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Author: Ruediger Mueller
Publisher: Springer
ISBN: 9781849963855
Category :
Languages : en
Pages : 772
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Book Description
Author: Ruediger Mueller
Publisher: Springer Science & Business Media
ISBN: 1447128702
Category : Medical
Languages : en
Pages : 1239
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Book Description
A huge number of therapeutic studies has been published in rheumatology and clinical immunology. This number grows substantially by the year. As such, it becomes increasingly difficult to keep track of this multitude of studies and the ensuing therapeutic trends. Further to this, a particular study can be referred to in a variety of ways, either as a shortened version of the title or an acronym, adding to the confusion. The book Clinical Trials in Rheumatology, Second Edition, provides an updated summary of the important studies in the field for easy reference. Every study is shown with name, acronym (if in existence), authors, complete citation, study design, and a short overview of the trial's data and main conclusions. An acronym finder is supplied at the beginning of the book. This book is a valuable reference tool for rheumatologists and other clinical specialties, as well as for research scientists interested in immunomodulatory and selected other drug therapies in rheumatologic diseases.
Author: Ruediger Mueller
Publisher: Springer
ISBN: 9781849963855
Category :
Languages : en
Pages : 772
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Book Description
Author: David M. Reid
Publisher: Springer Verlag
ISBN: 9781852338749
Category : Medical
Languages : en
Pages : 325
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Book Description
Designed to be a practical handbook on clinical trial management in these key therapeutic areas, 'Clinical Trials in Rheumatoid Arthritis and Osteoarthritis' is aimed at principal investigators pharmaceutical physicians and other pharmaceutical staff involved in the design, conduct and monitoring of these increasingly complex diseases. In the last several years a new classes of biologic agents have emerged and changed the treatment paradigm for patients, not only with classically defined rheumatoid arthritis, but also with other related diseases such as ankylosing spondylitis and psoriatic arthritis. Furthermore, osteoarthritis is a major disease state that is often treated by the rheumatologist, but is one where patient management programs are currently limited with a need for new therapeutic approaches. In both inflammatory and non-inflammatory arthritic conditions, clinical trials have become both large and complex due to the nature of the diseases, with ever-challenging new surrogate end-points being employed. Topics covered in this title will therefore include study design, clinical endpoints, technical issues, data collection, use of centralized medical image reading facilities and biochemical marker laboratories, as well as data analysis and future therapies. This book takes the user through the process step-by-step from start to finish, also providing a background on the regulatory guidelines, ethical implications, endpoints, and current therapies.
Author: Hasan Yazici
Publisher: Springer
ISBN: 3319083740
Category : Medical
Languages : en
Pages : 285
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Book Description
It is imperative that health professionals caring for patients with rheumatic diseases understand how to correctly interpret evidence in their field, taking into account the merits and shortcomings of available data. Understanding Evidence-Based Rheumatology offers a practical assessment of criteria, drugs, trials, and registries and provides useful tools for successfully interpreting this data. The book introduces readers to basic analysis of trial design, statistics and application of data through no-nonsense, easy-to-follow insights. Using numerous examples, chapters outline the difficulties physicians encounter when measuring disease activity in rheumatology and offer strategies for systematically approaching these situations. Ethical issues in study design and reporting are examined and the book closes with a summary of future directions for scientific and clinical studies in rheumatology. Understanding Evidence-Based Rheumatology is an invaluable resource for trainees, clinicians and scientists, preparing them with the necessary tools to correctly gather evidence and shed light on the difficult practice of rheumatology.
Author: Daniel J. Wallace
Publisher: Elsevier Health Sciences
ISBN: 0323655416
Category : Medical
Languages : en
Pages :
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Book Description
Guest edited by Drs. Daniel J. Wallace and R. Swamy Venuturupalli, this issue of Rheumatic Disease Clinics will cover several key areas of interest related to Best Practices and Challenges to the Practice of Rheumatology. This issue is one of four selected each year by our series Consulting Editor, Dr. Michael Weisman of Cedars-Sinai. Articles in this issue include, but are not limited to: The Economics of Rheumatology Practice in the United States, Manpower trends in rheumatology, Challenges to practicing rheumatology in an academic center, Challenges in practicing rheumatology in a government setting, Challenges to practicing rheumatology in a small private practice setting, Challenges to working in a large multispecialty organization, Challenges to practicing pediatric rheumatology, Clinical trials in rheumatology, Challenges in having an infusion center, Implementing treatment to target in the clinic, Future directions: implementing new technologies in clinical practice, Possible Challenges in Optimizing Medical Education for Rheumatologists, and the challenges of approaching and managing gout.
Author: George C. Tsokos
Publisher: Springer Science & Business Media
ISBN: 1592592392
Category : Medical
Languages : en
Pages : 648
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Book Description
Leading clinicians and clinical researchers discuss in practical detail the newest treatments used in rheumatic diseases, emphasizing-without neglecting current standard treatments-those experimental therapies now undergoing clinical trials and poised for early introduction into the rheumatology armamentarium. The diseases and therapeutic regimes examined here range from rheumatoid arthritis and its treatment by gene therapy, to osteoarthritis and systemic autoimune diseases. Each chapter is organized so that the busy clinician can quickly obtain all the information needed optimal patient treatment. This includes an analysis of the pathogenic mechanisms that explain the molecular basis of the newer therapeutics, reviews of animal data and the results of clinical trials, and recommendations concerning use, side effects, and precautions.
Author: David Rosenbloom
Publisher: Greenwood
ISBN:
Category : Medical
Languages : en
Pages : 408
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Book Description
Author: Richard A. Watts
Publisher: OUP Oxford
ISBN: 019151280X
Category : Medical
Languages : en
Pages : 456
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Book Description
Rheumatic disease is a major cause of morbidity and disability in the Western world. There have been major developments in our understanding of the causes of rheumatic disease and in their treatment during the last half-century, and there are relatively few papers which can be regarded as truly 'landmark' in their construction and subsequent findings. Part of the Landmark Papers in series, this book provides a detailed review of the seminal papers that have paved the way for breakthroughs in the clinical management of the entire spectrum of rheumatic diseases.
Author: Henry Scammell
Publisher: M Evans & Company
ISBN: 9780871316905
Category : Health & Fitness
Languages : en
Pages : 276
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Book Description
The most important news in half a century. DSThe Midwest Book Review
Author: Jack Cush
Publisher: Elsevier Health Sciences
ISBN: 145575059X
Category : Medical
Languages : en
Pages : 240
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Book Description
Edited by Drs. Jack Cush and Kathryn Dao, this issue of Rheumatic Disease Clinics of North America addresses one of the most significant issues facing the rheumatologist today––drug safety in a changing world where rheumatoid arthritis (RA) severity is less, patients are being identified and treated at a very early stage, and prevention is on the horizon. Topics covered include: communicating the risk of side effects, urate-lowering therapies, biphosphonates, biologics, malignancy risks, and administering therapies to patients with co-morbidities.