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Author: Dipak K. Dey
Publisher: CRC Press
ISBN: 1420070185
Category : Mathematics
Languages : en
Pages : 468
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Book Description
Bayesian Modeling in Bioinformatics discusses the development and application of Bayesian statistical methods for the analysis of high-throughput bioinformatics data arising from problems in molecular and structural biology and disease-related medical research, such as cancer. It presents a broad overview of statistical inference, clustering, and c
Author: Dipak K. Dey
Publisher: CRC Press
ISBN: 1420070185
Category : Mathematics
Languages : en
Pages : 468
Get Book Here
Book Description
Bayesian Modeling in Bioinformatics discusses the development and application of Bayesian statistical methods for the analysis of high-throughput bioinformatics data arising from problems in molecular and structural biology and disease-related medical research, such as cancer. It presents a broad overview of statistical inference, clustering, and c
Author: Thomas Hamelryck
Publisher: Springer
ISBN: 3642272258
Category : Medical
Languages : en
Pages : 399
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Book Description
This book is an edited volume, the goal of which is to provide an overview of the current state-of-the-art in statistical methods applied to problems in structural bioinformatics (and in particular protein structure prediction, simulation, experimental structure determination and analysis). It focuses on statistical methods that have a clear interpretation in the framework of statistical physics, rather than ad hoc, black box methods based on neural networks or support vector machines. In addition, the emphasis is on methods that deal with biomolecular structure in atomic detail. The book is highly accessible, and only assumes background knowledge on protein structure, with a minimum of mathematical knowledge. Therefore, the book includes introductory chapters that contain a solid introduction to key topics such as Bayesian statistics and concepts in machine learning and statistical physics.
Author: Dirk Husmeier
Publisher: Springer Science & Business Media
ISBN: 1846281199
Category : Computers
Languages : en
Pages : 511
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Book Description
Probabilistic Modelling in Bioinformatics and Medical Informatics has been written for researchers and students in statistics, machine learning, and the biological sciences. The first part of this book provides a self-contained introduction to the methodology of Bayesian networks. The following parts demonstrate how these methods are applied in bioinformatics and medical informatics. All three fields - the methodology of probabilistic modeling, bioinformatics, and medical informatics - are evolving very quickly. The text should therefore be seen as an introduction, offering both elementary tutorials as well as more advanced applications and case studies.
Author: Brian J. Reich
Publisher: CRC Press
ISBN: 0429510918
Category : Mathematics
Languages : en
Pages : 288
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Book Description
Bayesian Statistical Methods provides data scientists with the foundational and computational tools needed to carry out a Bayesian analysis. This book focuses on Bayesian methods applied routinely in practice including multiple linear regression, mixed effects models and generalized linear models (GLM). The authors include many examples with complete R code and comparisons with analogous frequentist procedures. In addition to the basic concepts of Bayesian inferential methods, the book covers many general topics: Advice on selecting prior distributions Computational methods including Markov chain Monte Carlo (MCMC) Model-comparison and goodness-of-fit measures, including sensitivity to priors Frequentist properties of Bayesian methods Case studies covering advanced topics illustrate the flexibility of the Bayesian approach: Semiparametric regression Handling of missing data using predictive distributions Priors for high-dimensional regression models Computational techniques for large datasets Spatial data analysis The advanced topics are presented with sufficient conceptual depth that the reader will be able to carry out such analysis and argue the relative merits of Bayesian and classical methods. A repository of R code, motivating data sets, and complete data analyses are available on the book’s website. Brian J. Reich, Associate Professor of Statistics at North Carolina State University, is currently the editor-in-chief of the Journal of Agricultural, Biological, and Environmental Statistics and was awarded the LeRoy & Elva Martin Teaching Award. Sujit K. Ghosh, Professor of Statistics at North Carolina State University, has over 22 years of research and teaching experience in conducting Bayesian analyses, received the Cavell Brownie mentoring award, and served as the Deputy Director at the Statistical and Applied Mathematical Sciences Institute.
Author: Richard E. Neapolitan
Publisher: Morgan Kaufmann
ISBN: 0080919367
Category : Mathematics
Languages : en
Pages : 421
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Book Description
The Bayesian network is one of the most important architectures for representing and reasoning with multivariate probability distributions. When used in conjunction with specialized informatics, possibilities of real-world applications are achieved. Probabilistic Methods for BioInformatics explains the application of probability and statistics, in particular Bayesian networks, to genetics. This book provides background material on probability, statistics, and genetics, and then moves on to discuss Bayesian networks and applications to bioinformatics. Rather than getting bogged down in proofs and algorithms, probabilistic methods used for biological information and Bayesian networks are explained in an accessible way using applications and case studies. The many useful applications of Bayesian networks that have been developed in the past 10 years are discussed. Forming a review of all the significant work in the field that will arguably become the most prevalent method in biological data analysis. - Unique coverage of probabilistic reasoning methods applied to bioinformatics data--those methods that are likely to become the standard analysis tools for bioinformatics. - Shares insights about when and why probabilistic methods can and cannot be used effectively; - Complete review of Bayesian networks and probabilistic methods with a practical approach.
