On the Cancer Frontier PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download On the Cancer Frontier PDF full book. Access full book title On the Cancer Frontier by Paul Marks. Download full books in PDF and EPUB format.
Author: Paul Marks
Publisher: PublicAffairs
ISBN: 1610392531
Category : Medical
Languages : en
Pages : 274
Get Book Here
Book Description
In 1950, a diagnosis of cancer was all but a death sentence. Mortality rates only got worse, and as late as 1986, an article in the New England Journal of Medicine lamented: "We are losing the war against cancer." Cancer is one of humankind's oldest and most persistent enemies; it has been called the existential disease. But we are now entering a new, and more positive, phase in this long campaign. While cancer has not been cured -- and a cure may elude us for a long time yet -- there has been a revolution in our understanding of its nature. Years of brilliant science have revealed how this individualistic disease seizes control of the foundations of life -- our genes -- and produces guerrilla cells that can attack and elude treatments. Armed with those insights, scientists have been developing more effective weapons and producing better outcomes for patients. Paul A. Marks, MD, has been a leader in these efforts to finally control this devastating disease. Marks helped establish the strategy for the "war on cancer" in 1971 as a researcher and member of President Nixon's cancer panel. As the president and chief executive officer for nineteen years at the world's pre-eminent cancer hospital, the Memorial Sloan-Kettering Cancer Center, he was instrumental in ending the years of futility. He also developed better therapies that promise a new era of cancer containment. Some cancers, like childhood leukemia and non-Hodgkin's lymphoma, that were once deadly conditions, are now survivable -- even curable. New steps in prevention and early diagnosis are giving patients even more hope. On the Cancer Frontier is Marks' account of the transformation in our understanding of cancer and why there is growing optimism in our ability to stop it.
Author: Paul Marks
Publisher: PublicAffairs
ISBN: 1610392531
Category : Medical
Languages : en
Pages : 274
Get Book Here
Book Description
In 1950, a diagnosis of cancer was all but a death sentence. Mortality rates only got worse, and as late as 1986, an article in the New England Journal of Medicine lamented: "We are losing the war against cancer." Cancer is one of humankind's oldest and most persistent enemies; it has been called the existential disease. But we are now entering a new, and more positive, phase in this long campaign. While cancer has not been cured -- and a cure may elude us for a long time yet -- there has been a revolution in our understanding of its nature. Years of brilliant science have revealed how this individualistic disease seizes control of the foundations of life -- our genes -- and produces guerrilla cells that can attack and elude treatments. Armed with those insights, scientists have been developing more effective weapons and producing better outcomes for patients. Paul A. Marks, MD, has been a leader in these efforts to finally control this devastating disease. Marks helped establish the strategy for the "war on cancer" in 1971 as a researcher and member of President Nixon's cancer panel. As the president and chief executive officer for nineteen years at the world's pre-eminent cancer hospital, the Memorial Sloan-Kettering Cancer Center, he was instrumental in ending the years of futility. He also developed better therapies that promise a new era of cancer containment. Some cancers, like childhood leukemia and non-Hodgkin's lymphoma, that were once deadly conditions, are now survivable -- even curable. New steps in prevention and early diagnosis are giving patients even more hope. On the Cancer Frontier is Marks' account of the transformation in our understanding of cancer and why there is growing optimism in our ability to stop it.
Author: Eric P. Cohen
Publisher: Oxford University Press, USA
ISBN: 0199580197
Category : Medical
Languages : en
Pages : 382
Get Book Here
Book Description
Cancer and the Kidney covers the challenging overlap area of nephrology and oncology, both in terms of kidney problems in cancer patients, and cancer that affects kidney patients, including assessment of kidney function, to paraneoplastic disorders, acquired cysts and native kidney cancers, and all points inbetween.
Author: Giuseppe Giaccone
Publisher: Frontiers Media SA
ISBN: 288945939X
Category :
Languages : en
Pages : 213
Get Book Here
Book Description
Foreword from the Field Chief Editor, Giuseppe Giaccone Once again Frontiers in Oncology has started the year on a positive note, breaking previous records for submissions and publications, as well as the number of Research Topic article collections posted. The journal continues to grow in size, adding an 18th section focusing on Cancer Metabolism, led by Michael Lisanti and Ubaldo Martinez-Outschoorn, and has brought on a total of five new Chief Editors. Here, introducing Frontiers in Oncology: Quarterly Highlights, we feature a collection of carefully selected articles published during the first quarter of 2019 across the different sections. With a record number of papers to choose from, the papers enclosed in this Special Edition highlight some of the recent advances across the different disciplines. With an array of papers looking at everything from translational research to association studies and clinical trial results, Frontiers in Oncology continues to publish high-quality research from researchers around the world. Many of the recently posted Research Topics in the journal focus on early diagnosis and prevention, as well as the importance of survivorship studies and outcomes of cancer treatment. Consideration of such aspects of cancer research and treatment is pivotal in the global effort towards increased survival rates and improved quality of life. With ASCO 2019 marking the end of Q1 and the transition into Q2, the journal looks forward to the rest of the year, and continuing to play an active role in the research community. Giuseppe Giaccone
Author: 桑野信彦
Publisher:
ISBN: 9784753220052
Category : Literary Collections
Languages : ja
Pages : 0
Get Book Here
Book Description
Author: Paul Marks
Publisher: Public Affairs
ISBN: 1610392523
Category : Medical
Languages : en
Pages : 274
Get Book Here
Book Description
Describes how and what doctors have learned about cancer and the mechanisms of the rogue, abnormal cells since the 1950s and catalogs the advances and strides made in treating and fighting the disease in the last half-century.
