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Author: Cherie Winner
Publisher: Twenty-First Century Books
ISBN: 0822566060
Category : Juvenile Nonfiction
Languages : en
Pages : 114
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Book Description
A history of the art of transfusions and a scientific discourse on the chemistry of blood.
Author: Cherie Winner
Publisher: Twenty-First Century Books
ISBN: 0822566060
Category : Juvenile Nonfiction
Languages : en
Pages : 114
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Book Description
A history of the art of transfusions and a scientific discourse on the chemistry of blood.
Author: Mary C. Earle
Publisher: Church Publishing, Inc.
ISBN: 0819227625
Category : Religion
Languages : en
Pages : 113
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Book Description
Each chapter in Marvelously Made focuses on a vital part of the body (the heart, the lungs, the brain, the joints); relates an anecdote from the author’s experience; provides reader-friendly(i.e., not overly technical) information about the wonders of the organ or body part, and offers a prayer and a set of “gratitude practices”—physical and spiritual meditation exercises to deepen the reader’s appreciation of the body.
Author: Roland N. Pittman
Publisher: Biota Publishing
ISBN: 1615047212
Category : Medical
Languages : en
Pages : 117
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Book Description
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Author: W. Mark Saltzman
Publisher: Oxford University Press
ISBN: 019802469X
Category : Medical
Languages : en
Pages : 385
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Book Description
Synthetic materials are a tremendous potential resource for treating human disease. For the rational design of many of these biomaterials it is necessary to have an understanding of polymer chemistry and polymer physics. Equally important to those two fields is a quantitative understanding of the principles that govern rates of drug transport, reaction, and disappearance in physiological and pathological situations. This book is a synthesis of these principles, providing a working foundation for those in the field of drug delivery. It covers advanced drug delivery and contemporary biomaterials.
Author: Albert Edwin Keigwin
Publisher:
ISBN:
Category : Life
Languages : en
Pages : 272
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Book Description
Author: Harry Salem
Publisher: CRC Press
ISBN: 9781439805435
Category : Medical
Languages : en
Pages : 198
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Book Description
New Technologies and Concepts for Reducing Drug Toxicities provides a complete compendium of new information for improving the effectiveness and safety of therapeutic agents. The book offers insight into safe dosage forms of the future and the application of innovative technologies.
Author: Peter R. Kvietys
Publisher: Morgan & Claypool Publishers
ISBN: 1615041176
Category : Medical
Languages : en
Pages : 127
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Book Description
The microcirculation of the gastrointestinal tract is under the control of both myogenic and metabolic regulatory systems. The myogenic mechanism contributes to basal vascular tone and the regulation of transmural pressure, while the metabolic mechanism is responsible for maintaining an appropriate balance between O2 demand and O2 delivery. In the postprandial state, hydrolytic products of food digestion elicit a hyperemia, which serves to meet the increased O2 demand of nutrient assimilation. Metabolically linked factors (e.g., tissue pO2, adenosine) are primarily responsible for this functional hyperemia. The fenestrated capillaries of the gastrointestinal mucosa are relatively permeable to small hydrolytic products of food digestion (e.g., glucose), yet restrict the transcapillary movement of larger molecules (e.g., albumin). This allows for the absorption of hydrolytic products of food digestion without compromising the oncotic pressure gradient governing transcapillary fluid movement and edema formation. The gastrointestinal microcirculation is also an important component of the mucosal defense system whose function is to prevent (and rapidly repair) inadvertent epithelial injury by potentially noxious constituents of chyme. Two pathological conditions in which the gastrointestinal circulation plays an important role are ischemia/reperfusion and chronic portal hypertension. Ischemia/reperfusion results in mucosal edema and disruption of the epithelium due, in part, to an inflammatory response (e.g., increase in capillary permeability to macromolecules and neutrophil infiltration). Chronic portal hypertension results in an increase in gastrointestinal blood flow due to an imbalance in vasodilator and vasoconstrictor influences on the microcirculation. Table of Contents: Introduction / Anatomy / Regulation of Vascular Tone and Oxygenation / Extrinsic Vasoregulation: Neural and Humoral / Postprandial Hyperemia / Transcapillary Solute Exchange / Transcapillary Fluid Exchange / Interaction of Capillary and Interstitial Forces / Gastrointestinal Circulation and Mucosal Defense / Gastrointestinal Circulation and Mucosal Pathology I: Ischemia/Reperfusion / Gastrointestinal Circulation and Mucosal Pathology II: Chronic Portal Hypertension / Summary and Conclusions / References / Author Biography
Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 1252
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Book Description
Author:
Publisher:
ISBN:
Category : Music
Languages : en
Pages : 846
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Book Description
Author: Francesco M. Veronese
Publisher: Springer Science & Business Media
ISBN: 3764386797
Category : Medical
Languages : en
Pages : 289
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Book Description
PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development.
