Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0

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Author: John Lloyd Hall
Publisher: Longman Publishing Group
ISBN:
Category : Science
Languages : en
Pages : 140

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Author: Wilfred Stein
Publisher: Elsevier
ISBN: 0323143202
Category : Science
Languages : en
Pages : 704

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Book Description
Transport and Diffusion across Cell Membranes is a comprehensive treatment of the transport and diffusion of molecules and ions across cell membranes. This book shows that the same kinetic equations (with appropriate modification) can describe all the specialized membrane transport systems: the pores, the carriers, and the two classes of pumps. The kinetic formalism is developed step by step and the features that make a system effective in carrying out its biological role are highlighted. This book is organized into six chapters and begins with an introduction to the structure and dynamics of cell membranes, followed by a discussion on how the membrane acts as a barrier to the transmembrane diffusion of molecules and ions. The following chapters focus on the role of the membrane's protein components in facilitating transmembrane diffusion of specific molecules and ions, measurements of diffusion through pores and the kinetics of diffusion, and the structure of such pores and their biological regulation. This book methodically introduces the reader to the carriers of cell membranes, the kinetics of facilitated diffusion, and cotransport systems. The primary active transport systems are considered, emphasizing the pumping of an ion (sodium, potassium, calcium, or proton) against its electrochemical gradient during the coupled progress of a chemical reaction while a conformational change of the pump enzyme takes place. This book is of interest to advanced undergraduate students, as well as to graduate students and researchers in biochemistry, physiology, pharmacology, and biophysics.

Author: E. Edward Bittar
Publisher: John Wiley & Sons
ISBN:
Category : Science
Languages : en
Pages : 512

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Author: G. Giebisch
Publisher: Springer Science & Business Media
ISBN: 3642463649
Category : Medical
Languages : en
Pages : 471

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Book Description
The contributions of this volume are concerned with transport phenomena in multimembrane systems and in simple epithelia. In addition to the very substan tial progress that has been made in the area of transport of fluid and solutes across artifical model membranes in vitro and across simple symmetrical cell membranes, much has been learned from studies of transport phenomena in multi membrane systems of higher complexity to be reviewed in this volume. It should be recalled that many of the fundamental conceptual and methodological problems of transport physiology have been successfully approached and defin ed by studying simple epithelia in vitro, and that the direction that research has taken has been affected in a major way by the cellular transport models that have evolved from this approach. Since then striking progress has been made in several areas. Not only have we been witnessing a keen and productive interest in the realtionship between fine structure and transport behavior in multimem brane systems but significant advancements have also been made in defining individual active and passive transport operations, in analysing cell ion activities and transport pools, and in describing the differences in transport functions that underly the membrane asymmetry and cell polarization of cells subserving di rectional transport.

Author: Hans T. Clarke
Publisher: Academic Press
ISBN: 1483275779
Category : Medical
Languages : en
Pages : 311

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Book Description
Ion Transport Across Membranes focuses on the process of ion transport across cell membranes, including ion permeability, biological membranes, and thermodynamics. The selection first offers information on ion transport across biological membranes and electrical processes in nerve conduction. Topics include diffusion through biological membranes, active transport, voltage-current relations in the membrane, myelinated nerve fibers, and sequence of events in a nerve impulse. The text then ponders on generation of bioelectric potentials and optical observations on the interaction between acetyl cholinesterase and its substrate. The publication takes a look at ion permeability of the red cell and renal mechanisms of electrolyte transport. The text also tackles membrane permeability and electrical potential; transport of ions through biological membranes from the standpoint of irreversible thermodynamics; and electrochemical studies with model membranes. Topics include membranes of high electrochemical activity in physicochemical and model studies of biological interest and membrane resting potential. The selection is a vital reference for readers interested in ion transport across membranes.

Author: Thomas E. Andreoli
Publisher: Springer Science & Business Media
ISBN: 1468454048
Category : Medical
Languages : en
Pages : 399

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Book Description
Membrane Transport Processes in Organized Systems is a softcover book containing portions of Physiology of Membrane Disorders (Second Edition). The parent volume contains six major sections. This text encompasses the fourth and fifth sections: Transport Events in Single Cells and Transport in Epithelia: Vectorial Transport through Parallel Arrays. We hope that this smaller volume, which deals with transport processes in single cells and in organized epithelia, will be helpful to individuals interested in general physiology, transport in single cells and epithelia, and the methods for studying those transport processes. THOMAS E. ANDREOLI JOSEPH F. HOFFMAN DARRELL D. FANESTIL STANLEY G. SCHULTZ Vll Preface to the Second Edition The second edition of Physiology of Membrane Disorders represents an extensive revision and a considerable expansion ofthe first edition . Yet the purpose of the second edition is identical to that of its predecessor, namely, to provide a rational analysis of membrane transport processes in individual membranes, cells, tissues, and organs, which in tum serves as a frame of reference for rationalizing disorders in which derangements of membrane transport processes play a cardinal role in the clinical expression of disease. As in the first edition, this book is divided into a number of individual, but closely related, sections. Part V represents a new section where the problem of transport across epithelia is treated in some detail. Finally, Part VI, which analyzes clinical derangements, has been enlarged appreciably.

Author: Alexander Beaumont Hope
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 140

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Author: Thomas E. Andreoli
Publisher: Springer Science & Business Media
ISBN: 1461319439
Category : Medical
Languages : en
Pages : 397

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Book Description
Membrane Physiology (Second Edition) is a soft-cover book containing portions of Physiology of Membrane Disorders (Second Edition). The parent volume contains six major sections. This text encompasses the first three sections: The Nature of Biological Membranes, Methods for Studying Membranes, and General Problems in Membrane Biology. We hope that this smaller volume will be helpful to individuals interested in general physiology and the methods for studying general physiology. THOMAS E. ANDREOLI JOSEPH F. HOFFMAN DARRELL D. FANESTIL STANLEY G. SCHULTZ vii Preface to the Second Edition The second edition of Physiology of Membrane Disorders represents an extensive revision and a considerable expansion of the first edition. Yet the purpose of the second edition is identical to that of its predecessor, namely, to provide a rational analysis of membrane transport processes in individual membranes, cells, tissues, and organs, which in tum serves as a frame of reference for rationalizing disorders in which derangements of membrane transport processes playa cardinal role in the clinical expression of disease. As in the first edition, this book is divided into a number of individual, but closely related, sections. Part V represents a new section where the problem of transport across epithelia is treated in some detail. Finally, Part VI, which analyzes clinical derangements, has been enlarged appreciably.

Author: Wilfred D. Stein
Publisher: Elsevier
ISBN: 0124165834
Category : Science
Languages : en
Pages : 423

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Book Description
An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered. Provides an introduction to the properties of transport proteins: channels, carriers, and pumps Presents up-to-date information on the structure of transport proteins and on their function and regulation Includes introductions to transport kinetics and to the cloning of genes that code transport proteins Furnishes a link between the experimental basis of the subject and theoretical model building