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Author: Michael A. Schmidt, Ph.D.
Publisher: North Atlantic Books
ISBN: 9781556437779
Category : Health & Fitness
Languages : en
Pages : 460
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Book Description
At a time when the numbers of emerging infections and antibiotic-resistant bacteria are rising sharply, the supply of new antibiotic drugs has been steadily decreasing. In addition, many health providers have failed to consider that our bodies are cloaked in a blanket of bacteria so pervasive that the bacterial cells outnumber our “human” cells by a factor of ten. In short, we are living in a microbe’s world and cannot ignore the very real potential for untreatable serious infections. In this timely book, Dr. Michael Schmidt proposes we focus on strengthening ourselves by thinking of our bodies as a “human-microbe hybrid.” This requires taking action to raise our defenses, while preserving the integrity of the microbial elements that live on and within us. Drawing on the latest research from several scientific fields, Schmidt presents a strategy of medicine that can be used to build and balance our system of immune defense and repair. He offers a set of general recommendations that can easily be used to tailor programs to individuals seeking to support health maintenance, prevent illness, fight active acute or chronic infections, and foster faster recovery from infections.
Author: Michael A. Schmidt, Ph.D.
Publisher: North Atlantic Books
ISBN: 9781556437779
Category : Health & Fitness
Languages : en
Pages : 460
Get Book Here
Book Description
At a time when the numbers of emerging infections and antibiotic-resistant bacteria are rising sharply, the supply of new antibiotic drugs has been steadily decreasing. In addition, many health providers have failed to consider that our bodies are cloaked in a blanket of bacteria so pervasive that the bacterial cells outnumber our “human” cells by a factor of ten. In short, we are living in a microbe’s world and cannot ignore the very real potential for untreatable serious infections. In this timely book, Dr. Michael Schmidt proposes we focus on strengthening ourselves by thinking of our bodies as a “human-microbe hybrid.” This requires taking action to raise our defenses, while preserving the integrity of the microbial elements that live on and within us. Drawing on the latest research from several scientific fields, Schmidt presents a strategy of medicine that can be used to build and balance our system of immune defense and repair. He offers a set of general recommendations that can easily be used to tailor programs to individuals seeking to support health maintenance, prevent illness, fight active acute or chronic infections, and foster faster recovery from infections.
Author: Michael A. Schmidt
Publisher: North Atlantic Books
ISBN: 9781556431807
Category : Health & Fitness
Languages : en
Pages : 364
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Book Description
With 50 pages of new material, the latest edition of this guide presents additional evidence that modern medicine's continuing reliance on antibiotics as a prime weapon against illness deserves rethinking. Here the authors suggest many natural methods to strengthen the body's immune system.
Author: Isabella S. Oehry
Publisher: Balboa Press
ISBN: 1982239239
Category : Health & Fitness
Languages : en
Pages : 131
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Book Description
HEALING LYME BEYOND ANTIBIOTICS Lyme disease is now the most common tick-borne disease in Europe, Asia, and the United States: according to the CDC, each year in the US alone there are an estimated 300, 000 cases of Lyme disease. As researchers work to find ways to combat Borrelia burgdorferi and other bacteria known to cause Lyme disease, practitioners of allopathic medicine currently have few options beyond antibiotics to offer patients. After becoming very ill with Lyme disease, unsuccessful treatments with antibiotics left Isa extremely weak, exhausted, unable to think clearly, or function normally. A chance remark by her niece about a natural remedy inspired Isa to investigate alternative healing methods. After an extensive search she found the treatment she needed and recovered fully. Healing Lyme Beyond Antibiotics tells the story of Isa’s successful recovery, but is more than a guide on how to cure oneself from Lyme disease by natural means. It also informs the reader about the bacteria that cause the illness, offers detailed information about bacterial hosts and reservoirs, and gives advice on how to protect oneself from getting infected. – a must read book for everyone afflicted with Lyme disease –
Author: Scott H. Podolsky
Publisher: JHU Press
ISBN: 0801889286
Category : Medical
Languages : en
Pages : 448
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Book Description
“Uses [pneumonia] as a vehicle for examining the evolution of therapeutics in America between the ‘Golden Age of Microbiology’ and the ‘Age of Antibiotics.’”—Isis Focusing largely on the treatment of pneumonia in first half of the century with type-specific serotherapy, clinician-historian Scott H. Podolsky provides insight into the rise and clinical evaluation of therapeutic “specifics,” the contested domains of private practice and public health, and—as the treatment of pneumonia made the transition from serotherapy to chemotherapy and antibiotics—the tempo and mode of therapeutic change itself. Type-specific serotherapy, founded on the tenets of applied immunology, justified by controlled clinical trials, and grounded in a novel public ethos, was deemed revolutionary when it emerged to replace supportive therapeutics. With the advent of the even more revolutionary sulfa drugs and antibiotics, pneumonia ceased to be a public health concern and became instead an illness treated in individual patients by individual physicians. Podolsky describes the new therapeutics and the scientists and practitioners who developed and debated them. He finds that, rather than representing a barren era in anticipation of some unknown transformation to come, the first decades of the twentieth-century shaped the use of, and reliance upon, the therapeutic specific throughout the century and beyond. This intriguing study will interest historians of medicine and science, policymakers, and clinicians alike. “Podolsky’s scholarship is awesome, and his grasp of the philosophical and sociologic context of the issues considered make this an important work.” —New England Journal of Medicine “This thoroughly documented, carefully written book is a landmark analysis . . . It should be read by everyone who is involved in research and therapeutic development.” —JAMA
Author: William Rosen
Publisher: Penguin
ISBN: 0698184106
Category : Medical
Languages : en
Pages : 370
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Book Description
The epic history of how antibiotics were born, saving millions of lives and creating a vast new industry known as Big Pharma. As late as the 1930s, virtually no drug intended for sickness did any good; doctors could set bones, deliver babies, and offer palliative care. That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections. William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria—and their ability to rapidly evolve into new forms—the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born. Timely, engrossing, and eye-opening, Miracle Cure is a must-read science narrative—a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity’s relationship with nature since the invention of agriculture ten thousand years ago.
