Bioprocess Intensification

Bioprocess Intensification PDF Author: Dirk Holtmann
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110760371
Category : Science
Languages : en
Pages : 553

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Book Description
Application of Process Intensification (PI) presents a set of radically innovative principles in process and equipment design, which can bring significant benefits in terms of process efficiency, capital and operating expenses, quality, process safety, and sustainability. Typical approaches in bioprocess intensification are the reduction of the number of production steps, continuous processing, integrated processes, and alternative energy inputs.

Bioprocess Intensification

Bioprocess Intensification PDF Author: Dirk Holtmann
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110760371
Category : Science
Languages : en
Pages : 553

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Book Description
Application of Process Intensification (PI) presents a set of radically innovative principles in process and equipment design, which can bring significant benefits in terms of process efficiency, capital and operating expenses, quality, process safety, and sustainability. Typical approaches in bioprocess intensification are the reduction of the number of production steps, continuous processing, integrated processes, and alternative energy inputs.

Bioprocess Intensification

Bioprocess Intensification PDF Author: Dirk Holtmann
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110760339
Category : Science
Languages : en
Pages : 386

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Book Description
Application of Process Intensification (PI) presents a set of radically innovative principles in process and equipment design, which can bring significant benefits in terms of process efficiency, capital and operating expenses, quality, process safety, and sustainability. Typical approaches in bioprocess intensification are the reduction of the number of production steps, continuous processing, integrated processes, and alternative energy inputs.

Intensification of Biobased Processes

Intensification of Biobased Processes PDF Author: Andrzej Górak
Publisher: Royal Society of Chemistry
ISBN: 178801457X
Category : Technology & Engineering
Languages : en
Pages : 482

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Book Description
In recent years bioprocessing has increased in popularity and importance, however, bioprocessing still poses various important techno-economic and environmental challenges, such as product yields, excessive energy consumption for separations in highly watery systems, batch operation or the downstream processing bottlenecks in the production of biopharmaceutical products. Many of those challenges can be addressed by application of different process intensification technologies discussed in the present book. The first book dedicated entirely to this area, Intensification of Biobased Processes provides a comprehensive overview of modern process intensification technologies used in bioprocessing. The book focusses on four different categories of biobased products: bio-fuels and platform chemicals; cosmeceuticals; food products; and polymers and advanced materials. It will cover various intensification aspects of the processes concerned, including (bio)reactor intensification; intensification of separation, recovery and formulation operations; and process integration. This is an invaluable source of information for researchers and industrialists working in chemical engineering, biotechnology and process engineering.

Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing

Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing PDF Author: Ganapathy Subramanian
Publisher: John Wiley & Sons
ISBN: 3527347690
Category : Technology & Engineering
Languages : en
Pages : 404

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Book Description
Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing Explore new trends in continuous biomanufacturing with contributions from leading practitioners in the field With the increasingly widespread acceptance and investment in the ??technology, the last decade has demonstrated the utility of continuous ??processing in the pharmaceutical industry. In Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing, distinguished biotechnologist Dr. Ganapathy Subramanian delivers a comprehensive exploration of the potential of the continuous processing of biological products and discussions of future directions in advancing continuous processing to meet new challenges and demands in the manufacture of therapeutic products. A stand-alone follow-up to the editor’s Continuous Biomanufacturing: Innovative Technologies and Methods published in 2017, this new edited volume focuses on critical aspects of process intensification, process control, and the digital transformation of biopharmaceutical processes. In addition to topics like the use of multivariant data analysis, regulatory concerns, and automation processes, the book also includes: Thorough introductions to capacitance sensors to control feeding strategies and the continuous production of viral vaccines Comprehensive explorations of strategies for the continuous upstream processing of induced microbial systems Practical discussions of preparative hydrophobic interaction chromatography and the design of modern protein-A-resins for continuous biomanufacturing In-depth examinations of bioprocess intensification approaches and the benefits of single use for process intensification Perfect for biotechnologists, bioengineers, pharmaceutical engineers, and process engineers, Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing is also an indispensable resource for chemical engineers seeking a one-stop reference on continuous biomanufacturing.

Process Intensification

Process Intensification PDF Author: Fernando Israel Gómez-Castro
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110592797
Category : Technology & Engineering
Languages : en
Pages : 389

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Book Description
Intensified processes have found widespread application in the chemical and petrochemical industries. The use of intensified systems allows for a reduction of operating costs and supports the "greening" of chemical processes. However, the design of intensified equipment requires special methodologies. This book describes the fundamentals and applications of these design methods, making it a valuable resource for use in both industry and academia.

