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Author: Elena Burlakova
Publisher: CRC Press
ISBN: 9067644315
Category : Science
Languages : en
Pages : 574
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Book Description
This volume discusses questions of free-radical biology and new, modern directions in molecular cytobiology; proteomics and genomics. The book presents articles and reviews on bioantioxidants, synthesis of new compounds, mechanisms of their action and areas of application. Studies on free radical states using ESR technique, biochemistry of regulatory systems and the role of free radicals in radiation disease and cancer development are given special attention. Test results of new drugs for curing malignant tumors and kinetic approaches to the description of disease development and estimation of curative action of medicinal preparations are shown. The book also presents studies in the branch of enzymology, receptor systems, photoreception, in particular. The volume uniquely presents general tendencies in chemistry, biology and medicine kinetically united and attached to free radical mechanisms and other questions under consideration.
Author: Elena Burlakova
Publisher: CRC Press
ISBN: 9067644315
Category : Science
Languages : en
Pages : 574
Get Book Here
Book Description
This volume discusses questions of free-radical biology and new, modern directions in molecular cytobiology; proteomics and genomics. The book presents articles and reviews on bioantioxidants, synthesis of new compounds, mechanisms of their action and areas of application. Studies on free radical states using ESR technique, biochemistry of regulatory systems and the role of free radicals in radiation disease and cancer development are given special attention. Test results of new drugs for curing malignant tumors and kinetic approaches to the description of disease development and estimation of curative action of medicinal preparations are shown. The book also presents studies in the branch of enzymology, receptor systems, photoreception, in particular. The volume uniquely presents general tendencies in chemistry, biology and medicine kinetically united and attached to free radical mechanisms and other questions under consideration.
Author: Lee A. Segel
Publisher: Cambridge University Press
ISBN: 9780521391849
Category : Mathematics
Languages : en
Pages : 234
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Book Description
This book demonstrates how an understanding of biological kinetics can lead to knowledge about the biological model being examined.
Author: Péter Érdi
Publisher: Springer
ISBN: 149390387X
Category : Science
Languages : en
Pages : 174
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Book Description
This volume reviews the theory and simulation methods of stochastic kinetics by integrating historical and recent perspectives, presents applications, mostly in the context of systems biology and also in combustion theory. In recent years, due to the development in experimental techniques, such as optical imaging, single cell analysis, and fluorescence spectroscopy, biochemical kinetic data inside single living cells have increasingly been available. The emergence of systems biology brought renaissance in the application of stochastic kinetic methods.
Author: Daniel L. Purich
Publisher: Elsevier
ISBN: 0080521932
Category : Science
Languages : en
Pages : 811
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Book Description
Biochemical kinetics refers to the rate at which a reaction takes place. Kinetic mechanisms have played a major role in defining the metabolic pathways, the mechanistic action of enzymes, and even the processing of genetic material. The Handbook of Biochemical Kinetics provides the "underlying scaffolding" of logic for kinetic approaches to distinguish rival models or mechanisms. The handbook also comments on techniques and their likely limitations and pitfalls, as well as derivations of fundamental rate equations that characterize biochemical processes. Key Features* Over 750 pages devoted to theory and techniques for studying enzymic and metabolic processes* Over 1,500 definitions of kinetic and mechanistic terminology, with key references* Practical advice on experimental design of kinetic experiments* Extended step-by-step methods for deriving rate equations* Over 1,000 enzymes, complete with EC numbers, reactions catalyzed, and references to reviews and/or assay methods* Over 5,000 selected references to kinetic methods appearing in the Methods in Enzymology series* 72-page Wordfinder that allows the reader to search by keywords* Summaries of mechanistic studies on key enzymes and protein systems* Over 250 diagrams, figures, tables, and structures
Author: Clive R. Bagshaw
Publisher: CRC Press
ISBN: 1351646664
Category : Medical
Languages : en
Pages : 883
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Book Description
"a gem of a textbook which manages to produce a genuinely fresh, concise yet comprehensive guide" –Mark Leake, University of York "destined to become a standard reference.... Not just a ‘how to’ handbook but also an accessible primer in the essentials of kinetic theory and practice." –Michael Geeves, University of Kent "covers the entire spectrum of approaches, from the traditional steady state methods to a thorough account of transient kinetics and rapid reaction techniques, and then on to the new single molecule techniques" –Stephen Halford, University of Bristol This illustrated treatment explains the methods used for measuring how much a reaction gets speeded up, as well as the framework for solving problems such as ligand binding and macromolecular folding, using the step-by-step approach of numerical integration. It is a thoroughly modern text, reflecting the recent ability to observe reactions at the single-molecule level, as well as advances in microfluidics which have given rise to femtoscale studies. Kinetics is more important now than ever, and this book is a vibrant and approachable entry for anyone who wants to understand mechanism using transient or single molecule kinetics without getting bogged down in advanced mathematics. Clive R. Bagshaw is Emeritus Professor at the University of Leicester, U.K., and Research Associate at the University of California at Santa Cruz, U.S.A.
