Author: Ganapathy Subramanian
Publisher: John Wiley & Sons
ISBN: 3527347690
Category : Technology & Engineering
Languages : en
Pages : 404
Book Description
Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing Explore new trends in continuous biomanufacturing with contributions from leading practitioners in the field With the increasingly widespread acceptance and investment in the ??technology, the last decade has demonstrated the utility of continuous ??processing in the pharmaceutical industry. In Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing, distinguished biotechnologist Dr. Ganapathy Subramanian delivers a comprehensive exploration of the potential of the continuous processing of biological products and discussions of future directions in advancing continuous processing to meet new challenges and demands in the manufacture of therapeutic products. A stand-alone follow-up to the editor’s Continuous Biomanufacturing: Innovative Technologies and Methods published in 2017, this new edited volume focuses on critical aspects of process intensification, process control, and the digital transformation of biopharmaceutical processes. In addition to topics like the use of multivariant data analysis, regulatory concerns, and automation processes, the book also includes: Thorough introductions to capacitance sensors to control feeding strategies and the continuous production of viral vaccines Comprehensive explorations of strategies for the continuous upstream processing of induced microbial systems Practical discussions of preparative hydrophobic interaction chromatography and the design of modern protein-A-resins for continuous biomanufacturing In-depth examinations of bioprocess intensification approaches and the benefits of single use for process intensification Perfect for biotechnologists, bioengineers, pharmaceutical engineers, and process engineers, Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing is also an indispensable resource for chemical engineers seeking a one-stop reference on continuous biomanufacturing.
Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing
Author: Ganapathy Subramanian
Publisher: John Wiley & Sons
ISBN: 3527347690
Category : Technology & Engineering
Languages : en
Pages : 404
Book Description
Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing Explore new trends in continuous biomanufacturing with contributions from leading practitioners in the field With the increasingly widespread acceptance and investment in the ??technology, the last decade has demonstrated the utility of continuous ??processing in the pharmaceutical industry. In Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing, distinguished biotechnologist Dr. Ganapathy Subramanian delivers a comprehensive exploration of the potential of the continuous processing of biological products and discussions of future directions in advancing continuous processing to meet new challenges and demands in the manufacture of therapeutic products. A stand-alone follow-up to the editor’s Continuous Biomanufacturing: Innovative Technologies and Methods published in 2017, this new edited volume focuses on critical aspects of process intensification, process control, and the digital transformation of biopharmaceutical processes. In addition to topics like the use of multivariant data analysis, regulatory concerns, and automation processes, the book also includes: Thorough introductions to capacitance sensors to control feeding strategies and the continuous production of viral vaccines Comprehensive explorations of strategies for the continuous upstream processing of induced microbial systems Practical discussions of preparative hydrophobic interaction chromatography and the design of modern protein-A-resins for continuous biomanufacturing In-depth examinations of bioprocess intensification approaches and the benefits of single use for process intensification Perfect for biotechnologists, bioengineers, pharmaceutical engineers, and process engineers, Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing is also an indispensable resource for chemical engineers seeking a one-stop reference on continuous biomanufacturing.
Publisher: John Wiley & Sons
ISBN: 3527347690
Category : Technology & Engineering
Languages : en
Pages : 404
Book Description
Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing Explore new trends in continuous biomanufacturing with contributions from leading practitioners in the field With the increasingly widespread acceptance and investment in the ??technology, the last decade has demonstrated the utility of continuous ??processing in the pharmaceutical industry. In Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing, distinguished biotechnologist Dr. Ganapathy Subramanian delivers a comprehensive exploration of the potential of the continuous processing of biological products and discussions of future directions in advancing continuous processing to meet new challenges and demands in the manufacture of therapeutic products. A stand-alone follow-up to the editor’s Continuous Biomanufacturing: Innovative Technologies and Methods published in 2017, this new edited volume focuses on critical aspects of process intensification, process control, and the digital transformation of biopharmaceutical processes. In addition to topics like the use of multivariant data analysis, regulatory concerns, and automation processes, the book also includes: Thorough introductions to capacitance sensors to control feeding strategies and the continuous production of viral vaccines Comprehensive explorations of strategies for the continuous upstream processing of induced microbial systems Practical discussions of preparative hydrophobic interaction chromatography and the design of modern protein-A-resins for continuous biomanufacturing In-depth examinations of bioprocess intensification approaches and the benefits of single use for process intensification Perfect for biotechnologists, bioengineers, pharmaceutical engineers, and process engineers, Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing is also an indispensable resource for chemical engineers seeking a one-stop reference on continuous biomanufacturing.
