Computation in Cells and Tissues

Computation in Cells and Tissues PDF Author: R. Paton
Publisher: Springer Science & Business Media
ISBN: 3662063697
Category : Computers
Languages : en
Pages : 349

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Book Description
The field of biologically inspired computation has coexisted with mainstream computing since the 1930s, and the pioneers in this area include Warren McCulloch, Walter Pitts, Robert Rosen, Otto Schmitt, Alan Turing, John von Neumann and Norbert Wiener. Ideas arising out of studies of biology have permeated algorithmics, automata theory, artificial intelligence, graphics, information systems and software design. Within this context, the biomolecular, cellular and tissue levels of biological organisation have had a considerable inspirational impact on the development of computational ideas. Such innovations include neural computing, systolic arrays, genetic and immune algorithms, cellular automata, artificial tissues, DNA computing and protein memories. With the rapid growth in biological knowledge there remains a vast source of ideas yet to be tapped. This includes developments associated with biomolecular, genomic, enzymic, metabolic, signalling and developmental systems and the various impacts on distributed, adaptive, hybrid and emergent computation. This multidisciplinary book brings together a collection of chapters by biologists, computer scientists, engineers and mathematicians who were drawn together to examine the ways in which the interdisciplinary displacement of concepts and ideas could develop new insights into emerging computing paradigms. Funded by the UK Engineering and Physical Sciences Research Council (EPSRC), the CytoCom Network formally met on five occasions to examine and discuss common issues in biology and computing that could be exploited to develop emerging models of computation.

Computation in Cells and Tissues

Computation in Cells and Tissues PDF Author: R. Paton
Publisher: Springer Science & Business Media
ISBN: 3662063697
Category : Computers
Languages : en
Pages : 349

Get Book Here

Book Description
The field of biologically inspired computation has coexisted with mainstream computing since the 1930s, and the pioneers in this area include Warren McCulloch, Walter Pitts, Robert Rosen, Otto Schmitt, Alan Turing, John von Neumann and Norbert Wiener. Ideas arising out of studies of biology have permeated algorithmics, automata theory, artificial intelligence, graphics, information systems and software design. Within this context, the biomolecular, cellular and tissue levels of biological organisation have had a considerable inspirational impact on the development of computational ideas. Such innovations include neural computing, systolic arrays, genetic and immune algorithms, cellular automata, artificial tissues, DNA computing and protein memories. With the rapid growth in biological knowledge there remains a vast source of ideas yet to be tapped. This includes developments associated with biomolecular, genomic, enzymic, metabolic, signalling and developmental systems and the various impacts on distributed, adaptive, hybrid and emergent computation. This multidisciplinary book brings together a collection of chapters by biologists, computer scientists, engineers and mathematicians who were drawn together to examine the ways in which the interdisciplinary displacement of concepts and ideas could develop new insights into emerging computing paradigms. Funded by the UK Engineering and Physical Sciences Research Council (EPSRC), the CytoCom Network formally met on five occasions to examine and discuss common issues in biology and computing that could be exploited to develop emerging models of computation.

Computational Modeling in Tissue Engineering

Computational Modeling in Tissue Engineering PDF Author: Liesbet Geris
Publisher: Springer Science & Business Media
ISBN: 3642325637
Category : Technology & Engineering
Languages : en
Pages : 438

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Book Description
One of the major challenges in tissue engineering is the translation of biological knowledge on complex cell and tissue behavior into a predictive and robust engineering process. Mastering this complexity is an essential step towards clinical applications of tissue engineering. This volume discusses computational modeling tools that allow studying the biological complexity in a more quantitative way. More specifically, computational tools can help in: (i) quantifying and optimizing the tissue engineering product, e.g. by adapting scaffold design to optimize micro-environmental signals or by adapting selection criteria to improve homogeneity of the selected cell population; (ii) quantifying and optimizing the tissue engineering process, e.g. by adapting bioreactor design to improve quality and quantity of the final product; and (iii) assessing the influence of the in vivo environment on the behavior of the tissue engineering product, e.g. by investigating vascular ingrowth. The book presents examples of each of the above mentioned areas of computational modeling. The underlying tissue engineering applications will vary from blood vessels over trachea to cartilage and bone. For the chapters describing examples of the first two areas, the main focus is on (the optimization of) mechanical signals, mass transport and fluid flow encountered by the cells in scaffolds and bioreactors as well as on the optimization of the cell population itself. In the chapters describing modeling contributions in the third area, the focus will shift towards the biology, the complex interactions between biology and the micro-environmental signals and the ways in which modeling might be able to assist in investigating and mastering this complexity. The chapters cover issues related to (multiscale/multiphysics) model building, training and validation, but also discuss recent advances in scientific computing techniques that are needed to implement these models as well as new tools that can be used to experimentally validate the computational results.

