Biologie und Epidemiologie der Hormonersatztherapie - Biology and Epidemiology of Hormone Replacement Therapy PDF Download
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Author: M. A. Lewis
Publisher: Springer
ISBN: 9783642421624
Category : Medical
Languages : de
Pages : 0
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Book Description
This volume contains an advanced level discussion on the appropriateness of hormone replacement therapy (HRT) in modern postmenopausal women on the basis of evidence provided by recent epidemiological studies. It addresses all aspects of benefits and risks associated with HRT. It focuses, however, on cancer risk and on risk of breast cancer in particular. The book advocates further epidemiological studies which incorporate pathobiological assessments.
Author: M. A. Lewis
Publisher: Springer Science & Business Media
ISBN: 3540378618
Category : Medical
Languages : de
Pages : 183
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Book Description
This volume contains an advanced level discussion on the appropriateness of hormone replacement therapy (HRT) in modern postmenopausal women on the basis of evidence provided by recent epidemiological studies. It addresses all aspects of benefits and risks associated with HRT. It focuses, however, on cancer risk and on risk of breast cancer in particular. The book advocates further epidemiological studies which incorporate pathobiological assessments.
Author: M. A. Lewis
Publisher: Springer
ISBN: 9783642421624
Category : Medical
Languages : de
Pages : 0
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Book Description
This volume contains an advanced level discussion on the appropriateness of hormone replacement therapy (HRT) in modern postmenopausal women on the basis of evidence provided by recent epidemiological studies. It addresses all aspects of benefits and risks associated with HRT. It focuses, however, on cancer risk and on risk of breast cancer in particular. The book advocates further epidemiological studies which incorporate pathobiological assessments.
Author: P.A. Schubiger
Publisher: Springer Science & Business Media
ISBN: 3540495274
Category : Science
Languages : en
Pages : 348
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Book Description
Personalized medicine employing patient-based tailor-made therapeutic drugs is taking over treatment paradigms in a variety of ?elds in oncology and the central nervous system. The success of such therapies is mainly dependent on ef?cacious therapeutic drugs and a selective imaging probe for identi?cation of potential responders as well as therapy monitoring for an early bene?t assessment. Molecular imaging (MI) is based on the selective and speci?c interaction of a molecular probe with a biological target which is visualized through nuclear, magnetic resonance, near infrared or other methods. Therefore it is the method of choice for patient selection and therapy monitoring as well as for speci?c e- point monitoring in modern drug development. PET (positron emitting tomography), a nuclear medical imaging modality, is ideally suited to produce three-dimensional images of various targets or processes. The rapidly increasing demand for highly selective probes for MI strongly pushes the development of new PET tracers and PET chemistry. ‘PET chemistry’ can be de?ned as the study of positron-emitting compounds regarding their synthesis, structure, composition, reactivity, nuclear properties and processes and their properties in natural and - natural environments. In practice PET chemistry is strongly in?uenced by the unique properties of the radioisotopes used (e. g. , half-life, che- cal reactivity, etc. ) and integrates scienti?c aspects of nuclear-, organic-, inorganic- and biochemistry.
Author: J. Venitz
Publisher: Springer Science & Business Media
ISBN: 3540495290
Category : Medical
Languages : en
Pages : 224
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Book Description
Optimal dose individualization has become more important in improving clinical efficacy and safety. This is due in part to the variability in drug response. Therefore, the role of optimal dose finding in early clinical drug development so as to maximize successful clinical use is emphasized. This book reviews innovative methods, tools and examples of rational drug development strategies, particularly for novel oncological agents.
Author: Hiram S. Cody
Publisher: CRC Press
ISBN: 9781841840345
Category : Medical
Languages : en
Pages : 300
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Book Description
An intuitive, ingenious and powerful technique, sentinel lymph node biopsy has entered clinical practice with astonishing rapidity and now represents a new standard of care for melanoma and breast cancer patients, while showing great promise for the treatment of urologic, colorectal, gynecologic, and head and neck cancers. This text, written by international experts in the technique, provides a clear and comprehensive guide, presenting a detailed overview and discussing the various mapping techniques available and how these are applied in a number of leading institutions. This essential resource for surgical onocologists, pathologists, and specialists in nuclear medicine will also provide key information for those planning to start a sentinel lymph node program.
