Compartmental Analysis in Biology and Medicine PDF Download
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Author: John Alfred Jacquez
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 586
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Book Description
Deals with basic linear and nonlinear systems and graph theory, distribution of tracer-labeled materials, connectivity, and identifiability
Author: John Alfred Jacquez
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 586
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Book Description
Deals with basic linear and nonlinear systems and graph theory, distribution of tracer-labeled materials, connectivity, and identifiability
Author: John Alfred Jacquez
Publisher:
ISBN:
Category : Compartmental analysis (Biology)
Languages : en
Pages : 536
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Book Description
Author: Vincenzo Capasso
Publisher: Springer Science & Business Media
ISBN: 3642932878
Category : Mathematics
Languages : en
Pages : 543
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Book Description
Author: Reginald Frederick Brown
Publisher: CRC Press
ISBN: 9780856264337
Category : Computers
Languages : en
Pages : 698
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Book Description
Author: Claudio Cobelli
Publisher: Elsevier
ISBN: 0080559980
Category : Technology & Engineering
Languages : en
Pages : 337
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Book Description
This unified modeling textbook for students of biomedical engineering provides a complete course text on the foundations, theory and practice of modeling and simulation in physiology and medicine. It is dedicated to the needs of biomedical engineering and clinical students, supported by applied BME applications and examples. Developed for biomedical engineering and related courses: speaks to BME students at a level and in a language appropriate to their needs, with an interdisciplinary clinical/engineering approach, quantitative basis, and many applied examples to enhance learning Delivers a quantitative approach to modeling and also covers simulation: the perfect foundation text for studies across BME and medicine Extensive case studies and engineering applications from BME, plus end-of-chapter exercises
Author: Karl-ernst Erich Biebler
Publisher: World Scientific
ISBN: 9814522244
Category : Mathematics
Languages : en
Pages : 349
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Book Description
This book presents methods of mathematical modeling from two points of view. Splines provide a general approach while compartment models serve as examples for context related to modeling. The preconditions and characteristics of the developed mathematical models as well as the conditions surrounding data collection and model fit are taken into account. The substantial statements of this book are mathematically proven. The results are ready for application with examples and related program codes given.In this book, splines are algebraically developed such that the reader or user can easily understand and vary the numerical construction of the different kinds of spline functions. The classical compartment models of the pharmacokinetics are systematically analyzed and connected with lifetime distributions. As such, parameter estimation and model fit can be treated statistically with a varied minimum chi-square method. This method is applicable for single kinetics and also allows the calculation of average kinetics.
Author: John H. Lawrence
Publisher: Academic Press
ISBN: 1483215016
Category : Science
Languages : en
Pages : 486
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Book Description
Advances in Biological and Medical Physics, Volume 17 covers articles on the advances in biological and medical physics. The book presents articles on energy transfer dynamics; the molecular mechanism of DNA repair after ionizing radiation; and mechanisms of prereplication repair of DNA breaks in gamma-irradiated E. coli cells. The text then describes articles about damages to DNA that result in neoplastic transformation; the nature of radiation and chemically-induced lesions and the role of cellular mechanisms in cell survival and mutagenesis; as well as the nature of the target in the biological action of ionizing radiation. The gated detection and analysis of nanosecond pulse excitation and the time-profile multicomponent analysis using nonintrusive mass spectrometry are also considered. The book further tackles the technique of acoustic microscopy in biophysics and the use of electron spin echo spectroscopy in the study of biological structure and function. The text also describes radiation as an oncogen and as a cocarcinogen at the cellular level and speculates on some possible molecular and cellular mechanisms of radiocarcinogenesis. Biological and medical physicists, biologists, and chemists will find the book invaluable.
Author: Isabelle Queinnec
Publisher: Springer
ISBN: 3540719881
Category : Technology & Engineering
Languages : en
Pages : 342
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Book Description
Creating some links between control feedback and biology modeling communities based on similarities in modeling, observing and perceiving alive structures, and analyzing interconnections between biological structures and subsystems was the main objective of this volume. In this context, biology systems need appropriate analysis tools due to their structure and hierarchy, complexity and environment interference, and we believe that these aspects may generate interesting research topics in control area. Indeed, several works, raising the potential impact of control developments to bring some beginning of answers in the context of biological systems, have been published in the recent years. The idea of this book was conceived in the context mentioned above with the objective to help in claiming many of the problems for control researchers, starting discussions and opening interactive debates between the control and biology communities, and, finally, to alert graduate students to the many interesting ideas at the frontier between control feedback theory and biology.
Author: Joseph DiStefano III
Publisher: Academic Press
ISBN: 0124104932
Category : Science
Languages : en
Pages : 886
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Book Description
Dynamic Systems Biology Modeling and Simuation consolidates and unifies classical and contemporary multiscale methodologies for mathematical modeling and computer simulation of dynamic biological systems – from molecular/cellular, organ-system, on up to population levels. The book pedagogy is developed as a well-annotated, systematic tutorial – with clearly spelled-out and unified nomenclature – derived from the author's own modeling efforts, publications and teaching over half a century. Ambiguities in some concepts and tools are clarified and others are rendered more accessible and practical. The latter include novel qualitative theory and methodologies for recognizing dynamical signatures in data using structural (multicompartmental and network) models and graph theory; and analyzing structural and measurement (data) models for quantification feasibility. The level is basic-to-intermediate, with much emphasis on biomodeling from real biodata, for use in real applications. - Introductory coverage of core mathematical concepts such as linear and nonlinear differential and difference equations, Laplace transforms, linear algebra, probability, statistics and stochastics topics - The pertinent biology, biochemistry, biophysics or pharmacology for modeling are provided, to support understanding the amalgam of "math modeling with life sciences - Strong emphasis on quantifying as well as building and analyzing biomodels: includes methodology and computational tools for parameter identifiability and sensitivity analysis; parameter estimation from real data; model distinguishability and simplification; and practical bioexperiment design and optimization - Companion website provides solutions and program code for examples and exercises using Matlab, Simulink, VisSim, SimBiology, SAAMII, AMIGO, Copasi and SBML-coded models - A full set of PowerPoint slides are available from the author for teaching from his textbook. He uses them to teach a 10 week quarter upper division course at UCLA, which meets twice a week, so there are 20 lectures. They can easily be augmented or stretched for a 15 week semester course - Importantly, the slides are editable, so they can be readily adapted to a lecturer's personal style and course content needs. The lectures are based on excerpts from 12 of the first 13 chapters of DSBMS. They are designed to highlight the key course material, as a study guide and structure for students following the full text content - The complete PowerPoint slide package (~25 MB) can be obtained by instructors (or prospective instructors) by emailing the author directly, at:
[email protected]
Author: Shein-Chung Chow
Publisher: CRC Press
ISBN: 1420011677
Category : Mathematics
Languages : en
Pages : 758
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Book Description
Preeminent Experts Update a Well-Respected BookTaking into account the regulatory and scientific developments that have occurred since the second edition, Design and Analysis of Bioavailability and Bioequivalence Studies, Third Edition provides a complete presentation of the latest progress of activities and results in bioavailability and bioequiva
