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Author: Mark C. Leake
Publisher: Springer
ISBN: 3319321897
Category : Science
Languages : en
Pages : 364
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Book Description
This book describes modern biophysical techniques that enable us to understand and examine dynamic processes of infection at the molecular level. Cutting-edge research articles, laboratory protocols, case studies and up-to-date reviews cover topics such as single-molecule observation of DNA replication repair pathways in E. coli; evolution of drug resistance in bacteria; restriction enzymes as barriers to horizontal gene transfer in Staphylococcus aureus; infectious and bacterial pathogen biofilms; killing infectious pathogens through DNA damage; bacterial surfaces in host-pathogen interactions; bacterial gene regulation by riboswitches; transcription regulation in enterobacterial pathogens; the bacterial flagellar motor; initial surface colonization by bacteria; Salmonella Typhi host restrictions; as well as monitoring proton motive force in bacteria; microbial pathogens using digital holography; mathematical modelling of microbial pathogen motility; neutron reflectivity in studying bacterial membranes; force spectroscopy in studying infection and 4D multi-photon imaging to investigate immune responses. The focus is on the development and application of complex techniques and protocols at the interface of life sciences and physics, which increase the physiological relevance of biophysical investigations.
Author: Mark C. Leake
Publisher: Springer
ISBN: 3319321897
Category : Science
Languages : en
Pages : 364
Get Book Here
Book Description
This book describes modern biophysical techniques that enable us to understand and examine dynamic processes of infection at the molecular level. Cutting-edge research articles, laboratory protocols, case studies and up-to-date reviews cover topics such as single-molecule observation of DNA replication repair pathways in E. coli; evolution of drug resistance in bacteria; restriction enzymes as barriers to horizontal gene transfer in Staphylococcus aureus; infectious and bacterial pathogen biofilms; killing infectious pathogens through DNA damage; bacterial surfaces in host-pathogen interactions; bacterial gene regulation by riboswitches; transcription regulation in enterobacterial pathogens; the bacterial flagellar motor; initial surface colonization by bacteria; Salmonella Typhi host restrictions; as well as monitoring proton motive force in bacteria; microbial pathogens using digital holography; mathematical modelling of microbial pathogen motility; neutron reflectivity in studying bacterial membranes; force spectroscopy in studying infection and 4D multi-photon imaging to investigate immune responses. The focus is on the development and application of complex techniques and protocols at the interface of life sciences and physics, which increase the physiological relevance of biophysical investigations.
Author: Guillaume Duménil
Publisher: Springer Nature
ISBN: 3030468860
Category : Medical
Languages : en
Pages : 141
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Book Description
This book emerges from the idea that specific physics-inspired approaches are necessary to understand different stage of bacterial physiology and the infections they cause. Many aspects of bacterial life depend on processes typically described by physical laws: The rheology of biofilms is determined by complex cohesive forces. Physical laws of diffusion are essential to all processes of bacterial metabolism. The formation of the numerous bacterial biomacromolecules require complex self-organization processes and their function are powered by potent molecular motors. Host-pathogen interactions during infection frequently occur in environments determined by fluid mechanics. In this book, different chapters represent research at the interface between microbiology and physics. Topics range from intracellular organization to cell-cell interactions. A good part of the book is devoted to mechanical forces, which are involved in the function of elaborate bacterial nanomachines, chromosome segregation, and cell division. The effect of bacterial toxins provides an example of the alteration of cellular membrane properties by bacteria. Symmetrically, histones from mammalian cells alter bacterial membranes as a defense mechanism during infection. The editors of this book, Guillaume Duménil and Sven van Teeffelen, have selected researchers at the forefront of research in physical microbiology to provide the most recent view in this fast-moving field. The contents of this book are designed to be accessible for scientists with training in biology and for scientists with training in physics. The objective is to provide a fresh perspective on microbiology and infection by highlighting recent multidisciplinary research and favor rapid advances at this fruitful interface.
