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Author: R. John Solaro
Publisher: Springer Science & Business Media
ISBN: 146147678X
Category : Science
Languages : en
Pages : 254
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Book Description
Subjects in the monograph “Biophysics of the Failing Heart” include state of the art chapters considering major biophysical mechanisms for why hearts responding to acquired or inherited stressors enter into maladaptive processes eventually leading to an inability of the heart to respond efficiently to hemodynamic loads especially during exercise. The chapters describe biophysical techniques that have been applied to determine the triggers for the heart failure process as well as the mechanisms for sustaining the disorders. These techniques include measurements of active and passive mechanical properties and hemodynamics at levels of organization ranging from molecules to hearts beating in situ. Biophysical concepts and approaches are also applied to determination of signaling and signal transduction, energetics, ionic currents, transport processes, electro-chemical and chemo-mechanical coupling. By its emphasis on biophysical aspects of a prevalent clinical condition, the monograph is unique in its perspective and focus. The breadth of information in the chapters all in one place will be of value to clinicians and researchers at all levels. Modern research approaches and clinical understanding of heart failure demands integration of multiple aspects of the disorders. In most cases, combinations of clinician scientists and researchers author the chapters. A main benefit of the book is couched in its didactic approach together with its emphasis on how biophysical concepts and techniques aid in diagnosis and development of new therapies.
Author: R. John Solaro
Publisher: Springer Science & Business Media
ISBN: 146147678X
Category : Science
Languages : en
Pages : 254
Get Book Here
Book Description
Subjects in the monograph “Biophysics of the Failing Heart” include state of the art chapters considering major biophysical mechanisms for why hearts responding to acquired or inherited stressors enter into maladaptive processes eventually leading to an inability of the heart to respond efficiently to hemodynamic loads especially during exercise. The chapters describe biophysical techniques that have been applied to determine the triggers for the heart failure process as well as the mechanisms for sustaining the disorders. These techniques include measurements of active and passive mechanical properties and hemodynamics at levels of organization ranging from molecules to hearts beating in situ. Biophysical concepts and approaches are also applied to determination of signaling and signal transduction, energetics, ionic currents, transport processes, electro-chemical and chemo-mechanical coupling. By its emphasis on biophysical aspects of a prevalent clinical condition, the monograph is unique in its perspective and focus. The breadth of information in the chapters all in one place will be of value to clinicians and researchers at all levels. Modern research approaches and clinical understanding of heart failure demands integration of multiple aspects of the disorders. In most cases, combinations of clinician scientists and researchers author the chapters. A main benefit of the book is couched in its didactic approach together with its emphasis on how biophysical concepts and techniques aid in diagnosis and development of new therapies.
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1380
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Book Description
Author: Jan Strackee
Publisher: CRC Press
ISBN:
Category : Art
Languages : en
Pages : 528
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Book Description
This book is aimed at those working on the physical aspects of heart and circulation. However, the book has a much wider scope: it also presents the physical and mathematical basis for the study of biological systems, not only as a way of thinking but also presenting basic information on all aspects of the cardiovascular system, such as fluid dynamics, elasticity, potential theory, mathematical modelling, etc. The book is of interest to graduate students and researchers in biomedical engineering, medical physics and the clinical sciences.
