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Author: J. Andrew Armour
Publisher: Oxford University Press
ISBN: 9780199775194
Category : Medical
Languages : en
Pages : 492
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Book Description
The progression of heart disease is associated with changes in the neurohumoral mechanisms that control cardiac function. The degree to which this neurohumoral remodeling occurs, even before overt signs of cardiac disease become manifest, is important for prognosis. To determine why some patients experience sudden death while others sustain life in the presence of severely compromised cardiac function, the neuronal control of cardiac electrical and mechanical events must be considered. Starting at the level of individual neurons and building upwards, this book describes the synergistic interactions that occur among intrathoracic and CNS feedback loops to permit precise control of regional cardiac behavior. On this basic science foundation, subsequent clinical chapters explore the remodeling that occurs in this system with aging, with the evolution of specific cardiac pathologies, and with the psychological concomitants of heart disease. Most importantly, these chapters provide unique insights into how specific therapies like beta-andrenergic receptor blockade not only affect cardiomyocytes directly but also mitigate the adverse neurohumoral changes that accompany disease processes, such as heart failure and essential hypertension. The paradigm advanced in this volume is that heart disease is a multifaceted phenomenon involving the interplay of neurohumoral, cardiomyocyte and structural elements, each of which depends on the other. With our cumulative understanding of these interdependent processes, new avenues for time-appropriate, targeted methods of treating heart diseases can be developed.
Author: J. Andrew Armour
Publisher: Oxford University Press
ISBN: 9780199775194
Category : Medical
Languages : en
Pages : 492
Get Book Here
Book Description
The progression of heart disease is associated with changes in the neurohumoral mechanisms that control cardiac function. The degree to which this neurohumoral remodeling occurs, even before overt signs of cardiac disease become manifest, is important for prognosis. To determine why some patients experience sudden death while others sustain life in the presence of severely compromised cardiac function, the neuronal control of cardiac electrical and mechanical events must be considered. Starting at the level of individual neurons and building upwards, this book describes the synergistic interactions that occur among intrathoracic and CNS feedback loops to permit precise control of regional cardiac behavior. On this basic science foundation, subsequent clinical chapters explore the remodeling that occurs in this system with aging, with the evolution of specific cardiac pathologies, and with the psychological concomitants of heart disease. Most importantly, these chapters provide unique insights into how specific therapies like beta-andrenergic receptor blockade not only affect cardiomyocytes directly but also mitigate the adverse neurohumoral changes that accompany disease processes, such as heart failure and essential hypertension. The paradigm advanced in this volume is that heart disease is a multifaceted phenomenon involving the interplay of neurohumoral, cardiomyocyte and structural elements, each of which depends on the other. With our cumulative understanding of these interdependent processes, new avenues for time-appropriate, targeted methods of treating heart diseases can be developed.
Author: J. Andrew Armour
Publisher: Oxford University Press, USA
ISBN:
Category : Law
Languages : en
Pages : 464
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Book Description
New ideas about intrinsic and extrinsic cardiac intrathoracic neurons, the role of spinal cord and medullary and higher center neurons are presented. The final chapters focus on the role that autonomic neurons play in the maintenance of cardiac function in the conscious state as well as in two major clinical conditions, dysrythimias and heart failure.
Author: Anika Niambi Al-Shura
Publisher: Academic Press
ISBN: 012420077X
Category : Medical
Languages : en
Pages : 354
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Book Description
Combining the research and study of integrative Chinese and Western Medicine, Integrative Cardiovascular Chinese Medicine: A Prevention and Personalized Medicine Perspective presents a clear, structured base to guide clinical practice and encourage collaboration between Chinese medicine and Western medicine practitioners. This complete reference work thoroughly covers the pathophysiology of cardiology-related diseases, and compares, juxtaposes, and integrates Western and traditional Chinese medicine (TCM). Anika Niambi Al-Shura provides a realistic scope of cardiology treatment and the integration of Western and Chinese medicine, establishing a basis for standardization and a rationale for the inclusion of TCM in cardiology, and identifying and inspiring ideas for future research. - Integrates Western and Chinese medicine for a realistic scope of cardiology treatment - Establishes basis for standardization and rationale for the inclusion of traditional Chinese medicine in cardiology - "Clinical pearls" provide a guiding base of traditional Chinese medicine in clinical use - Offers a reference section that lists the latest in published studies - Presents easy access to the medicines and herbs used in both Chinese and Western medicine, including photos and information about the current patents
Author: C. J. Mathias
Publisher: Oxford University Press, USA
ISBN: 9780192628510
Category : Medical
Languages : en
Pages : 562
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Book Description
This fourth edition of Autonomic Failure (now available in paperback) covers the many recent advances made in our understanding of the autonomic nervous system. There are 20 new chapters and extensive revisions of all other contributions. Autonomic failure, fourth edition makes diagnosis increasingly precise by fully evaluating the underlying anatomical and functional deficits, thereby allowing more effective treatment. This new edition continues to provide practitioners from a variety of fields, including neurology, cardiology, geriatric medicine, diabetology, and internal medicine, with a rational guide to aid in the recognition and management of autonomic disorders. The book starts with an updated classification of autonomic disorders and a history of the autonomic nervous system. The first two sections of the book deal with the fundamental aspects of autonomic structure, function, and integration. There are new chapters dealing with neurobiology, nerve growth factors, genetic mutations, neural and hormonal control of the cerebral circulation, innervation of the lung, and pathophysiological mechanisms causing nausea and vomiting. Advances in the clinical management of autonomic disorders are critically dependent on the bridge made between the basic and applied sciences.
