Cardiac Modeling: Aiming for Optimization of Therapy PDF Download
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Author: Javier Saiz
Publisher: Frontiers Media SA
ISBN: 2889662195
Category : Science
Languages : en
Pages : 248
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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author: Javier Saiz
Publisher: Frontiers Media SA
ISBN: 2889662195
Category : Science
Languages : en
Pages : 248
Get Book
Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author: Hui Yang
Publisher: Springer Nature
ISBN: 3031359526
Category : Business & Economics
Languages : en
Pages : 96
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Book Description
This book reviews the development of physics-based modeling and sensor-based data fusion for optimizing medical decision making in connection with spatiotemporal cardiovascular disease processes. To improve cardiac care services and patients’ quality of life, it is very important to detect heart diseases early and optimize medical decision making. This book introduces recent research advances in machine learning, physics-based modeling, and simulation optimization to fully exploit medical data and promote the data-driven and simulation-guided diagnosis and treatment of heart disease. Specifically, it focuses on three major topics: computer modeling of cardiovascular systems, physiological signal processing for disease diagnostics and prognostics, and simulation optimization in medical decision making. It provides a comprehensive overview of recent advances in personalized cardiac modeling by integrating physics-based knowledge of the cardiovascular system with machine learning and multi-source medical data. It also discusses the state-of-the-art in electrocardiogram (ECG) signal processing for the identification of disease-altered cardiac dynamics. Lastly, it introduces readers to the early steps of optimal decision making based on the integration of sensor-based learning and simulation optimization in the context of cardiac surgeries. This book will be of interest to researchers and scholars in the fields of biomedical engineering, systems engineering and operations research, as well as professionals working in the medical sciences.
Author: Alfio Quarteroni
Publisher: Cambridge University Press
ISBN: 1108570534
Category : Mathematics
Languages : en
Pages : 291
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Book Description
Mathematical and numerical modelling of the human cardiovascular system has attracted remarkable research interest due to its intrinsic mathematical difficulty and the increasing impact of cardiovascular diseases worldwide. This book addresses the two principal components of the cardiovascular system: arterial circulation and heart function. It systematically describes all aspects of the problem, stating the basic physical principles, analysing the associated mathematical models that comprise PDE and ODE systems, reviewing sound and efficient numerical methods for their approximation, and simulating both benchmark problems and clinically inspired problems. Mathematical modelling itself imposes tremendous challenges, due to the amazing complexity of the cardiovascular system and the need for computational methods that are stable, reliable and efficient. The final part is devoted to control and inverse problems, including parameter estimation, uncertainty quantification and the development of reduced-order models that are important when solving problems with high complexity, which would otherwise be out of reach.
Author: Efstratios N. Pistikopoulos
Publisher: John Wiley & Sons
ISBN: 1118965590
Category : Technology & Engineering
Languages : en
Pages : 326
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Book Description
Shows the newest developments in the field of multi-parametric model predictive control and optimization and their application for drug delivery systems This book is based on the Modelling, Control and Optimization of Biomedical Systems (MOBILE) project, which was created to derive intelligent computer model-based systems for optimization of biomedical drug delivery systems in the cases of diabetes, anaesthesia, and blood cancer. These systems can ensure reliable and fast calculation of the optimal drug dosage without the need for an online computer—while taking into account the specifics and constraints of the patient model, flexibility to adapt to changing patient characteristics and incorporation of the physician’s performance criteria, and maintaining the safety of the patients. Modelling Optimization and Control of Biomedical Systems covers: mathematical modelling of drug delivery systems; model analysis, parameter estimation, and approximation; optimization and control; sensitivity analysis & model reduction; multi-parametric programming and model predictive control; estimation techniques; physiologically-based patient model; control design for volatile anaesthesia; multiparametric model based approach to intravenous anaesthesia; hybrid model predictive control strategies; Type I Diabetes Mellitus; in vitro and in silico block of the integrated platform for the study of leukaemia; chemotherapy treatment as a process systems application; and more. Introduces readers to the Modelling, Control and Optimization of Biomedical Systems (MOBILE) project Presents in detail the theoretical background, computational tools, and methods that are used in all the different biomedical systems Teaches the theory for multi-parametric mixed-integer programming and explicit optimal control of volatile anaesthesia Provides an overview of the framework for modelling, optimization, and control of biomedical systems This book will appeal to students, researchers, and scientists working on the modelling, control, and optimization of biomedical systems and to those involved in cancer treatment, anaesthsia, and drug delivery systems.
Author: Giampiero Fusco
Publisher: Jessica Kingsley Publishers
ISBN: 1909141690
Category : Health & Fitness
Languages : en
Pages : 473
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Book Description
Far from being simply a sequence of techniques, as practised in many countries osteopathy is an independent primary health care system based on principles applied through a manual practice: a unique profession that takes care of the whole person through the application of five models (biomechanical, neurological, respiratory-circulatory, metabolic, and behavioral). These conceptual models of the relationship between structure and function allow osteopaths to evaluate treatment with the aim of promoting health rather than curing disease. This book is intended as a manual for both students and osteopathic professionals interested in exploring the principles, objectives, origins and application of the five osteopathic models, from traditional concepts up to a modern vision, based on evidence and critical thinking. The selection criteria and rules for the application of each model, with their limitations and potential, are examined, to enable the reader to understand the rationale behind their use in a comprehensive, holistic and patient-centered practice.