Author: National Institutes of Health (U.S.). Division of Research Grants
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1414
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Book Description
Author: Jahangir Moini
Publisher: Elsevier
ISBN: 0323959733
Category : Medical
Languages : en
Pages : 600
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Book Description
Neuropsychopharmacology reviews the principles of pharmacology with a focus on the central nervous system and autonomic nervous system. Beyond autonomic and central nervous system pharmacology, this volume uniquely discusses psychiatric disorders and the pharmacological interventions that are available for conditions including depression, schizophrenia and anxiety disorders. With a focus on these specific body systems, readers will see end-of-chapter questions that offer real-world case studies, as well as multiple-choice questions for further learning. Beneficial features and content also include two extensive examination tests, which each contain 100 questions for better learning or to be used in teaching, and a glossary. Helpful appendices cover high-alert medications and toxicology effects on the nervous system. Each chapter will contain classifications of medications, pharmacokinetics, mechanism of action, clinical indications and toxicities. - Describes pharmacology principles pertaining to the central and autonomic nervous system - Identifies pharmacological interventions for psychiatric disorders including current evidence-based interventions for depression, schizophrenia and anxiety disorders - Features chapter outlines, end-of-chapter questions, real-world case studies and examinations for deeper learning or teaching
Author: Markus H. Kuehn
Publisher: Springer Nature
ISBN: 3031423496
Category : Medical
Languages : en
Pages : 331
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Book Description
Since their development a decade ago, human induced pluripotent stem cells (iPSC) have revolutionized the study of human disease, given rise to regenerative medicine technologies, and provided exceptional opportunities for pharmacologic research. These cells provide an essentially unlimited supply of cell types that are difficult to obtain from patients, such as neurons or cardiomyocytes, or are difficult to maintain in primary cell culture. iPSC can be obtained from patients afflicted with a particular disease but, in combination with recently developed gene editing techniques, can also be modified to generate disease models. Moreover, the new techniques of 3 Dimensional printing and materials science facilitate the generation of organoids that can mirror organs under disease conditions. These properties make iPSC powerful tools to study how diseases develop and how they may be treated. In addition, iPSC can also be used to treat conditions in which the target cell population has been lost and such regenerative approaches hold great promise for currently untreatable diseases, including cardiac failure or photoreceptor degenerations.
Author: Jing Zhou
Publisher: Frontiers Media SA
ISBN: 2889717380
Category : Science
Languages : en
Pages : 208
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Book Description
Author: Peter J. Zimetbaum
Publisher: Lippincott Williams & Wilkins
ISBN: 1496371097
Category : Medical
Languages : en
Pages : 600
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Book Description
Now completely revised and in brilliant full color, Practical Clinical Electrophysiology, 2nd Edition, provides a clinically focused, highly readable approach to the diagnosis and management of arrhythmias. Co-authored by Dr. Peter Zimetbaum, Dr. Alfred Buxton and Dr. Mark Josephson, all affiliated with Harvard University, this practical reference offers concise coverage of the major arrhythmia disorders encountered in the clinic as well as the electrophysiology lab, including pharmacologic treatments. It’s an ideal resource for internists, cardiologists, cardiology fellows, and physician extenders who need a complete understanding of electrophysiology but who do not specialize in this area.
Author: David Warrell
Publisher: Oxford University Press
ISBN: 0198717024
Category : Medical
Languages : en
Pages : 689
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Book Description
The Oxford Textbook of Medicine: Cardiovascular Disorders is selected from the cardiology section of the renowned Oxford Textbook of Medicine. An authoritative resource on heart disease and beautifully illustrated in full colour, it is an essential guide to best practice in managing and preventing a wide variety of cardiovascular disorders. Chapters on arrhythmias, acute coronary syndromes and cardiac surgery have been completely revised and updated, together with new chapters on blood vessels and the endotheium, cardiac physiology, syncope and palpitations, and cardio-renal syndrome. Heart failure and heart disease in pregnancy are thoroughly treated, while imaging chapters evaluate the latest techniques and illustrate all clinical features with detailed images. In 46 finely crafted chapters with clear essentials, experts in cardiovascular disease review the essentials of diagnosis, guidelines and practice and provide a wealth of practical advice for use in clinical situations. In addition, background information on epidemiology, pathogenesis and pathophysiology encourages a fuller understanding of conditions, and more than 350 full colour images help with diagnosis. This essential reference tool supports all medical professionals seeking a general outline of treatment and prevention of cardiovascular disorders, and fills the gap between undergraduate teaching texts and specialist texts for cardiologists. Cardiologists and general physicians will find it immensely valuable when diagnosing and managing heart disease in their day-to-day practice. It is also of usefor trainees in cardiology and general medicine, especiallythose interested in applied cardiovascular pathophysiology.
Author: Bernd Nilius
Publisher: Springer
ISBN: 331943814X
Category : Medical
Languages : en
Pages : 141
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Book Description
Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.
