Callosal Agenesis

Callosal Agenesis PDF Author: Maryse Lassone
Publisher: Springer Science & Business Media
ISBN: 1461304873
Category : Medical
Languages : en
Pages : 304

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Book Description
This book is devoted to the description of agenesis of the corpus callosum, a congenital malformation of midline structures in the brain that may be regarded as a natural model of the "split-brain. " First reported by Rei! in 1812, this anomaly has since been described by several investigators. Interest in this malformation was revived in the 1970s by studies of interhemispheric transfer in Bogen and Vogel's commissurotomized patients and the subsequent findings by Sperry that acallosal patients were devoid of the typical disconnection deficits found in patients with surgical transection of the corpus callosum. Since this seminal work, the bulk of neuropsychological research on callosal agenesis has focused on the particulars of interhemispheric transfer and integration. An ever-growing literature has emerged on the subject, attempting to specify the extent and limits of neural plasticity in a nervous system that has evolved in the absence of the most important interhemispheric pathway. Whilst callosal agenesis proves to be an excellent model of cerebral plasticity, it has to be pointed out that this anomaly is often associated with other malformations and neurological diseases that may result in different degrees of mental retardation or other cognitive and sensorimotor deficits. In this context, neurological research on callosal agenesis has concentrated on the description of various syndromes associated with this pathology as well as on the attempt to specify its neurobehavioral manifestations.

Callosal Agenesis

Callosal Agenesis PDF Author: Maryse Lassone
Publisher: Springer Science & Business Media
ISBN: 1461304873
Category : Medical
Languages : en
Pages : 304

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Book Description
This book is devoted to the description of agenesis of the corpus callosum, a congenital malformation of midline structures in the brain that may be regarded as a natural model of the "split-brain. " First reported by Rei! in 1812, this anomaly has since been described by several investigators. Interest in this malformation was revived in the 1970s by studies of interhemispheric transfer in Bogen and Vogel's commissurotomized patients and the subsequent findings by Sperry that acallosal patients were devoid of the typical disconnection deficits found in patients with surgical transection of the corpus callosum. Since this seminal work, the bulk of neuropsychological research on callosal agenesis has focused on the particulars of interhemispheric transfer and integration. An ever-growing literature has emerged on the subject, attempting to specify the extent and limits of neural plasticity in a nervous system that has evolved in the absence of the most important interhemispheric pathway. Whilst callosal agenesis proves to be an excellent model of cerebral plasticity, it has to be pointed out that this anomaly is often associated with other malformations and neurological diseases that may result in different degrees of mental retardation or other cognitive and sensorimotor deficits. In this context, neurological research on callosal agenesis has concentrated on the description of various syndromes associated with this pathology as well as on the attempt to specify its neurobehavioral manifestations.

Agenesis of the Corpus Callosum

Agenesis of the Corpus Callosum PDF Author: Dianne M. Porter
Publisher: iUniverse
ISBN: 1450249892
Category : Biography & Autobiography
Languages : en
Pages : 62

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Book Description
This book contains information about Agenesis of the Corpus Callosum and various medical terminology that goes along with this condition. It is a beneficial tool for those who have this disease or for anyone who wants to learn about it.

Callosal Agenesis

Callosal Agenesis PDF Author: Maryse Lassone
Publisher:
ISBN: 9781461304883
Category :
Languages : en
Pages : 324

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Book Description


Aicardi Syndrome a.k.a. Callosal Agenesis: Definition, Etiology, Molecular Pathogenesis, Prevalence and more.

Aicardi Syndrome a.k.a. Callosal Agenesis: Definition, Etiology, Molecular Pathogenesis, Prevalence and more. PDF Author: Dr. Hakim. K. Saboowala
Publisher: Dr.Hakim Saboowala
ISBN:
Category : Medical
Languages : en
Pages : 37

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Book Description
Aicardi Syndrome a.k.a. Callosal Agenesis: Definition, Etiology, Molecular Pathogenesis, Prevalence and more. In 1965, a French neurologist, Dr Jean Dennis Aicardi, described 8 children with infantile spasm-in-flexion, total or partial agenesis of the corpus callosum, and variable ocular abnormalities. This clinical scenario, already reported in 1949, was recognized as an entity distinct from congenital infections. An additional 7 patients were described in 1969, and in 1972, Dennis and Bower established the Aicardi syndrome designation. Further patient study demonstrated other less consistent characteristics outside the classic triad of findings. These additional characteristics include: · Abnormal facies, · Cleft lip and palate, · Vertebral body abnormalities, and · Abnormalities of neuronal migration. Most children have a moderate to severe degree of mental retardation, although less severely affected children occasionally are described. An attempt has been made in this Booklet to describe Etiology, Molecular Pathogenesis, Prevalence etc. comprehensively for enthusiastic Medicos along with relevant ILLUSTRATIONS for better understanding. …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)

Structure and Function of Cerebral Commissures

Structure and Function of Cerebral Commissures PDF Author: I. Steele Russell
Publisher:
ISBN: 9780333234105
Category : Anterior commissure
Languages : en
Pages : 502

