The Pathophysiology and Pharmacotherapy of Myocardial Infarction

The Pathophysiology and Pharmacotherapy of Myocardial Infarction PDF Author: Nabil El-Sherif
Publisher: Elsevier
ISBN: 1483277143
Category : Health & Fitness
Languages : en
Pages : 404

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Book Description
The Pathophysiology and Pharmacotherapy of Myocardial Infarction deals with the advances in the pathophysiology and pharmacotherapy of acute myocardial infarction and related complications. This book covers two major consequences—cardiac muscle dysfunction and cardiac electrical dysfunction. This text begins by reviewing the controversy surrounding the pathogenetic mechanisms of atheroma formation and its potential reversibility, including the status of coronary risk factors and benefits of primary prevention. The pathophysiologic mechanisms of pump failure and the current approach to its management are then deliberated, followed by a discussion on the rational use of vasodilators in post-infarction heart failure and pharmacotherapy of cardiogenic shock. The rationale for the interest in the role of coronary vasospasm and thrombolytic therapy for acute myocardial infarction is also covered. This publication concludes by reviewing the approaches for the management of post-infarction ventricular tachyarrhythmias and concept of secondary prevention of sudden cardiac death. This compilation is valuable to medical students, primary care physicians, and cardiovascular specialists.

Primary Angioplasty

Primary Angioplasty PDF Author: Timothy J Watson
Publisher: Springer
ISBN: 9811311145
Category : Medical
Languages : en
Pages : 339

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Book Description
This book is open access under a CC BY 4.0 license. This quick-reference handbook offers a concise and practical review of key aspects of the treatment of ST-segment elevation myocardial infarction (STEMI) in the era of primary percutaneous coronary intervention (PPCI). In the context of STEMI, PPCI is the preferred mode of emergency revascularization. Access to PPCI is rapidly increasing and is now routinely practiced in both general and specialist hospitals and there has been a recent emphasis on developing STEMI networks to enhance and expedite the referral pathway. This coupled with concurrent developments to enhance the safety and efficacy of the PPCI procedure has heralded an era where STEMI interventions are increasingly considered an important subspecialty within interventional cardiology. Written by leading cardiologists who have been instrumental in the adoption of PPCI in their respective institutions, the book provides junior and senior cardiologists alike with insightful and thought-provoking tips and tricks to enhance the success of PPCI procedures, which may in turn translate into direct improvements in outcomes. The book is also relevant for healthcare providers and emergency department physicians.

Bioresorbable Scaffolds

Bioresorbable Scaffolds PDF Author: Yoshinobu Onuma
Publisher: CRC Press
ISBN: 1498779778
Category : Medical
Languages : en
Pages : 552

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Book Description
This book focuses on the coronary bioresorbable scaffold, a new interventional treatment for coronary artery disease, differentiated from a permanent metallic stent. The book provides an overview of the technology including non-clinical studies and clinical evidences in order to help clinicians understand the appropriate application of the technology and the optimal techniques of implantation. It covers the basics of bioresorbable scaffolds; bench test results; preclinical studies; clinical evidences; and tips and tricks of implantation.

Acute Coronary Care

Acute Coronary Care PDF Author: Robert M. Califf
Publisher: Springer Science & Business Media
ISBN: 146133828X
Category : Medical
Languages : en
Pages : 536

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Book Description
When a patient develops symptoms suggestive of and infarction, this section is emphasized. There acute coronary insufficiency, the health care sys are brief sections on prediction and prevention of tem is presented with a challenging diagnostic ischemic events, methods of diagnosing and siz and management problem. During the past 20 ing infarcts, and methods of monitoring the pa years, hospitals have been developing coronary tient with myocardial ischemia. A major focus of care units as the specialized inhospital facilities for the text is on "coronary care." As indicated above, such patients. For the past 15 years, many com during the past 20 years five distinct phases of munities have employed paramedical personnel coronary care have evolved: (a) prehospital, (b) to extend the principles of "coronary care" to the postadmission, (c) coronary care unit, (d) predis site of the patient who develops the problem. charge, and (e) convalescent. Cardiac rehabilitation programs have also been The section on pathophysiology begins with a established to facilitate the return to function of chapter by Greenfield and Rembert discussing patients who have had acute coronary insuffi the factors that determine the transmural distri ciency. More recently, aggressive medical and bution of blood flow. Reimer then shows the surgical techniques have been developed to either relationship between coronary blood flow and prevent or limit the extent of myocardial necrosis both reversible and irreversible damage to the that develops due to acute coronary insufficiency. myocardium.

