Cell Polarity and Subcellular RNA Localization

Cell Polarity and Subcellular RNA Localization PDF Author: Dietmar Richter
Publisher: Springer Science & Business Media
ISBN: 3540400257
Category : Science
Languages : en
Pages : 248

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Book Description
Selective cytoplasmic organelle and protein targeting has long been thought to constitute the sole determinant of cell polarity and complexity. This view has been changed, however, by the discovery of differential subcellular RNA distribution patterns. Over the past decade it has become clear that selective mRNA sorting and translation contributes to an accumulation of cognate proteins at discrete cellular sites. In this book, various systems are discussed (e.g. Xenopus oocytes, mammalian brain, invertebrate nervous system) in terms of RNA trafficking, RNA-targeting sequences (cis-elements) and RNA-transporting proteins (trans-factors), activity-dependent translational regulation and the significance of the cytoskeleton for neuronal function and plasticity. It also discusses nucleocytoplasmic export of mRNA and viral RNA as another example of subcellular RNA kinesis.

Cell Polarity and Subcellular RNA Localization

Cell Polarity and Subcellular RNA Localization PDF Author: Dietmar Richter
Publisher: Springer Science & Business Media
ISBN: 3540400257
Category : Science
Languages : en
Pages : 248

Get Book Here

Book Description
Selective cytoplasmic organelle and protein targeting has long been thought to constitute the sole determinant of cell polarity and complexity. This view has been changed, however, by the discovery of differential subcellular RNA distribution patterns. Over the past decade it has become clear that selective mRNA sorting and translation contributes to an accumulation of cognate proteins at discrete cellular sites. In this book, various systems are discussed (e.g. Xenopus oocytes, mammalian brain, invertebrate nervous system) in terms of RNA trafficking, RNA-targeting sequences (cis-elements) and RNA-transporting proteins (trans-factors), activity-dependent translational regulation and the significance of the cytoskeleton for neuronal function and plasticity. It also discusses nucleocytoplasmic export of mRNA and viral RNA as another example of subcellular RNA kinesis.

Localized RNAs

Localized RNAs PDF Author: Howard D. Lipshitz
Publisher: R G Landes Company
ISBN: 9781570592768
Category : Science
Languages : en
Pages : 322

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Book Description


Cell Polarity and Subcellular RNA Localization

Cell Polarity and Subcellular RNA Localization PDF Author: Dietmar Richter
Publisher:
ISBN: 9783642535697
Category :
Languages : en
Pages : 236

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Book Description


Cell Polarity in Development and Disease

Cell Polarity in Development and Disease PDF Author: Douglas W Houston
Publisher: Academic Press
ISBN: 0128125918
Category : Science
Languages : en
Pages : 238

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Book Description
Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting cell polarity for translational medical research. - Provides basic science understanding of cell polarity disease and development - Covers diseases affecting polarized epithelial tissues in the lung and kidney, also covering the progression of cancer - Includes historical context of cell polarity research for potential future breakthroughs

Oocytes

Oocytes PDF Author: Malgorzata Kloc
Publisher: Springer
ISBN: 331960855X
Category : Science
Languages : en
Pages : 505

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Book Description
This book combines the most recent knowledge on the maternal, i.e. oocyte/egg-specific, molecules and processes. The volume covers the most recent advances in a plethora of subjects such as: maternal transfer of immunity, localized RNAs functions and mechanisms of RNA localization, transcriptional repression of maternal messages, maternal inheritance and maternal role of CRISPR/Cas9-based genome editing, chromatin remodeling and epigenetic modifications, maternal function of nucleosomes, maternal mitochondria and energy supply, role of bacterial symbionts and their maternal transmission, acquisition of oocyte polarity and evolution of maternal effect genes, germ plasm and oosome origin and functions, mechanisms of oocyte activation and soma germ cells communication. Currently, no other book on the market combines such a comprehensive list of subjects in one volume. Moreover, the information provided is a cross-section through oocytes from various invertebrate and vertebrate species, which is another unique feature of this book. The readers, therefore, get a completely new and invaluable perspective on all covered subjects.

Polarity in Plants

Polarity in Plants PDF Author: K. Lindsey
Publisher: John Wiley & Sons
ISBN: 9780849323447
Category : Science
Languages : en
Pages : 368

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Book Description
The establishment of polarity is a fundamental feature in eukaryotic development. Polarity in Plants provides an account of current research into the mechanisms by which polarity is generated at the level of the cell, organ and organism in plants, drawing especially on recent work with model organisms. The emphasis is on the use of the techniques of molecular genetics to dissect molecular mechanisms. This is the first volume to bring together the diverse aspects of polarity in plant development.

Cell Polarity 1

Cell Polarity 1 PDF Author: Klaus Ebnet
Publisher: Springer
ISBN: 3319144634
Category : Science
Languages : en
Pages : 396

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Book Description
This work provides a state-of-the art overview on the most relevant aspects of cell polarity. Volume 1 addresses cell polarity and cell migration (front-rear polarity), cell polarity and barrier formation (apico-basal polarity) and neuronal polarity. It particularly focuses on cell polarity at the molecular level and the underlying molecular mechanisms. It also elaborates the common principles and mechanisms that regulate cellular polarization in different cell types and contexts. Both volumes are intended for professors, group leaders and researchers in cell biology as well as medical professionals in the fields of anatomy, cell biology, physiology, pathology and tumor biology.

Molecular Kinesis in Cellular Function and Plasticity

Molecular Kinesis in Cellular Function and Plasticity PDF Author: Proceedings of the National Academy of Sciences
Publisher: National Academies Press
ISBN: 0309074258
Category : Science
Languages : en
Pages : 116

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Book Description


Plasticity of cell polarity across scales in development and disease

Plasticity of cell polarity across scales in development and disease PDF Author: Eurico Morais-de-Sá
Publisher: Frontiers Media SA
ISBN: 283253712X
Category : Science
Languages : en
Pages : 152

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Book Description


The Nucleolus

The Nucleolus PDF Author: Mark O. J. Olson
Publisher: Springer Science & Business Media
ISBN: 1461405149
Category : Science
Languages : en
Pages : 434

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Book Description
Within the past two decades, extraordinary new functions for the nucleolus have begun to appear, giving the field a new vitality and generating renewed excitement and interest. These new discoveries include both newly-discovered functions and aspects of its conventional role. The Nucleolus is divided into three parts: nucleolar structure and organization, the role of the nucleolus in ribosome biogenesis, and novel functions of the nucleolus.