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Author: Lorraine Hache
Publisher:
ISBN: 9781478214564
Category :
Languages : en
Pages : 148
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Book Description
Your source of beauty is at the cellular level. "Cellular Makeover" deals with much more than just appearance, as appearance as well as the elements and gravity are what pay their toll over time. But we will be dealing with the actions and emotions that in turn have caused a certain amount of havoc within the body, deep within the systems and their harmonious function one with the other. Rejuvenation is at the cellular level and mirrors itself into one's face. The body's tissue, much more evident in the facial features, is a holographic image of the general state of health of the body. With the latest Scientific knowledge from the West and the ancient wisdom from the East, this book guides you through the latest knowledge on how to evaluate, how to prevent and how to nurture your cells to give you that absolute Cellular Makeover" which is your true source of beauty.
Author: Lorraine Hache
Publisher:
ISBN: 9781478214564
Category :
Languages : en
Pages : 148
Get Book
Book Description
Your source of beauty is at the cellular level. "Cellular Makeover" deals with much more than just appearance, as appearance as well as the elements and gravity are what pay their toll over time. But we will be dealing with the actions and emotions that in turn have caused a certain amount of havoc within the body, deep within the systems and their harmonious function one with the other. Rejuvenation is at the cellular level and mirrors itself into one's face. The body's tissue, much more evident in the facial features, is a holographic image of the general state of health of the body. With the latest Scientific knowledge from the West and the ancient wisdom from the East, this book guides you through the latest knowledge on how to evaluate, how to prevent and how to nurture your cells to give you that absolute Cellular Makeover" which is your true source of beauty.
Author: Zhenyu Yue
Publisher: World Scientific
ISBN: 981444068X
Category : Science
Languages : en
Pages : 440
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Book Description
What is autophagy? Why would neurons digest parts of themselves through autophagy? How can autophagy save the lives of cells under some conditions, but act as an accomplice to cell death in others? By what mechanisms are autophagy-related processes dysregulated in neurological diseases, and are there therapeutic strategies to correct or compensate for their dysfunction? This book provides an expert view of major concepts in autophagy research with a focus on autophagy in neurons. Experimental evidence for evolutionarily conserved and specialized regulatory mechanisms for autophagy in the mammalian nervous system will be presented, including recent data on braking mechanisms. Areas of intersection with cell death, the ubiquitin-proteasome system, chaperone-mediated autophagy, and the endocytic pathway will be reviewed, along with emerging areas of mitochondrial autophagy (mitophagy) and the autophagic regulation of neuritic/synaptic processes. Advances in delineating mechanisms by which autophagy is involved in the pathophysiology of neurological disorders, including Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, ischemia/hypoxia and lysosomal storage diseases, will be discussed along with current drug development strategies targeting autophagy. Contents:Neuronal Autophagy: Cellular Process and Regulation:The Cellular Process of Autophagy and Control of Autophagy in Neurons (Nicole C McKnight, Noboru Mizushima and Zhenyu Yue)Autophagosome Maturation, Endocytosis and Neurodegenerative Disease (Ai Yamamoto and Anne Simonsen)Cross-Talk Between the Ubiquitin-Proteasome System and Macroautophagy (Serhiy Pankiv and Terje Johansen)Chaperone-Mediated Autophagy (CMA) in Neurons (Maria Xilouri, Hsiao-Yu Peng and Leonidas Stefanis)Maintaining Autophagic Balance: A Role for Brakes (Salvatore J Cherra, III and Charleen T Chu)Autophagy and Neurological Diseases:Autophagy and Its Cross-Talk with Cell Death in Neural Development (Sabrina Di Bartolomeo and Francesco Cecconi)Autophagy in the Retina: Development, Physiology and Pathology (Patricia Boya)Genetic Mouse Models for Elucidation of Autophagy-Lysosomal Systems in Neurons Under Physiologic and Pathologic Conditions (Masaaki Komatsu, Masato Koike, Yoshinobu Ichimura and Yasuo Uchiyama)Autophagy in Amyotrophic Lateral Sclerosis (Jozsef Gal and Haining Zhu)Autophagy Failure in Alzheimer's Disease and Lysosomal Storage Disorders: A Common Pathway to Neurodegeneration? (Devin M Wolfe and Ralph Nixon)Autophagy in Huntington's and Parkinson's Diseases: Pathogenic Mechanism and Therapeutic Potentials (Junghyun Lim, Lauren G Friedman, Nicole C McKnight and Zhenyu Yue)Metabolism, Autophagy and Neurodegeneration (W Haung Yu and Karen E Duff)The Potential of Autophagy Regulation in the Treatment of Neurodegenerative Diseases (Ashley R Winslow, Zeyn W Green-Thompson and David C Rubinsztein)Lysosome Storage Disorders on the Brain: The Autophagy-Lysosome Pathway Contributes to Disease Pathophysiology and May be Utilized for Therapeutic Benefit (John J Shacka)Specialized Autophagy: The New Frontier:Autophagy — Roles in Synaptic Structure and Function (Daniela Hernandez and David Sulzer)Neuronal Mitochondrial Transport and Turnover via Mitophagy (Zu-Hang Sheng and Charleen T Chu)Role of Autophagy in Neurite Degeneration In Vitro (Yi Yang, Xiaoxiang Zheng and Tatsuro Koike) Readership: Neurologists (clinical), molecular biologists (scientists), and college students. Keywords:Autophagy;Neurons;Neurodegeneration;Cell Death;Disease;Neuropathology;Neurological Disorders;Autophagosomes;Lysosomes;Degradation;Axons;Mitochondria;Chaperone Proteins;Alzheimer's Disease;Parkinson's Disease;Huntington's Disease;Protein AggregationKey Features:Collates the most recent research on autophagy regulation and critically examines the relevance of specific mechanisms to disease in light of unique aspects of neuronal cell biologyCovers newer knowledge of general autophagy processes, reviews the state of the art on specific aspects of autophagy regulation in neurons, and discusses the role of autophagy in neurodegenerative diseaseThe co-editors and contributing authors for each of the chapters are all experts, including some of the most influential figures in autophagy research and neurodegeneration