Author: Hans Zinsser
Publisher:
ISBN:
Category : Colloids
Languages : en
Pages : 576
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Book Description
Author: Hans Zinsser
Publisher:
ISBN:
Category :
Languages : en
Pages : 568
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Book Description
Author: John Colter
Publisher: Elsevier
ISBN: 0323142737
Category : Science
Languages : en
Pages : 747
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Book Description
The Molecular Biology of Viruses is a collection of manuscripts presented at the Third Annual International Symposium of the Molecular Biology of Viruses, held in the University of Alberta, Canada on June 27-30, 1966, sponsored by the Faculty of Medicine of the University of Alberta. This book is organized into eight parts encompassing 36 chapters that emphasize the biosynthetic steps involved in polymer duplication. The first two parts explore the specialized processes of the cycle of virulent and temperate bacteriophage multiplication. These parts also deal with the production, regulation of development, and selectivity of these bacteriophages. The subsequent two parts look into the heterozygosity, mutation, structure, function, and mode of infection of single-stranded DNA and RNA bacteriophages. The discussions then shift to the biological and physicochemical aspects, biosynthesis, translation, genetics, and replication of mammalian DNA and RNA viruses. The concluding parts describe the homology, interaction, functions, mechanism of transformation, metabolism, and carcinogenic activity of oncogenic viruses. This book is of great benefit to biochemists, biophysicists, geneticists, microbiologists, and virologists.
Author: Dirk Linke
Publisher: Springer Science & Business Media
ISBN: 9400709404
Category : Medical
Languages : en
Pages : 376
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Book Description
Over the last few years, bacterial adhesion has become a more and more important and active scientific area, but the field lacks communication and scientific exchange between medical and microbiology researchers who work with the relevant biological systems, and biochemists, structural biologists and physicists, who know and understand the physical methods best suited to investigate the phenomenon at the molecular level. The field consequently would benefit from a cross-disciplinary conference enabling such communication. This book tries to bridge the gap between the disciplines.
Author: Hans Zinsser
Publisher:
ISBN:
Category : Colloids
Languages : en
Pages : 690
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Book Description
Author: Bruce Alberts
Publisher:
ISBN: 9780815332183
Category : Cytology
Languages : en
Pages : 0
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Book Description
Author: Hans Zinsser
Publisher: Forgotten Books
ISBN: 9781330381663
Category : Science
Languages : en
Pages : 610
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Book Description
Excerpt from Infection and Resistance, an Exposition of the Biological Phenomena Underlying the Occurrence of Infection and the Recovery of the Animal Body From Infectious Disease Infectious diseases, biologically considered, is the reaction which takes place between invading micro-organisms and their products, on the one hand, and the cells and fluids of the animal's body on the other. The disease is the product of two variable factors, each of them to a certain extent amenable to analysis, and it is self-evident that no true understanding of this branch of medicine is possible without a knowledge of the biological principles which laboratory study has revealed. For the purpose of helping to render such knowledge easily accessible this book was written. While it is hoped that it may prove useful to the practitioner and laboratory worker, it is intended primarily for the undergraduate medical student. To many it will seem that the subject in general and our method of treatment especially are too technical and difficult for this purpose. Our own experience contradicts this. During the past three years the writer has had the opportunity to deliver lectures and to give laboratory courses on this subject to medical students of 2d, 3d, and 4th-year classes at the Stanford and Columbia Universities. It has been a pleasant experience to find the medical student eager for the opportunity to obtain this knowledge and, under the present increased requirements for preliminary training at our best schools, fully capable of assimilating it. It is not a good plan to attempt too extensively to simplify material that, in its close analysis, presents complex phenomena and intricate reasoning. For this reason no attempt has been made to write an A B C of immunity as a quick road to comprehension. No true insight into any branch of medicine or, for that matter, into any other science, can be attained without a certain amount of labor; however the concepts of this subject are, indeed, relatively simple after the first principles have been mastered, and the writer has attempted, therefore, at the risk of seeming pedantic in places, to treat the subject critically, separating strictly those data which may be accepted as fact from those in which legitimate differences of opinion prevail. As far as was feasible every chapter has been written as a separate unit. This has necessitated occasional repetition, but, it is hoped, will add considerably to clearness of presentation in each individual subject. Theories have been discussed with as little prejudice as the possession of a personal opinion in many cases has permitted. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
Author:
Publisher: Academic Press
ISBN: 0128025875
Category : Science
Languages : en
Pages : 468
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Book Description
Virology is in a sense both one of the most important precursors and one of the most significant beneficiaries of structural and cellular molecular biology. Numerous breakthroughs in our understanding of the molecular interactions of viruses with host cells are ready for translation into medically important applications such as the prevention and treatment of viral infections. This book collects a wide variety of examples of frontline research into molecular aspects of viral infections from virological, immunological, cell- and molecular-biological, structural, and theoretical perspectives. Contributors are world leaders in their fields of study and represent prestigious academic and research institutions Review articles vary vastly in scope: some focus on a narrowly defined scientific problem of one particular virus with careful introduction for the non-specialist; others are essays in general and comparative virology with forays into specific viral species or molecules The different perspectives complement each other and collectively the contributions provide an impression of the fast-moving frontlines of virology while showing how the problems have evolved Structural data are presented through high-quality illustrations
