Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems

Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems PDF Author: Antonio Giordano
Publisher: Springer Science & Business Media
ISBN: 1603271538
Category : Medical
Languages : en
Pages : 259

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Book Description
Complex physiopathological relationships have been proven to exist between two of the body’s most vital organs; the brain and the heart. In Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems Antonio Giordano, Umberto Galderisi and a panel of the most respected authorities in their field offer an in-depth analysis of the differentiation process in two systems that have profound relationships with one another. The text looks at several aspects of the cardiovascular and nervous systems from a new point of view, describing the differences and similarities in their differentiation pathways with an emphasis on the role of cell cycle regulation and cell differentiation. Topics discussed include neurogenesis in the central nervous system, neural stem cells, and the basic-helix-loop-helix transcription factors in neural differentiation. Ground-breaking and authoritative, Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems is a must have for all researchers in cardiovascular medicine and neuroscience and will prompt the scientific community to perceive cell cycle regulation and differentiation under a novel and more comprehensive light.

Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems

Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems PDF Author: Antonio Giordano
Publisher: Springer Science & Business Media
ISBN: 1603271538
Category : Medical
Languages : en
Pages : 259

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Book Description
Complex physiopathological relationships have been proven to exist between two of the body’s most vital organs; the brain and the heart. In Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems Antonio Giordano, Umberto Galderisi and a panel of the most respected authorities in their field offer an in-depth analysis of the differentiation process in two systems that have profound relationships with one another. The text looks at several aspects of the cardiovascular and nervous systems from a new point of view, describing the differences and similarities in their differentiation pathways with an emphasis on the role of cell cycle regulation and cell differentiation. Topics discussed include neurogenesis in the central nervous system, neural stem cells, and the basic-helix-loop-helix transcription factors in neural differentiation. Ground-breaking and authoritative, Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems is a must have for all researchers in cardiovascular medicine and neuroscience and will prompt the scientific community to perceive cell cycle regulation and differentiation under a novel and more comprehensive light.

Cell Cycle Regulation

Cell Cycle Regulation PDF Author: Philipp Kaldis
Publisher: Springer
ISBN: 9783642070938
Category : Science
Languages : en
Pages : 0

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Book Description
This book is a state-of-the-art summary of the latest achievements in cell cycle control research with an outlook on the effect of these findings on cancer research. The chapters are written by internationally leading experts in the field. They provide an updated view on how the cell cycle is regulated in vivo, and about the involvement of cell cycle regulators in cancer.

The Developing Human - E-Book

The Developing Human - E-Book PDF Author: Keith L. Moore
Publisher: Elsevier Health Sciences
ISBN: 0323611567
Category : Medical
Languages : en
Pages : 541

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Book Description
Extensively revised to incorporate recent research and current clinical practice, The Developing Human: Clinically Oriented Embryology, 11th Edition, covers all aspects of normal and abnormal embryonic and fetal development. In a clear, concise manner and lavishly illustrated throughout, this textbook is designed to successfully meet the needs of medical and health sciences profession students, as well as those in graduate programs. It provides an easy-to-digest, comprehensive review of what can be a complex and challenging subject. Guides readers month by month and stage by stage through embryo and fetal organ and systems development, using full-color photographs of clinical cases, relevant modern medical imaging, and numerous high-quality supportive figures. Includes many new 3D HD color rendered images of embryos and fetuses, as well as 3D reconstructions of whole embryos. Provides clinically-oriented problems for each chapter, with corresponding answers and explanations designed to facilitate discussion and learning. Features 18 exceptional color animations, now with narration, to help students as they explore and learn the complexity of embryological development. Provides the knowledge base needed for today’s examinations, including USMLE Step 1, as well as for future clinical practice. Thoroughly updated information includes new annotations on fundamental molecular events during embryogenesis, now required for many professional examinations. Includes enhanced clinical material in all chapters, with updated tables, Clinical Case highlights and a critical chapter on common signalling pathways during development that covers gene editing (CRISPR/Cas9), induced pluripotent stem cells (iPS), a revision of the sonic hedgehog signalling pathway; and more. Details how molecular biology has affected clinical practice, including techniques such as recumbent DNA technology and stem cell manipulation. Evolve Instructor site with a downloadable image bank is available to instructors through their Elsevier sales rep or via request at: https://evolve.elsevier.com

Global Epidemiology of Cancer

Global Epidemiology of Cancer PDF Author: Jahangir Moini
Publisher: John Wiley & Sons
ISBN: 1119817447
Category : Medical
Languages : en
Pages : 676

