Author: Gary W. Morrow
Publisher: Oxford University Press
ISBN: 0199860521
Category : Science
Languages : en
Pages : 453
Book Description
Building on the foundation of a one-year introductory course in organic chemistry, Bioorganic Synthesis: An Introduction focuses on organic reactions involved in the biosynthesis of naturally-occurring organic compounds with special emphasis on natural products of pharmacological interest. The book is designed specifically for undergraduate students, rather than as an exhaustive reference work for graduate students or professional researchers and is intended to support undergraduate courses for students majoring in chemistry, biochemistry, biology, pre-medicine, and bioengineering programs who would benefit from a deeper understanding of the chemical logic of reactions carried out in organisms and the origins and uses of the important organic compounds they often produce. The book assumes no prior background in biochemistry and consists of eight chapters: i) a brief review of relevant topics from introductory organic chemistry; ii) presentation of essential organic and biochemical reactions used throughout the book along with a brief introduction to coenzymes; iii) review of basic carbohydrates and the biosynthesis of amino acids; iv) the terpenoid pathway for biosynthesis of all important classes of terpenoids and steroids; v) the acetate pathway for biosynthesis of saturated and unsaturated fatty acids, prostaglandins and acetate-derived polyketide natural products; vi) the biosynthesis of the shikimate pathway products derived from aromatic amino acids; vii) an introduction to biosynthesis of major alkaloids and related nitrogenous compounds; and viii) an overview of laboratory organic synthesis as it relates to the challenges faced by synthetic and medicinal chemists who must recreate intricate natural product structures in the laboratory.
Bioorganic Synthesis
Author: Gary W. Morrow
Publisher: Oxford University Press
ISBN: 0199860521
Category : Science
Languages : en
Pages : 453
Book Description
Building on the foundation of a one-year introductory course in organic chemistry, Bioorganic Synthesis: An Introduction focuses on organic reactions involved in the biosynthesis of naturally-occurring organic compounds with special emphasis on natural products of pharmacological interest. The book is designed specifically for undergraduate students, rather than as an exhaustive reference work for graduate students or professional researchers and is intended to support undergraduate courses for students majoring in chemistry, biochemistry, biology, pre-medicine, and bioengineering programs who would benefit from a deeper understanding of the chemical logic of reactions carried out in organisms and the origins and uses of the important organic compounds they often produce. The book assumes no prior background in biochemistry and consists of eight chapters: i) a brief review of relevant topics from introductory organic chemistry; ii) presentation of essential organic and biochemical reactions used throughout the book along with a brief introduction to coenzymes; iii) review of basic carbohydrates and the biosynthesis of amino acids; iv) the terpenoid pathway for biosynthesis of all important classes of terpenoids and steroids; v) the acetate pathway for biosynthesis of saturated and unsaturated fatty acids, prostaglandins and acetate-derived polyketide natural products; vi) the biosynthesis of the shikimate pathway products derived from aromatic amino acids; vii) an introduction to biosynthesis of major alkaloids and related nitrogenous compounds; and viii) an overview of laboratory organic synthesis as it relates to the challenges faced by synthetic and medicinal chemists who must recreate intricate natural product structures in the laboratory.
Publisher: Oxford University Press
ISBN: 0199860521
Category : Science
Languages : en
Pages : 453
Book Description
Building on the foundation of a one-year introductory course in organic chemistry, Bioorganic Synthesis: An Introduction focuses on organic reactions involved in the biosynthesis of naturally-occurring organic compounds with special emphasis on natural products of pharmacological interest. The book is designed specifically for undergraduate students, rather than as an exhaustive reference work for graduate students or professional researchers and is intended to support undergraduate courses for students majoring in chemistry, biochemistry, biology, pre-medicine, and bioengineering programs who would benefit from a deeper understanding of the chemical logic of reactions carried out in organisms and the origins and uses of the important organic compounds they often produce. The book assumes no prior background in biochemistry and consists of eight chapters: i) a brief review of relevant topics from introductory organic chemistry; ii) presentation of essential organic and biochemical reactions used throughout the book along with a brief introduction to coenzymes; iii) review of basic carbohydrates and the biosynthesis of amino acids; iv) the terpenoid pathway for biosynthesis of all important classes of terpenoids and steroids; v) the acetate pathway for biosynthesis of saturated and unsaturated fatty acids, prostaglandins and acetate-derived polyketide natural products; vi) the biosynthesis of the shikimate pathway products derived from aromatic amino acids; vii) an introduction to biosynthesis of major alkaloids and related nitrogenous compounds; and viii) an overview of laboratory organic synthesis as it relates to the challenges faced by synthetic and medicinal chemists who must recreate intricate natural product structures in the laboratory.
