Collaborative Genomics Projects: A Comprehensive Guide

Collaborative Genomics Projects: A Comprehensive Guide PDF Author: Margi Sheth
Publisher: Academic Press
ISBN: 0128023686
Category : Science
Languages : en
Pages : 146

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Book Description
Collaborative Genomics Projects: A Comprehensive Guide contains operational procedures, policy considerations, and the many lessons learned by The Cancer Genome Atlas Project. This book guides the reader through methods in patient sample acquisition, the establishment of data generation and analysis pipelines, data storage and dissemination, quality control, auditing, and reporting. This book is essential for those looking to set up or collaborate within a large-scale genomics research project. All authors are contributors to The Cancer Genome Atlas (TCGA) Program, a NIH- funded effort to generate a comprehensive catalog of genomic alterations in more than 35 cancer types. As the cost of genomic sequencing is decreasing, more and more researchers are leveraging genomic data to inform the biology of disease. The amount of genomic data generated is growing exponentially, and protocols need to be established for the long-term storage, dissemination, and regulation of this data for research. The book's authors create a complete handbook on the management of research projects involving genomic data as learned through the evolution of the TCGA program, a project that was primarily carried out in the US, but whose impact and lessons learned can be applied to international audiences. - Establishes a framework for managing large-scale genomic research projects involving multiple collaborators - Describes lessons learned through TCGA to prepare for potential roadblocks - Evaluates policy considerations that are needed to avoid pitfalls - Recommends strategies to make project management more efficient

Collaborative Genomics Projects: A Comprehensive Guide

Collaborative Genomics Projects: A Comprehensive Guide PDF Author: Margi Sheth
Publisher: Academic Press
ISBN: 0128023686
Category : Science
Languages : en
Pages : 146

Get Book Here

Book Description
Collaborative Genomics Projects: A Comprehensive Guide contains operational procedures, policy considerations, and the many lessons learned by The Cancer Genome Atlas Project. This book guides the reader through methods in patient sample acquisition, the establishment of data generation and analysis pipelines, data storage and dissemination, quality control, auditing, and reporting. This book is essential for those looking to set up or collaborate within a large-scale genomics research project. All authors are contributors to The Cancer Genome Atlas (TCGA) Program, a NIH- funded effort to generate a comprehensive catalog of genomic alterations in more than 35 cancer types. As the cost of genomic sequencing is decreasing, more and more researchers are leveraging genomic data to inform the biology of disease. The amount of genomic data generated is growing exponentially, and protocols need to be established for the long-term storage, dissemination, and regulation of this data for research. The book's authors create a complete handbook on the management of research projects involving genomic data as learned through the evolution of the TCGA program, a project that was primarily carried out in the US, but whose impact and lessons learned can be applied to international audiences. - Establishes a framework for managing large-scale genomic research projects involving multiple collaborators - Describes lessons learned through TCGA to prepare for potential roadblocks - Evaluates policy considerations that are needed to avoid pitfalls - Recommends strategies to make project management more efficient

Mapping and Sequencing the Human Genome

Mapping and Sequencing the Human Genome PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309038405
Category : Science
Languages : en
Pages : 128

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Book Description
There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.

Thymic Tumors Unveiled: A Comprehensive Guide to Diagnosis, Treatment, and Hope

Thymic Tumors Unveiled: A Comprehensive Guide to Diagnosis, Treatment, and Hope PDF Author: Dr. Spineanu Eugenia
Publisher: Dr. Spineanu Eugenia
ISBN:
Category : Medical
Languages : en
Pages : 362

