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Author: Aswin Sai Narain Seshasayee
Publisher: Cambridge University Press
ISBN: 1107079837
Category : Science
Languages : en
Pages : 227
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Book Description
This book presents the application of genomic tools to examine bacterial adaptation. The emphasis is on data analysis and interpretation.
Author: Aswin Sai Narain Seshasayee
Publisher: Cambridge University Press
ISBN: 1107079837
Category : Science
Languages : en
Pages : 227
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Book Description
This book presents the application of genomic tools to examine bacterial adaptation. The emphasis is on data analysis and interpretation.
Author: Lori A.S. Snyder
Publisher: Garland Science
ISBN: 1000039013
Category : Science
Languages : en
Pages : 416
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Book Description
Our understanding of bacterial genetics has progressed as the genomics field has advanced. Genetics and genomics complement and influence each other; they are inseparable. Under the novel insights from genetics and genomics, once-believed borders in biology start to fade: biological knowledge of the bacterial world is being viewed under a new light and concepts are being redefined. Species are difficult to delimit and relationships within and between groups of bacteria – the whole concept of a tree of life – is hotly debated when dealing with bacteria. The DNA within bacterial cells contains a variety of features and signals that influence the diversity of the microbial world. This text assumes readers have some knowledge of genetics and microbiology but acknowledges that it can be varied. Therefore, the book includes all of the information that readers need to know in order to understand the more advanced material in the book.
Author: Charles J. Dorman
Publisher: John Wiley & Sons
ISBN: 1119308798
Category : Science
Languages : en
Pages : 437
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Book Description
Presents an integrated view of the expression of bacterial genetic information, genome architecture and function, and bacterial physiology and pathogenesis This book blends information from the very latest research on bacterial chromosome and nucleoid architecture, whole-genome analysis, cell signaling, and gene expression control with well-known gene regulation paradigms from model organisms (including pathogens) to give readers a picture of how information flows from the environment to the gene, modulating its expression and influencing the competitive fitness of the microbe. Structure and Function of the Bacterial Genome explores the governance of the expression of the genes that make a bacterium what it is, and updates the basics of gene expression control with information about transcription promoter structure and function, the role of DNA as a regulatory factor (in addition to its role as a carrier of genetic information), small RNAs, RNAs that sense chemical signals, ribosomes and translation, posttranslational modification of proteins, and protein secretion. It looks at the forces driving the conservation and the evolution of the dynamic genome and offers chapters that cover DNA replication, DNA repair, plasmid biology, recombination, transposition, the roles of repetitive DNA sequences, horizontal gene transfer, the defense of the genome by CRISPR-Cas, restriction enzymes, Argonaute proteins and BREX systems. The book finishes with a chapter that gives an integrated overview of genome structure and function. Blends knowledge of gene regulatory mechanisms with a consideration of nucleoid structure and dynamics Offers a 'DNA-centric' approach to considering transcription control Views horizontal gene transfer from a gene regulation perspective Assesses the opportunities and limitations of designing synthetic microbes or rewiring existing ones Structure and Function of the Bacterial Genome is an ideal book for graduate and undergraduate students studying microbial cell biology, bacterial pathogenesis, gene regulation, and molecular microbiology. It will also appeal to principal investigators conducting research on these and related topics and researchers in synthetic biology and other arms of biotechnology.
Author: Francis Martin
Publisher: Springer Nature
ISBN: 1071628712
Category : Science
Languages : en
Pages : 370
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Book Description
This volume guides researchers on how to characterize, image rare, and hitherto unknown taxa and their interactions, to identify new functions and biomolecules and to understand how environmental changes condition the activity and the response of the organisms living with us and in our environment. Chapters cover different organism types (i.e., archaea, bacteria, fungi, protest, microfauna and microeukaryotes) and propose detailed protocols to produce high quality DNA, to analyse active microbial communities directly involved in complex interactions or processes through stable isotope probing, to identify and characterize of new functional genes, to image in situ interactions and to apply bioinformatics analysis tools to complex metagenomic or RNAseq sequence data. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Microbial Environmental Genomics (MEG): Methods and Protocols, Second Edition aims to serve as a primary research reference for researchers in microbiology working to in the expanding field of molecular ecology and environmental genomics.
