Biotechnology Research in an Age of Terrorism

Biotechnology Research in an Age of Terrorism PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309089778
Category : Technology & Engineering
Languages : en
Pages : 164

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Book Description
In recent years much has happened to justify an examination of biological research in light of national security concerns. The destructive application of biotechnology research includes activities such as spreading common pathogens or transforming them into even more lethal forms. Policymakers and the scientific community at large must put forth a vigorous and immediate response to this challenge. This new book by the National Research Council recommends that the government expand existing regulations and rely on self-governance by scientists rather than adopt intrusive new policies. One key recommendation of the report is that the government should not attempt to regulate scientific publishing but should trust scientists and journals to screen their papers for security risks, a task some journals have already taken up. With biological information and tools widely distributed, regulating only U.S. researchers would have little effect. A new International Forum on Biosecurity should encourage the adoption of similar measures around the world. Seven types of risky studies would require approval by the Institutional Biosafety Committees that already oversee recombinant DNA research at some 400 U.S. institutions. These "experiments of concern" include making an infectious agent more lethal and rendering vaccines powerless.

Biotechnology Research in an Age of Terrorism

Biotechnology Research in an Age of Terrorism PDF Author: National Research Council (U.S.). Committee on Research Standards and Practices to Prevent the Destructive Application of Biotechnology
Publisher:
ISBN: 9780309090872
Category :
Languages : en
Pages : 110

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Book Description


Countering Bioterrorism

Countering Bioterrorism PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309086078
Category : Political Science
Languages : en
Pages : 105

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Book Description
The attacks of September 11 and the release of anthrax spores revealed enormous vulnerabilities in the U.S. public-health infrastructure and suggested similar vulnerabilities in the agricultural infrastructure as well. The traditional public health response-surveillance (intelligence), prevention, detection, response, recovery, and attribution-is the paradigm for the national response not only to all forms of terrorism but also to emerging infectious diseases. Thus, investments in research on bioterrorism will have enormous potential for application in the detection, prevention, and treatment of emerging infectious diseases that also are unpredictable and against which we must be prepared. The deciphering of the human genome sequence and the complete elucidation of numerous pathogen genomes, our rapidly increasing understanding of the molecular mechanisms of pathogenesis and of immune responses, and new strategies for designing drugs and vaccines all offer unprecedented opportunities to use science to counter bioterrorist threats. But these same developments also allow science to be misused to create new agents of mass destruction. Hence the effort to confront bioterrorism must be a global one. Countering Bioterrorism makes the following recommendations: Recommendation 1: All agencies with responsibility for homeland security should work together to establish stronger and more meaningful working ties between the intelligence, S&T, and public health communities. Recommendation 2: Federal agencies should work cooperatively and in collaboration with industry to develop and evaluate rapid, sensitive, and specific early-detection technologies. Recommendation 3: Create a global network for detection and surveillance, making use of computerized methods for real-time reporting and analysis to rapidly detect new patterns of disease locally, nationally, and ultimately- internationally. The use of high-throughput methodologies that are being increasingly utilized in modern biological research should be an important component of this expanded and highly automated surveillance strategy. Recommendation 4: Use knowledge of complex biological patterns and high-throughput laboratory automation to classify and diagnose infections in patients in primary care settings. Recommendation 5: USDA should create an agency for control and prevention of plant disease. This agency should have the capabilities necessary to deal effectively with biothreats.

National Security and Arms Control in the Age of Biotechnology

National Security and Arms Control in the Age of Biotechnology PDF Author: Daniel M. Gerstein
Publisher: Rowman & Littlefield Publishers
ISBN: 1442223138
Category : Political Science
Languages : en
Pages : 254

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Book Description
This book accessibly and expertly details the history and implications of the BWC—the Biological and Toxin Weapons Convention—a controversial arms control agreement drafted in the 1970’s meant to supplement the Geneva protocol for warfare from decades earlier. That treaty banned the use of biological weapons in modern warfare, but failed to ban their development, transport or trafficking, holes the BWC aimed to fill, but are still contested to this day. Daniel M. Gerstein, a former Army Colonel and current Under Secretary in the Department of Homeland Security, traces the origins of the treaty and its many complications, past and present, while prescribing a way for the world’s military leaders to move forward with regards to (what Gerstein sees will be and already is) “the most important arms control treaty of the 21st Century.” The strength and enforcement of the treaty are at a crossroads, and it is important for both professionals and students of the military and international affairs to know exactly what a failure to honor, improve and uphold the BWC would mean for international security.