Process Intensification

Process Intensification PDF Author: David Reay
Publisher: Butterworth-Heinemann
ISBN: 9780080558080
Category : Technology & Engineering
Languages : en
Pages : 472

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Book Description
Process intensification (PI) is a chemical and process design approach that leads to substantially smaller, cleaner, safer and more energy-efficient process technology. A hot topic across the chemical and process industries, this is the first book to provide a practical working guide to understanding and developing successful PI solutions that deliver savings and efficiencies. It will appeal to engineers working with leading-edge process technologies and those involved research and development of chemical, process, environmental, pharmaceutical, and bioscience systems. * Shows chemical and process engineers how to apply process intensification to their system, process or operation * A hard-working reference and user guide to the technology AND application of PI, covering fundamentals, industry applications, supplemented by a development and implementation guide * Leading author team, including Professor Colin Ramshaw, developer of the HiGee high-gravity distillation process at ICI, widely credited as the instigator of PI principles

Improvements in Bio-Based Building Blocks Production Through Process Intensification and Sustainability Concepts

Improvements in Bio-Based Building Blocks Production Through Process Intensification and Sustainability Concepts PDF Author: Juan Gabriel Segovia-Hernandez
Publisher: Elsevier
ISBN: 0323886329
Category : Technology & Engineering
Languages : en
Pages : 252

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Book Description
Improvements in Bio-Based Building Blocks Production Through Process Intensification and Sustainability Concepts discusses new information on the production and cost of bio-based building blocks. From a technical point-of-view, almost all industrial materials made from fossil resources can be substituted using bio-based counterparts. However, the cost of bio-based production in many cases exceeds the cost of petrochemical production. In addition, new products must be proven to perform at least as good as their petrochemical equivalents, have a lower environmental impact, meet consumer demand for environmentally-friendly products, factor in population growth, and account for limited supplies of non-renewables. This book outlines the application of process intensification techniques which allow for the generation of clean, efficient and economical processes for bio-based chemical blocks production. Includes synthesis and process design strategies for intensified processes Describes multi-objective optimization applied to the production of bio-based building blocks Presents the controllability of processes where the production of bio-based building blocks is involved Provides examples using aspen and MATLAB Introduces several sustainable indexes to evaluate production processes Presents process intensification techniques to improve performance in productive processes

Process Intensification in Chemical Engineering

Process Intensification in Chemical Engineering PDF Author: Juan Gabriel Segovia-Hernández
Publisher: Springer
ISBN: 3319283928
Category : Science
Languages : en
Pages : 336

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Book Description
This book will provide researchers and graduate students with an overview of the recent developments and applications of process intensification in chemical engineering. It will also allow the readers to apply the available intensification techniques to their processes and specific problems. The content of this book can be readily adopted as part of special courses on process control, design, optimization and modelling aimed at senior undergraduate and graduate students. This book will be a useful resource for researchers in process system engineering as well as for practitioners interested in applying process intensification approaches to real-life problems in chemical engineering and related areas.

Developments in Sustainable Chemical and Bioprocess Technology

Developments in Sustainable Chemical and Bioprocess Technology PDF Author: Ravindra Pogaku
Publisher: Springer Science & Business Media
ISBN: 1461462088
Category : Science
Languages : en
Pages : 424

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Book Description
Environmental sustainability and development is of critical importance. Technological advances in the production of new energy sources are making their way into our lives in more and more depth every day. However, there is an urgent need to address the technological challenges and advancement of the various chemical and bio-processes to maintain the dynamic sustainability of our energy needs. Toward that end, an attempt is being made to look at recent advances, key issues still faced and where possible, offer suggestions on alternative technologies to optimize sustainable processes. Still considered a new area of science, energy sources themselves are still being 'discovered'...meaning, what is financially viable in the current marketplace is changing. For example, energy from plants has not been financially viable in the past because of the high cost of growing, harvesting, breaking down cell walls, disposal of waste products, etc. Materials used to derive energy from sustainable resources is changing, making previously high-cost processes more efficient. It is crucial that the industry as a while works in tandem to develop crops that new technological advances make financially feasible. This book will cover recent advances in the chemicals, bioprocesses and other materials used in growing and extracting energy from sustainable products. Membrane/cell wall digestion issues will also be covered as well as recovering mamixal amounts of energy from sources to limit waste. Finally a section on safety and control will be presented with has been poorly covered in other publications. ​

Aqueous Two-Phase Systems for Bioprocess Development for the Recovery of Biological Products

Aqueous Two-Phase Systems for Bioprocess Development for the Recovery of Biological Products PDF Author: Marco Rito-Palomares
Publisher: Springer
ISBN: 3319593099
Category : Technology & Engineering
Languages : en
Pages : 191

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Book Description
This comprehensive and unique text presents a full overview of downstream processing useful for those new to the concept as well as professionals with experience in the area. The history and theoretical principles of Aqueous Two-Phase Systems (ATPS) are covered in depth. Information on ATPS characterization and application is included, and ATPS equilibria and system parameters that have significant effect on partition behavior are studied. Aqueous Two-Phase Systems for Bioprocess Development for the Recovery of Biological Products addresses specific applications of ATPS for the recovery and partial purification of high molecular weight compounds such as proteins, nucleic acids and polysaccharides, particulate bioproducts such as cells and organelles and low molecular weight compounds. Non-conventional strategies involving ATPS such as affinity systems, continuous liquid-liquid fractionation stages and the recovery from plant extracts are presented. Economic analysis of the application of ATPS in comparison to other fractionation techniques, particularly liquid chromatography, is considered, as are opportunity and current trends in the ATPS research area. Each chapter utilizes the contributors' experimental expertise in traditional and non-conventional ATPS strategies, as well as analysis of areas of opportunity and perspectives on the development and future applications of ATPS in both the lab and larger scale operations. The result is a thorough and singular overview of ATPS which has not been matched by any other text on the market.