Cellular Nanomachines

Cellular Nanomachines PDF Author: Bhanu P. Jena
Publisher: Springer Nature
ISBN: 3030444961
Category : Science
Languages : en
Pages : 118

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Book Description
In this book, the major paradigm-shifting discoveries made in the past century on key cellular nanomachines are described in great detail: their complex yet precise and elegant design and function, as well as the diseases linked to their dysfunction and the therapeutic approaches to overcome them. The major focus of this book is the “porosome” nanomachine, the universal secretory portal in cells. This is an ideal book for students, researchers, and professionals in the fields of nanoscience and nanotechnology.

Cellular Nanomachines

Cellular Nanomachines PDF Author: Bhanu P. Jena
Publisher: Springer Nature
ISBN: 3030444961
Category : Science
Languages : en
Pages : 118

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Book Description
In this book, the major paradigm-shifting discoveries made in the past century on key cellular nanomachines are described in great detail: their complex yet precise and elegant design and function, as well as the diseases linked to their dysfunction and the therapeutic approaches to overcome them. The major focus of this book is the “porosome” nanomachine, the universal secretory portal in cells. This is an ideal book for students, researchers, and professionals in the fields of nanoscience and nanotechnology.

Biophysics and Nanotechnology of Ion Channels

Biophysics and Nanotechnology of Ion Channels PDF Author: Mohammad Ashrafuzzaman
Publisher: CRC Press
ISBN: 1000451593
Category : Science
Languages : en
Pages : 318

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Book Description
This book provides a comprehensive review of the biophysics and nanotechnology of ion channels. It details the biological and physiological entities of ion channels in cells and addresses various physical perspectives of ion channel structures and functions. Naturally inbuilt and artificial applicable nanotechnologies of ion channels are modelled and explored. It discusses various methods that can be utilized toward understanding ion channel-based cellular diseases. Physical, biochemical, biomedical, and bioinformatics techniques are taken into consideration to enable the development of strategies to address therapeutic drug discovery and delivery. This book will be of interest to advanced undergraduate and graduate students in biophysics and related biomedical sciences in addition to researchers in the field and industry. Features: Provides a stimulating introduction to the structures and functions of ion channels of biological cell membranes and discusses the biophysics of ion channels in condensed matter state and physiological condition Addresses natural processes and nanotechnology opportunities for their purposeful manipulation Lays the groundwork for vitally important medical advances Mohammad Ashrafuzzaman, a biophysicist and condensed matter scientist, is passionate about investigating biological and biochemical processes utilizing the principles and techniques of physics. He is an associate professor at King Saud University’s Biochemistry Department of College of Science, Riyadh, Saudi Arabia, the co-founder of MDT Canada Inc., and the founder of Child Life Development Institute, Edmonton, Canada. He also authored Nanoscale Biophysics of the Cell and Membrane Biophysics.

Nano Comes to Life

Nano Comes to Life PDF Author: Sonia Contera
Publisher: Princeton University Press
ISBN: 0691206449
Category : Medical
Languages : en
Pages : 232

