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Author: Jun Lin
Publisher: Frontiers Media SA
ISBN: 2832517730
Category : Science
Languages : en
Pages : 120
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Book Description
Author: Jun Lin
Publisher: Frontiers Media SA
ISBN: 2832517730
Category : Science
Languages : en
Pages : 120
Get Book Here
Book Description
Author: Stephen F. Badylak
Publisher: Woodhead Publishing
ISBN: 0128214562
Category : Technology & Engineering
Languages : en
Pages : 296
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Book Description
Biomaterials have existed for millennia as mechanical replacement structures following disease or injury. Biomaterial design has changed markedly from structural support with an "inert immune profile as the primary objective to designs that elicit an integrative local tissue response and a pro-repair immune cell phenotype. Immunomodulatory Biomaterials: Regulating the Immune Response with Biomaterials to Affect Clinical Outcome offers a single, comprehensive reference on biomaterials for modulation of the host response, for materials scientists, tissue engineers and those working in regenerative medicine. This book details methods, materials and strategies designed to regulate the host immune response following surgical implantation and thus facilitate specific local cell infiltration and tissue deposition. There has been a dramatic transformation in our understanding of the role of the immune system, both innate and adaptive; these changes include recognition of the plasticity of immune cells, especially macrophages, cross-talk between the immune system and stem cells, and the necessity for in situ transition between inflammatory and regulatory immune cell phenotypes. The exploitation of these findings and the design and manufacture of new biomaterials is occurring at an astounding pace. There is currently no book directed at the interdisciplinary principles guiding the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response. The challenge for academia, industry, and regulatory agencies to encourage innovation while assuring safety and maximizing efficacy has never been greater. Given the highly interdisciplinary requirements for the design, manufacture and use of immunomodulatory biomaterials, this book will prove a useful single resource across disciplines. - Holistically covers the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response - Provides a single reference for understanding and utilizing the host response in biomaterials design - An international collaboration of leading researchers in the field offering a novel insight into this fast-growing area
Author: William S. Pietrzak
Publisher: Springer Science & Business Media
ISBN: 1597452394
Category : Medical
Languages : en
Pages : 647
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Book Description
The repair of musculoskeletal tissue is a vital concern of all surgical specialties, orthopedics and related disciplines. Written by recognized experts, this book aims to provide both basic and advanced knowledge of the newer methodologies being developed and introduced to the clinical arena. A valuable resource for researchers, developers, and clinicians, the book presents a foundation to propel the technology and integration of the current state of knowledge into the 21st century.
Author: Kendell Pawelec
Publisher: Woodhead Publishing
ISBN: 0081024525
Category : Technology & Engineering
Languages : en
Pages : 506
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Book Description
Bone Repair Biomaterials: Regeneration and Clinical Applications, Second Edition, provides comprehensive reviews on materials science, engineering principles and recent advances. Sections review the fundamentals of bone repair and regeneration, discuss the science and properties of biomaterials used for bone repair, including metals, ceramics, polymers and composites, and discuss clinical applications and considerations, with chapters on such topics as orthopedic surgery, tissue engineering, implant retrieval, and ethics of bone repair biomaterials. This second edition includes more chapters on relevant biomaterials and a greatly expanded section on clinical applications, including bone repair applications in dental surgery, spinal surgery, and maxilo-facial and skull surgery. In addition, the book features coverage of long-term performance and failure of orthopedic devices. It will be an invaluable resource for researchers, scientists and clinicians concerned with the repair and restoration of bone. - Provides a comprehensive review of the materials science, engineering principles and recent advances in this important area - Presents new chapters on Surface coating of titanium, using bone repair materials in dental, spinal and maxilo-facial and skull surgery, and advanced manufacturing/3D printing - Reviews the fundamentals of bone repair and regeneration, addressing social, economic and clinical challenges - Examines the properties of biomaterials used for bone repair, with specific chapters assessing metals, ceramics, polymers and composites
Author: Mehdi Razavi
Publisher: Academic Press
ISBN: 0128202629
Category : Science
Languages : en
Pages : 290
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Book Description
Nanoengineering in Musculoskeletal Regeneration provides the reader an updated summary of the therapeutic pipeline-from biomedical discovery to clinical implementation-aimed at improving treatments for patients with conditions of the muscles, tendons, cartilage, meniscus, and bone. Regenerative medicine focuses on using stem cell biology to advance medical therapies for devastating disorders. This text presents novel, significant, and interdisciplinary theoretical and experimental results related to nanoscience and nanotechnology in musculoskeletal regeneration. Content includes basic, translational, and clinical research addressing musculoskeletal repair and regeneration for the treatment of diseases and injuries of the skeleton and its associated tissues.Musculoskeletal degeneration and complications from injuries have become more prevalent as people live longer and increasingly participate in rigorous athletic and recreational activities. Additionally, defects in skeletal tissues may immobilize people and cause inflammation and pain. Musculoskeletal regeneration research provides solutions to repair, restore, or replace skeletal elements and associated tissues that are affected by acute injury, chronic degeneration, genetic dysfunction, and cancer-related defects. The goal of musculoskeletal regeneration medicine research is to improve quality of life and outcomes for people with musculoskeletal injury or degradation.