Evidence-Based Cardiology

Evidence-Based Cardiology PDF Author: Salim Yusuf
Publisher: John Wiley & Sons
ISBN: 0470986875
Category : Medical
Languages : en
Pages : 1024

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Book Description
This second editionis a ground-breaking clinical text with a strong emphasis on rigorous evidence. Leaders in the field discuss best practice in the light of systematic reviews and randomised control trials, and how best to treat where the information is less clear. Case histories provide intriguing discussions on how to apply the evidence in real life situations. Evidence-based Cardiology also includes free access to the latest evidence, which is automatically posted on a companion website.

Vascular Complications of Surgery and Intervention

Vascular Complications of Surgery and Intervention PDF Author: Ramyar Gilani
Publisher: Springer Nature
ISBN: 3030867137
Category : Medical
Languages : en
Pages : 284

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Book Description
The concept for this book evolved over many years of intense clinical practice during which a wide variety of vascular complications were encountered as a result of other surgical or interventional procedures. In this book, the authors describe cohesive efforts by experts in the field as they commit to advancing health care quality by all professionals. It should be noted at the outset that the book does not discuss various non-vascular or systemic complications of patients undergoing vascular interventions such as myocardial infarction, renal or respiratory failure. Instead, the content is divided into four separate sections. The material begins with an introduction to vascular anatomy and function. There follows a section addressing specific complications of the vascular system that can occur in any patient, sometimes even without intervention. The third section addresses complications specific to interventions and surgical procedures. The final section is dedicated to the delayed and long-term sequelae attributable to the most commonly encountered vascular complications. Vascular Complications of Surgery and Intervention: A Practical Guide is targeted towards dedicated health care professionals managing patients affected by inadvertent but potentially disastrous vascular complications and for those practitioners performing interventions either directly upon the vascular system or procedures that have potential for collateral impact.

Coronary Heart Disease

Coronary Heart Disease PDF Author: Zeev Vlodaver
Publisher: Springer Science & Business Media
ISBN: 146141475X
Category : Medical
Languages : en
Pages : 543

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Book Description
Coronary Heart Disease: Clinical, Pathological, Imaging, and Molecular Profiles presents a comprehensive picture of ischemic heart disease for practitioners, students, and investigators dealing with the varied facets of this complex subject. Individual chapters introduce the anatomy of the coronary blood vessels and cardiac development, while others consider current imaging modalities utilized for ischemic heart disease, including stress echo, nuclear diagnostic tests, non-invasive coronary artery imaging, and coronary angiography. Imaging chapters provide key clinical information on techniques and indications, and include examples of both normal and abnormal patterns. The principle thrust of the book concerns coronary atherosclerosis, the pathology of which is presented in conjunction with the results of anatomic, non-invasive imaging and angiographic studies. Related chapters cover atherogenesis, presenting new insights into the pathophysiology of the vulnerable plaque, the role of progenitor cells in vascular injury, inflammation and atherogenesis, and the genomics of vascular remodeling. Additional topics covered include angina pectoris, acute coronary syndromes, healed myocardial infarction and congestive heart failure, catheter-based and surgical revascularization, and surgical treatment of myocardial infarction and its sequelae. With contributions from a diverse group of internationally-known physicians with broad experience in the diagnosis and treatment of coronary heart disease, this book will be a valuable resource for practitioners in clinical cardiology, thoracic surgery, pathology, and cardiovascular molecular research, as well as for students in training.

Pharmacotherapeutic Management of Cardiovascular Disease Complications: A Textbook for Medical Students

Pharmacotherapeutic Management of Cardiovascular Disease Complications: A Textbook for Medical Students PDF Author: A. Bharath Kumar
Publisher: Bentham Science Publishers
ISBN: 9811468192
Category : Medical
Languages : en
Pages : 361

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Book Description
Pharmacotherapeutic Management of Cardiovascular Disease Complications is an essential textbook which comprehensively informs the reader about a broad variety of cardiovascular pathologies and their management through drug therapy. Key Features:- Features 22 chapters, with 17 chapters dedicated to the management of a wide range of cardiomyopathies and related complications- Introduces readers to heart anatomy and physiology, for both medical and pharmacology students- Covers information on cardiovascular disease biomarkers as well as current and new technologies for diagnostic procedures- Provides additional information on different aspects of cardiovascular disease treatment including etiological factors, prevalence, pathogenesis, clinical symptoms, diagnosis and prevention factors, risk screening and complications- Informs readers on the role of the clinical pharmacist in patient lifestyle modification for therapeutic plans, helping to reduce cardiovascular disease burden in clinical practice The broad coverage and easy-to-read organization of the topics covered on the subject make this textbook an ideal reference for medical students and health care professionals such as doctors, nurses, clinical pharmacists, community pharmacists and paramedics.

