Planning Clinical Research

Planning Clinical Research PDF Author: Robert A. Parker
Publisher: Cambridge University Press
ISBN: 0521840635
Category : Mathematics
Languages : en
Pages : 445

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Book Description
Planning clinical research requires many decisions. The authors of this book explain key decisions with examples showing what works and what does not.

Planning Clinical Research

Planning Clinical Research PDF Author: Robert A. Parker
Publisher: Cambridge University Press
ISBN: 0521840635
Category : Mathematics
Languages : en
Pages : 445

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Book Description
Planning clinical research requires many decisions. The authors of this book explain key decisions with examples showing what works and what does not.

Cohort Studies in Health Sciences

Cohort Studies in Health Sciences PDF Author: R. Mauricio Barría
Publisher: Intechopen
ISBN: 1789236940
Category : Medical
Languages : en
Pages : 73

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Book Description
Introductory Chapter: The Contribution of Cohort Studies to Health Sciences.

Practical Psychiatric Epidemiology

Practical Psychiatric Epidemiology PDF Author: Jayati Das-Munshi
Publisher: Oxford University Press
ISBN: 0191054461
Category : Medical
Languages : en
Pages : 465

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Book Description
Epidemiology has been defined as the study of the distribution and determinants of health states or events in defined populations and its application to the control of health problems. Psychiatric epidemiology has continued to develop and apply these core principles in relation to mental health and mental disorders. This long-awaited second edition of Practical Psychiatric Epidemiology covers all of the considerable new developments in psychiatric epidemiology that have occurred since the first edition was published. It includes new content on key topics such as life course epidemiology, gene/environment interactions, bioethics, patient and public involvement in research, mixed methods research, new statistical methods, case registers, policy, and implementation. Looking to the future of this rapidly evolving scientific discipline and how it will to respond to the emerging opportunities and challenges posed by 'big data', new technologies, open science and globalisation, this new edition will continue to serve as an invaluable reference for clinicians in practice and in training. It will also be of interest to researchers in mental health and people studying or teaching psychiatric epidemiology at undergraduate or postgraduate level.

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide

Developing a Protocol for Observational Comparative Effectiveness Research: A User's Guide PDF Author: Agency for Health Care Research and Quality (U.S.)
Publisher: Government Printing Office
ISBN: 1587634236
Category : Medical
Languages : en
Pages : 236

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Book Description
This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)

A Unified Model of Cohort Mortality for Economic Analysis

A Unified Model of Cohort Mortality for Economic Analysis PDF Author: Adriana Lleras-Muney
Publisher: International Monetary Fund
ISBN: 151356949X
Category : Social Science
Languages : en
Pages : 67

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Book Description
We propose a dynamic production function of population health and mortality from birth onwards. Our parsimonious model provides an excellent fit for the mortality and survival curves for both primate and human populations since 1816. The model sheds light on the dynamics behind many phenomena documented in the literature, including (i) the existence and evolution of mortality gradients across socio-economic statuses, (ii) non-monotonic dynamic effects of in-utero shocks, (iii) persistent or “scarring” effects of wars and (iv) mortality displacement after large temporary shocks such as extreme weather.

Age-Period-Cohort Analysis

Age-Period-Cohort Analysis PDF Author: Yang Yang
Publisher: CRC Press
ISBN: 1466507535
Category : Mathematics
Languages : en
Pages : 352

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Book Description
This book explores the ways in which statistical models, methods, and research designs can be used to open new possibilities for APC analysis. Within a single, consistent HAPC-GLMM statistical modeling framework, the authors synthesize APC models and methods for three research designs: age-by-time period tables of population rates or proportions, repeated cross-section sample surveys, and accelerated longitudinal panel studies. They show how the empirical application of the models to various problems leads to many fascinating findings on how outcome variables develop along the age, period, and cohort dimensions.

