Computational analysis of promoters in prokaryotic genomes

Computational analysis of promoters in prokaryotic genomes PDF Author:
Publisher: Frontiers Media SA
ISBN: 2832530656
Category : Science
Languages : en
Pages : 96

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Book Description

Computational analysis of promoters in prokaryotic genomes

Computational analysis of promoters in prokaryotic genomes PDF Author:
Publisher: Frontiers Media SA
ISBN: 2832530656
Category : Science
Languages : en
Pages : 96

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Book Description


Computational Methods for Understanding Bacterial and Archaeal Genomes

Computational Methods for Understanding Bacterial and Archaeal Genomes PDF Author: Ying Xu
Publisher: World Scientific
ISBN: 1860949827
Category : Medical
Languages : en
Pages : 494

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Book Description
Over 500 prokaryotic genomes have been sequenced to date, and thousands more have been planned for the next few years. While these genomic sequence data provide unprecedented opportunities for biologists to study the world of prokaryotes, they also raise extremely challenging issues such as how to decode the rich information encoded in these genomes. This comprehensive volume includes a collection of cohesively written chapters on prokaryotic genomes, their organization and evolution, the information they encode, and the computational approaches needed to derive such information. A comparative view of bacterial and archaeal genomes, and how information is encoded differently in them, is also presented. Combining theoretical discussions and computational techniques, the book serves as a valuable introductory textbook for graduate-level microbial genomics and informatics courses.

Plant Genomes

Plant Genomes PDF Author: Jean-Nicolas Volff
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805584911
Category : Medical
Languages : en
Pages : 155

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Book Description
Recent major advances in the field of comparative genomics and cytogenomics of plants, particularly associated with the completion of ambitious genome projects, have uncovered astonishing facets of the architecture and evolutionary history of plant genomes. The aim of this book was to review these recent developments as well as their implications in our understanding of the mechanisms which drive plant diversity. New insights into the evolution of gene functions, gene families and genome size are presented, with particular emphasis on the evolutionary impact of polyploidization and transposable elements. Knowledge on the structure and evolution of plant sex chromosomes, centromeres and microRNAs is reviewed and updated. Taken together, the contributions by internationally recognized experts present a panoramic overview of the structural features and evolutionary dynamics of plant genomes.This volume of Genome Dynamics will provide researchers, teachers and students in the fields of biology and agronomy with a valuable source of current knowledge on plant genomes.

Metagenomics and Its Applications in Agriculture, Biomedicine and Environmental Studies

Metagenomics and Its Applications in Agriculture, Biomedicine and Environmental Studies PDF Author: Robert W. Li
Publisher: Nova Science Publishers
ISBN: 9781628086447
Category : Microbial ecology
Languages : en
Pages : 0

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Book Description
Metagenomics is the study of microbial communities sampled directly from their natural environment, without prior culturing. DNA sequencing (or alternatively, an assay of functional properties) is applied to the culture-independent analyses of complex and diverse ("meta") populations of microbes. The rapid growth of metagenomics entails an expanded focus on microbes in a wide range of basic and applied research fields, ranging from microbiology to agriculture, biomedicine to bioenergy, and from veterinary to clinical medicine. This book is an insightful and inclusive study on metagenomics and its applications.

Gene Regulation and Metabolism

Gene Regulation and Metabolism PDF Author: Julio Collado-Vides
Publisher: MIT Press
ISBN: 9780262532686
Category : Computers
Languages : en
Pages : 326

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Book Description
An overview of current computational approaches to metabolism and gene regulation.

Sequence — Evolution — Function

Sequence — Evolution — Function PDF Author: Eugene V. Koonin
Publisher: Springer Science & Business Media
ISBN: 1475737831
Category : Science
Languages : en
Pages : 482

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Book Description
Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.

A Handbook of Transcription Factors

A Handbook of Transcription Factors PDF Author: Timothy R. Hughes
Publisher: Springer Science & Business Media
ISBN: 904819069X
Category : Medical
Languages : en
Pages : 310

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Book Description
Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.

Text Algorithms

Text Algorithms PDF Author: Maxime Crochemore
Publisher: Maxime Crochemore
ISBN: 0195086090
Category : Algorithms
Languages : en
Pages : 396

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Book Description
This much-needed book on the design of algorithms and data structures for text processing emphasizes both theoretical foundations and practical applications. It is intended to serve both as a textbook for courses on algorithm design, especially those related to text processing, and as a reference for computer science professionals. The work takes a unique approach, one that goes more deeply into its topic than other more general books. It contains both classical algorithms and recent results of research on the subject. The book is the first text to contain a collection of a wide range of text algorithms, many of them quite new and appearing here for the first time. Other algorithms, while known by reputation, have never been published in the journal literature. Two such important algorithms are those of Karp, Miller and Rosenberg, and that of Weiner. Here they are presented together for the fist time. The core of the book is the material on suffix trees and subword graphs, applications of these data structures, new approaches to time-space optimal string-matching, and text compression. Also covered are basic parallel algorithms for text problems. Applications of all these algorithms are given for problems involving data retrieval systems, treatment of natural languages, investigation of genomes, data compression software, and text processing tools. From the theoretical point of view. the book is a goldmine of paradigms for the development of efficient algorithms, providing the necessary foundation to creating practical software dealing with sequences. A crucial point in the authors' approach is the development of a methodology for presenting text algorithms so they can be fully understood. Throughout, the book emphasizes the efficiency of algorithms, holding that the essence of their usefulness depends on it. This is especially important since the algorithms described here will find application in "Big Science" areas like molecular sequence analysis where the explosive growth of data has caused problems for the current generation of software. Finally, with its development of theoretical background, the book can be considered as a mathematical foundation for the analysis and production of text processing algorithms.

Equilibrium Statistical Physics

Equilibrium Statistical Physics PDF Author: Michael Plischke
Publisher: World Scientific
ISBN: 9789810216429
Category : Science
Languages : en
Pages : 540

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Book Description
This textbook concentrates on modern topics in statistical physics with an emphasis on strongly interacting condensed matter systems. The book is self-contained and is suitable for beginning graduate students in physics and materials science or undergraduates who have taken an introductory course in statistical mechanics. Phase transitions and critical phenomena are discussed in detail including mean field and Landau theories and the renormalization group approach. The theories are applied to a number of interesting systems such as magnets, liquid crystals, polymers, membranes, interacting Bose and Fermi fluids; disordered systems, percolation and spin of equilibrium concepts are also discussed. Computer simulations of condensed matter systems by Monte Carlo-based and molecular dynamics methods are treated.

The Pangenome

The Pangenome PDF Author: Hervé Tettelin
Publisher: Springer Nature
ISBN: 3030382818
Category : Science
Languages : en
Pages : 311

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Book Description
This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book’s respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.