Cyclic Peptides
Author: Jesko Koehnke
Publisher: Royal Society of Chemistry
ISBN: 1782625283
Category : Science
Languages : en
Pages : 392
Book Description
This book provides the reader with a comprehensive view of the state-of-the-art of cyclic peptides, from construction to utility in biology and drug discovery.
Publisher: Royal Society of Chemistry
ISBN: 1782625283
Category : Science
Languages : en
Pages : 392
Book Description
This book provides the reader with a comprehensive view of the state-of-the-art of cyclic peptides, from construction to utility in biology and drug discovery.
Highlights in Bioorganic Chemistry
Author: Carsten Schmuck
Publisher: John Wiley & Sons
ISBN: 3527604081
Category : Science
Languages : de
Pages : 600
Book Description
This is a fascinating introduction to the topic. Spanning the spectrum of nucleic acid chemistry, carbohydrates, peptides, molecular recognition, biosynthesis and natural biosynthesis, right up to medical and biophysical chemistry, the book provides advanced students and those already working in the field with a balanced overview. In more than 30 contributions, a new generation of recognized scientists gives an account of the latest research in such areas as * Artificial receptors for the stabilization of ß-sheet structures * Carbohydrate recognition by artificial receptors * Combinatorial chemistry as a tool for the discovery of catalysts * The interaction of NO and peroxynitrite with hemoglobin and myoglobin * Inhibitors against human mast-cell-tryptase as a potential approach to conquering asthma * The selectivity of DNA replication. A readily accessible survey for everyone wishing to stay abreast of developments. With a Foreword by Ronald Breslow.
Publisher: John Wiley & Sons
ISBN: 3527604081
Category : Science
Languages : de
Pages : 600
Book Description
This is a fascinating introduction to the topic. Spanning the spectrum of nucleic acid chemistry, carbohydrates, peptides, molecular recognition, biosynthesis and natural biosynthesis, right up to medical and biophysical chemistry, the book provides advanced students and those already working in the field with a balanced overview. In more than 30 contributions, a new generation of recognized scientists gives an account of the latest research in such areas as * Artificial receptors for the stabilization of ß-sheet structures * Carbohydrate recognition by artificial receptors * Combinatorial chemistry as a tool for the discovery of catalysts * The interaction of NO and peroxynitrite with hemoglobin and myoglobin * Inhibitors against human mast-cell-tryptase as a potential approach to conquering asthma * The selectivity of DNA replication. A readily accessible survey for everyone wishing to stay abreast of developments. With a Foreword by Ronald Breslow.
Bioorganic Chemistry
Author: J. Rohr
Publisher: Springer
ISBN: 3540680241
Category : Science
Languages : en
Pages : 0
Book Description
The first review in this book presents synthetic strategies, biosynthesis and the genetics involved. The second review article, on non-template based multienzyme systems, addresses why polyketides are the most diverse group of natural products, comparing polyketide syntheses with other non-template multienzyme systems. The third review deals with angucycline antibiotics, the largest subgroup of polycyclic aromatic polyketides.
Publisher: Springer
ISBN: 3540680241
Category : Science
Languages : en
Pages : 0
Book Description
The first review in this book presents synthetic strategies, biosynthesis and the genetics involved. The second review article, on non-template based multienzyme systems, addresses why polyketides are the most diverse group of natural products, comparing polyketide syntheses with other non-template multienzyme systems. The third review deals with angucycline antibiotics, the largest subgroup of polycyclic aromatic polyketides.
