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Author: D.B. Clewell
Publisher: Springer Science & Business Media
ISBN: 147579357X
Category : Medical
Languages : en
Pages : 421
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Book Description
Bacterial plasmids originating in a wide range of genera are being studied from a variety of perspectives in hundreds of laboratories around the globe. These elements are well known for carrying "special" genes that confer important survival properties, frequently neces sary under atypical conditions. Classic examples of plasmid-borne genes are those provid ing bacterial resistance to toxic substances such as antibiotics, metal ions, and bacte riophage. Often included are those determining bacteriocins, which may give the bacterium an advantage in a highly competitive environment. Genes offering metabolic alternatives to the cell under nutritionally stressed conditions are also commonly found on plasmids, as are determinants important to colonization and pathogenesis. It is likely that in many, if not most, cases plasmids and their passenger determinants represent DNA acquired recently by their bacterial hosts, and it is the characteristic mobility of these elements that enables their efficient establishment in new bacterial cells by the process known as conjugation. Whereas many plasmids are fully capable of promoting their own conjugal transfer, others move only with help from coresident elements. The ability of a plasmid to establish itself in a variety of different species is com mon, and recent studies have shown that transfer can in some cases occur from bacterial cells to eukaryotes such as yeast.
Author: D.B. Clewell
Publisher: Springer Science & Business Media
ISBN: 147579357X
Category : Medical
Languages : en
Pages : 421
Get Book Here
Book Description
Bacterial plasmids originating in a wide range of genera are being studied from a variety of perspectives in hundreds of laboratories around the globe. These elements are well known for carrying "special" genes that confer important survival properties, frequently neces sary under atypical conditions. Classic examples of plasmid-borne genes are those provid ing bacterial resistance to toxic substances such as antibiotics, metal ions, and bacte riophage. Often included are those determining bacteriocins, which may give the bacterium an advantage in a highly competitive environment. Genes offering metabolic alternatives to the cell under nutritionally stressed conditions are also commonly found on plasmids, as are determinants important to colonization and pathogenesis. It is likely that in many, if not most, cases plasmids and their passenger determinants represent DNA acquired recently by their bacterial hosts, and it is the characteristic mobility of these elements that enables their efficient establishment in new bacterial cells by the process known as conjugation. Whereas many plasmids are fully capable of promoting their own conjugal transfer, others move only with help from coresident elements. The ability of a plasmid to establish itself in a variety of different species is com mon, and recent studies have shown that transfer can in some cases occur from bacterial cells to eukaryotes such as yeast.
Author: D.B. Clewell
Publisher: Springer Science & Business Media
ISBN:
Category : Medical
Languages : en
Pages : 440
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Book Description
This timely volume reviews the molecular mechanisms and regulation aspects of conjugation in a variety of bacterial systems. An international group of contributors examine the movement of plasmids and conjugative transposons across species and kingdom barriers, and discuss the significance of the transfer phenomenon from clinical, environmental, and industrial perspectives.
Author: Gregory Phillips
Publisher: Washington, DC : ASM Press
ISBN:
Category : Plasmids
Languages : en
Pages : 648
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Book Description
This book opens with an essay on the historical perspective of the study of plasmids, reviewing important events and discoveries that have propelled the field forward. The remaining chapters are divided into six sections, detailing basic biological processes such as replication and inheritance functions, specific plasmid systems, plasmid evolution, and use of plasmids as genetic tools. Chapters include use of genomic approaches for the study of plasmid biology, and a review of plasmids from bacteria, archaea, and eukaryotes is presented. In-depth treatment is given to diversity of plasmid systems in the natural environment, and the development of plasmid use in the laboratory is also covered.
Author: Peter Mullany
Publisher: Cambridge University Press
ISBN: 9780521821575
Category : Medical
Languages : en
Pages : 452
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Book Description
"This book provides an in-depth analysis of the mechanisms and biological consequences of genome rearrangements in bacteria. Each chapter examines the mechanisms involved in genome rearrangements and the direct biological consequences of these events. Because genome rearrangements are so important in evolution, at least one of the chapters views the phenomenon from an evolutionary angle. This book provides the reader with a holistic view of genome rearrangements (i.e., studies on both the biological consequences of genome rearrangement and the mechanisms underlying these processes are presented)." "The book is written by leading research workers in the field and is aimed at final-year undergraduates, postgraduate and postdoctoral workers, and established biologists."--BOOK JACKET.
