Bayesian Methods in Structural Bioinformatics PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Bayesian Methods in Structural Bioinformatics PDF full book. Access full book title Bayesian Methods in Structural Bioinformatics by Thomas Hamelryck. Download full books in PDF and EPUB format.
Author: Thomas Hamelryck
Publisher: Springer
ISBN: 3642272258
Category : Medical
Languages : en
Pages : 399
Get Book Here
Book Description
This book is an edited volume, the goal of which is to provide an overview of the current state-of-the-art in statistical methods applied to problems in structural bioinformatics (and in particular protein structure prediction, simulation, experimental structure determination and analysis). It focuses on statistical methods that have a clear interpretation in the framework of statistical physics, rather than ad hoc, black box methods based on neural networks or support vector machines. In addition, the emphasis is on methods that deal with biomolecular structure in atomic detail. The book is highly accessible, and only assumes background knowledge on protein structure, with a minimum of mathematical knowledge. Therefore, the book includes introductory chapters that contain a solid introduction to key topics such as Bayesian statistics and concepts in machine learning and statistical physics.
Author: Thomas Hamelryck
Publisher: Springer
ISBN: 3642272258
Category : Medical
Languages : en
Pages : 399
Get Book Here
Book Description
This book is an edited volume, the goal of which is to provide an overview of the current state-of-the-art in statistical methods applied to problems in structural bioinformatics (and in particular protein structure prediction, simulation, experimental structure determination and analysis). It focuses on statistical methods that have a clear interpretation in the framework of statistical physics, rather than ad hoc, black box methods based on neural networks or support vector machines. In addition, the emphasis is on methods that deal with biomolecular structure in atomic detail. The book is highly accessible, and only assumes background knowledge on protein structure, with a minimum of mathematical knowledge. Therefore, the book includes introductory chapters that contain a solid introduction to key topics such as Bayesian statistics and concepts in machine learning and statistical physics.
Author: Dipak K. Dey
Publisher: CRC Press
ISBN: 1420070185
Category : Mathematics
Languages : en
Pages : 468
Get Book Here
Book Description
Bayesian Modeling in Bioinformatics discusses the development and application of Bayesian statistical methods for the analysis of high-throughput bioinformatics data arising from problems in molecular and structural biology and disease-related medical research, such as cancer. It presents a broad overview of statistical inference, clustering, and c
Author: Zoltán Gáspári
Publisher: Humana
ISBN: 9781071602690
Category : Science
Languages : en
Pages : 0
Get Book Here
Book Description
This volume looks at the latest techniques used to perform comparative structure analyses, and predict and evaluate protein-ligand interactions. The chapters in this book cover tools and servers such as LiteMol; Bio3D-Web; DALI; CATH; HoTMuSiC, a contact-base protein structure analysis tool known as CAD-Score; PyDockSaxs and HADDOCK; CombDock and DockStar; the BioMagResBank database; as well as BME and CoNSEnsX+. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible computational protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Structural Bioinformatics: Methods and Protocols is a practical guide for researchers to learn more about the aforementioned tools to further enhance their studies in the growing field of structural bioinformatics. Chapter 13 is available open access under a CC-BY 4.0 license via link.springer.com.
Author: Kim-Anh Do
Publisher: Cambridge University Press
ISBN: 052186092X
Category : Mathematics
Languages : en
Pages : 437
Get Book Here
Book Description
Expert overviews of Bayesian methodology, tools and software for multi-platform high-throughput experimentation.
Author: Richard E. Neapolitan
Publisher: Morgan Kaufmann
ISBN: 0080919367
Category : Mathematics
Languages : en
Pages : 421
Get Book Here
Book Description
The Bayesian network is one of the most important architectures for representing and reasoning with multivariate probability distributions. When used in conjunction with specialized informatics, possibilities of real-world applications are achieved. Probabilistic Methods for BioInformatics explains the application of probability and statistics, in particular Bayesian networks, to genetics. This book provides background material on probability, statistics, and genetics, and then moves on to discuss Bayesian networks and applications to bioinformatics. Rather than getting bogged down in proofs and algorithms, probabilistic methods used for biological information and Bayesian networks are explained in an accessible way using applications and case studies. The many useful applications of Bayesian networks that have been developed in the past 10 years are discussed. Forming a review of all the significant work in the field that will arguably become the most prevalent method in biological data analysis. - Unique coverage of probabilistic reasoning methods applied to bioinformatics data--those methods that are likely to become the standard analysis tools for bioinformatics. - Shares insights about when and why probabilistic methods can and cannot be used effectively; - Complete review of Bayesian networks and probabilistic methods with a practical approach.
Author: Dongqing Wei
Publisher: Springer
ISBN: 9401792453
Category : Science
Languages : en
Pages : 380
Get Book Here
Book Description
This text examines in detail mathematical and physical modeling, computational methods and systems for obtaining and analyzing biological structures, using pioneering research cases as examples. As such, it emphasizes programming and problem-solving skills. It provides information on structure bioinformatics at various levels, with individual chapters covering introductory to advanced aspects, from fundamental methods and guidelines on acquiring and analyzing genomics and proteomics sequences, the structures of protein, DNA and RNA, to the basics of physical simulations and methods for conformation searches. This book will be of immense value to researchers and students in the fields of bioinformatics, computational biology and chemistry. Dr. Dongqing Wei is a Professor at the Department of Bioinformatics and Biostatistics, College of Life Science and Biotechnology, Shanghai Jiaotong University, Shanghai, China. His research interest is in the general area of structural bioinformatics.