Author: Osvaldo A. Martin
Publisher: CRC Press
ISBN: 1000520048
Category : Business & Economics
Languages : en
Pages : 421
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Book Description
Bayesian Modeling and Computation in Python aims to help beginner Bayesian practitioners to become intermediate modelers. It uses a hands on approach with PyMC3, Tensorflow Probability, ArviZ and other libraries focusing on the practice of applied statistics with references to the underlying mathematical theory. The book starts with a refresher of the Bayesian Inference concepts. The second chapter introduces modern methods for Exploratory Analysis of Bayesian Models. With an understanding of these two fundamentals the subsequent chapters talk through various models including linear regressions, splines, time series, Bayesian additive regression trees. The final chapters include Approximate Bayesian Computation, end to end case studies showing how to apply Bayesian modelling in different settings, and a chapter about the internals of probabilistic programming languages. Finally the last chapter serves as a reference for the rest of the book by getting closer into mathematical aspects or by extending the discussion of certain topics. This book is written by contributors of PyMC3, ArviZ, Bambi, and Tensorflow Probability among other libraries.
Author: David Barber
Publisher: Cambridge University Press
ISBN: 0521196760
Category : Computers
Languages : en
Pages : 432
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Book Description
The first unified treatment of time series modelling techniques spanning machine learning, statistics, engineering and computer science.
Author: Mohammad Saber Fallah Nezhad
Publisher: BoD – Books on Demand
ISBN: 1789230926
Category : Mathematics
Languages : en
Pages : 142
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Book Description
This book is an introduction to the mathematical analysis of Bayesian decision-making when the state of the problem is unknown but further data about it can be obtained. The objective of such analysis is to determine the optimal decision or solution that is logically consistent with the preferences of the decision-maker, that can be analyzed using numerical utilities or criteria with the probabilities assigned to the possible state of the problem, such that these probabilities are updated by gathering new information.
Author: Osvaldo Martin
Publisher:
ISBN: 9781785883804
Category : Bayesian statistical decision theory
Languages : en
Pages : 282
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Book Description
Unleash the power and flexibility of the Bayesian frameworkAbout This Book- Simplify the Bayes process for solving complex statistical problems using Python; - Tutorial guide that will take the you through the journey of Bayesian analysis with the help of sample problems and practice exercises; - Learn how and when to use Bayesian analysis in your applications with this guide.Who This Book Is ForStudents, researchers and data scientists who wish to learn Bayesian data analysis with Python and implement probabilistic models in their day to day projects. Programming experience with Python is essential. No previous statistical knowledge is assumed.What You Will Learn- Understand the essentials Bayesian concepts from a practical point of view- Learn how to build probabilistic models using the Python library PyMC3- Acquire the skills to sanity-check your models and modify them if necessary- Add structure to your models and get the advantages of hierarchical models- Find out how different models can be used to answer different data analysis questions - When in doubt, learn to choose between alternative models.- Predict continuous target outcomes using regression analysis or assign classes using logistic and softmax regression.- Learn how to think probabilistically and unleash the power and flexibility of the Bayesian frameworkIn DetailThe purpose of this book is to teach the main concepts of Bayesian data analysis. We will learn how to effectively use PyMC3, a Python library for probabilistic programming, to perform Bayesian parameter estimation, to check models and validate them. This book begins presenting the key concepts of the Bayesian framework and the main advantages of this approach from a practical point of view. Moving on, we will explore the power and flexibility of generalized linear models and how to adapt them to a wide array of problems, including regression and classification. We will also look into mixture models and clustering data, and we will finish with advanced topics like non-parametrics models and Gaussian processes. With the help of Python and PyMC3 you will learn to implement, check and expand Bayesian models to solve data analysis problems.Style and approachBayes algorithms are widely used in statistics, machine learning, artificial intelligence, and data mining. This will be a practical guide allowing the readers to use Bayesian methods for statistical modelling and analysis using Python.
Author: Kim-Anh Do
Publisher: Cambridge University Press
ISBN: 052186092X
Category : Mathematics
Languages : en
Pages : 437
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Book Description
Expert overviews of Bayesian methodology, tools and software for multi-platform high-throughput experimentation.