Author: David S. Goldstein
Publisher: Oxford University Press, USA
ISBN:
Category : Medical
Languages : en
Pages : 584
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Book Description
The starting point for understanding the roles of stress and catecholamines in cardiovascular disorders is a theory defining stress. This book presents a new homeostatic theory of stress and distress and uses it to explain how systems using the endogenous catecholamines - norepinephrine, epinephrine, and dopamine - and other effector systems maintain the internal environment during stress. The theory proposes coordinated activation of the body's several stress systems in primitively specific patterns during exposure to various stressors. Comparator homeostats interpret afferent information about specific physiological or chemical variables and regulate operations of the effector systems. Via a hierarchical mosaic of central nerve cell clusters, the brain constantly redefines homeostasis by resetting homeostats, especially during stress.
Author: Ambrose S. Kibos
Publisher: Springer Science & Business Media
ISBN: 1447153162
Category : Medical
Languages : en
Pages : 678
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Book Description
This book covers all the major aspects associated with pathophysiological development of cardiac arrhythmias (covering enhanced or suppressed automaticity, triggered activity, or re-entry), from basic concepts through disease association, limitations of current pharmacotherapy and implant therapies and on-going trials and analysis of new biomarkers based on current knowledge of cellular interaction and signalling. The book describes novel and state-of-the-art methods for differentiating between the major types of arrhythmia, structural abnormalities and current practice guidelines and determination of risk stratification associated with sudden cardiac death. A particular focus is on arrhythmias associated with atrial fibrillation and includes details of associations with cardiac disease, current detection, analysis and imaging and future perspectives.
Author: Nicholas Gall
Publisher: Springer Nature
ISBN: 3030541657
Category : Medical
Languages : en
Pages : 316
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Book Description
This book describes the varying clinical manifestations of postural tachycardia syndrome (PoTS) and provides a robust yet practical set of clinical tools for those managing patients suffering with this syndrome. Guidance is provided by a range of disciplines relevant to PoTS including general and specialist assessments, associated conditions, diagnostic considerations, therapy and service models. Postural Tachycardia Syndrome: A Concise and Practical Guide to Management and Associated Conditions presents the scientific background and practical information for the busy medical professional, illustrating key features with care-based materials to help them manage this condition, which can be a challenge for patients and clinicians alike.
Author: David H. Spodick
Publisher: CRC Press
ISBN: 9780824793166
Category : Medical
Languages : en
Pages : 496
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Book Description
Presents up-to-date coverage of the pericardium in health and medical and surgical disease, integrating recent advances in understanding normal and abnormal pericardial physiology and immunology, acute and chronic pericarditis, effusion and tamponade, and imaging methods for effusion and constriction. Incorporates clinical, hemodynamic, investigative, and experimental work conducted by leading interdisciplinary researchers--including never-before-published reports--on the normal and diseased pericardium.
Author: Loring B. Rowell
Publisher:
ISBN: 9780195073621
Category : Language Arts & Disciplines
Languages : en
Pages : 522
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Book Description
This new analysis of reflex and hormonal control of the human cardiovascular system developed from questions raised in Human Circulation: During Physical Stress (Rowell, 1986) and from recent findings. The goal is to help students, physiologists and clinicians understand the control of pressure, vascular volume, and blood flow by examining the cardiovascular system during orthostasis and exercise, two stresses that most affect these variables. A discussion of the passive physical properties of the vascular system provides a basis for explaining how vascular control is modified by mechanical, neural, and humoral factors. Interactive effects of the vasculature on cardiac performance are emphasized; they reveal the importance of autonomic control, supplemented by muscle pumping, in maintaining adequate ventricular filling pressure. The author's detailed analysis of how total oxygen consumption is restricted focuses on limitations in cardiac pumping ability, oxygen diffusion from lungs to blood and from blood to active muscle, oxidative metabolism and neural control of organ blood flow. An unsolved mystery is the nature of the signals that govern the cardiovascular responses to exercise. This is discussed in a new and critical synthesis of ideas and evidence concerning the "error signals" that are sensed and then corrected by activation of the autonomic nervous system during exercise.
Author: Roger Bannister
Publisher: Oxford University Press, USA
ISBN:
Category : Language Arts & Disciplines
Languages : en
Pages : 980
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Book Description
The third edition of this classic text, extensively revised, is now available in paperback, priced so that all interested physicians can have their own copy. The autonomic nervous system regulates, without conscious awareness, the function of the heart and all other bodily organs. Autonomic failure can cause a variety of seemingly strange symptoms, which may present to general physicians or a wide spectrum of specialists. This book shows how these symptoms can be studied scientifically in order to reach a precise diagnosis and instigate rational treatment.
