Burger's Medicinal Chemistry and Drug Discovery, Therapeutic Agents

Burger's Medicinal Chemistry and Drug Discovery, Therapeutic Agents PDF Author: Manfred E. Wolff
Publisher: Wiley-Interscience
ISBN: 9780471575580
Category : Science
Languages : en
Pages : 680

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Book Description
The latest advances in the world of medicinal chemistry and drug discovery from the foremost reference in the field . . . BURGER'S MEDICINAL CHEMISTRY AND DRUG DISCOVERY, FIFTH EDITION, Volume 3: Therapeutic Agents Renowned for its incisive, systematic examination of the newest classes of therapeutic drugs, Burger's Medicinal Chemistry and Drug Discovery has become the professional's premier tool for assessing their structure, behavior, and design. Volume 3 begins the discussion of two classes of medicines-CNS drugs and endocrine drugs-essential to treatment regimens for mental illness and mediator imbalances. A two-part format, arranged by drug class, catalogs the findings that reflect the breadth and importance of both research specialties: CNS drugs: Endocrine drugs: * General anesthetics * Male sex hormones and analogs * Antiparkinsonism drugs * Antiallergic agents * Sedatives and hypnotics * Retinoids * Anticonvulsants * Insulin analogs * Agents used in neurodegenerative disorders * Analgesics Burger's Medicinal Chemistry, Fifth Edition consists of five volumes: Volume 1: Principles and Practice (0-471-57556-9) 1995 ". . . an essential addition to the libraries of any medicinal chemist . . . an outstanding work . . . highly praised as a fountain of information in drug studies and research."-Journal of Medicinal Chemistry * Volume 2: Therapeutic Agents (0-471-57557-7) 1996 * Volume 3: Therapeutic Agents (0-471-57558-5) 1996 * Volume 4: Therapeutic Agents (0-471-57559-3) 1997 * Volume 5: Therapeutic Agents (0-471-57560-7) 1997

Burger's Medicinal Chemistry and Drug Discovery, Therapeutic Agents

Burger's Medicinal Chemistry and Drug Discovery, Therapeutic Agents PDF Author: Manfred E. Wolff
Publisher: Wiley-Interscience
ISBN: 9780471575580
Category : Science
Languages : en
Pages : 680

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Book Description
The latest advances in the world of medicinal chemistry and drug discovery from the foremost reference in the field . . . BURGER'S MEDICINAL CHEMISTRY AND DRUG DISCOVERY, FIFTH EDITION, Volume 3: Therapeutic Agents Renowned for its incisive, systematic examination of the newest classes of therapeutic drugs, Burger's Medicinal Chemistry and Drug Discovery has become the professional's premier tool for assessing their structure, behavior, and design. Volume 3 begins the discussion of two classes of medicines-CNS drugs and endocrine drugs-essential to treatment regimens for mental illness and mediator imbalances. A two-part format, arranged by drug class, catalogs the findings that reflect the breadth and importance of both research specialties: CNS drugs: Endocrine drugs: * General anesthetics * Male sex hormones and analogs * Antiparkinsonism drugs * Antiallergic agents * Sedatives and hypnotics * Retinoids * Anticonvulsants * Insulin analogs * Agents used in neurodegenerative disorders * Analgesics Burger's Medicinal Chemistry, Fifth Edition consists of five volumes: Volume 1: Principles and Practice (0-471-57556-9) 1995 ". . . an essential addition to the libraries of any medicinal chemist . . . an outstanding work . . . highly praised as a fountain of information in drug studies and research."-Journal of Medicinal Chemistry * Volume 2: Therapeutic Agents (0-471-57557-7) 1996 * Volume 3: Therapeutic Agents (0-471-57558-5) 1996 * Volume 4: Therapeutic Agents (0-471-57559-3) 1997 * Volume 5: Therapeutic Agents (0-471-57560-7) 1997

Burger's Medicinal Chemistry and Drug Discovery: Principles and practice

Burger's Medicinal Chemistry and Drug Discovery: Principles and practice PDF Author: Alfred Burger
Publisher:
ISBN:
Category : Pharmaceutical chemistry
Languages : en
Pages :

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Book Description


Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set

Burger's Medicinal Chemistry, Drug Discovery and Development, 8 Volume Set PDF Author:
Publisher: John Wiley & Sons
ISBN: 111953030X
Category : Science
Languages : en
Pages : 6057