Coronary Pressure

Coronary Pressure PDF Author: N.H. Pijls
Publisher: Springer Science & Business Media
ISBN: 9401588341
Category : Medical
Languages : en
Pages : 348

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Book Description
Cardiologists must answer three important questions when evaluating and treating patients with a coronary artery stenosis. As a physiologist: "What is the effect of this stenosis on coronary blood flow and myocardial function?"; as a clinician: " Is this lesion responsible for the patient's symptoms?"; and finally as an interventionalist: "Will revascularization of this artery improve the patient?" Fundamentally, the answer to these questions can be given to a large extent by measuring coronary pressure. That is the rationale of writing this book. 1. 1 Historical overview. Andreas Gruentzig and most interventional cardiologists in the early days of PTCA, had the intuitive feeling that pressure measurements could help to establish the severity of a coronary stenosis and to monitor the progress and result of a coronary intervention. At that time, measuring coronary pressure by the balloon catheter was part of a standard procedure. A residual transstenotic gradient of less than 15 mmHg was generally considered as a good result. Later, however, it turned out that measuring these (resting) gradients with balloon catheters was inaccurate an only had a limited prognostic value. Moreover, because there was no consistent theory to correlate pressure measurements to blood flow, the interest in measuring coronary pressures faded and disappeared almost completely with the introduction of new balloon catheters not intended for pressure measurement.

Biomarkers in Cardiovascular Disease

Biomarkers in Cardiovascular Disease PDF Author: Vijay Nambi
Publisher: Elsevier Health Sciences
ISBN: 0323548369
Category : Medical
Languages : en
Pages : 199

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Book Description
Get a quick, expert overview of the ways in which biomarkers can be used to assess and guide the management of cardiovascular disease in the clinical setting. This concise, clinically-focused resource by Dr. Vijay Nambi consolidates today's available information on this rapidly changing topic into one convenient resource, making it an ideal, easy-to-digest reference for cardiology practitioners, fellows, and residents. - Covers lab standards and statistical interpretation of biomarkers with a clinical focus. - Discusses relevant conditions such as hypertension and diabetes as key markers of injury and prognosis. - Includes current information on biomarkers to assess and guide the management of heart failure, acute coronary syndrome, chest pain, shortness of breath, and more. - Concludes the book with a timely chapter on how biomarkers may guide cardiologists in the future.

The ESC Textbook of Intensive and Acute Cardiovascular Care

The ESC Textbook of Intensive and Acute Cardiovascular Care PDF Author: Marco Tubaro
Publisher: Oxford University Press
ISBN: 0192589199
Category : Medical
Languages : en
Pages : 2879

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Book Description
The ESC Textbook of Intensive and Acute Cardiovascular Care is the official textbook of the Acute Cardiovascular Care Association (ACVC) of the ESC. Cardiovascular diseases (CVDs) are a major cause of premature death worldwide and a cause of loss of disability-adjusted life years. For most types of CVD early diagnosis and intervention are independent drivers of patient outcome. Clinicians must be properly trained and centres appropriately equipped in order to deal with these critically ill cardiac patients. This new updated edition of the textbook continues to comprehensively approach all the different issues relating to intensive and acute cardiovascular care and addresses all those involved in intensive and acute cardiac care, not only cardiologists but also critical care specialists, emergency physicians and healthcare professionals. The chapters cover the various acute cardiovascular diseases that need high quality intensive treatment as well as organisational issues, cooperation among professionals, and interaction with other specialities in medicine. SECTION 1 focusses on the definition, structure, organisation and function of ICCU's, ethical issues and quality of care. SECTION 2 addresses the pre-hospital and immediate in-hospital (ED) emergency cardiac care. SECTIONS 3-5 discuss patient monitoring, diagnosis and specific procedures. Acute coronary syndromes (ACS), acute decompensated heart failure (ADHF), and serious arrhythmias form SECTIONS 6-8. The main other cardiovascular acute conditions are grouped in SECTION 9. Finally SECTION 10 is dedicated to the many concomitant acute non-cardiovascular conditions that contribute to the patients' case mix in ICCU. This edition includes new chapters such as low cardiac output states and cardiogenic shock, and pacemaker and ICDs: troubleshooting and chapters have been extensively revised. Purchasers of the print edition will also receive an access code to access the online version of the textbook which includes additional figures, tables, and videos to better to better illustrate diagnostic and therapeutic techniques and procedures in IACC. The third edition of the ESC Textbook of Intensive and Acute Cardiovascular Care will establish a common basis of knowledge and a uniform and improved quality of care across the field.