Intensification of Biobased Processes
Author: Andrzej Gorak
Publisher: Royal Society of Chemistry
ISBN: 1788010329
Category : Science
Languages : en
Pages : 544
Book Description
The first book dedicated entirely to this area, Intensification of Biobased Processes provides a comprehensive overview of modern process intensification technologies used in bioprocessing.
Publisher: Royal Society of Chemistry
ISBN: 1788010329
Category : Science
Languages : en
Pages : 544
Book Description
The first book dedicated entirely to this area, Intensification of Biobased Processes provides a comprehensive overview of modern process intensification technologies used in bioprocessing.
Aqueous Two-Phase Systems for Bioprocess Development for the Recovery of Biological Products
Author: Marco Rito-Palomares
Publisher: Springer
ISBN: 3319593099
Category : Technology & Engineering
Languages : en
Pages : 196
Book Description
This comprehensive and unique text presents a full overview of downstream processing useful for those new to the concept as well as professionals with experience in the area. The history and theoretical principles of Aqueous Two-Phase Systems (ATPS) are covered in depth. Information on ATPS characterization and application is included, and ATPS equilibria and system parameters that have significant effect on partition behavior are studied. Aqueous Two-Phase Systems for Bioprocess Development for the Recovery of Biological Products addresses specific applications of ATPS for the recovery and partial purification of high molecular weight compounds such as proteins, nucleic acids and polysaccharides, particulate bioproducts such as cells and organelles and low molecular weight compounds. Non-conventional strategies involving ATPS such as affinity systems, continuous liquid-liquid fractionation stages and the recovery from plant extracts are presented. Economic analysis of the application of ATPS in comparison to other fractionation techniques, particularly liquid chromatography, is considered, as are opportunity and current trends in the ATPS research area. Each chapter utilizes the contributors' experimental expertise in traditional and non-conventional ATPS strategies, as well as analysis of areas of opportunity and perspectives on the development and future applications of ATPS in both the lab and larger scale operations. The result is a thorough and singular overview of ATPS which has not been matched by any other text on the market.
Publisher: Springer
ISBN: 3319593099
Category : Technology & Engineering
Languages : en
Pages : 196
Book Description
This comprehensive and unique text presents a full overview of downstream processing useful for those new to the concept as well as professionals with experience in the area. The history and theoretical principles of Aqueous Two-Phase Systems (ATPS) are covered in depth. Information on ATPS characterization and application is included, and ATPS equilibria and system parameters that have significant effect on partition behavior are studied. Aqueous Two-Phase Systems for Bioprocess Development for the Recovery of Biological Products addresses specific applications of ATPS for the recovery and partial purification of high molecular weight compounds such as proteins, nucleic acids and polysaccharides, particulate bioproducts such as cells and organelles and low molecular weight compounds. Non-conventional strategies involving ATPS such as affinity systems, continuous liquid-liquid fractionation stages and the recovery from plant extracts are presented. Economic analysis of the application of ATPS in comparison to other fractionation techniques, particularly liquid chromatography, is considered, as are opportunity and current trends in the ATPS research area. Each chapter utilizes the contributors' experimental expertise in traditional and non-conventional ATPS strategies, as well as analysis of areas of opportunity and perspectives on the development and future applications of ATPS in both the lab and larger scale operations. The result is a thorough and singular overview of ATPS which has not been matched by any other text on the market.
Handbook of Microalgae-Based Processes and Products
Author: Eduardo Jacob-Lopes
Publisher: Academic Press
ISBN: 0128185376
Category : Technology & Engineering
Languages : en
Pages : 938
Book Description
The Handbook of Microalgae-based Processes and Products provides a complete overview of all aspects involved in the production and utilization of microalgae resources at commercial scale. Divided into four parts (fundamentals, microalgae-based processes, microalgae-based products, and engineering approaches applied to microalgal processes and products), the book explores the microbiology and metabolic aspects of microalgae, microalgal production systems, wastewater treatment based in microalgae, CO2 capture using microalgae, microalgae harvesting techniques, and extraction and purification of biomolecules from microalgae. It covers the largest number of microalgal products of commercial relevance, including biogas, biodiesel, bioethanol, biohydrogen, single-cell protein, single-cell oil, biofertilizers, pigments, polyunsaturated fatty acids, bioactive proteins, peptides and amino acids, bioactive polysaccharides, sterols, bioplastics, UV-screening compounds, and volatile organic compounds. Moreover, it presents and discusses the available engineering tools applied to microalgae biotechnology, such as process integration, process intensification, and techno-economic analysis applied to microalgal processes and products, microalgal biorefineries, life cycle assessment, and exergy analysis of microalgae-based processes and products. The coverage of a broad range of potential microalgae processes and products in a single volume makes this handbook an indispensable reference for engineering researchers in academia and industry in the fields of bioenergy, sustainable development, and high-value compounds from biomass, as well as graduate students exploring those areas. Engineering professionals in bio-based industries will also find valuable information here when planning or implementing the use of microalgal technologies. - Covers theoretical background information and results of recent research. - Discusses all commercially relevant microalgae-based processes and products. - Explores the main emerging engineering tools applied to microalgae processes, including techno-economic analysis, process integration, process intensification, life cycle assessment, and exergy analyses.