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Book Description
Are you or a loved one facing the challenges of thymic tumors? Discover hope, empowerment, and expert guidance in "Thymic Tumors Unveiled: A Comprehensive Guide to Diagnosis, Treatment, and Hope." This comprehensive treatise offers a lifeline to those navigating the rare and complex world of thymic tumors. From understanding the disease's origins, anatomy, and genetic factors to exploring cutting-edge treatments and the latest in precision medicine, this book covers it all. Inside, you'll find: In-Depth Knowledge: Dive into the intricacies of thymic tumors, from their historical perspective to the latest research breakthroughs. Understand the anatomy of the thymus gland, the role of genetics, and the influence of environmental factors. Cutting-Edge Therapies: Explore the future of thymic tumor treatment with precision medicine, immunotherapies, and targeted therapies. Learn how advancements in molecular diagnostics are reshaping the landscape of care. Patient-Centered Care: Discover how patient advocacy groups and support networks offer invaluable resources, emotional support, and insights to navigate the thymic tumor journey. Global Access to Care: Learn about the vision for equitable access to thymic tumor care, breaking down geographical barriers and promoting international collaboration. Data-Driven Insights: Explore the role of data-driven decision-making, predictive analytics, and real-world evidence in shaping the future of thymic tumor management. "Thymic Tumors Unveiled" is more than a book; it's a beacon of hope for patients and their families. With clear and accessible language, this treatise empowers you to become an informed advocate for your health, guiding you towards better outcomes and improved quality of life. Join the global movement towards a brighter future for thymic tumor patients. Whether you're a healthcare professional, a patient, or a caregiver, this treatise offers essential knowledge, inspiration, and a vision for a world where thymic tumors are better understood, treated, and ultimately conquered.

Biology Essentials: A Study Guide

Biology Essentials: A Study Guide PDF Author: Cybellium
Publisher: Cybellium
ISBN: 1836794991
Category : Science
Languages : en
Pages : 226

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Book Description
Welcome to the forefront of knowledge with Cybellium, your trusted partner in mastering the cutting-edge fields of IT, Artificial Intelligence, Cyber Security, Business, Economics and Science. Designed for professionals, students, and enthusiasts alike, our comprehensive books empower you to stay ahead in a rapidly evolving digital world. * Expert Insights: Our books provide deep, actionable insights that bridge the gap between theory and practical application. * Up-to-Date Content: Stay current with the latest advancements, trends, and best practices in IT, Al, Cybersecurity, Business, Economics and Science. Each guide is regularly updated to reflect the newest developments and challenges. * Comprehensive Coverage: Whether you're a beginner or an advanced learner, Cybellium books cover a wide range of topics, from foundational principles to specialized knowledge, tailored to your level of expertise. Become part of a global network of learners and professionals who trust Cybellium to guide their educational journey. www.cybellium.com

Study Guide to Zoology

Study Guide to Zoology PDF Author: Cybellium
Publisher: Cybellium
ISBN: 1836795416
Category : Science
Languages : en
Pages : 233

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Book Description
Welcome to the forefront of knowledge with Cybellium, your trusted partner in mastering the cutting-edge fields of IT, Artificial Intelligence, Cyber Security, Business, Economics and Science. Designed for professionals, students, and enthusiasts alike, our comprehensive books empower you to stay ahead in a rapidly evolving digital world. * Expert Insights: Our books provide deep, actionable insights that bridge the gap between theory and practical application. * Up-to-Date Content: Stay current with the latest advancements, trends, and best practices in IT, Al, Cybersecurity, Business, Economics and Science. Each guide is regularly updated to reflect the newest developments and challenges. * Comprehensive Coverage: Whether you're a beginner or an advanced learner, Cybellium books cover a wide range of topics, from foundational principles to specialized knowledge, tailored to your level of expertise. Become part of a global network of learners and professionals who trust Cybellium to guide their educational journey. www.cybellium.com

Exploring Biomedical Engineering

Exploring Biomedical Engineering PDF Author: Cybellium
Publisher: Cybellium
ISBN: 1836791194
Category : Technology & Engineering
Languages : en
Pages : 226

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Book Description
Welcome to the forefront of knowledge with Cybellium, your trusted partner in mastering the cutting-edge fields of IT, Artificial Intelligence, Cyber Security, Business, Economics and Science. Designed for professionals, students, and enthusiasts alike, our comprehensive books empower you to stay ahead in a rapidly evolving digital world. * Expert Insights: Our books provide deep, actionable insights that bridge the gap between theory and practical application. * Up-to-Date Content: Stay current with the latest advancements, trends, and best practices in IT, Al, Cybersecurity, Business, Economics and Science. Each guide is regularly updated to reflect the newest developments and challenges. * Comprehensive Coverage: Whether you're a beginner or an advanced learner, Cybellium books cover a wide range of topics, from foundational principles to specialized knowledge, tailored to your level of expertise. Become part of a global network of learners and professionals who trust Cybellium to guide their educational journey. www.cybellium.com