Organoselenium Compounds in Biology and Medicine
Author: Vimal Kumar Jain
Publisher: Royal Society of Chemistry
ISBN: 1788010299
Category : Science
Languages : en
Pages : 476
Book Description
This book discusses organoselenium chemistry and biology in the context of its therapeutic potential, taking the reader through synthetic techniques, bioactivity and therapeutic applications
Publisher: Royal Society of Chemistry
ISBN: 1788010299
Category : Science
Languages : en
Pages : 476
Book Description
This book discusses organoselenium chemistry and biology in the context of its therapeutic potential, taking the reader through synthetic techniques, bioactivity and therapeutic applications
Introduction to Bioorganic Chemistry and Chemical Biology
Author: David Van Vranken
Publisher: Garland Science
ISBN: 1135054827
Category : Medical
Languages : en
Pages : 504
Book Description
Introduction to Bioorganic Chemistry and Chemical Biology is the first textbook to blend modern tools of organic chemistry with concepts of biology, physiology, and medicine. With a focus on human cell biology and a problems-driven approach, the text explains the combinatorial architecture of biooligomers (genes, DNA, RNA, proteins, glycans, lipids, and terpenes) as the molecular engine for life. Accentuated by rich illustrations and mechanistic arrow pushing, organic chemistry is used to illuminate the central dogma of molecular biology. Introduction to Bioorganic Chemistry and Chemical Biology is appropriate for advanced undergraduate and graduate students in chemistry and molecular biology, as well as those going into medicine and pharmaceutical science.
Publisher: Garland Science
ISBN: 1135054827
Category : Medical
Languages : en
Pages : 504
Book Description
Introduction to Bioorganic Chemistry and Chemical Biology is the first textbook to blend modern tools of organic chemistry with concepts of biology, physiology, and medicine. With a focus on human cell biology and a problems-driven approach, the text explains the combinatorial architecture of biooligomers (genes, DNA, RNA, proteins, glycans, lipids, and terpenes) as the molecular engine for life. Accentuated by rich illustrations and mechanistic arrow pushing, organic chemistry is used to illuminate the central dogma of molecular biology. Introduction to Bioorganic Chemistry and Chemical Biology is appropriate for advanced undergraduate and graduate students in chemistry and molecular biology, as well as those going into medicine and pharmaceutical science.
Bioorganic Chemistry
Author: Ulf Diederichsen
Publisher: John Wiley & Sons
ISBN: 3527296654
Category : Science
Languages : en
Pages : 487
Book Description
The understanding of (patho)physiological processes - the biosynthesis of biomolecules such as enzymes, nucleic acids, and secondary metabolites; the pathways of signaltransduction; or the function of pharmaceutical agents - is of increasing importance not only for drug research but also for the development of new synthetic methods in organic chemistry and biochemistry. In a truly interdisciplinary way bioorganic chemistry unites the central questions of biochemistry, medicinal chemistry, organic chemistry, and spectroscopy. This book fills a void in this rapidly growing field of chemistry and gives a thorough yet understandable introduction for advanced students and researchers alike. Contributions of more than sixty scientists provide a topical overview of recent advances in: drug development based on natural products; the biosynthesis, activity, and application of enzymes; carbohydrates; peptides; nucleic acids; analytical methods in bioorganic chemistry. This book will be an appetizer for all - students and researchers alike - seeking orientation in this fascinating field of chemistry.
Publisher: John Wiley & Sons
ISBN: 3527296654
Category : Science
Languages : en
Pages : 487
Book Description
The understanding of (patho)physiological processes - the biosynthesis of biomolecules such as enzymes, nucleic acids, and secondary metabolites; the pathways of signaltransduction; or the function of pharmaceutical agents - is of increasing importance not only for drug research but also for the development of new synthetic methods in organic chemistry and biochemistry. In a truly interdisciplinary way bioorganic chemistry unites the central questions of biochemistry, medicinal chemistry, organic chemistry, and spectroscopy. This book fills a void in this rapidly growing field of chemistry and gives a thorough yet understandable introduction for advanced students and researchers alike. Contributions of more than sixty scientists provide a topical overview of recent advances in: drug development based on natural products; the biosynthesis, activity, and application of enzymes; carbohydrates; peptides; nucleic acids; analytical methods in bioorganic chemistry. This book will be an appetizer for all - students and researchers alike - seeking orientation in this fascinating field of chemistry.