Publisher: Academic Press
ISBN: 0128185376
Category : Technology & Engineering
Languages : en
Pages : 938
Book Description
The Handbook of Microalgae-based Processes and Products provides a complete overview of all aspects involved in the production and utilization of microalgae resources at commercial scale. Divided into four parts (fundamentals, microalgae-based processes, microalgae-based products, and engineering approaches applied to microalgal processes and products), the book explores the microbiology and metabolic aspects of microalgae, microalgal production systems, wastewater treatment based in microalgae, CO2 capture using microalgae, microalgae harvesting techniques, and extraction and purification of biomolecules from microalgae. It covers the largest number of microalgal products of commercial relevance, including biogas, biodiesel, bioethanol, biohydrogen, single-cell protein, single-cell oil, biofertilizers, pigments, polyunsaturated fatty acids, bioactive proteins, peptides and amino acids, bioactive polysaccharides, sterols, bioplastics, UV-screening compounds, and volatile organic compounds. Moreover, it presents and discusses the available engineering tools applied to microalgae biotechnology, such as process integration, process intensification, and techno-economic analysis applied to microalgal processes and products, microalgal biorefineries, life cycle assessment, and exergy analysis of microalgae-based processes and products. The coverage of a broad range of potential microalgae processes and products in a single volume makes this handbook an indispensable reference for engineering researchers in academia and industry in the fields of bioenergy, sustainable development, and high-value compounds from biomass, as well as graduate students exploring those areas. Engineering professionals in bio-based industries will also find valuable information here when planning or implementing the use of microalgal technologies. - Covers theoretical background information and results of recent research. - Discusses all commercially relevant microalgae-based processes and products. - Explores the main emerging engineering tools applied to microalgae processes, including techno-economic analysis, process integration, process intensification, life cycle assessment, and exergy analyses.
Process Intensification Technologies for Green Chemistry
Author: Kamelia Boodhoo
Publisher: John Wiley & Sons
ISBN: 1118498534
Category : Science
Languages : en
Pages : 400
Book Description
The successful implementation of greener chemical processes relies not only on the development of more efficient catalysts for synthetic chemistry but also, and as importantly, on the development of reactor and separation technologies which can deliver enhanced processing performance in a safe, cost-effective and energy efficient manner. Process intensification has emerged as a promising field which can effectively tackle the challenges of significant process enhancement, whilst also offering the potential to diminish the environmental impact presented by the chemical industry. Following an introduction to process intensification and the principles of green chemistry, this book presents a number of intensified technologies which have been researched and developed, including case studies to illustrate their application to green chemical processes. Topics covered include: • Intensified reactor technologies: spinning disc reactors, microreactors, monolith reactors, oscillatory flow reactors, cavitational reactors • Combined reactor/separator systems: membrane reactors, reactive distillation, reactive extraction, reactive absorption • Membrane separations for green chemistry • Industry relevance of process intensification, including economics and environmental impact, opportunities for energy saving, and practical considerations for industrial implementation. Process Intensification for Green Chemistry is a valuable resource for practising engineers and chemists alike who are interested in applying intensified reactor and/or separator systems in a range of industries to achieve green chemistry principles.
