Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy PDF Download
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Author: Benjamin Bonavida
Publisher: Springer Science & Business Media
ISBN: 1461470706
Category : Medical
Languages : en
Pages : 271
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Book Description
This volume gives the latest developments in on the mechanisms of cancer cell resistance to apoptotic stimuli, which eventually result in cancer progression and metastasis. One of the main challenges in cancer research is to develop new therapies to combat resistant tumors. The development of new effective therapies will be dependent on delineating the biochemical, molecular, and genetic mechanisms that regulate tumor cell resistance to cytotoxic drug-induced apoptosis. These mechanisms should reveal gene products that directly regulate resistance in order to develop new drugs that target these resistance factors and such new drugs may either be selective or common to various cancers. If successful, new drugs may not be toxic and may be used effectively in combination with subtoxic conventional drugs to achieve synergy and to reverse tumor cell resistance. The research developments presented in this book can be translated to produce better clinical responses to resistant tumors.
Author: Benjamin Bonavida
Publisher: Springer Science & Business Media
ISBN: 1461470706
Category : Medical
Languages : en
Pages : 271
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Book Description
This volume gives the latest developments in on the mechanisms of cancer cell resistance to apoptotic stimuli, which eventually result in cancer progression and metastasis. One of the main challenges in cancer research is to develop new therapies to combat resistant tumors. The development of new effective therapies will be dependent on delineating the biochemical, molecular, and genetic mechanisms that regulate tumor cell resistance to cytotoxic drug-induced apoptosis. These mechanisms should reveal gene products that directly regulate resistance in order to develop new drugs that target these resistance factors and such new drugs may either be selective or common to various cancers. If successful, new drugs may not be toxic and may be used effectively in combination with subtoxic conventional drugs to achieve synergy and to reverse tumor cell resistance. The research developments presented in this book can be translated to produce better clinical responses to resistant tumors.
Author: W. Anthony Sheppard
Publisher: Oxford University Press
ISBN: 0190072717
Category : Music
Languages : en
Pages : 608
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Book Description
To what extent can music be employed to shape one culture's understanding of another? In the American imagination, Japan has represented the "most alien" nation for over 150 years. This perceived difference has inspired fantasies--of both desire and repulsion--through which Japanese culture has profoundly impacted the arts and industry of the U.S. While the influence of Japan on American and European painting, architecture, design, theater, and literature has been celebrated in numerous books and exhibitions, the role of music has been virtually ignored until now. W. Anthony Sheppard's Extreme Exoticism offers a detailed documentation and wide-ranging investigation of music's role in shaping American perceptions of the Japanese, the influence of Japanese music on American composers, and the place of Japanese Americans in American musical life. Presenting numerous American encounters with and representations of Japanese music and Japan, this book reveals how music functions in exotic representation across a variety of genres and media, and how Japanese music has at various times served as a sign of modernist experimentation, a sounding board for defining American music, and a tool for reshaping conceptions of race and gender. From the Tin Pan Alley songs of the Russo-Japanese war period to Weezer's Pinkerton album, music has continued to inscribe Japan as the land of extreme exoticism.
Author: Gayleen Gindy
Publisher: AuthorHouse
ISBN: 1546200592
Category : Art
Languages : en
Pages : 488
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Book Description
Join the author in reliving Sylvania’s over 180 years of history from footpaths to expressways and beyond, in volume six of an eight-volume set. With over 30 years of research, she has included every subject imaginable that helped bring Sylvania to where they are today: with excellent schools, over-the-top parks and recreation, rich beautiful homes, commercial and industrial businesses, and a quaint historical downtown that looks like it was planned by Norman Rockwell himself. This book is a treasure trove of information for the thousands who have ancestors that once lived and helped Sylvania grow through these years. Located in Northwestern Ohio, Sylvania is a suburb of Toledo, Ohio, and for many years has been known as “the fastest growing suburb in Lucas County.” A once-rural farm community between both the city and township, they have grown from a combined 2,220 residents in 1910, to 48,487 in 2010. Over a short period of time, the land has transformed into beautiful subdivisions of grand houses so that now, their subdivision names are all that remain to remind them of their once-dense forests and sprawling farmlands. No longer can Sylvania be called the “bedroom community” of Toledo because over the last 50 years, they have done a lot more than sleep.
Author: Ralph Albert Parlette
Publisher:
ISBN:
Category : Lectures and lecturing
Languages : en
Pages : 952
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Book Description
Author: Gerald D Fasman
Publisher: CRC Press
ISBN: 1351080830
Category : Medical
Languages : en
Pages : 656
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Book Description
This volume contains information on the nucleotide composition of bacterial DNA. Eukaryotic protists, etc.; Nearest neighbour frequencies in DNA; repeated and unique sequences in eukaryotes; nucleic acid sequences in bacteriophage, chloroplasts, mitochondria, kinetoplasts, satellites and TRNA. Information on the physical properties of RNA, atomic coordinates of DNA-DNA. Also included in this volume is information on enzymes involved in nucleic acid function.
Author: Roy Whistler
Publisher: Elsevier
ISBN: 0323144241
Category : Science
Languages : en
Pages : 634
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Book Description
Methods in Carbohydrate Chemistry, Volume VI: General Carbohydrate Methods contains a collection of selected methods from the entire field of carbohydrate chemistry. This volume is comprised of useful procedures in analytical and preparative carbohydrate chemistry. It is organized into 10 sections. The first section deals with methods for separation and analysis, which discusses chromatography and chemical, physical, and biochemical methods. Section II covers the preparation of mono- and polysaccharides and their derivatives. Section III describes a variety of oxidation methods. The fourth section is about procedures for the analysis of acyclic sugars. Sections V and VI present the etherification and esterification of carbohydrates. Nucleotides, nucleosides, and glycoside procedures are described in Sections VII and VIII. The ninth section focuses on radioactively labeled sugars. The final chapter provides a variety of physical methods such as mass spectrometry, nuclear magnetic resonance spectroscopy, and determination of molecular weights by osmometry. Chemists and biochemists will find this book very useful.
Author: British and foreign school society
Publisher:
ISBN:
Category :
Languages : en
Pages : 608
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Book Description
Author: Allen Ronaghan
Publisher: Kitscoty, Alta. : County of Vermilion River
ISBN:
Category : Education
Languages : en
Pages : 666
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Book Description
The county of Vermilion River includes the towns of Vermilion, Kitscoty, Marawayne an Paradise Valley, Alberta.
Author:
Publisher: Wolters Kluwer India Pvt Ltd
ISBN: 9390612535
Category :
Languages : en
Pages :
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Book Description
Author:
Publisher: Academic Press
ISBN: 0080563058
Category : Science
Languages : en
Pages : 403
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Book Description
Advances in Carbohydrate Chemistry and Biochemistry