Quorum Quenching: A Chemical Biological Approach for Microbial Biofilm Mitigation and Drug Development
Author: Naga Raju Maddela
Publisher: Royal Society of Chemistry
ISBN: 1839167610
Category : Science
Languages : en
Pages : 426
Book Description
Publisher: Royal Society of Chemistry
ISBN: 1839167610
Category : Science
Languages : en
Pages : 426
Book Description
Modern Biocatalysis
Author: Gavin Williams
Publisher: Royal Society of Chemistry
ISBN: 1788014537
Category : Science
Languages : en
Pages : 594
Book Description
The synergy between synthetic biology and biocatalysis is emerging as an important trend for future sustainable processes. This book reviews all modern and novel techniques successfully implemented in biocatalysis, in an effort to provide better performing enzymatic systems and novel biosynthetic routes to (non-)natural products. This includes the use of molecular techniques in protein design and engineering, construction of artificial metabolic pathways, and application of computational methods for enzyme discovery and design. Stress is placed on current ‘hot’ topics in biocatalysis, where recent advances in research are defining new grounds in enzyme-catalyzed processes. With contributions from leading academics around the world, this book makes a ground-breaking contribution to this progressive field and is essential reading for graduates and researchers investigating (bio)catalysis, enzyme engineering, chemical biology, and synthetic biology.
Publisher: Royal Society of Chemistry
ISBN: 1788014537
Category : Science
Languages : en
Pages : 594
Book Description
The synergy between synthetic biology and biocatalysis is emerging as an important trend for future sustainable processes. This book reviews all modern and novel techniques successfully implemented in biocatalysis, in an effort to provide better performing enzymatic systems and novel biosynthetic routes to (non-)natural products. This includes the use of molecular techniques in protein design and engineering, construction of artificial metabolic pathways, and application of computational methods for enzyme discovery and design. Stress is placed on current ‘hot’ topics in biocatalysis, where recent advances in research are defining new grounds in enzyme-catalyzed processes. With contributions from leading academics around the world, this book makes a ground-breaking contribution to this progressive field and is essential reading for graduates and researchers investigating (bio)catalysis, enzyme engineering, chemical biology, and synthetic biology.
Handbook of Chemical and Biological Sensors
Author: R.F Taylor
Publisher: CRC Press
ISBN: 9781420050486
Category : Science
Languages : en
Pages : 1248
Book Description
The Handbook of Chemical and Biological Sensors focuses on the development of sensors to recognize substances rather than physical quantities. This fully inclusive book examines devices that use a biological sensing element to detect and measure chemical and biological species as well as those that use a synthetic element to achieve a similar result. A first port of call for anyone with a specific interest, question, or problem relating to this area, this comprehensive source of reference serves as a guide for practicing scientists and as a text for many graduate courses. It presents relevant physics to chemists, chemistry to materials scientists, materials science to electronic engineers, and fabrication technology to all of the above. In addition, the handbook is useful both to newcomers and to experienced researchers who wish to broaden their knowledge of the constituent disciplines of this wide-ranging field.
Publisher: CRC Press
ISBN: 9781420050486
Category : Science
Languages : en
Pages : 1248
Book Description
The Handbook of Chemical and Biological Sensors focuses on the development of sensors to recognize substances rather than physical quantities. This fully inclusive book examines devices that use a biological sensing element to detect and measure chemical and biological species as well as those that use a synthetic element to achieve a similar result. A first port of call for anyone with a specific interest, question, or problem relating to this area, this comprehensive source of reference serves as a guide for practicing scientists and as a text for many graduate courses. It presents relevant physics to chemists, chemistry to materials scientists, materials science to electronic engineers, and fabrication technology to all of the above. In addition, the handbook is useful both to newcomers and to experienced researchers who wish to broaden their knowledge of the constituent disciplines of this wide-ranging field.