Publisher: John Wiley & Sons
ISBN: 1118498534
Category : Science
Languages : en
Pages : 400
Book Description
The successful implementation of greener chemical processes relies not only on the development of more efficient catalysts for synthetic chemistry but also, and as importantly, on the development of reactor and separation technologies which can deliver enhanced processing performance in a safe, cost-effective and energy efficient manner. Process intensification has emerged as a promising field which can effectively tackle the challenges of significant process enhancement, whilst also offering the potential to diminish the environmental impact presented by the chemical industry. Following an introduction to process intensification and the principles of green chemistry, this book presents a number of intensified technologies which have been researched and developed, including case studies to illustrate their application to green chemical processes. Topics covered include: • Intensified reactor technologies: spinning disc reactors, microreactors, monolith reactors, oscillatory flow reactors, cavitational reactors • Combined reactor/separator systems: membrane reactors, reactive distillation, reactive extraction, reactive absorption • Membrane separations for green chemistry • Industry relevance of process intensification, including economics and environmental impact, opportunities for energy saving, and practical considerations for industrial implementation. Process Intensification for Green Chemistry is a valuable resource for practising engineers and chemists alike who are interested in applying intensified reactor and/or separator systems in a range of industries to achieve green chemistry principles.
Bioprospecting of Microorganism-Based Industrial Molecules
Author: Sudhir P. Singh
Publisher: John Wiley & Sons
ISBN: 1119717264
Category : Science
Languages : en
Pages : 452
Book Description
Discover a comprehensive and current overview of microbial bioprospecting written by leading voices in the field In Bioprospecting of Microorganism-Based Industrial Molecules, distinguished researchers and authors Sudhir P. Singh and Santosh Kumar Upadhyay deliver global perspectives of bioprospecting of biodiversity. The book covers diverse aspects of bioprospecting of microorganisms demonstrating biomass value of nutraceutical, pharmaceutical, biomedical, and bioenergetic importance. The authors present an amalgamation of translational research on bioresource utilization and ecological sustainability that will further the reader’s knowledge of the applications of different microbial diversity and reveal new avenues of research investigation. Readers will also benefit from: A thorough introduction to microbial biodiversity and bioprospecting An exploration of anti-ageing and skin lightening microbial products and microbial production of anti-cancerous biomolecules A treatment of UV protective compounds from algal biodiversity and polysaccharides from marine microalgal sources Discussions of microbial sources of insect toxic proteins and the role of microbes in bio-surfactants production Perfect for academics, scientists, researchers, graduate and post-graduate students working and studying in the areas of microbiology, food biotechnology, industrial microbiology, plant biotechnology, and microbial biotechnology, Bioprospecting of Microorganism-Based Industrial Molecules is an indispensable guide for anyone looking for a comprehensive overview of the subject.
Publisher: John Wiley & Sons
ISBN: 1119717264
Category : Science
Languages : en
Pages : 452
Book Description
Discover a comprehensive and current overview of microbial bioprospecting written by leading voices in the field In Bioprospecting of Microorganism-Based Industrial Molecules, distinguished researchers and authors Sudhir P. Singh and Santosh Kumar Upadhyay deliver global perspectives of bioprospecting of biodiversity. The book covers diverse aspects of bioprospecting of microorganisms demonstrating biomass value of nutraceutical, pharmaceutical, biomedical, and bioenergetic importance. The authors present an amalgamation of translational research on bioresource utilization and ecological sustainability that will further the reader’s knowledge of the applications of different microbial diversity and reveal new avenues of research investigation. Readers will also benefit from: A thorough introduction to microbial biodiversity and bioprospecting An exploration of anti-ageing and skin lightening microbial products and microbial production of anti-cancerous biomolecules A treatment of UV protective compounds from algal biodiversity and polysaccharides from marine microalgal sources Discussions of microbial sources of insect toxic proteins and the role of microbes in bio-surfactants production Perfect for academics, scientists, researchers, graduate and post-graduate students working and studying in the areas of microbiology, food biotechnology, industrial microbiology, plant biotechnology, and microbial biotechnology, Bioprospecting of Microorganism-Based Industrial Molecules is an indispensable guide for anyone looking for a comprehensive overview of the subject.
Re-Engineering the Chemical Processing Plant
Author: Andrzej Stankiewicz
Publisher: CRC Press
ISBN: 9780203913291
Category : Technology & Engineering
Languages : en
Pages : 556
Book Description
The first guide to compile current research and frontline developments in the science of process intensification (PI), Re-Engineering the Chemical Processing Plant illustrates the design, integration, and application of PI principles and structures for the development and optimization of chemical and industrial plants. This volume updates professionals on emerging PI equipment and methodologies to promote technological advances and operational efficacy in chemical, biochemical, and engineering environments and presents clear examples illustrating the implementation and application of specific process-intensifying equipment and methods in various commercial arenas.