Author: Jizhong Zhou
Publisher: John Wiley & Sons
ISBN: 9780471071907
Category : Science
Languages : en
Pages : 624
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Book Description
Microbial Functional Genomics offers a timely summary of the principles, approaches, and applications. It presents a comprehensive review of microbial functional genomics, covering microbial diversity, microbial genome sequencing, genomic technologies, genome-wide functional analysis, applied functional genomics, and future directions. An introduction will offer a definition of the field and an overview of the historical and comparative genomics aspects.
Author: Alessio Mengoni
Publisher:
ISBN: 9781493917204
Category : Bacterial genetics
Languages : en
Pages : 298
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Book Description
Author: David Wayne Ussery
Publisher: Springer Science & Business Media
ISBN: 1848002548
Category : Science
Languages : en
Pages : 272
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Book Description
Overview and Goals This book describes how to visualize and compare bacterial genomes. Sequencing technologies are becoming so inexpensive that soon going for a cup of coffee will be more expensive than sequencing a bacterial genome. Thus, there is a very real and pressing need for high-throughput computational methods to compare hundreds and thousands of bacterial genomes. It is a long road from molecular biology to systems biology, and in a sense this text can be thought of as a path bridging these ? elds. The goal of this book is to p- vide a coherent set of tools and a methodological framework for starting with raw DNA sequences and producing fully annotated genome sequences, and then using these to build up and test models about groups of interacting organisms within an environment or ecological niche. Organization and Features The text is divided into four main parts: Introduction, Comparative Genomics, Transcriptomics and Proteomics, and ? nally Microbial Communities. The ? rst ? ve chapters are introductions of various sorts. Each of these chapters represents an introduction to a speci? c scienti? c ? eld, to bring all readers up to the same basic level before proceeding on to the methods of comparing genomes. First, a brief overview of molecular biology and of the concept of sequences as biological inf- mation are given.
Author: Surajit Das
Publisher: Academic Press
ISBN: 0128148500
Category : Science
Languages : en
Pages : 715
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Book Description
Microbial Diversity in the Genomic Era presents insights on the techniques used for microbial taxonomy and phylogeny, along with their applications and respective pros and cons. Though many advanced techniques for the identification of any unknown bacterium are available in the genomics era, a far fewer number of the total microbial species have been discovered and identified to date. The assessment of microbial taxonomy and biosystematics techniques discovered and practiced in the current genomics era with suitable recommendations is the prime focus of this book. - Discusses the techniques used for microbial taxonomy and phylogeny with their applications and respective pros and cons - Reviews the evolving field of bacterial typing and the genomic technologies that enable comparative analysis of multiple genomes and the metagenomes of complex microbial environments - Provides a uniform, standard methodology for species designation
Author: Ying Xu
Publisher: World Scientific
ISBN: 1860949827
Category : Medical
Languages : en
Pages : 494
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Book Description
Over 500 prokaryotic genomes have been sequenced to date, and thousands more have been planned for the next few years. While these genomic sequence data provide unprecedented opportunities for biologists to study the world of prokaryotes, they also raise extremely challenging issues such as how to decode the rich information encoded in these genomes. This comprehensive volume includes a collection of cohesively written chapters on prokaryotic genomes, their organization and evolution, the information they encode, and the computational approaches needed to derive such information. A comparative view of bacterial and archaeal genomes, and how information is encoded differently in them, is also presented. Combining theoretical discussions and computational techniques, the book serves as a valuable introductory textbook for graduate-level microbial genomics and informatics courses.
Author: Nancy Trun
Publisher: John Wiley & Sons
ISBN: 1444311557
Category : Science
Languages : en
Pages : 304
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Book Description
Fundamental Bacterial Genetics presents a conciseintroduction to microbial genetics. The text focuses on onebacterial species, Escherichia coli, but draws examples fromother microbial systems at appropriate points to support thefundamental concepts of molecular genetics. A solid balance ofconcepts, techniques and applications makes this book anaccessible, essential introduction to the theory and practice offundamental microbial genetics. FYI boxes - feature key experiments that lead to what we nowknow, biographies of key scientists, comparisons with other speciesand more. Study questions - at the end of each chapter, review and teststudents' knowledge of key chapter concepts. Key references - included both at chapter end and in a fullreference list at the end of the book. Full Chapter on Genomics, Bioinformatics and Proteomics -includes coverage of functional genomics and microarrays. Dedicated website – animations, study resources, webresearch questions and illustrations downloadable for powerpointfiles provide students and instructors with an enhanced,interactive experience.
