Caged Compounds

Caged Compounds PDF Author: Gerard Marriott
Publisher: Academic Press
ISBN:
Category : Medical
Languages : en
Pages : 584

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Book Description
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 285 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences.

Caged Compounds

Caged Compounds PDF Author: Gerard Marriott
Publisher: Academic Press
ISBN:
Category : Medical
Languages : en
Pages : 584

Get Book Here

Book Description
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 285 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences.

Development of photoactivatable caged compounds for biological applications

Development of photoactivatable caged compounds for biological applications PDF Author: Dominga Rogolino
Publisher:
ISBN:
Category :
Languages : it
Pages : 133

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Book Description


Synthesis of Caged NADP Compounds for Use in the Time-resolved X-ray Crystallographic Study of Isocitrate Dehydrogenase

Synthesis of Caged NADP Compounds for Use in the Time-resolved X-ray Crystallographic Study of Isocitrate Dehydrogenase PDF Author: Bruce Elliot Cohen
Publisher:
ISBN:
Category :
Languages : en
Pages : 408

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Book Description


High Content Screening

High Content Screening PDF Author: D. Lansing Taylor
Publisher: Springer Science & Business Media
ISBN: 1597452173
Category : Science
Languages : en
Pages : 437

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Book Description
There has always been some tension between proponents of hypothesis-driven and discovery-driven research in the broad field of life sciences. Academic research has been primarily focused on hypothesis-driven research. However, the success of the human genome project, a discovery-driven research approach, has opened the door to adding other types of discovery-driven research to a continuum of research approaches. In contrast, drug discovery research in the pharmaceutical industry has embraced discovery-driven research for many years. A good example has been the discovery of active compounds from large chemical libraries, through screening campaigns. The success of the human genome project has also demonstrated the need for both academic researchers and industrial researchers to now understand the functions of genes and gene products. The cell is the basic unit of life and it has been at the cellular level where function can be demonstrated most cost-effectively and rapidly. High content screening (HCS) was developed by Cellomics Inc. in the mid-1990s to address the need for a platform that could be used in the discovery-driven research and development required to understand the functions of genes and gene products at the level of the cell.

The Encapsulation Phenomenon

The Encapsulation Phenomenon PDF Author: Yan Voloshin
Publisher: Springer
ISBN: 3319277383
Category : Science
Languages : en
Pages : 653

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Book Description
This fundamental book presents the most comprehensive summary of the current state of the art in the chemistry of cage compounds. It introduces different ways of how ions and molecules can be encapsulated by three-dimensional caging ligands to form molecular and polymeric species: covalent, supramolecular, and coordination capsules. The authors introduce their classification, reactivity, and selected practical applications. Because encapsulation can isolate caged ions and molecules from external factors, the encapsulated species can exhibit unique physical and chemical properties. The resulting specific reactivity and selectivity can open up a range of applications, including chemical separation, recognition, chiral separation, catalysis, applications as sensors or probes, as molecular or supramolecular devices, or molecular carriers (cargo).A particularly strong emphasis in this book is on the summary and review of the synthesis of various types of cage compounds. Readers will find over 850 literature references summarized and clearly represented in over 600 schemes and illustrations. The book is structured by the types of caging ligands (covalent, supramolecular, or coordination capsules). The authors further arranged the chapters by ligand classes and types of encapsulated species (neutral molecules, anions, or cations). Readers will hence find an exhaustive reference resource and summary of the current state of research into encapsulated species, nowadays almost a separated realm of modern chemistry.

Cellular Neurobiology

Cellular Neurobiology PDF Author: John Chad
Publisher: Oxford University Press
ISBN: 9780199631070
Category : Business & Economics
Languages : en
Pages : 316

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Book Description
Brings together a large number of techniques which are useful in exploring the functions of molecules, and the resolution of neurobiological processes at the cellular level.

Carbocyclic Cage Compounds

Carbocyclic Cage Compounds PDF Author: Eiji Ōsawa
Publisher: VCH Publishers
ISBN:
Category : Cage hydrocarbons
Languages : en
Pages : 432

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Book Description


Bioanalytics

Bioanalytics PDF Author: Friedrich Lottspeich
Publisher: John Wiley & Sons
ISBN: 3527694463
Category : Science
Languages : en
Pages : 1810

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Book Description
Analytical methods are the essential enabling tools of the modern biosciences. This book presents a comprehensive introduction into these analytical methods, including their physical and chemical backgrounds, as well as a discussion of the strengths and weakness of each method. It covers all major techniques for the determination and experimental analysis of biological macromolecules, including proteins, carbohydrates, lipids and nucleic acids. The presentation includes frequent cross-references in order to highlight the many connections between different techniques. The book provides a bird's eye view of the entire subject and enables the reader to select the most appropriate method for any given bioanalytical challenge. This makes the book a handy resource for students and researchers in setting up and evaluating experimental research. The depth of the analysis and the comprehensive nature of the coverage mean that there is also a great deal of new material, even for experienced experimentalists. The following techniques are covered in detail: - Purification and determination of proteins - Measuring enzymatic activity - Microcalorimetry - Immunoassays, affinity chromatography and other immunological methods - Cross-linking, cleavage, and chemical modification of proteins - Light microscopy, electron microscopy and atomic force microscopy - Chromatographic and electrophoretic techniques - Protein sequence and composition analysis - Mass spectrometry methods - Measuring protein-protein interactions - Biosensors - NMR and EPR of biomolecules - Electron microscopy and X-ray structure analysis - Carbohydrate and lipid analysis - Analysis of posttranslational modifications - Isolation and determination of nucleic acids - DNA hybridization techniques - Polymerase chain reaction techniques - Protein sequence and composition analysis - DNA sequence and epigenetic modification analysis - Analysis of protein-nucleic acid interactions - Analysis of sequence data - Proteomics, metabolomics, peptidomics and toponomics - Chemical biology

Chemical Studies of Caged Compounds

Chemical Studies of Caged Compounds PDF Author: Belagaje Ramamoorthy
Publisher:
ISBN:
Category :
Languages : en
Pages : 274

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Book Description


Nitric Oxide

Nitric Oxide PDF Author: Lester Packer
Publisher: Gulf Professional Publishing
ISBN: 9780121821692
Category : Antioxidants
Languages : en
Pages : 598

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Book Description