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Book Description


Volpe's Neurology of the Newborn E-Book

Volpe's Neurology of the Newborn E-Book PDF Author: Joseph J. Volpe
Publisher: Elsevier Health Sciences
ISBN: 0443105456
Category : Medical
Languages : en
Pages : 1845

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Book Description
Stay up to date with today’s latest advances in diagnosis and management, as well as the many scientific and technological advances that are revolutionizing neonatal neurology, with the definitive text in the field. Volpe's Neurology of the Newborn, 7th Edition, shares the knowledge and expertise of world authority Dr. Joseph Volpe, who, along with Dr. Terrie E. Inder of Children’s Hospital of Orange County and other distinguished editors, brings a wealth of insight to this classic text. Known for its clear, engaging writing style, vibrant, full-color illustrations, and authoritative information throughout, this reference is an indispensable resource for those who provide care for neonates with neurological conditions. Provides clear, comprehensive coverage of neonatal neurology in Dr. Joseph Volpe’s own legendary, readable manner—for a masterful, cohesive source of answers to any question that arises in your practice. Brings the latest science into the clinical setting, with an emphasis on translating new knowledge to the infant’s bedside. Offers comprehensive updates with summary tables and text to reflect major advances in the study of hemorrhage; new insights into molecular genetics and molecular characterization of brain tumors; significant advances in drugs and the developing nervous system; and much more. Includes new chapters on fetal neurology which address the importance of understanding and investigating the maternal-fetal origins of neonatal disease, as well as new chapters on neurodevelopmental follow-up, inflammation, and neurology in low-resource settings. Contains more than 1,000 illustrations: clinical and pathological specimens, key experimental findings, schematics, algorithms, anatomical drawings, and neuroimaging throughout, as well as numerous tables and boxes that synthesize key points. Any additional digital ancillary content may publish up to 6 weeks following the publication date.

Creating Connections in the Developing Brain

Creating Connections in the Developing Brain PDF Author: Ilan Gobius
Publisher: Morgan & Claypool Publishers
ISBN: 1615040781
Category : Medical
Languages : en
Pages : 51

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Book Description
The corpus callosum is the largest fibre tract in the human brain and subserves many of the brain's higher-order functions. Disconnection syndromes resulting from surgical ablation, developmental absence (agenesis of the corpus callosum), disease, or injury of the corpus callosum can have profound consequences on cognition. Callosal development involves an intricate series of sequential and concurrent processes, including telencephalic induction, midline tissue patterning, production and specification of callosal neurons. In addition, axon extension and long-range axonal guidance from one hemisphere to the other are required for functional circuit formation in the contralateral hemisphere. Genetic or traumatic disruption to any part of this sequence is pathogenic. Understanding the key processes involved in callosal development is the first step in providing both better neuropsychological outcomes and improved diagnostic and prognostic tools for congenital disconnection syndromes in the future.

Atlas of Clinical Neurology E-Book

Atlas of Clinical Neurology E-Book PDF Author: G. David Perkin
Publisher: Elsevier Health Sciences
ISBN: 1437737811
Category : Medical
Languages : en
Pages : 467

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Book Description
Atlas of Clinical Neurology, by David Perkin, Douglas C. Miller, Russell Lane, Maneesh C. Patel, and Fred H. Hochberg, delivers the most powerful, clinically oriented image collection of any reference in your specialty - to help you accurately diagnose any condition you see in practice! Approximately 2,000 large, high-quality images – 1,000 in full color - capture the characteristic physical examination and imaging findings of every type of neurological disorder. All of the diagnostic imaging studies have been updated to reflect the dramatic advances in neuroimaging. Updates throughout include a brand-new chapter on myopathies and myasthenia, expanded coverage of epilepsy, and an entire chapter devoted to extrapyramidal disorders. The result is the ultimate diagnostic resource in neurology! Find a perfect match for your clinical findings with the aid of the most powerful, clinically oriented image collection found in any neurology atlas: 2,000 illustrations, 1,000 in full color! Interpret the findings from the latest neuroimaging techniques with the aid of thoroughly updated images representing the most recent advances. Effectively overcome difficult diagnostic challenges with a brand-new chapter on myopathies and myasthenia, expanded coverage of epilepsy, and an entire chapter devoted to extrapyramidal disorders.

Paediatric Neurology

Paediatric Neurology PDF Author: Ingrid Gamstorp
Publisher: Butterworth-Heinemann
ISBN:
Category : Medical
Languages : en
Pages : 438

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Book Description
Paediatric Neurology, Second Edition presents management guidelines of neurological disorders in infants and children. This book is composed of 21 chapters that discuss the clinical examination, laboratory studies, and diagnosis of the injury, as well as the neurological analysis of a child. The opening chapters describe some of the examinations of infant and children, including the use of electroencephalography, electromyography, and measurement of the conduction velocity of peripheral nerves, examination of the spinal fluid, imaging techniques applicable to the neuromuscular system. A chapte ...

Micro-, Meso- and Macro-Connectomics of the Brain

Micro-, Meso- and Macro-Connectomics of the Brain PDF Author: Henry Kennedy
Publisher: Springer
ISBN: 3319277774
Category : Medical
Languages : en
Pages : 173

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Book Description
This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.