Author: Cheuk-Man Yu
Publisher: John Wiley & Sons
ISBN: 1444300253
Category : Medical
Languages : en
Pages : 464
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Book Description
Cardiac Resynchronization Therapy continues to evolve at a rapidpace. Growing clinical experience and additional clinical trialsare resulting in changes in how patients are selected for CRT. This new edition of the successful Cardiac ResynchronizationTherapy builds on the strengths of the first edition, providingbasic knowledge as well as an up-to-date summary of new advances inCRT for heart failure. Fully updated to include information ontechnological advances, trouble shooting and recent key clinicaltrials, and with nine new chapters, this expanded text provides thelatest information, keeping the reader up-to-date with this rapidlyevolving field. The second edition of Cardiac Resynchronization Therapyis an essential addition to your collection.
Author: Daniele Boffi
Publisher: Springer
ISBN: 3319966499
Category : Mathematics
Languages : en
Pages : 243
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Book Description
The book comprises contributions by some of the most respected scientists in the field of mathematical modeling and numerical simulation of the human cardiocirculatory system. It covers a wide range of topics, from the assimilation of clinical data to the development of mathematical and computational models, including with parameters, as well as their efficient numerical solution, and both in-vivo and in-vitro validation. It also considers applications of relevant clinical interest. This book is intended for graduate students and researchers in the field of bioengineering, applied mathematics, computer, computational and data science, and medicine wishing to become involved in the highly fascinating task of modeling the cardiovascular system.
Author: Nicholas Ayache
Publisher: Springer
ISBN: 3642019323
Category : Computers
Languages : en
Pages : 537
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Book Description
This book constitutes the refereed proceedings of the 5th International Conference on Functional Imaging and Modeling of the Heart, FIMH 2009, held in Nice, France in June 2009. The 54 revised full papers presented were carefully reviewed and selected from numerous submissions. The contributions cover topics such as cardiac imaging and electrophysiology, cardiac architecture imaging and analysis, cardiac imaging, cardiac electrophysiology, cardiac motion estimation, cardiac mechanics, cardiac image analysis, cardiac biophysical simulation, cardiac research platforms, and cardiac anatomical and functional imaging.
Author: Tommaso Mansi
Publisher: Academic Press
ISBN: 012817594X
Category : Science
Languages : en
Pages : 274
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Book Description
Artificial Intelligence for Computational Modeling of the Heart presents recent research developments towards streamlined and automatic estimation of the digital twin of a patient's heart by combining computational modeling of heart physiology and artificial intelligence. The book first introduces the major aspects of multi-scale modeling of the heart, along with the compromises needed to achieve subject-specific simulations. Reader will then learn how AI technologies can unlock robust estimations of cardiac anatomy, obtain meta-models for real-time biophysical computations, and estimate model parameters from routine clinical data. Concepts are all illustrated through concrete clinical applications. Presents recent advances in computational modeling of heart function and artificial intelligence technologies for subject-specific applications Discusses AI-based technologies for robust anatomical modeling from medical images, data-driven reduction of multi-scale cardiac models, and estimations of physiological parameters from clinical data Illustrates the technology through concrete clinical applications and discusses potential impacts and next steps needed for clinical translation
Author: Alexandru Morega
Publisher: Academic Press
ISBN: 0128178981
Category : Science
Languages : en
Pages : 321
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Book Description
Mathematical and numerical modelling of engineering problems in medicine is aimed at unveiling and understanding multidisciplinary interactions and processes and providing insights useful to clinical care and technology advances for better medical equipment and systems. When modelling medical problems, the engineer is confronted with multidisciplinary problems of electromagnetism, heat and mass transfer, and structural mechanics with, possibly, different time and space scales, which may raise concerns in formulating consistent, solvable mathematical models. Computational Medical Engineering presents a number of engineering for medicine problems that may be encountered in medical physics, procedures, diagnosis and monitoring techniques, including electrical activity of the heart, hemodynamic activity monitoring, magnetic drug targeting, bioheat models and thermography, RF and microwave hyperthermia, ablation, EMF dosimetry, and bioimpedance methods. The authors discuss the core approach methodology to pose and solve different problems of medical engineering, including essentials of mathematical modelling (e.g., criteria for well-posed problems); physics scaling (homogenization techniques); Constructal Law criteria in morphing shape and structure of systems with internal flows; computational domain construction (CAD and, or reconstruction techniques based on medical images); numerical modelling issues, and validation techniques used to ascertain numerical simulation results. In addition, new ideas and venues to investigate and understand finer scale models and merge them into continuous media medical physics are provided as case studies. Presents the fundamentals of mathematical and numerical modeling of engineering problems in medicine Discusses many of the most common modelling scenarios for Biomedical Engineering, including, electrical activity of the heart hemodynamic activity monitoring, magnetic drug targeting, bioheat models and thermography, RF and microwave hyperthermia, ablation, EMF dosimetry, and bioimpedance methods Includes discussion of the core approach methodology to pose and solve different problems of medical engineering, including essentials of mathematical modelling, physics scaling, Constructal Law criteria in morphing shape and structure of systems with internal flows, computational domain construction, numerical modelling issues, and validation techniques used to ascertain numerical simulation results