A Guide to the Human Genome Project

A Guide to the Human Genome Project PDF Author: Susan L. Speaker
Publisher: Chemical Heritage Foundation
ISBN: 9780941901109
Category : Science
Languages : en
Pages : 44

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Book Description
This simple, concise introduction to the HGP for the general reader explores the origins of the genome project and reactions in the scientific community; important technologies and techniques; institutions connected with the HGP, including designated genome centers, important suppliers of resources, and corporations; systems of communication; and ethical, legal, and social issues. A publication of the Biomolecular Sciences Initiative of CHF's Beckman Center for the History of Chemistry.

ICRF Handbook of Genome Analysis

ICRF Handbook of Genome Analysis PDF Author: N. S. Spurr
Publisher: John Wiley & Sons
ISBN: 1444313479
Category : Science
Languages : en
Pages : 1038

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Book Description
The combined power of genetic analysis and recombinant DNA technology to analyse entire genomes has moved biomedical research into a new and revolutionary phase. The complete sequencing and mapping of the human genome, as well as the genomes of other model organisms, will be the basis for our future understanding of human disease, and will allow us to answer fundamental questions about development and evolution. T The new ICRF Handbook of Genome Analysis is the essential guide to the enormous range of techniques available to the researcher for both the genetic and physical mapping of the genome, as well as the sequencing and analysis of DNA. It is both a protocol manual and a comprehensive information resource. Written by international experts, each chapter presents a state-of-the-art review of a methodology. Methods are fully described and evaluated; their advantages and disadvantages discussed; and their suitability for different investigations considered. Step-by-step protocols, including computer analyses, are given for 123 essential experimental procedures. 'Troubleshooting' sections discuss possible reasons for failure and offer remedies. The primary focus is on human genetics and the benefits of an understanding of the genome for the diagnosis and treatment of human disease. The book also considers the current state of progress in the analysis of genomes of many model organisms, including plants. A major part of the work provides detail on Internet resources as well as basic data on human and other genomes, including mapped disease genes and mouse knockouts. Covers not only the human genome in relation to cancers and other human diseases, but also the genomes of all important model organisms Contains 123 easy-to-follow protocols for essential experimental procedures Reviews a vast range of other information resources, including journals and the Internet * provides an invaluable listing of suppliers of laboratory materials Has been written by international experts from their own practical experience Is mandated by the Imperial Cancer Research Fund - a leader in research in this field Has a sturdy spiral binding within a hardback case for ease of use in the lab

Introduction to Particle Physics

Introduction to Particle Physics PDF Author:
Publisher: Cybellium
ISBN: 1836790619
Category :
Languages : en
Pages : 263

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Book Description
Welcome to the forefront of knowledge with Cybellium, your trusted partner in mastering the cutting-edge fields of IT, Artificial Intelligence, Cyber Security, Business, Economics and Science. Designed for professionals, students, and enthusiasts alike, our comprehensive books empower you to stay ahead in a rapidly evolving digital world. * Expert Insights: Our books provide deep, actionable insights that bridge the gap between theory and practical application. * Up-to-Date Content: Stay current with the latest advancements, trends, and best practices in IT, Al, Cybersecurity, Business, Economics and Science. Each guide is regularly updated to reflect the newest developments and challenges. * Comprehensive Coverage: Whether you're a beginner or an advanced learner, Cybellium books cover a wide range of topics, from foundational principles to specialized knowledge, tailored to your level of expertise. Become part of a global network of learners and professionals who trust Cybellium to guide their educational journey. www.cybellium.com

The Postgenomic Condition

The Postgenomic Condition PDF Author: Jenny Reardon
Publisher: University of Chicago Press
ISBN: 022651045X
Category : Medical
Languages : en
Pages : 320

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Book Description
The postgenomic condition: an introduction -- The information of life or the life of information? -- Inclusion: can genomics be antiracist? -- Who represents the human genome? What is the human genome? -- Genomics for the people or the rise of the machines? -- Genomics for the 98 percent? -- The genomic open 2.0: the public v. the public -- Life on Third: knowledge and justice after the genome -- Epilogue