Author: Terrell L. Hill
Publisher: Courier Corporation
ISBN: 0486150658
Category : Science
Languages : en
Pages : 130
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Book Description
This three-part treatment translates the technical language of research monographs on the theory of free energy transfer in biology, making the subject more accessible to those entering the field. Designed for upper-level classes in biochemistry or biophysics, it can also be used for independent study. 36 figures. 1989 edition.
Author: Gordon G. Hammes
Publisher: John Wiley & Sons
ISBN: 0471374911
Category : Science
Languages : en
Pages : 189
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Book Description
Gain a working knowledge of thermodynamics and kinetics with a minimum of mathematics-a guide for individuals in the biological sciences An understanding of thermodynamics and kinetics is essential for researchers investigating molecular phenomena in diverse disciplines, including bioorganic chemistry, medicinal chemistry, biochemistry, pharmaceuticals, and biology. The use of these physical chemistry tools in the biological sciences has exploded over the past fifteen years, but the majority of works on thermodynamics and kinetics require mathematical expertise beyond that of many researchers in the field. Presenting a highly accessible introduction to thermodynamics and kinetics, Thermodynamics and Kinetics for the Biological Sciences employs a minimum of mathematics, assuming only a basic calculus background, while treating a wide range of topics in a logical and easy-to-follow style. All principles and concepts are clearly illustrated through the use of relevant applications and examples from the biological sciences, and explanations are further enhanced with problems and up-to-date references. Written by a world-renowned authority on biochemical kinetics, this remarkable book also features an easy-to-understand statistical development of entropy and a more extensive coverage of chemical kinetics and ligand binding to macromolecules than is usually found in books of this kind. Readers will acquire a working knowledge of thermodynamics and kinetics that they can readily apply to biological systems and use for exploring the scientific literature.
Author: Quentin Vanhaelen
Publisher: Humana
ISBN: 9781071617694
Category : Science
Languages : en
Pages : 0
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Book Description
This detailed book provides an overview of various classes of computational techniques, including machine learning techniques, commonly used for evaluating kinetic parameters of biological systems. Focusing on three distinct situations, the volume covers the prediction of the kinetics of enzymatic reactions, the prediction of the kinetics of protein-protein or protein-ligand interactions (binding rates, dissociation rates, binding affinities), and the prediction of relatively large set of kinetic rates of reactions usually found in quantitative models of large biological networks. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of expert implementation advice that leads to successful results. Authoritative and practical, Computational Methods for Estimating the Kinetic Parameters of Biological Systems will be of great interest for researchers working through the challenge of identifying the best type of algorithm and who would like to use or develop a computational method for the estimation of kinetic parameters.
Author: H. Gutfreund
Publisher: Cambridge University Press
ISBN: 9780521485869
Category : Medical
Languages : en
Pages : 364
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Book Description
The aim of the book is to introduce the reader to the kinetic analysis of a wide range of biological processes at the molecular level. It is intended to show that the same approach can be used to resolve the number of steps in enzyme reactions, muscle contraction, visual perception and ligand binding receptors that trigger other physiological processes. Attention is also given to methods for characterizing these steps in chemical terms. Although the treatment is mainly theoretical, a wide range of examples and experimental techniques are also introduced and an historical approach is used to demonstrate the development of the theory and experimental techniques of kinetic analysis in biology.
Author: James Andrew Goodrich
Publisher: CSHL Press
ISBN: 0879697369
Category : Carrier proteins
Languages : en
Pages : 188
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Book Description
This handbook offers a practical guide to the principles of quantitative analysis in biological experiments. The material is primarily aimed at working molecular biologists, but the scope and clarity of presentation make it equally suitable as an introduction for students. Topics covered range from the basics — such as measuring the concentrations of macromolecules — through considerations of binding constants and the kinetics of molecular interactions. The book ends with a thorough consideration of data analysis.
