Cholecystokinin Antagonists in Gastroenterology PDF Download
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Author: Guido Adler
Publisher: Springer Science & Business Media
ISBN: 3642763626
Category : Medical
Languages : en
Pages : 345
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Book Description
A new presentation of physiological regulatory mechanisms and therapeutic applications is given in this book. It represents a collection of the most up-to-date information in cholecystokinin (CCK) research, especially focusing on the development and characterization of CCK antagonists. The book contains chapters on the synthesis, biochemical and pharmacological characterization of potent and selective CCK antagonists as well as physiological applications of these compounds. The last section of the book is devoted to the involvement of CCK in pathological states and potential clinical applications of CCK antagonists.
Author: Guido Adler
Publisher: Springer Science & Business Media
ISBN: 3642763626
Category : Medical
Languages : en
Pages : 345
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Book Description
A new presentation of physiological regulatory mechanisms and therapeutic applications is given in this book. It represents a collection of the most up-to-date information in cholecystokinin (CCK) research, especially focusing on the development and characterization of CCK antagonists. The book contains chapters on the synthesis, biochemical and pharmacological characterization of potent and selective CCK antagonists as well as physiological applications of these compounds. The last section of the book is devoted to the involvement of CCK in pathological states and potential clinical applications of CCK antagonists.
Author: Gary McCleane
Publisher: CRC Press
ISBN: 9780789028938
Category : Health & Fitness
Languages : en
Pages : 162
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Book Description
Examine the strong evidence of this unrealized pain management tool Cholecystokinin (CCK), the regulatory peptide hormone found primarily in the gastrointestinal tract that works as a neurotransmitter throughout the nervous system, has been researched for years. CCK antagonists in conjunction with opioids are beginning to be seen as having possible major therapeutic benefits in pain management. Cholecystokinin and Its Antagonists in Pain Management is an extensive examination that gathers the mounting compelling evidence into one comprehensive source. Here researchers, neuroscientists, physicians, and pharmacy professionals are given the research and findings they need to explore the possible applications of CCK antagonists for a variety of illnesses. Cholecystokinin and Its Antagonists in Pain Management extensively describes opioids in pain management, CCK and the body’s uses for the chemical, CCK receptor antagonists, and the evidence that points to its being a possible breakthrough application in pain management. Various animal studies are offered that present a convincing view of what may be the future of chronic pain management, with less side effects and a reduction in analgesic tolerance than when opioids are used alone. Potential uses of CCK antagonists are clearly discussed. The book is comprehensively referenced and provides several tables and graphs to fully illustrate the research findings. Topics in Cholecystokinin and Its Antagonists in Pain Management include: in vivo localization of CCK CCK as a gut and nervous system peptide factors that increase CCK anti-opioid effects CCK receptor antagonists pro-analgesic effect of CCK antagonists CCK antagonists reducing analgesic tolerance to opioids safety of combining opioids and CCK antagonists human clinical application of CCK antagonists Cholecystokinin and Its Antagonists in Pain Management is a crucial source of the latest information and research results on CCK that is certain to be important for neuroscientists, clinicians, and pharmaceutical industry professionals.
Author: Rex Y. Wang
Publisher: Alan R. Liss
ISBN:
Category : Medical
Languages : en
Pages : 384
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Book Description
Author: Guido Adler
Publisher: Springer
ISBN: 9783540535829
Category : Medical
Languages : en
Pages : 233
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Book Description
A new presentation of physiological regulatory mechanisms and therapeutic applications is given in this book. It represents a collection of the most up-to-date information in cholecystokinin (CCK) research, especially focusing on the development and characterization of CCK antagonists. The book contains chapters on the synthesis, biochemical and pharmacological characterization of potent and selective CCK antagonists as well as physiological applications of these compounds. The last section of the book is devoted to the involvement of CCK in pathological states and potential clinical applications of CCK antagonists.
Author: Rex Y. Wang
Publisher:
ISBN: 9780471501855
Category :
Languages : en
Pages : 370
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Book Description
Author: Joseph R. Reeve
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 496
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Book Description
This volume reflects the interest in cholecystokinin, not only among gastroenterologists but also among neuroscientists and the drug industry, due to findings concerning the cholecystokinin antagonist and its effects on the central nervous system regarding satiety, panic attacks and depression.
Author: Colin T. Dourish
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 588
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Book Description
This volume summarizes the most recent research on CCK, and has contributions from the leading experts in the field. Prominence is given to important advances made using novel CCK receptor antagonists, which have been valuable research tools and may prove to be useful therapies.
Author: John Hughes (Ph. D.)
Publisher:
ISBN:
Category : Brain chemistry
Languages : en
Pages : 264
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Book Description
Author: Xi-Qin Ding
Publisher:
ISBN:
Category : Cholecystokinin
Languages : en
Pages : 164
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Book Description
Author: Gerbail T. Krishnamurthy
Publisher: Springer Science & Business Media
ISBN: 3642006485
Category : Medical
Languages : en
Pages : 365
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Book Description
Since the publication of the first edition of Nuclear Hepatology almost 10 years ago, new advances have taken place, both in our understanding of liver pathophysiology and various imaging modalities. A unique feature of imaging of physiology is that it enables quanti- cation. Since liver physiology is complex, quantification has been a challenge. Many p- lications in the past have often included quantification based on home-made software not available for others. Thus, the comparison of results from one center to another becomes difficult, if not impossible. The second edition of Nuclear Hepatology addresses these issues. Sophisticated software for liver and gallbladder function has been tested and va- dated through many of our previous publications. Now that software is FDA approved and available for others through a commercial company, it is hoped that future publications of imaging of liver and gallbladder physiology would routinely include quantification. Although the function of the hepatocyte is complex, it can be broadly divided into two main categories, substrate uptake at the basolateral border and intracellular transit prior to excretion into the canaliculi. The earliest manifestation of hepatocellular injury occurs in the form of prolongation of the intracellular transit time, which occurs long before the disruption of the basolateral border with subsequent rupture and death. The liver enzymes are released into circulation after the death of the hepatocyte.