Author: Pilar García Suárez
Publisher: MDPI
ISBN: 3039434047
Category : Science
Languages : en
Pages : 390
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Book Description
There is talk of an upcoming antibiotic armageddon, with untreatable post-operative infections, and similarly untreatable complications after chemotherapy. Indeed, the now famous “O’Neill Report” (https://amr-review.org/) suggests that, by 2050, more people might die from antibiotic-resistant bacterial infections than from cancer. While we are still learning all the subtle drivers of antibiotic resistance, it seems increasingly clear that we need to take a “one health” approach, curtailing the use of antibiotics in both human and veterinary medicine. However, there are no new classes of antibiotics on our horizon. Maybe something that has been around “forever” can come to our rescue—bacteriophages! Nevertheless, it is also necessary to do things differently, and use these new antimicrobials appropriately. Therefore, an in-depth study of bacteriophage biology and case-by-case applications might be required. Whilst by no means comprehensive, this book does cover some of the many topics related to bacteriophages as antimicrobials, including their use in human therapy and aquaculture. It also explores the potential use of phage endolysins as substitutes of antibiotics in two sectors where there is an urgent need—human therapy and the agro-food industry. Last but not least, there is an excellent perspective article on phage therapy implementation.
Author: Martin J. Blaser, MD
Publisher: Henry Holt and Company
ISBN: 0805098119
Category : Science
Languages : en
Pages : 289
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Book Description
“In Missing Microbes, Martin Blaser sounds [an] alarm. He patiently and thoroughly builds a compelling case that the threat of antibiotic overuse goes far beyond resistant infections.”—Nature Renowned microbiologist Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the equilibrium and health of our bodies. Now this invisible Eden is under assault from our overreliance on medical advances including antibiotics and caesarian sections, threatening the extinction of our irreplaceable microbes and leading to severe health consequences. Taking us into the lab to recount his groundbreaking studies, Blaser not only provides elegant support for his theory, he guides us to what we can do to avoid even more catastrophic health problems in the future. “Missing Microbes is science writing at its very best—crisply argued and beautifully written, with stunning insights about the human microbiome and workable solutions to an urgent global crisis.”—David M. Oshinsky, author of the Pulitzer Prize-winning Polio: An American Story
Author: Thomas J. Dougherty
Publisher: Springer Science & Business Media
ISBN: 1461414008
Category : Medical
Languages : en
Pages : 1119
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Book Description
This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.
Author: David M. Shlaes
Publisher: Springer Science & Business Media
ISBN: 9048190576
Category : Medical
Languages : en
Pages : 108
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Book Description
Antibiotics are truly miracle drugs. As a class, they are one of the only ones that actually cure disease as opposed to most drugs that only help relieve symptoms or control disease. Since bacteria that cause serious disease in humans are becoming more and more resistant to the antibiotics we have today, and because they will ultimately become resistant to any antibiotic that we use for treatment or for anything else, we need a steady supply of new antibiotics active against any resistant bacteria that arise. However, the antibiotics marketplace is no longer attractive for large pharmaceutical companies, the costs of development are skyrocketing because of ever more stringent requirements by the regulatory agencies, and finding new antibiotics active against resistant strains is getting harder and harder. These forces are all combining to deny us these miracle drugs when we need them the most. I provide a number of possible paths to shelter from this perfect storm.
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309672104
Category : Medical
Languages : en
Pages : 427
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Book Description
Among the many who serve in the United States Armed Forces and who are deployed to distant locations around the world, myriad health threats are encountered. In addition to those associated with the disruption of their home life and potential for combat, they may face distinctive disease threats that are specific to the locations to which they are deployed. U.S. forces have been deployed many times over the years to areas in which malaria is endemic, including in parts of Afghanistan and Iraq. Department of Defense (DoD) policy requires that antimalarial drugs be issued and regimens adhered to for deployments to malaria-endemic areas. Policies directing which should be used as first and as second-line agents have evolved over time based on new data regarding adverse events or precautions for specific underlying health conditions, areas of deployment, and other operational factors At the request of the Veterans Administration, Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis assesses the scientific evidence regarding the potential for long-term health effects resulting from the use of antimalarial drugs that were approved by FDA or used by U.S. service members for malaria prophylaxis, with a focus on mefloquine, tafenoquine, and other antimalarial drugs that have been used by DoD in the past 25 years. This report offers conclusions based on available evidence regarding associations of persistent or latent adverse events.