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Book Description
Burger’s Medicinal Chemistry, Drug Discovery and Development Explore the freshly updated flagship reference for medicinal chemists and pharmaceutical professionals The newly revised eighth edition of the eight-volume Burger’s Medicinal Chemistry, Drug Discovery and Development is the latest installment in this celebrated series covering the entirety of the drug development and discovery process. With the addition of expert editors in each subject area, this eight-volume set adds 35 chapters to the extensive existing chapters. New additions include analyses of opioid addiction treatments, antibody and gene therapy for cancer, blood-brain barrier, HIV treatments, and industrial-academic collaboration structures. Along with the incorporation of practical material on drug hunting, the set features sections on drug discovery, drug development, cardiovascular diseases, metabolic diseases, immunology, cancer, anti-Infectives, and CNS disorders. The text continues the legacy of previous volumes in the series by providing recognized, renowned, authoritative, and comprehensive information in the area of drug discovery and development while adding cutting-edge new material on issues like the use of artificial intelligence in medicinal chemistry. Included: Volume 1: Methods in Drug Discovery, edited by Kent D. Stewart Volume 2: Discovering Lead Molecules, edited by Kent D. Stewart Volume 3: Drug Development, edited by Ramnarayan S. Randad and Michael Myers Volume 4: Cardiovascular, Endocrine, and Metabolic Diseases, edited by Scott D. Edmondson Volume 5: Pulmonary, Bone, Immunology, Vitamins, and Autocoid Therapeutic Agents, edited by Bryan H. Norman Volume 6: Cancer, edited by Barry Gold and Donna M. Huryn Volume 7: Anti-Infectives, edited by Roland E. Dolle Volume 8: CNS Disorders, edited by Richard A. Glennon Perfect for research departments in the pharmaceutical and biotechnology industries, Burger’s Medicinal Chemistry, Drug Discovery and Development can be used by graduate students seeking a one-stop reference for drug development and discovery and deserves its place in the libraries of biomedical research institutes, medical, pharmaceutical, and veterinary schools.

Burger's Medicinal Chemistry and Drug Discovery: Therapeutic agents

Burger's Medicinal Chemistry and Drug Discovery: Therapeutic agents PDF Author: Alfred Burger
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 680

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Book Description


Burger's Medicinal Chemistry and Drug Discovery, Drug Discovery

Burger's Medicinal Chemistry and Drug Discovery, Drug Discovery PDF Author: Donald J. Abraham
Publisher: Wiley-Interscience
ISBN: 9780471270904
Category : Science
Languages : en
Pages : 972

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Book Description
This is Volume 1: Drug Discovery, of Burger's Medicinal Chemistry and Drug Discovery, 6th Edition. This new volume contains critical new chapters on Virtual Screening, Bioinformatics and Chemical Information Computing Systems in Drug Discovery. To purchase the entire 6 volume set, please refer to ISBN 0-471-37032-0. For a complete list of articles and contributors as well as FREE sample chapters from this new 6th Edition please visit: www.mrw.interscience.wiley.com/bmcdd

Burger's Medicinal Chemistry and Drug Discovery, Therapeutic Agents

Burger's Medicinal Chemistry and Drug Discovery, Therapeutic Agents PDF Author: Manfred E. Wolff
Publisher: Wiley-Interscience
ISBN: 9780471575573
Category : Science
Languages : en
Pages : 688

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Book Description
The most comprehensive source of the latest information in drug discovery and medicinal chemistry BURGER'S MEDICINAL CHEMISTRY AND DRUG DISCOVERY, FIFTH EDITION, Volume 2: Therapeutic Agents Renowned for its incisive, systematic examination of the new classes of drugs, Burger's Medicinal Chemistry and Drug Discovery provides professionals with thorough, yet selective access to drug chemistry information in a convenient format. Volume 2 outlines the newest generation of drugs with the potential for controlling cardiovascular, gastrointestinal, and tubercular disease. These include: * Cholinergics and anticholinergics * Gastric proton pump inhibitors * Cardiac drugs and antihypertensive agents * Diuretic and urcosuric agents * Aminoglycoside, macrolide, glycopeptide, and other antibacterial antibiotics * Antimycobacterial and antifungal agents The behavior of each drug class is explored in terms of pathophysiology of the disease state, molecular mechanism of action, pharmacokinetics, toxicity, drug metabolism, and structure activity relationships. Special attention is given to fertile areas of further research. Burger's Medicinal Chemistry and Drug Discovery, Volume 2 is an essential reference for medical professionals and researchers working today. Burger's Medicinal Chemistry, Fifth Edition consists of five volumes: Volume 1: Principles and Practice (0-471-57556-9) 1995 " . . . an essential addition to the libraries of any medicinal chemist . . . an outstanding work . . . highly praised as a fountain of information in drug studies and research."--Journal of Medicinal Chemistry * Volume 2: Therapeutic Agents (0-471-57557-7) 1996 * Volume 3: Therapeutic Agents (0-471-57558-5) 1996 * Volume 4: Therapeutic Agents (0-471-57559-3) 1997 * Volume 5: Therapeutic Agents (0-471-57560-7) 1997

