Cancer Management in Man: Chemotherapy, Biological Therapy, Hyperthermia and Supporting Measures PDF Download
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Author: Boris Minev
Publisher: Springer Science & Business Media
ISBN: 904819704X
Category : Medical
Languages : en
Pages : 521
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Book Description
This book represents a comprehensive description and evaluation of the most up-to-date approaches to cancer management. Each chapter, prepared by leading basic researchers and clinicians, provides an in depth description of a specific method for cancer management. The chemotherapy section of the book is updated to include the newest drugs as well as those currently in development. Organized by drug class, this section provides the latest information on most drugs, including their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. The biological therapy section of the book provides expanded coverage of the currently used cytokines, vaccines, and cell based therapies of cancer. Full consideration is also given to other modern treatment approaches, such as tyrosine kinase inhibitors, inhibitors of tumor angiogenesis, and the transcatheter management of cancer. Current advances in hyperthermia in cancer treatment, hematologic and nutritional support, bone marrow transplantation, pain management and care of the terminally ill patients with cancer are also presented. In summary, this book provides a comprehensive coverage of the current knowledge on the most innovative, systematic and multidisciplinary approaches to the treatment of patients with cancer.
Author: Boris Minev
Publisher: Springer Science & Business Media
ISBN: 904819704X
Category : Medical
Languages : en
Pages : 521
Get Book Here
Book Description
This book represents a comprehensive description and evaluation of the most up-to-date approaches to cancer management. Each chapter, prepared by leading basic researchers and clinicians, provides an in depth description of a specific method for cancer management. The chemotherapy section of the book is updated to include the newest drugs as well as those currently in development. Organized by drug class, this section provides the latest information on most drugs, including their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. The biological therapy section of the book provides expanded coverage of the currently used cytokines, vaccines, and cell based therapies of cancer. Full consideration is also given to other modern treatment approaches, such as tyrosine kinase inhibitors, inhibitors of tumor angiogenesis, and the transcatheter management of cancer. Current advances in hyperthermia in cancer treatment, hematologic and nutritional support, bone marrow transplantation, pain management and care of the terminally ill patients with cancer are also presented. In summary, this book provides a comprehensive coverage of the current knowledge on the most innovative, systematic and multidisciplinary approaches to the treatment of patients with cancer.
Author: Alfred L. Goldson
Publisher: Springer Science & Business Media
ISBN: 9400925360
Category : Medical
Languages : en
Pages : 306
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Book Description
Previous volumes in this series have discussed the current progression have identified a variety of targets and strategies state of our knowledge concerning the pathophysiology of to allow these goals to be realized. This volume critically cancer growth and progression. The complexity of the in reviews approaches towards cancer management in man at teraction of malignant neoplasms and the host, the the levels of: detection, diagnosis, surgery, radiology, heterogeneity of malignant cell subpopulations, and the chronobiology and endocrine treatment. existence of metastatic tumor cells resistant to drug thera Several chapters review selected methods of cancer diag pies remain as significant clinical challenges to clinical on nosis. In addition, a variety of on-going and novel ap cologists. Indeed, conventional treatment regimens of che proaches for cancer treatment are also presented in this volume. Progress in the early detection of malignant neo motherapy, surgery and radiology are often ineffective for the therapy of a large variety of established metastatic can plasms, coupled with novel approaches for the therapy of cer in patients. When one considers the insidiousness of such neoplasms, may ultimately yield safe and well-tolerated agents for the selective therapy of solid malignancies. New progressive neoplastic growth and the emergence of con tinuously more aggressive and malignant cellular subpop therapeutic approaches, directed towards the biochemical ulations one is overwhelmed with the challenges inherent in and molecular targets identified in the earlier volumes of this series, may ultimately lead to the generation of new mo attempting to control malignant neoplasms.
Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 102
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Book Description
Author: Arthur S. Levine
Publisher: Springer Science & Business Media
ISBN: 9400925328
Category : Medical
Languages : en
Pages : 245
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Book Description
This volume reviews our current knowledge concerning can Several chapters discuss the contributions of genetic asp cer growth and progression as it relates to the etiology of ects, metabolism, endocrine-related aspects and nutrition to human cancer. As emphasized in Volumes I-V of this series, cancer progression. Moreover, our current knowledge con neoplastic diseases are multistep maladies. There are many cerning urbanization factors, radiation, therapy-induced causes for the appearance of neoplastic diseases. Earlier neoplasms, environmentally induced neoplasms (e. g. , chapters in the series have reviewed molecular and cellular mesotheliomas induced by asbestos) and malignant neo aspects of tumor initiation, promotion and progression to plasms in organ transplant recipients are summarized. the invasive and metastatic phenotype. Contributions to the The impact of AIDS on neoplasm development is re initiation and progression of neoplastic diseases are made by viewed from an epidemiologic perspective that explores mul natural features of the environment and by its contaminants tiple facets of immunity, infectious disease, sexual behavior and by nutritional factors. Neoplastic diseases show a dis and blood transfusion. Other chapters investigate the in tinct relationship to a variety of environmental stimuli and fluence of the host immune response in oncogenesis and the to diseases of a non-neoplastic nature. For example, familial relationship between atherosclerotic plaques and tumors.
Author: Elizier L. Gorelik
Publisher: Springer Science & Business Media
ISBN: 9400925344
Category : Medical
Languages : en
Pages : 318
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Book Description
This volume emphasizes metastasis/dissemination as im nective tissues, muscle, tumours of neuronal origins and portant processes in cancer growth and progression. teratomas. Previous volumes in this series have emphasized aspects of The broad array of neoplastic diseases, multiple target cancer progression, tumor invasion and tumor metastasis sites, and patterns of metastasis and dissemination underlie and the importance of these processes to the pathophysiol the importance of achieving crucial insights into particular ogy and morbidity of malignant disease. This volume builds neoplasms. An understanding of metastasis and dissemina on these earlier themes and emphasizes metastasis/disse tion in man remains an essential objective for the design of mination in man. Following a review of general patterns of new diagnostic and therapeutic strategies for the therapy of metastatic spread in man, metastasis to, or progression of established metastatic disease and spread accompanying neoplasms in several organ systems are highlighted, includ site-specific tumor progression. ing: the central nervous system, esophageal cancer, the lung, the large intestine, the liver, bone, epithelial neoplasms, Series Editor Volume Editor endocrine cells, pigmented tissues, supporting tissues, con- Hans E. Kaiser Elizier L. Gorelik VII ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.
Author: Elizabeth K. Weisburger
Publisher: Springer Science & Business Media
ISBN: 9400925263
Category : Medical
Languages : en
Pages : 210
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Book Description
but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.
Author: Ronald B. Herberman
Publisher: Springer Science & Business Media
ISBN: 9400925301
Category : Medical
Languages : en
Pages : 202
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Book Description
It is widely recognized that the host response to tumor munotherapy of experimental metastases in animal systems progression is an important determinant in cancer growth which are beginning to be developed for ultimate clinical and progression. Indeed, as indicated in Volume I of this trials of human cancer metastasis. series, the process of cancer growth and progression, leading This volume explores a variety of host properties that to tumor invasion and metastasis, is dependent upon the influence tumor development including dormancy, regress complex, dynamic interactions between the properties of the ion, and recurrence. In addition, current knowledge of the tumor as well as the properties of the host. While Volume III response of the central nervous system to cancer, cardiac of this series reviews in great detail the influence of tumor and pulmonary complications, dermatologic effects and development on the host, this volume emphasizes the in hematologic complications of malignancies is presented. fluence of the host on tumor development. These host re The endocrine and metabolic function of cancer patients, as sponses include host anti-tumor immune reactivity, tumor well as the production of hormones by tumors is also review dormancy, cachexia, multiple endocrine and paraneoplastic ed.