Computation in Cells and Tissues

Computation in Cells and Tissues PDF Author: R. Paton
Publisher:
ISBN: 9783662063705
Category :
Languages : en
Pages : 366

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Book Description


Computation in Cellular and Molecular Biological Systems

Computation in Cellular and Molecular Biological Systems PDF Author: Roy Cuthbertson
Publisher: World Scientific
ISBN: 9789810228781
Category : Science
Languages : en
Pages : 380

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Book Description
Computation in Cellular and Molecular Biological Systems is a selection of papers presented at the First International Workshop on Information Processing in Cells and Tissues (IPCAT 95). The book contains contributions from mathematicians, biochemists, cell biologists, physiologists and computer scientists. It is multidisciplinary in nature and deals with integrative aspects of information processing, cellular systems and dynamical methods.

Computational Cell Biology

Computational Cell Biology PDF Author: Christopher P. Fall
Publisher: Springer Science & Business Media
ISBN: 0387224599
Category : Science
Languages : en
Pages : 484

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Book Description
This textbook provides an introduction to dynamic modeling in molecular cell biology, taking a computational and intuitive approach. Detailed illustrations, examples, and exercises are included throughout the text. Appendices containing mathematical and computational techniques are provided as a reference tool.

Modeling Excitable Tissue

Modeling Excitable Tissue PDF Author: Aslak Tveito
Publisher: Springer Nature
ISBN: 3030611574
Category : Mathematics
Languages : en
Pages : 116

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Book Description
This open access volume presents a novel computational framework for understanding how collections of excitable cells work. The key approach in the text is to model excitable tissue by representing the individual cells constituting the tissue. This is in stark contrast to the common approach where homogenization is used to develop models where the cells are not explicitly present. The approach allows for very detailed analysis of small collections of excitable cells, but computational challenges limit the applicability in the presence of large collections of cells.

Information Processing in Cells and Tissues

Information Processing in Cells and Tissues PDF Author: Mike Holcombe
Publisher: Springer Science & Business Media
ISBN: 1461553458
Category : Medical
Languages : en
Pages : 325

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Book Description
Proceedings of an International Workshop held in Sheffield, UK, September 1-4, 1997

Information Processing in Cells and Tissues

Information Processing in Cells and Tissues PDF Author: Michael A. Lones
Publisher: Springer
ISBN: 3642287921
Category : Computers
Languages : en
Pages : 290

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Book Description
This book constitutes the refereed proceedings of the 9th International Conference on Information in Cells and Tissues, IPCAT 2012, held in Cambridge, UK, in March/April 2012. The 13 revised full papers presented together with 26 extended abstracts were carefully reviewed and selected from numerous submissions. The papers cover a wide range of topics in disciplines related to genetic and epigenetic networks, transcriptomics and gene regulation, signalling pathways and responses, protein structure and metabolic networks, patterning and rhythm generation, neural modelling and neural networks, biomedical modelling and signal processing, information processing and representation, and algorithmic approaches in computational biology.

Computational Methods for the Identification and Characterization of Tissues and Cells

Computational Methods for the Identification and Characterization of Tissues and Cells PDF Author: Khadija El Amrani
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Information Processing in Cells and Tissues

Information Processing in Cells and Tissues PDF Author: Michael Lones
Publisher: Springer
ISBN: 3319231081
Category : Computers
Languages : en
Pages : 232

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Book Description
This book constitutes the proceedings of the 10th International Conference on Information Processing in Cells and Tissues, IPCAT 2015, held in San Diego, CA, USA, in September 2015. The 19 papers presented in this volume were carefully reviewed and selected from 22 submissions. They were organized in topical sections named: biochemical information processing; collective and distributed behavior; patterning and rhythm generation; biochemical regulatory networks; metabolomics and phenotypes; and neural modelling and neural networks.