Author: Heimo Ylänen
Publisher: Woodhead Publishing
ISBN: 0081009372
Category : Technology & Engineering
Languages : en
Pages : 428
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Book Description
Bioactive Glasses: Materials, Properties and Applications, Second Edition provides revised, expanded and updated content on the current status of this unique material, including its properties, technologies and applications. The book is suitable for those active in the biomaterials and bioengineering field, and includes eight new chapters that cover material types, computational modeling, coatings and applications. Chapters deal with the materials and mechanical properties of bioactive glass and the applications of bioactive glasses, covering their uses in wound healing, maxillofacial surgery and bone tissue engineering, among other topics. With its distinguished editor and expert team of international contributors, the book is an invaluable reference for researchers and scientists in the field of biomaterials, both in academia and industry. - Provides a detailed review of bioactive glasses, their properties, technologies and applications - Comprehensively covers the materials and mechanical properties of bioactive glass and their further applications, including wound healing, maxillofacial surgery and bone tissue engineering - Suitable for those active in the biomaterials and bioengineering field
Author: Kevin Healy
Publisher: Elsevier
ISBN: 0081006926
Category : Technology & Engineering
Languages : en
Pages : 4865
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Book Description
Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications
Author: Dominique G. Poitout
Publisher: Springer Science & Business Media
ISBN: 9781852334819
Category : Medical
Languages : en
Pages : 694
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Book Description
Current clinical orthopedic practice requires practitioners to have extensive knowledge of a wide range of disciplines from molecular biology to bioengineering and from the application of new methods to the evaluation of outcome. The biomechanics of and biomaterials used in orthopedics have become increasingly important as the possibilities have increased to treat patients with foreign material introduced both as optimized osteosynthesis after trauma and as arthroplasties for joint diseases, sequelae of trauma or for tumor treatment. Furthermore, biomaterial substitutes are constantly being developed to replace missing tissue. Biomechanics and Biomaterials in Orthopedics provides an important update within this highly important field. Professor Dominique Poitout has collected a series of high-quality chapters by globally renowned researchers and clinicians. Under the auspices of the International Society of Orthopaedic Surgery and Traumatology (SICOT) and International Society of Orthopaedic and Traumatology Research (SIROT), this book now provides permanent and specific access to the considerable international knowledge in the field of locomotor system trauma and disease treatment using the novel bioengineering solutions. This book covers both basic concepts concerning biomaterials and biomechanics as well as their clinical application and the experience from everyday practical use. This book will be of great value to specialists in orthopedics and traumatology, while also provide an important basis for graduate and postgraduate learning.
Author: Anuj Kumar
Publisher: CRC Press
ISBN: 1000912086
Category : Medical
Languages : en
Pages : 325
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Book Description
Discusses design chemistry, modification, and processing of biomaterials Describes the efficacy of biomaterials at various scales for biological response and drug delivery Demonstrates technological advances from conventional to additive manufacturing Covers future of biofabrication and customized medical devices
Author: Bikramjit Basu
Publisher: John Wiley & Sons
ISBN: 0470891300
Category : Technology & Engineering
Languages : en
Pages : 778
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Book Description
Enables readers to take full advantage of the latest advances in biomaterials and their applications. Advanced Biomaterials: Fundamentals, Processing, and Applications reviews the latest biomaterials discoveries, enabling readers to take full advantage of the most recent findings in order to advance the biomaterials research and development. Reflecting the nature of biomaterials research, the book covers a broad range of disciplines, including such emerging topics as nanobiomaterials, interface tissue engineering, the latest manufacturing techniques, and new polymeric materials. The book, a contributed work, features a team of renowned scientists, engineers, and clinicians from around the world whose expertise spans the many disciplines needed for successful biomaterials development. All readers will gain an improved understanding of the full range of disciplines and design methodologies that are used to develop biomaterials with the physical and biological properties needed for specific clinical applications.