Cohort Analysis in Social Research

Cohort Analysis in Social Research PDF Author: W.M. Mason
Publisher: Springer Science & Business Media
ISBN: 1461385369
Category : Business & Economics
Languages : en
Pages : 402

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Book Description
The existence of the present volume can be traced to methodological concerns about cohort analysis, all of which were evident throughout most of the social sciences by the late 1970s. For some social scientists, they became part of a broader discussion concerning the need for new analytical techniques for research based on longitudinal data. In 1976, the Social Science Research Council (SSRC), with funds from the National Institute of Education, established a Committee on the Methodology of Longitudinal Research. (The scholars who comprised this committee are listed at the front of this volume. ) As part of the efforts of this Committee, an interdisciplinary conference on cohort analysis was held in the summer of 1979, in Snowmass, Colorado. Much of the work presented here stems from that conference, the purpose of which was to promote the development of general methodological tools for the study of social change. The conference included five major presentations by (1) William Mason and Herbert Smith, (2) Karl J6reskog and Dag S6rbom, (3) Gregory Markus, (4) John Hobcraft, Jane Menken and Samuel Preston, and (5) Stephen Fienberg and William Mason. The formal presentations were each followed by extensive discussion, which involved as participants: Paul Baltes, William Butz, Philip Converse, Otis Dudley Duncan, David Freedman, William Meredith, John Nesselroade, Daniel Price, Thomas Pullum, Peter Read, Matilda White Riley, Norman Ryder, Warren Sanderson, Warner Schaie, Burton Singer, Nancy Tuma, Harrison White, and Halliman Winsborough.

Assessment of Cancer Screening

Assessment of Cancer Screening PDF Author: Pamela M. Marcus
Publisher: Springer Nature
ISBN: 3030945774
Category : Biology-Research
Languages : en
Pages : 138

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Book Description
Cancer screening is a prominent strategy in cancer control in the United States, yet the ability to correctly interpret cancer screening data eludes many researchers, clinicians, and policy makers. This open access primer rectifies that situation by teaching readers, in simple language and with straightforward examples, why and how the population-level cancer burden changes when screening is implemented, and how we assess whether that change is of benefit. This book provides an in-depth look at the many aspects of cancer screening and its assessment, including screening phenomena, performance measures, population-level outcomes, research designs, and other important and timely topics. Concise, accessible, and focused, Assessment of Cancer Screening: A Primer is best suited to those with education or experience in clinical research or public health in the United States - no previous knowledge of cancer screening assessment is necessary. This is the first text dedicated to cancer screening theory and methodology to be published in 20 years.

Drug Epidemiology and Post-Marketing Surveillance

Drug Epidemiology and Post-Marketing Surveillance PDF Author: Brian L. Strom
Publisher: Springer Science & Business Media
ISBN: 1489925872
Category : Medical
Languages : en
Pages : 171

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Book Description
This volume is a summary of material presented in the course given in the International School of Phannacology on "Drug Epidemiology and Post-Marketing Surveillance" between September 27 and October 8, 1990, at the "Ettore Majorana Center for Scientific Culture" in Erice, Sicily. The course, which was a NATO Advanced Study Institute, included lectures and workshops presented by experts in the new field of phannacoepidemiology. The material covered includes various approaches to spontaneous reporting of adverse drug reactions, including aggregate approaches, such as those used in France, and detailed analyses of individual reports, such as that done in The Netherlands and in Sweden. Also, included are studies using traditional epidemiology methods. In addition, modern pharmacoepidemiology makes considerable use of automated databases. As such, information is presented on their use as well. Phannacoepidemiology started in hospitals and some of the newest work in the field is returning to the hospital as a site for studies. Material on these topics was presented as well. Finally, selected new methodologic developments were outlined in specific examples presented that were of regulatory and commercial importance. This new field of phannacoepidemiology is exploding in interest internationally. Evidence of this is the increasing development of pharmacoepidemiology programs in industry, medical schools, pharmacy schools, and schools of public health. Also, there is a new International Society ofPhannacoepidemiology. Practitioners in this field tend to specialize in either analyses of spontaneous reporting or the use of formal epidemiologic techniques.

Cohort Analysis

Cohort Analysis PDF Author: Norval D. Glenn
Publisher: SAGE
ISBN: 9780761922155
Category : Mathematics
Languages : en
Pages : 76

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Book Description
A method for studying changes in group patterns -- particularly groups based on age -- cohort analysis seeks to isolate changes attributable to alterations in behaviour or attitudes within an age group; as an example of behaviour change, the pattern of consumption of alcohol within a cohort is analyzed.