Author:
Publisher:
ISBN:
Category :
Languages : de
Pages : 0
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Book Description
Author: Essa M. Aleassa
Publisher: Springer Nature
ISBN: 3030380920
Category : Medical
Languages : en
Pages : 275
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Book Description
This book represents a head-to-toe guide for clinicians who are interested in applying real-time near infrared (NIR) imaging for their patients. Expert surgeons from around the globe share their experience with NIR imaging, most commonly performed using indocyanine green (ICG) fluorescence. The chapters are structured to include a brief background, indications for use, followed by a technical description of the procedure. Each chapter is also accompanied by video examples and detailed information about necessary equipment, drug dosing, and alternative techniques. A pitfalls section serves as a “lessons learned” segment to bookend each chapter. Authors represent a comprehensive list of surgical subspecialties ranging from neurosurgery to plastic surgery. While it is not meant to serve as an exhaustive summary of ICG use in surgery, the goal is to highlight the successful use of this technology in a number of settings. As the technology and applications continue to expand, Video Atlas of Intraoperative Applications of Near Infrared Fluorescence Imaging serves as a foundation upon which to build.
Author: Nelly Oudshoorn
Publisher: Routledge
ISBN: 1134873433
Category : Medical
Languages : en
Pages : 210
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Book Description
First Published in 2004. Routledge is an imprint of Taylor & Francis, an informa company.
Author: G. Dallenbach-Hellweg
Publisher: Springer
ISBN: 9783540113270
Category : Medical
Languages : de
Pages : 0
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Book Description
Die Ovarialtumoren gehoren heute mit zu den haufigsten Tumoren des weiblichen Genitale. Ihre morphologische Differentialdiagnostik und die sich darauf aufbauende gezielte Therapie ist aufgrund der Vielfalt dieser Tumoren ungleich viel komplizierter als in anderen Organen. Dement sprechend liegt der Schwerpunkt dieses Buches auf dem Gebiet der Histo pathologie. Spezialkenntnisse insbesondere tiber die selteneren Formen der Ovarialtumoren hangen von groBen Fallzahlen abo Hier ist der inter nationale Erfahrungsaustausch von vorrangiger Bedeutung. Die derzeit weltweit anerkannte histogenetische Klassifikation der WHO erfahrt an hand der Erfahrungen an drei deutschen Frauenkliniken kleine Erganzun gen und Variationen. Einige Lander, Z. B. Israel verfUgen tiber groBe epi demiologische Untersuchungen, deren Ergebnisse korrelierend aufgenom men sind. Zur klinischen Diagnostik wurden in den letzten lahren mo dernste Untersuchungsmt;thoden neu eingefUhrt; ihre Anwendung setzt jedoch individuell anzupassende kritische Indikationsstellungen voraus. AbschlieBend werden die sich sehr differenziert auf der histologischen Diagnostik aufbauenden modernen Moglichkeiten einer gezielten Thera pie der Ovarialtumoren ausfUhrlich diskutiert. Hier steht die Chemothera pie im Vordergrund. 1m Hinblick auf die Frage einer Hormonbehandlung kommt neuerdings auch dem Rezeptornachweis im Tumorgewebe Bedeu tung zu. Diese Zusammenstellung spricht somit gleichermaBen Pathologen, Onkologen und Gynakologen an und will versuchen, gegenseitige Infor mationslticken der Fachexperten auf dem Gesamtgebiet der Problematik der Ovarialtumoren in zumutbarer Klirze zu schlieJ3en. Daher nehmen ge rade die selteneren und bisher weniger bekannten Tumoren in Bild und Text einen verhaltnismaBig breiten Raum ein auf Kosten der hinlanglich bekannten haufigeren Formen, bei denen Spezia1fragen der Differenti- diagnostik aufgrund neuester Erkenntnisse im Vordergrund stehen.
Author: Kenneth D. Weiss
Publisher: John Wiley & Sons
ISBN: 1118044991
Category : Business & Economics
Languages : en
Pages : 326
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Book Description
This bestselling, up-to-date guide shows you how to start your own import/export business, from researching a raw idea to a successful launch to ongoing, profitable business operations. Complete with real-life examples from importers and exporters, it helps you every step of the way, from targeting a market and preparing a business plan to dealing with foreign currencies, shipping procedures, customs requirements, and more. It also shares tips to help you take advantage of NAFTA and other trade pacts, plus online resources to help you start and grow your business.