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Book Description
"Increasingly, scientists are gaining control over matter at the nanometer scale. Spearheaded by physical scientists operating at the interfaces of physics and biology (such as the author herself), advances in nanoscience and technology are transforming how we think about life and treat human health. This is due to a convergence of size. To do medicine, one must understand and be able to reach the nanoscale environment of healthy cells in tissues and organs, as well as other nano-sized building blocks that constitute a living organism, such as proteins and DNA. The ground-breaking advances being made at the frontiers of nanoscience and -technology, specifically in the areas of biology and medicine, are the subject of this short, popular-level book. Chapter 1 describes how nanotechnology and quantitative methods in biology are progressively being deployed to embrace life in all its multiscale, hierarchical intricacy and multiplicity. Chapters 2 through 4 review how bioinspired and biomimetic nanostructures and nanomachines are being created and integrated into strategies aimed at solving specific medical problems. In particular, Chapter 2 summarizes how scientists are seeking to build artificial nanostructures using both biological molecules and the organizational principles of biology. Chapter 3 gives an account of how nanotechnology is being used to develop drug-delivery strategies that specifically target cancer cells and tumors to improve the efficacy of current cancer chemotherapies. Chapter 4 reviews the science of one of the most potentially transformative scientific fields: tissue engineering. In a concluding chapter (Chapter 5), Contera reviews how nanotechnology, biology, and medicine will continue fusing with other sciences and technologies - incorporating more mathematical and computational modelling, as well as AI and robotics. Nanoscale devices will be used to learn biology; and biology will be used to inspire increasingly sophisticated "transmaterial" devices that mimic some of the characteristics of biology and incorporate new features that are not available in the biological world. The effects on human health and longevity will be profound. In a more personal epilogue, Contera describes the crossroads at which we find ourselves. Accessing our own biology evokes a mixture of possibility and dread. However, Contera maintains that we can create a positive transmaterial world for the benefit of humankind, and she describes ways in which scientists are proactively engaging with the public, politicians, industry, and entrepreneurs, as well as the media and the arts, to communicate the power and risks of new advances and to influence the ways in which new technologies will affect our future"--

Thinking in Complexity

Thinking in Complexity PDF Author: Klaus Mainzer
Publisher: Springer Science & Business Media
ISBN: 3540722289
Category : Science
Languages : en
Pages : 491

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Book Description
This new edition also treats smart materials and artificial life. A new chapter on information and computational dynamics takes up many recent discussions in the community.

Cellular Transplantation

Cellular Transplantation PDF Author: Craig Halberstadt
Publisher: Elsevier
ISBN: 0080469043
Category : Science
Languages : en
Pages : 699

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Book Description
There have been tremendous strides in cellular transplantation in recent years, leading to accepted practice for the treatment of certain diseases, and use for many others in trial phases. The long history of cellular transplantation, or the transfer of cells from one organism or region of the body to another, has been revolutionized by advances in stem cell research, as well as developments in gene therapy. Cellular Transplants: From Lab to Clinic provides a thorough foundation of the basic science underpinning this exciting field, expert overviews of the state-of-the-art, and detailed description of clinical success stories to date, as well as insights into the road ahead. As highlighted by this timely and authoritative survey, scale-up technologies and whole organ transplantation are among the hurdles representing the next frontier. The contents are organized into four main sections, with the first covering basic biology, including transplant immunology, the use of immunosuppressive drugs, stem cell biology, and the development of donor animals for transplantation. The next part looks at peripheral and reconstructive applications, followed by a section devoted to transplantation for diseases of the central nervous system. The last part presents efforts to address the key challenges ahead, such as identifying novel transplantable cells and integrating biomaterials and nanotechnology with cell matrices. - Provides detailed description of clinical trials in cell transplantation - Review of current therapeutic approaches - Coverage of the broad range of diseases addressed by cell therapeutics - Discussion of stem cell biology and its role in transplantation

Comprehensive Nanoscience and Nanotechnology

Comprehensive Nanoscience and Nanotechnology PDF Author:
Publisher: Academic Press
ISBN: 012812296X
Category : Technology & Engineering
Languages : en
Pages : 1881

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Book Description
Comprehensive Nanoscience and Technology, Second Edition, Five Volume Set allows researchers to navigate a very diverse, interdisciplinary and rapidly-changing field with up-to-date, comprehensive and authoritative coverage of every aspect of modern nanoscience and nanotechnology. Presents new chapters on the latest developments in the field Covers topics not discussed to this degree of detail in other works, such as biological devices and applications of nanotechnology Compiled and written by top international authorities in the field

Atomic Force Microscopy in Molecular and Cell Biology

Atomic Force Microscopy in Molecular and Cell Biology PDF Author: Jiye Cai
Publisher: Springer
ISBN: 9811315108
Category : Science
Languages : en
Pages : 244

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Book Description
The book addresses new achievements in AFM instruments – e.g. higher speed and higher resolution – and how AFM is being combined with other new methods like NSOM, STED, STORM, PALM, and Raman. This book explores the latest advances in atomic force microscopy and related techniques in molecular and cell biology. Atomic force microscopy (AFM) can be used to detect the superstructures of the cell membrane, cell morphology, cell skeletons and their mechanical properties. Opening up new fields of in-situ dynamic study for living cells, enzymatic reactions, fibril growth and biomedical research, these combined techniques will yield valuable new insights into molecule and cell biology. This book offers a valuable resource for students and researchers in the fields of biochemistry, cell research and chemistry etc.

