Approaches to Drug Sample Differentiation

Approaches to Drug Sample Differentiation PDF Author: Juei H. Liu
Publisher:
ISBN:
Category : Chemistry, Forensic
Languages : en
Pages : 92

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Book Description

Approaches to Drug Sample Differentiation

Approaches to Drug Sample Differentiation PDF Author: Juei H. Liu
Publisher:
ISBN:
Category : Chemistry, Forensic
Languages : en
Pages : 92

Get Book Here

Book Description


Approaches to Drug Sample Differentiation. I

Approaches to Drug Sample Differentiation. I PDF Author: JH. Liu
Publisher:
ISBN:
Category : Analytical chemistry
Languages : en
Pages : 5

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Book Description
Differentiation of drug samples can be based on at least three different approaches. Conventional methods use qualitative and quantitative determinations of impurities or minor components. Samples may also be differentiated by variations in a naturally occurring isotope such as carbon-13, whose content varies because of differences of carbon fixation conditions for cultivated plant drugs or from differences in reaction conditions for synthesized drugs. A third approach involves the determination of various diastereoisomeric or enantiomeric compositions or both. This last approach also serves an essential purpose in cases where one isomer is under regulation while other(s) may not be. Representative works are reviewed.

Approaches to Drug Sample Differentiation. II

Approaches to Drug Sample Differentiation. II PDF Author: JH. Liu
Publisher:
ISBN:
Category : Amphetamine
Languages : en
Pages : 8

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Book Description
Synthesized tris[d,d-dicampholylmethanato]europium(III), Eu(dcm)3, and three other commercially available chiral lanthanide shift reagents are used to resolve the nuclear magnetic resonance (NMR) spectra of the enantiomeric N-CH3 and C-CH3 protons in d- and l-methamphetamine. The chemical shift difference between the corresponding enantiomeric protons induced by these four shift reagents are compared and evaluated in their prospective use for enantiomeric identification and determination. It is concluded that while the chemical shift difference between the two enantiomerie C-CH3 protons induced by Eu(dcm)3 is most suitable for qualitative identification of these enantiomers, the NMR spectra of the N-CH3 protons are best resolved by Eu(dcm)3 and most suitable for quantitative determinations.

The Forensic Laboratory Handbook

The Forensic Laboratory Handbook PDF Author: Ashraf Mozayani
Publisher: Springer Science & Business Media
ISBN: 159259946X
Category : Medical
Languages : en
Pages : 307

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Book Description
A comprehensive and easy-to-read introduction to the work of the modern forensic laboratory. The authors explain in simple language the capabilities and limitations of modern forensic laboratory procedures, techniques, analyses, and interpretations. Here, the interested reader will find an understandable and fascinating introduction to the complex worlds of forensic serology DNA, chemistry, crime reconstruction, digital evidence, explosives, arson, fingerprints, firearms, tool marks, odontology, and pathology. Additional chapters address the problems of assuring quality and seeking trace evidence in the forensic laboratory.

Approaches to Drug Sample Differentiation. III

Approaches to Drug Sample Differentiation. III PDF Author: JH. Liu
Publisher:
ISBN:
Category : Amphetamine
Languages : en
Pages : 10

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Book Description
A gas chromatograph/mass spectrometer (GC/MS) system equipped with a chiral and an achiral capillary column is used to analyze control methamphetamine, an illicit methamphetamine preparation ("White Cross"), and a simulated illicit methamphetamine synthesis product. Samples are derivatized with N-trifluoroacetyl-l-prolyl chloride (I-TPC) before the GC/MS analysis. The results obtained lead to the conclusion that the resolution on an achiral column is adequate for the determination of methamphetamine enantiomers and impurities, providing the enantiomeric impurity of the l-TPC is known. Four new possible by-products of methamphetamine preparations were identified in the simulated illicit methamphetamine synthesis product.

Novel Approaches to Improve Detection, Differentiation and Treatment in Mood Disorders

Novel Approaches to Improve Detection, Differentiation and Treatment in Mood Disorders PDF Author: Danilo Arnone
Publisher: Frontiers Media SA
ISBN: 2889747670
Category : Medical
Languages : en
Pages : 120

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Book Description


Forensic Science Handbook

Forensic Science Handbook PDF Author: Richard Saferstein
Publisher: Prentice Hall
ISBN:
Category : Law
Languages : en
Pages : 488

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Book Description
Collection of articles written by experts in the forensic science area. Volume III has an emphasis on DNA research. Book is intended for the professional/graduate audience.

Excerpta Medica

Excerpta Medica PDF Author:
Publisher:
ISBN:
Category : Drug abuse
Languages : en
Pages : 768

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Book Description


Quantitation and Mass Spectrometric Data of Drugs and Isotopically Labeled Analogs

Quantitation and Mass Spectrometric Data of Drugs and Isotopically Labeled Analogs PDF Author: Ray H. Liu
Publisher: CRC Press
ISBN: 142009498X
Category : Law
Languages : en
Pages : 506

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Book Description
The analysis of drugs and their metabolites in biological media are now expected to routinely achieve 20% accuracy in the ng/mL concentration level. Therefore, the availability and the selection of quality ion-pairs designating the analytes and their isotopically labeled analogs (ILAs) are important considerations in achieving the accuracy of qua

How To Succeed in Differentiation: The Finnish Approach

How To Succeed in Differentiation: The Finnish Approach PDF Author: Anssi Roiha
Publisher: John Catt
ISBN: 1398382906
Category : Education
Languages : en
Pages : 281

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Book Description
Differentiation is an approach to education in which every student's individuality and special needs are taken into account. Practical and accessible, HOW TO SUCCEED IN DIFFERENTIATION reveals the approach taken in the high-achieving Finnish education system, where the national curriculum obligates all teachers to differentiate their teaching from the get-go. The book is divided into four parts. Part I explains the background of Finnish education and differentiation in the Finnish context. Part II investigates the theoretical basis for differentiation and strives to offer new perspectives for the most common challenges of differentiation. In addition, Part II introduces the reader to the imaginary example students, whose problems are attempted to be solved later in the book. In Part III, differentiation is approached through the five-dimensional model of differentiation, which the authors have created and which, in their opinion, covers the most central areas of teaching, in which differentiation should be acknowledged. In Part IV, differentiation is exemplified in language and literature, mathematics and foreign languages.