 500 individuals, from 30 countries attended this meeting. In addition, this collection contains a number of papers from the Australian CSIRO High Performance Computing Meeting held that same year.
Author: D. C. Young
Publisher: John Wiley & Sons
ISBN: 9780470451847
Category : Science
Languages : en
Pages : 344
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Book Description
Helps you choose the right computational tools and techniques to meet your drug design goals Computational Drug Design covers all of the major computational drug design techniques in use today, focusing on the process that pharmaceutical chemists employ to design a new drug molecule. The discussions of which computational tools to use and when and how to use them are all based on typical pharmaceutical industry drug design processes. Following an introduction, the book is divided into three parts: Part One, The Drug Design Process, sets forth a variety of design processes suitable for a number of different drug development scenarios and drug targets. The author demonstrates how computational techniques are typically used during the design process, helping readers choose the best computational tools to meet their goals. Part Two, Computational Tools and Techniques, offers a series of chapters, each one dedicated to a single computational technique. Readers discover the strengths and weaknesses of each technique. Moreover, the book tabulates comparative accuracy studies, giving readers an unbiased comparison of all the available techniques. Part Three, Related Topics, addresses new, emerging, and complementary technologies, including bioinformatics, simulations at the cellular and organ level, synthesis route prediction, proteomics, and prodrug approaches. The book's accompanying CD-ROM, a special feature, offers graphics of the molecular structures and dynamic reactions discussed in the book as well as demos from computational drug design software companies. Computational Drug Design is ideal for both students and professionals in drug design, helping them choose and take full advantage of the best computational tools available. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.
Author: Peter Coveney
Publisher: Oxford University Press, USA
ISBN: 0199658188
Category : Computers
Languages : en
Pages : 294
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Book Description
Computational Biomedicine unifies the different strands of a broad-ranging subject to demonstrate the power of a tool that has the potential to revolutionise our understanding of the human body, and the therapeutic strategies available to maintain and protect it.
Author: Kenneth W. Goodman
Publisher: Cambridge University Press
ISBN: 9780521469050
Category : Computers
Languages : en
Pages : 196
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Book Description
New technology always raises compelling ethical questions. As those in medicine increasingly depend on computers and other intelligent machines, the intersection of ethics, computing and the health professions grows much more complex and significant. This book attempts systematically to identify and address the full range of ethical issues that arise when intelligent machines are used in medicine, nursing, psychology, and allied health professions. It maps and explores a variety of important issues and controversies, including ethics and evaluation in computational medicine, patient and provider confidentiality, responsibility for use of computers in medicine, appropriate use of decision support systems, outcomes of research and computational prognosis (including mortality predictions), and computer-based biomedical research - especially meta-analysis. This book is accessible to participants in the fields of bioethics and medical informatics. It is appropriate for physicians, nurses, administrators, ethicists, health attorneys, advanced undergraduates and graduate students.
Author: Moo K. Chung
Publisher: World Scientific
ISBN: 9814335436
Category : Computers
Languages : en
Pages : 424
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Book Description
Computational neuroanatomy is an emerging field that utilizes various non-invasive brain imaging modalities, such as MRI and DTI, in quantifying the spatiotemporal dynamics of the human brain structures in both normal and clinical populations. This discipline emerged about twenty years ago and has made substantial progress in the past decade. The main goals of this book are to provide an overview of various mathematical, statistical and computational methodologies used in the field to a wide range of researchers and students, and to address important yet technically challenging topics in further detail.
Author: Ivo Babuska
Publisher: Springer Science & Business Media
ISBN: 1461242487
Category : Mathematics
Languages : en
Pages : 487
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Book Description
With considerations such as complex-dimensional geometries and nonlinearity, the computational solution of partial differential systems has become so involved that it is important to automate decisions that have been normally left to the individual. This book covers such decisions: 1) mesh generation with links to the software generating the domain geometry, 2) solution accuracy and reliability with mesh selection linked to solution generation. This book is suited for mathematicians, computer scientists and engineers and is intended to encourage interdisciplinary interaction between the diverse groups.
Author: Barry Doyle
Publisher: Springer
ISBN: 149390745X
Category : Technology & Engineering
Languages : en
Pages : 128
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Book Description
One of the greatest challenges facing the computational engineering community is to extend the success of computational mechanics to fields outside traditional engineering, in particular to biology, the biomedical sciences and medicine. The Computational Biomechanics for Medicine series provides an opportunity for specialists in computational biomechanics to present their latest methodologies and advancements. This 5th edition comprises nine of the latest developments in both fundamental science and patient-specific applications, from researchers in Australia, New Zealand, USA, UK, France, Ireland and China. Some of the interesting topics discussed are: cellular mechanics; tumor growth and modeling; medical image analysis and both patient-specific fluid dynamics and solid mechanic simulations.