Author: P. Michael Conn
Publisher: Academic Press
ISBN: 0123851165
Category : Cell physiology
Languages : en
Pages : 428
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Book Description
This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights. This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological ins.
Author: P. Michael Conn
Publisher: Academic Press
ISBN: 0123851173
Category : Science
Languages : en
Pages : 432
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Book Description
This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights. This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights.
Author: Uddin, Md. Sahab
Publisher: IGI Global
ISBN: 1799813185
Category : Medical
Languages : en
Pages : 515
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Book Description
Protein misfolding and aggregation are hallmarks of several neurodegenerative proteinopathies. Though multiple factors like aging, oxidative stress, mitochondrial dysfunction, proteotoxic insults, genetic inconsistency, etc. are responsible for the dysfunction of the neuronal protein quality control system, targeting protein quality control has become an auspicious approach to halt the propagation of neurodegeneration. Quality Control of Cellular Protein in Neurodegenerative Disorders provides diverse aspects exploring the role of the protein quality control in neurodegenerative disorders and potential therapeutic strategies to combat the development and propagation of neurodegeneration. Featuring coverage on a broad range of topics such as molecular chaperones, protein misfolding, and stress signaling, this book is ideally designed for neurobiologists, neuropsychologists, neurophysiologists, medical professionals, neuropathologists, researchers, academicians, students, and practitioners engaged in studies of the protein quality control system in neuronal cells.
Author: Borko Furht
Publisher: CRC Press
ISBN: 0203011694
Category : Computers
Languages : en
Pages : 632
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Book Description
Wireless applications are definitely the next big thing in communications. Millions of people around the world use the Internet every day - to stay in touch with remote locations, follow the stock market, keep up with the news, check the weather, make travel plans, conduct business, shop, entertain themselves, and learn. The logical next step is th
Author:
Publisher: Elsevier
ISBN: 0123864577
Category : Medical
Languages : en
Pages : 5000
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Book Description
Pathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human Organ Systems Molecular Pathology/Basic Mechanisms of Diseases Animal Models/Other Model Systems Experimental Pathology Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. Reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting Articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of "Normal" and "Disease" anatomy and histology images Fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutions
Author: Vincent C. Giampapa
Publisher: Turner Publishing Company
ISBN: 1591205441
Category : Health & Fitness
Languages : en
Pages : 168
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Book Description
This book shows readers how they can personally direct and monitor their own health and become proactive in optimizing their quality of life. Thanks to the latest advances in genetic science, one no longer has to be a victim of genetic inheritance.
Author: Denis Martinvalet
Publisher: Frontiers Media SA
ISBN: 2889745287
Category : Medical
Languages : en
Pages : 176
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Book Description
Author: M. A. Hayat
Publisher: Academic Press
ISBN: 0128094281
Category : Medical
Languages : en
Pages : 370
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Book Description
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 10 offer a valuable guide to both cellular processes, while encouraging researchers to explore their potentially important connections. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. This is the tenth volume of the multivolume series that discusses, in detail, almost all aspects of the autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. Volume 10 of the Autophagy series discusses the role of a novel binuclear palladacycle complex that inhibits melanoma growth through apoptosis and autophagy. Presents the most advanced information regarding the role of the autophagic system in life and death Contains a direct focus on the role of a novel binuclear palladacycle complex that inhibits melanoma growth Introduces new, more effective therapeutic strategies in the development of targeted drugs and programmed cell death, providing information that will aid in preventing detrimental inflammation States recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities Edited work with chapters authored by leaders in the field from around the globe—the broadest, most expert coverage available