A Survey of Attitudes and Actions on Dual Use Research in the Life Sciences

A Survey of Attitudes and Actions on Dual Use Research in the Life Sciences PDF Author: American Association for the Advancement of Science
Publisher: National Academies Press
ISBN: 030914180X
Category : Political Science
Languages : en
Pages : 189

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Book Description
The same technologies that fuel scientific advances also pose potential risks-that the knowledge, tools, and techniques gained through legitimate biotechnology research could be misused to create biological weapons or for bioterrorism. This is often called the dual use dilemma of the life sciences. Yet even research with the greatest potential for misuse may offer significant benefits. Determining how to constrain the danger without harming essential scientific research is critical for national security as well as prosperity and well-being. This book discusses a 2007 survey of American Association for the Advancement of Science (AAAS) members in the life sciences about their knowledge of dual use issues and attitudes about their responsibilities to help mitigate the risks of misuse of their research. Overall, the results suggest that there may be considerable support for approaches to oversight that rely on measures that are developed and implemented by the scientific community itself. The responses also suggest that there is a need to clarify the scope of research activities of concern and to provide guidance about what actions scientists can take to reduce the risk that their research will be misused by those with malicious intent.

Globalization, Biosecurity, and the Future of the Life Sciences

Globalization, Biosecurity, and the Future of the Life Sciences PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309164753
Category : Science
Languages : en
Pages : 316

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Book Description
Biomedical advances have made it possible to identify and manipulate features of living organisms in useful ways-leading to improvements in public health, agriculture, and other areas. The globalization of scientific and technical expertise also means that many scientists and other individuals around the world are generating breakthroughs in the life sciences and related technologies. The risks posed by bioterrorism and the proliferation of biological weapons capabilities have increased concern about how the rapid advances in genetic engineering and biotechnology could enable the production of biological weapons with unique and unpredictable characteristics. Globalization, Biosecurity, and the Future of Life Sciences examines current trends and future objectives of research in public health, life sciences, and biomedical science that contain applications relevant to developments in biological weapons 5 to 10 years into the future and ways to anticipate, identify, and mitigate these dangers.

Seeking Security

Seeking Security PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309165695
Category : Science
Languages : en
Pages : 88

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Book Description
Within the last 30 years, the genomes of thousands of organisms, from viruses, to bacteria, to humans, have been sequenced or partially sequenced and deposited in databases freely accessible to scientists around the world. This information is accelerating scientists' ability to fight disease and make other medical advances, but policymakers must consider the possibility that the information could also be used for destructive purposes in acts of bioterrorism or war. Based in part on views from working biological scientists, the report concludes that current policies that allow scientists and the public unrestricted access to genome data on microbial pathogens should not be changed. Because access improves our ability to fight both bioterrorism and naturally occurring infectious diseases, security against bioterrorism is better served by policies that facilitate, not limit, the free flow of this information.

Handbook on Biological Warfare Preparedness

Handbook on Biological Warfare Preparedness PDF Author: S.J.S. Flora
Publisher: Academic Press
ISBN: 012812055X
Category : Medical
Languages : en
Pages : 308

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Book Description
Handbook on Biological Warfare Preparedness provides detailed information on biological warfare agents and their mode of transmission and spread. In addition, it explains methods of detection and medical countermeasures, including vaccine and post-exposure therapeutics, with specific sections detailing diseases, their transmission, clinical signs and symptoms, diagnosis, treatment, vaccines, prevention and management. This book is useful reading for researchers and advanced students in toxicology, but it will also prove helpful for medical students, civil administration, medical doctors, first responders and security forces. As the highly unpredictable nature of any event involving biological warfare agents has given rise to the need for the rapid development of accurate detection systems, this book is a timely resource on the topic. - Introduces different bacterial and viral agents, including Ebola and other emerging threats and toxins - Discusses medical countermeasures, including vaccines and post-exposure therapeutics - Includes a comprehensive review of current methods of detection

Bio-Inspired Innovation and National Security

Bio-Inspired Innovation and National Security PDF Author: National Defense University
Publisher: NDU Press
ISBN: 1780390408
Category : History
Languages : en
Pages : 356

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Book Description
Despite the vital importance of the emerging area of biotechnology and its role in defense planning and policymaking, no definitive book has been written on the topic for the defense policymaker, the military student, and the private-sector bioscientist interested in the "emerging opportunities market" of national security. This edited volume is intended to help close this gap and provide the necessary backdrop for thinking strategically about biology in defense planning and policymaking. This volume is about applications of the biological sciences, here called "biologically inspired innovations," to the military. Rather than treating biology as a series of threats to be dealt with, such innovations generally approach the biological sciences as a set of opportunities for the military to gain strategic advantage over adversaries. These opportunities range from looking at everything from genes to brains, from enhancing human performance to creating renewable energy, from sensing the environment around us to harnessing its power.

Biodefense in the Age of Synthetic Biology

Biodefense in the Age of Synthetic Biology PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309465184
Category : Technology & Engineering
Languages : en
Pages : 189

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Book Description
Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.