Author: Donald R. Helinski
Publisher: Springer Science & Business Media
ISBN: 1461324475
Category : Medical
Languages : en
Pages : 982
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Book Description
Author: Christopher M. Thomas
Publisher: CRC Press
ISBN: 0203304330
Category : Science
Languages : en
Pages : 459
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Book Description
Bacteria are the most ubiquitous of all organisms. Responsible for a number of diseases and for many of the chemical cycles on which life depends, they are genetically adaptable. Vital to this adaptability is the existence of autonomous genetic elements-plasmids-which promote genetic exchange and recombination. The genes carried by any particular plasmid may be found in only a few individuals of any species but can also be shared with other species and thus constitute a horizontal gene pool. This book explains the various contributions that plasmids make to this pool: the replication, stable inheritance and transfer modules, the phenotypic markers they carry, the way they evolve, the ways they contribute to their host population and the approaches that we use to study and classify them. It also looks at what we know about their activity in natural communities and the way that they interact with other mobile elements to promote bacterial evolution.
Author: Maclyn McCarty
Publisher: W. W. Norton & Company
ISBN: 9780393304503
Category : Philosophy
Languages : en
Pages : 258
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Book Description
Forty years ago, three medical researchers--Oswald Avery, Colin MacLeod, and Maclyn McCarty--made the discovery that DNA is the genetic material. With this finding was born the modern era of molecular biology and genetics.
Author: Edward A. Birge
Publisher: Springer Science & Business Media
ISBN: 1475719957
Category : Science
Languages : en
Pages : 432
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Book Description
Bacterial genetics has become one of the cornerstones of basic and applied microbiology and has contributed key knowledge for many of the fundamental advances of modern biology. The second edition of this comprehensive yet concise text, first published in 1981, has been thoroughly updated and redesigned to account for new developments in this rapidly expanding field. All of the major topics in modern bacterial and bacteriophage genetics are presented, among them mutations and mutagenesis, genetics of T4 bacteriophage and other intemperate and temperate phages, transduction, transformation, conjugation and plasmids, recombination and repair, probability laws for prokaryote cultures, as well as applied bacterial genetics.
Author: Richard Goering
Publisher: Elsevier Health Sciences
ISBN: 0702072028
Category : Medical
Languages : en
Pages : 662
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Book Description
Learn all the microbiology and basic immunology concepts you need to know for your courses and exams. Now fully revised and updated, Mims' clinically relevant, systems-based approach and abundant colour illustrations make this complex subject easy to understand and remember. - Learn about infections in the context of major body systems and understand why these are environments in which microbes can establish themselves, flourish, and give rise to pathologic changes. This systems-based approach to microbiology employs integrated and case-based teaching that places the 'bug parade' into a clinical context. - Effectively review for problem-based courses with the help of chapter introductions and 'Lessons in Microbiology' text boxes that highlight the clinical relevance of the material, offer easy access to key concepts, and provide valuable review tools. - Approach microbiology by body system or by pathogen through the accompanying electronic 'Pathogen Parade' – a quickly searchable, cross-referenced glossary of viruses, bacteria and fungi - A new electronic 'Vaccine Parade' offers quick-reference coverage of the most commonly used vaccines in current clinical practice - Deepen your understanding of epidemiology and the important role it plays in providing evidence-based identification of key risk factors for disease and targets for preventative medicine. - Grasp and retain vital concepts easily, with a user-friendly colour coded format, succinct text, key concept boxes, and dynamic illustrations. - New and enhanced information reflects the growing importance of the human microbiota and latest molecular approaches - Access the complete contents on the go via the accompanying interactive eBook, with a range of bonus materials to enhance learning and retention – includes self-assessment materials and clinical cases to check your understanding and aid exam preparation.
Author: Stanley Maloy
Publisher: Academic Press
ISBN: 0080961568
Category : Science
Languages : en
Pages : 4360
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Book Description
The explosion of the field of genetics over the last decade, with the new technologies that have stimulated research, suggests that a new sort of reference work is needed to keep pace with such a fast-moving and interdisciplinary field. Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set, builds on the foundation of the first edition by addressing many of the key subfields of genetics that were just in their infancy when the first edition was published. The currency and accessibility of this foundational content will be unrivalled, making this work useful for scientists and non-scientists alike. Featuring relatively short entries on genetics topics written by experts in that topic, Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set provides an effective way to quickly learn about any aspect of genetics, from Abortive Transduction to Zygotes. Adding to its utility, the work provides short entries that briefly define key terms, and a guide to additional reading and relevant websites for further study. Many of the entries include figures to explain difficult concepts. Key terms in related areas such as biochemistry, cell, and molecular biology are also included, and there are entries that describe historical figures in genetics, providing insights into their careers and discoveries. This 7-volume set represents a 25% expansion from the first edition, with over 1600 articles encompassing this burgeoning field Thoroughly up-to-date, with many new topics and subfields covered that were in their infancy or not inexistence at the time of the first edition. Timely coverage of emergent areas such as epigenetics, personalized genomic medicine, pharmacogenetics, and genetic enhancement technologies Interdisciplinary and global in its outlook, as befits the field of genetics Brief articles, written by experts in the field, which not only discuss, define, and explain key elements of the field, but also provide definition of key terms, suggestions for further reading, and biographical sketches of the key people in the history of genetics