Author: Ian L. Dryden
Publisher: John Wiley & Sons
ISBN: 1118866614
Category : Mathematics
Languages : en
Pages : 432
Get Book Here
Book Description
A timely collection of advanced, original material in the area of statistical methodology motivated by geometric problems, dedicated to the influential work of Kanti V. Mardia This volume celebrates Kanti V. Mardia's long and influential career in statistics. A common theme unifying much of Mardia’s work is the importance of geometry in statistics, and to highlight the areas emphasized in his research this book brings together 16 contributions from high-profile researchers in the field. Geometry Driven Statistics covers a wide range of application areas including directional data, shape analysis, spatial data, climate science, fingerprints, image analysis, computer vision and bioinformatics. The book will appeal to statisticians and others with an interest in data motivated by geometric considerations. Summarizing the state of the art, examining some new developments and presenting a vision for the future, Geometry Driven Statistics will enable the reader to broaden knowledge of important research areas in statistics and gain a new appreciation of the work and influence of Kanti V. Mardia.
Author: Christophe Ley
Publisher: CRC Press
ISBN: 1351856529
Category : Mathematics
Languages : en
Pages : 400
Get Book Here
Book Description
This book collects important advances in methodology and data analysis for directional statistics. It is the companion book of the more theoretical treatment presented in Modern Directional Statistics (CRC Press, 2017). The field of directional statistics has received a lot of attention due to demands from disciplines such as life sciences or machine learning, the availability of massive data sets requiring adapted statistical techniques, and technological advances. This book covers important progress in bioinformatics, biology, astrophysics, oceanography, environmental sciences, earth sciences, machine learning and social sciences.
Author: Osvaldo Martin
Publisher:
ISBN: 9781785883804
Category : Bayesian statistical decision theory
Languages : en
Pages : 282
Get Book Here
Book Description
Unleash the power and flexibility of the Bayesian frameworkAbout This Book- Simplify the Bayes process for solving complex statistical problems using Python; - Tutorial guide that will take the you through the journey of Bayesian analysis with the help of sample problems and practice exercises; - Learn how and when to use Bayesian analysis in your applications with this guide.Who This Book Is ForStudents, researchers and data scientists who wish to learn Bayesian data analysis with Python and implement probabilistic models in their day to day projects. Programming experience with Python is essential. No previous statistical knowledge is assumed.What You Will Learn- Understand the essentials Bayesian concepts from a practical point of view- Learn how to build probabilistic models using the Python library PyMC3- Acquire the skills to sanity-check your models and modify them if necessary- Add structure to your models and get the advantages of hierarchical models- Find out how different models can be used to answer different data analysis questions - When in doubt, learn to choose between alternative models.- Predict continuous target outcomes using regression analysis or assign classes using logistic and softmax regression.- Learn how to think probabilistically and unleash the power and flexibility of the Bayesian frameworkIn DetailThe purpose of this book is to teach the main concepts of Bayesian data analysis. We will learn how to effectively use PyMC3, a Python library for probabilistic programming, to perform Bayesian parameter estimation, to check models and validate them. This book begins presenting the key concepts of the Bayesian framework and the main advantages of this approach from a practical point of view. Moving on, we will explore the power and flexibility of generalized linear models and how to adapt them to a wide array of problems, including regression and classification. We will also look into mixture models and clustering data, and we will finish with advanced topics like non-parametrics models and Gaussian processes. With the help of Python and PyMC3 you will learn to implement, check and expand Bayesian models to solve data analysis problems.Style and approachBayes algorithms are widely used in statistics, machine learning, artificial intelligence, and data mining. This will be a practical guide allowing the readers to use Bayesian methods for statistical modelling and analysis using Python.
Author: Clair L. Alston
Publisher: John Wiley & Sons
ISBN: 1118394321
Category : Mathematics
Languages : en
Pages : 411
Get Book Here
Book Description
Provides an accessible foundation to Bayesian analysis using real world models This book aims to present an introduction to Bayesian modelling and computation, by considering real case studies drawn from diverse fields spanning ecology, health, genetics and finance. Each chapter comprises a description of the problem, the corresponding model, the computational method, results and inferences as well as the issues that arise in the implementation of these approaches. Case Studies in Bayesian Statistical Modelling and Analysis: Illustrates how to do Bayesian analysis in a clear and concise manner using real-world problems. Each chapter focuses on a real-world problem and describes the way in which the problem may be analysed using Bayesian methods. Features approaches that can be used in a wide area of application, such as, health, the environment, genetics, information science, medicine, biology, industry and remote sensing. Case Studies in Bayesian Statistical Modelling and Analysis is aimed at statisticians, researchers and practitioners who have some expertise in statistical modelling and analysis, and some understanding of the basics of Bayesian statistics, but little experience in its application. Graduate students of statistics and biostatistics will also find this book beneficial.