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Book Description
GLOBAL EPIDEMIOLOGY OF CANCER Cancer is the second highest cause of death in the United States, and a leading cause of death globally. Our goals are to discuss the global epidemiology of various cancers, with detailed information on their prevalence, incidence, and clinical considerations. Epidemiology is the key to understanding the mortality and morbidity of cancer, and how we can prevent, diagnose, and treat the disease. Prevention of cancer is essential for saving lives. Prevalence and incidence of cancer are key factors that each government and population must be aware of. Advances in the study of cancer occur on a regular basis, and this book provides the latest insights about relationships between the disease and stem cells, tumorigenesis, molecular interactions, pathways, channels, and immunity. Global Epidemiology of Cancer: Diagnosis and Treatment meets the needs of readers by providing current information about epidemiology (including molecular epidemiology), diagnosis, and treatment. Providing logical, step-by-step information on various cancers, this book consolidates all of the most up-to-date information and data from verified studies on all different types of cancers in the United States and throughout the world. Chapters are presented so that each includes an overview, clinical manifestations, epidemiology, pathophysiology, etiology and risk factors, diagnosis, treatment, prevention, and prognosis. Global Epidemiology of Cancer: Diagnosis and Treatment will be invaluable to graduate and postgraduate students, including medical students; nurses; physician assistants; residents in oncology; public health students and allied health students.

The Neural Crest

The Neural Crest PDF Author: Nicole Le Douarin
Publisher: Cambridge University Press
ISBN: 9780521620109
Category : Medical
Languages : en
Pages : 494

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Book Description
This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. This book is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.

Emerging research organisms in regenerative biology

Emerging research organisms in regenerative biology PDF Author: Igor Schneider
Publisher: Frontiers Media SA
ISBN: 2832516505
Category : Science
Languages : en
Pages : 162

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Book Description


Biomedical Index to PHS-supported Research

Biomedical Index to PHS-supported Research PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1398

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Book Description


Biomedical Index to PHS-supported Research: pt. A. Subject access A-H

Biomedical Index to PHS-supported Research: pt. A. Subject access A-H PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1398

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Book Description


Differentiation of Embryonic Stem Cells

Differentiation of Embryonic Stem Cells PDF Author:
Publisher: Academic Press
ISBN: 9780121822682
Category : Science
Languages : en
Pages : 509

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Book Description
This volume covers all aspects of embryonic stem cell differentiation, including mouse embryonic stem cells, mouse embryonic germ cells, monkey and human embryonic stem cells, and gene discovery. * Early commitment steps and generation of chimeric mice * Differentiation to mesoderm derivatives * Gene discovery by manipulation of mouse embryonic stem cells

Role of Stem Cells in Skeletal Muscle Development, Regeneration, Repair, Aging and Disease

Role of Stem Cells in Skeletal Muscle Development, Regeneration, Repair, Aging and Disease PDF Author: Pura Muñoz-Cánoves
Publisher: Frontiers Media SA
ISBN: 2889198669
Category : Biology (General)
Languages : en
Pages : 222

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Book Description
Adult stem cells are responsible for tissue regeneration and repair throughout life. Their quiescence or activation are tightly regulated by common signalling pathways that often recapitulate those happening during embryonic development, and thus it is important to understand their regulation not only in postnatal life, but also during foetal development. In this regard, skeletal muscle is an interesting tissue since it accounts for a large percentage of body mass (about 40%), it is highly amenable to intervention through exercise and it is also key in metabolic and physiological changes underlying frailty susceptibility in the elderly. While muscle-resident satellite cells are responsible for all myogenic activity in physiological conditions and become senescent in old age, other progenitor cells such as mesoangioblasts do seem to contribute to muscle regeneration and repair after tissue damage. Similarly, fibro-adipogenic precursor cells seem to be key in the aberrant response that fills up the space left from atrophied muscle mass and which ends up with a dysfunctional muscle having vast areas of fatty infiltration and fibrosis. The complex interplay between these stem/progenitor cell types and their niches in normal and pathological conditions throughout life are the subjects of intense investigation. This eBook highlights recent developments on the role of stem cells in skeletal muscle function, both in prenatal and postnatal life, and their regulation by transcriptional, post-transcriptional and epigenetic mechanisms. Additionally, it includes articles on interventions associated with exercise, pathological changes in neuromuscular diseases, and stem cell aging.