Author: Giuseppe Giaccone
Publisher: Frontiers Media SA
ISBN: 2889457818
Category :
Languages : en
Pages : 233
Get Book Here
Book Description
Advances in cancer research over the recent decades have been plentiful and often successful, with 5 year survival rates increasing almost uniformly across the board. The advent of new technologies has presented solutions for yesterday’s barriers to research, allowing us to leap forward in our ability to prevent, diagnose, and treat various cancers. Developments in omics studies has provided new insights into the underlying molecular basis of different cancers and their subtypes, greatly enhancing our understanding of the vast heterogeneity that exists. Progress in our ability to diagnose and detect early-stage cancers has resulted in numerous screening and prevention programs. Novel imaging technologies allow us to study and comprehend cancers with greater clarity than ever before. Although the field, as a whole, has experienced many successes, arduous challenges must be overcome in order to see continued success. The truth of the matter is cancer related deaths continue to rise in number worldwide, especially in lower- and middle-income countries. It is evident that there is still a lot of work to be done. This Frontiers in Oncology Special Issue marks the 1st edition of a collection of selected articles published in the journal over the course of the previous calendar year, highlighting ongoing research and advances being carried out in the different disciplines of cancer research.
Author: Carsten Nieder
Publisher: Springer
ISBN: 3319418254
Category : Medical
Languages : en
Pages : 368
Get Book Here
Book Description
This book, now in its second edition, provides a comprehensive overview of current re-irradiation strategies, with detailed discussion of re-irradiation methods, technical aspects, the role of combined therapy with anticancer drugs and hyperthermia, and normal tissue tolerance. In addition, disease specific chapters document recent clinical results and future research directions. All chapters from the first edition have been revised and updated to take account of the latest developments and research findings, including those from prospective studies. Due attention is paid to the exciting developments in the fields of proton irradiation and frameless image-guided ablative radiotherapy. The book documents fully how refined combined modality approaches and significant technical advances in radiation treatment planning and delivery have facilitated the re-irradiation of previously exposed volumes, allowing both palliative and curative approaches to be pursued at various disease sites. Professionals involved in radiation treatment planning and multimodal oncology treatment will find it to be an invaluable aid in understanding the benefits and limitations of re-irradiation and in designing prospective trials.
Author: Kieth S Miller
Publisher: Independently Published
ISBN:
Category : Health & Fitness
Languages : en
Pages : 0
Get Book Here
Book Description
The Dual Frontiers of Cancer: Bridging the Gap Between Research and Treatment - Interplay of Signaling and the Tumor Microenvironment Immerse yourself in the revolutionary world of cancer research with "The Dual Frontiers of Cancer." This essential book explores the dynamic relationship between cancer signaling pathways and the tumor microenvironment, shedding light on the latest advancements in cancer treatment. - In-Depth Understanding: Uncover the molecular mechanisms behind cancer signaling and how researchers are developing innovative ways to target these pathways. - Microenvironment Dynamics: Learn about the critical role of the tumor microenvironment and how it influences cancer development and progression. - From Research to Treatment: See how groundbreaking discoveries are leading to new, more effective treatments that offer hope for patients worldwide. - Future Innovations: Get a glimpse into the future of cancer research, where emerging technologies and strategies promise to change the way we fight this disease. Whether you're a medical professional, researcher, student, or someone who wants to get informed about cancer, this book provides a comprehensive and accessible guide to the latest advancements in cancer biology. With engaging narratives and insightful analysis, "The Dual Frontiers of Cancer" bridges the gap between complex scientific concepts and practical treatment applications, making it a must-read for anyone interested in the future of cancer care.
Author: Tejinder Kataria
Publisher: BoD – Books on Demand
ISBN: 9535111639
Category : Science
Languages : en
Pages : 230
Get Book Here
Book Description
The mode of action by radiation is postulated to be the production of double strand breaks of DNA. The repair of double strand breaks occurs through non homologous end joining through acetylation of histone proteins by histone acetyltransferases (HATs). The fixation of double strand breaks through HAT inhibitors is a promising application for radiation sensitization in the clinic. P53 is a tumour suppressor gene and its mutation has been implicated in 60% of human cancers. As one of the pivotal anticancer genes, P53 controls the transcription and translation of a series of genes. The kinetics of DNA double strand break generation and their co relation to P53 status, ATM and ARF activation are computed and modelled for understanding the potential of such research.
Author: Karol Sikora
Publisher:
ISBN: 9780954579401
Category :
Languages : en
Pages : 96
Get Book Here
Book Description