Author: L.A. Liotta
Publisher: Springer Science & Business Media
ISBN: 940092528X
Category : Medical
Languages : en
Pages : 250
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Book Description
Recent experimental evidence has made it increasingly clear In particular, this volume reviews the discrete steps involved that the properties of invasive, malignant cells during tumor in metastatic invasion: the interaction of invasive tumor cells development substantially impact on the host. This is under with extracellular matrices, the basement membrane, attach scored by a variety of biochemical properties of tumor cells ment to extracellular matrices, local proteolytic degradation during their differentiation and metastatic dissemination. of matrices, and the locomotion of invasive tumor cells These properties can be analyzed at different stages of tumor through such areas of localized degradation. The critical growth and progression and this volume explores the role of the cell surface in secondary tumor formation is characteristics of primary tumors as well as the shared reviewed as are important advances in the molecular biology characteristics of both primary and secondary tumors. of metastasis initiation and maintenance. Recent advances The primary tumor comes into existence following in the role of DNA methylation in the generation of tumor preneoplastic biochemical and cellular events that ultimate cell heterogeneity and tumor progression are also critically ly result in malignant transformation. Various aspects of summarized. Chapters in this volume also review molecular metabolism, predetermined by nutritional status, often play aspects of metastatic progression, and the use of the tech a basic role. Obesity, for example, is cancer-promoting. Cell nologies of DNA transfection and somatic cell fusion in the surface carbohydrates, cytoskeletal proteins, glycoproteins, exploration of molecular aspects of metastatic progression.
Author: Hans E. Kaiser
Publisher: Springer Science & Business Media
ISBN: 9400910916
Category : Medical
Languages : en
Pages : 270
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Book Description
Of the interaction and relationship of both systems is chal In this volume, aspects of neoplastic spread, already elu cidated in Volumes I-IV of this series, are considered lenging indeed. against a broad biological background. The mammalian The volume also reviews environmental oncology and species-specific aspects of environmental chain reactions. It orders constituting the logical framework for man as focal point of a comparative oncology are reviewed. Selected is apparent that the environment plays a significant role in examples of neoplastic progression in various taxonomic the development of neoplasms. Neoplasms among the spe units are provided, beginning with the opposite pole of ci es have become much more common as a result of man's taxonomic development, the vascular plants, where no impact on the environment. The latter chapters present a metastatis of malignant neoplasms occur. Among in brief review of geologic and technologic and cuItural vertebrates, vertebrates, and vascular plants, Iining mem changes, and the implications of species-specific cancer pro branes (epithelia) exhibit the highest degree of comparabil gression. The remainder of this section outlines a number of ity. Metastases also occur, but more rarely, in invertebrates; selected chain reactions leading to neoplastic development and are discussed as they are found in the nonmammalian in certain members of these chains. A discussion of the vertebrates: in fish, amphibians, reptiles, and birds. Diseases storage of chemical carcinogens in plants and their interac ofthe leukemia (Ieucosis)-Iymphoma complex are present in tion with other causes of neoplastic growth is also included.
Author: Charlette Gallagher-Allred
Publisher: Routledge
ISBN: 1317826906
Category : Health & Fitness
Languages : en
Pages : 164
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Book Description
This scholarly book enables health care professionals to appropriately address hospice patients’and families’concerns about nutrition and hydration. Nutrition and Hydration in Hospice Care is a comprehensive resource that provides hands-on practical information that readers can use in everyday hospice practice. The chapters identify problems, solutions, and ethical issues of nutrition and hydration in hospice care.The contributing authors provide the way for health care professionals, especially those in nursing, dietary, and pharmacy units, to jointly and effectively manage troublesome symptoms and ethical issues. The following topics are included in the scope of coverage: nutrition/hydration needs during end-stage disease nursing and dietary roles in identifying nutrition/hydration problems and implementing treatment how needs of dying children and adults are different legal and ethical dilemmas of withholding or withdrawing nutrition and hydration appropriate and inappropriate uses of enteral and parenteral nutrition support during end-stage diseases food service considerations in inpatient hospice facilities appetite stimulant use in palliative careBecause Nutrition and Hydration in Hospice Care is comprehensive, all members of hospice staffs can find practical information to use each day. The authors cover issues not found in other books for nurses, dietitians, pharmacists, and physicians. They will find the information ready to apply at their work settings.