Textbook of Drug Design and Discovery, Third Edition

Textbook of Drug Design and Discovery, Third Edition PDF Author: Tommy Liljefors
Publisher: CRC Press
ISBN: 9780415282888
Category : Medical
Languages : en
Pages : 596

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Book Description
Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final processes of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for particular cellular targets such as ion channels and receptors, and also explore specific classes of drug such as peptidomimetics, antivirals and anticancer agents. The use of gene technology in pharmaceutical research, computer modeling techniques, and combinatorial approaches are also included.

An Introduction to Medicinal Chemistry

An Introduction to Medicinal Chemistry PDF Author: Graham L. Patrick
Publisher: Oxford University Press
ISBN: 0198749694
Category : Science
Languages : en
Pages : 911

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Book Description
For many people, taking some form of medication is part of everyday life, whether for mild or severe illness, acute or chronic disease, to target infection or to relieve pain. However for most it remains a mystery as to what happens once the drug has been taken into the body: how do the drugs actually work? Furthermore, by what processes are new drugs discovered and brought to market? An Introduction to Medicinal Chemistry, sixth edition, provides an accessible and comprehensive account of this fascinating multidisciplinary field. Assuming little prior knowledge, the text is ideal for those studying the subject for the first time. Part one of the book introduces the principles of drug action via targets such as receptors and enzymes. The book goes on to explore how drugs work at the molecular level (pharmacodynamics), and the processes involved in ensuring a drug meets its target (pharmacokinetics). Further sections cover the processes by which drugs are discovered and designed, and what has to happen before a drug can be made available to the public. The book concludes with a selection of current topics in medicinal chemistry, and a discussion of various key drug groups. The subject is brought to life throughout by engaging case studies highlighting particular drugs and the stories behind their discovery and development. The Online Resource Centre features: For students: DT Multiple Choice Questions to support self-directed learning DT Web articles describing recent developments in the field and further information on topics covered in the book DT Journal Club to encourage students to critically analyse the research literature DT Molecular Modelling Exercises, with new exercises in Chem3D DT New assignments to help students develop data analysis and problem solving skills For registered adopters of the book: DT A test bank of additional multiple-choice questions, with links to relevant sections in the book DT Answers to end-of-chapter questions. DT Figures from the book, ready to download. DT Power Point slides to accompany every chapter in the book.

Medicinal Chemistry

Medicinal Chemistry PDF Author: Erland Stevens
Publisher: Prentice Hall
ISBN: 9780321710482
Category : Medical
Languages : en
Pages : 418

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Book Description
Emphasizing applications of chemistry while reinforcing theory – especially in the areas of organic and physical chemistry – this new text prepares readers for career success in the pharmaceutical, medical, and biotech industries. Medicinal Chemistry: The Modern Drug Discovery Process delivers a comprehensive introduction to medicinal chemistry at an appropriate level of detail for a diverse range of readers. By highlighting the concepts and skills related to drug discovery, Stevens deepens readers' understanding of the knowledge and techniques necessary for their careers.

Plant Bioactives and Drug Discovery

Plant Bioactives and Drug Discovery PDF Author: Valdir Cechinel-Filho
Publisher: John Wiley & Sons
ISBN: 047058226X
Category : Science
Languages : en
Pages : 600

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Book Description
An in-depth exploration of the applications of plant bioactive metabolites in drug research and development Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important topics in pharmaceutical studies today. With coverage of strategic methods of natural compound isolation, structural manipulation, natural products in clinical trials, quality control, and more, and featuring case studies on medicinal plants, the book serves as a definitive guide to the field of plant biodiversity as it relates to medicine. In addition, chapters on using natural products as drugs that target specific disease areas, including neurological disorders, inflammation, infectious diseases, and cancer, illustrate the myriad possibilities for therapeutic applications. Wide ranging and comprehensive, Plant Bioactives and Drug Discovery also includes important information on marketing, regulations, intellectual property rights, and academic-industry collaboration as they relate to plant-based drug research, making it an essential resource for advanced students and academic and industry professionals working in biochemical, pharmaceutical, and related fields.