Nanotechnology in Biology and Medicine

Nanotechnology in Biology and Medicine PDF Author: Tuan Vo-Dinh
Publisher: CRC Press
ISBN: 1439893799
Category : Science
Languages : en
Pages : 763

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Book Description
The second edition of Nanotechnology in Biology and Medicine is intended to serve as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of nanotechnology in life sciences. This technology, which is on the scale of molecules, has enabled the development of devices smaller and more efficient than anything currently available. To understand complex biological nanosystems at the cellular level, we urgently need to develop a next-generation nanotechnology tool kit. It is believed that the new advances in genetic engineering, genomics, proteomics, medicine, and biotechnology will depend on our mastering of nanotechnology in the coming decades. The integration of nanotechnology, material sciences, molecular biology, and medicine opens the possibility of detecting and manipulating atoms and molecules using nanodevices, which have the potential for a wide variety of biological research topics and medical uses at the cellular level. This book presents the most recent scientific and technological advances of nanotechnology for use in biology and medicine. Each chapter provides introductory material with an overview of the topic of interest; a description of methods, protocols, instrumentation, and applications; and a collection of published data with an extensive list of references for further details. The goal of this book is to provide a comprehensive overview of the most recent advances in instrumentation, methods, and applications in areas of nanobiotechnology, integrating interdisciplinary research and development of interest to scientists, engineers, manufacturers, teachers, and students.

Re-Creating Nature

Re-Creating Nature PDF Author: James T. Bradley
Publisher: University Alabama Press
ISBN: 0817320296
Category : Science
Languages : en
Pages : 404

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Book Description
An exploration of the moral and ethical implications of new biotechnologies Many of the ethical issues raised by new technologies have not been widely examined, discussed, or indeed settled. For example, robotics technology challenges the notion of personhood. Should a robot, capable of making what humans would call ethical decisions, be held responsible for those decisions and the resultant actions? Should society reward and punish robots in the same way that it does humans? Likewise, issues of safety, environmental concerns, and distributive justice arise with the increasing acceptance of genetically modified organisms (GMOs) in food production nanotechnology in engineering and medicine, and human gene therapy and enhancement. The problem of dual-use—when a technology can be used both to benefit and to harm—exists with virtually all new technologies but is central in the context of emerging 21st century technologies ranging from artificial intelligence and robotics to human gene-editing and brain-computer interfacing. In Re-Creating Nature: Science, Technology, and Human Values in the Twenty-First Century, James T. Bradley addresses emerging biotechnologies with prodigious potential to benefit humankind but that are also fraught with ethical consequences. Some actually possess the power to directly alter the evolution of life on earth including human. Specifically, these topics include stem cells, synthetic biology, GMOs in agriculture, nanotechnology, bioterrorism, CRISPR gene-editing technology, three-parent babies, robotics and roboethics, artificial intelligence, and human brain research and neurotechnologies. Offering clear explanations of these various technologies, a pragmatic presentation of the conundrums involved, and questions that illuminate hypothetical situations, Bradley guides discussions of these and other thorny issues resulting from the development of new biotechnologies. He also highlights the responsibilities of scientists to conduct research in an ethical manner and the responsibilities of nonscientists to become “science literate” in the twenty-first century.

The Edge of Evolution

The Edge of Evolution PDF Author: Michael J. Behe
Publisher: Simon and Schuster
ISBN: 0743296222
Category : Religion
Languages : en
Pages : 339

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Book Description
The author of Darwin's Black Box draws on new findings in genetics to pose an argument for intelligent design that refutes Darwinian beliefs about evolution while offering alternative analyses of such factors as disease, random mutations, and the human struggle for survival. Reprint. 40,000 first printing.