Publisher: CRC Press
ISBN: 9780203913291
Category : Technology & Engineering
Languages : en
Pages : 556
Book Description
The first guide to compile current research and frontline developments in the science of process intensification (PI), Re-Engineering the Chemical Processing Plant illustrates the design, integration, and application of PI principles and structures for the development and optimization of chemical and industrial plants. This volume updates professionals on emerging PI equipment and methodologies to promote technological advances and operational efficacy in chemical, biochemical, and engineering environments and presents clear examples illustrating the implementation and application of specific process-intensifying equipment and methods in various commercial arenas.
Process Intensification
Author: David Reay
Publisher: Butterworth-Heinemann
ISBN: 0080983057
Category : Technology & Engineering
Languages : en
Pages : 624
Book Description
Process Intensification: Engineering for Efficiency, Sustainability and Flexibility is the first book to provide a practical working guide to understanding process intensification (PI) and developing successful PI solutions and applications in chemical process, civil, environmental, energy, pharmaceutical, biological, and biochemical systems. Process intensification is a chemical and process design approach that leads to substantially smaller, cleaner, safer, and more energy efficient process technology. It improves process flexibility, product quality, speed to market and inherent safety, with a reduced environmental footprint. This book represents a valuable resource for engineers working with leading-edge process technologies, and those involved research and development of chemical, process, environmental, pharmaceutical, and bioscience systems. - No other reference covers both the technology and application of PI, addressing fundamentals, industry applications, and including a development and implementation guide - Covers hot and high growth topics, including emission prevention, sustainable design, and pinch analysis - World-class authors: Colin Ramshaw pioneered PI at ICI and is widely credited as the father of the technology
Publisher: Butterworth-Heinemann
ISBN: 0080983057
Category : Technology & Engineering
Languages : en
Pages : 624
Book Description
Process Intensification: Engineering for Efficiency, Sustainability and Flexibility is the first book to provide a practical working guide to understanding process intensification (PI) and developing successful PI solutions and applications in chemical process, civil, environmental, energy, pharmaceutical, biological, and biochemical systems. Process intensification is a chemical and process design approach that leads to substantially smaller, cleaner, safer, and more energy efficient process technology. It improves process flexibility, product quality, speed to market and inherent safety, with a reduced environmental footprint. This book represents a valuable resource for engineers working with leading-edge process technologies, and those involved research and development of chemical, process, environmental, pharmaceutical, and bioscience systems. - No other reference covers both the technology and application of PI, addressing fundamentals, industry applications, and including a development and implementation guide - Covers hot and high growth topics, including emission prevention, sustainable design, and pinch analysis - World-class authors: Colin Ramshaw pioneered PI at ICI and is widely credited as the father of the technology
Encyclopedia of Chemical Processing
Author: Sunggyu Lee
Publisher: Taylor & Francis US
ISBN: 9780824755003
Category : Science
Languages : en
Pages : 768
Book Description
Supplying nearly 350 expertly-written articles on technologies that can maximize and enhance the research and production phases of current and emerging chemical manufacturing practices and techniques, this second edition provides gold standard articles on the methods, practices, products, and standards recently influencing the chemical industries. New material includes: design of key unit operations involved with chemical processes; design, unit operation, and integration of reactors and separation systems; process system peripherals such as pumps, valves, and controllers; analytical techniques and equipment; current industry practices; and pilot plant design and scale-up criteria.
Publisher: Taylor & Francis US
ISBN: 9780824755003
Category : Science
Languages : en
Pages : 768
Book Description
Supplying nearly 350 expertly-written articles on technologies that can maximize and enhance the research and production phases of current and emerging chemical manufacturing practices and techniques, this second edition provides gold standard articles on the methods, practices, products, and standards recently influencing the chemical industries. New material includes: design of key unit operations involved with chemical processes; design, unit operation, and integration of reactors and separation systems; process system peripherals such as pumps, valves, and controllers; analytical techniques and equipment; current industry practices; and pilot plant design and scale-up criteria.
Bioprocess Intensification
Author: Dirk Holtmann
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110760371
Category : Science
Languages : en
Pages : 553
Book Description
Application of Process Intensification (PI) presents a set of radically innovative principles in process and equipment design, which can bring significant benefits in terms of process efficiency, capital and operating expenses, quality, process safety, and sustainability. Typical approaches in bioprocess intensification are the reduction of the number of production steps, continuous processing, integrated processes, and alternative energy inputs.
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110760371
Category : Science
Languages : en
Pages : 553
Book Description
Application of Process Intensification (PI) presents a set of radically innovative principles in process and equipment design, which can bring significant benefits in terms of process efficiency, capital and operating expenses, quality, process safety, and sustainability. Typical approaches in bioprocess intensification are the reduction of the number of production steps, continuous processing, integrated processes, and alternative energy inputs.