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Author: Paul W. Strike
Publisher: Butterworth-Heinemann
ISBN:
Category : Medical
Languages : en
Pages : 558
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Book Description
Author: Paul W. Strike
Publisher: Butterworth-Heinemann
ISBN:
Category : Medical
Languages : en
Pages : 558
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Book Description
Author: Brian Everitt
Publisher: Springer Science & Business Media
ISBN: 1441996508
Category : Mathematics
Languages : en
Pages : 284
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Book Description
The majority of data sets collected by researchers in all disciplines are multivariate, meaning that several measurements, observations, or recordings are taken on each of the units in the data set. These units might be human subjects, archaeological artifacts, countries, or a vast variety of other things. In a few cases, it may be sensible to isolate each variable and study it separately, but in most instances all the variables need to be examined simultaneously in order to fully grasp the structure and key features of the data. For this purpose, one or another method of multivariate analysis might be helpful, and it is with such methods that this book is largely concerned. Multivariate analysis includes methods both for describing and exploring such data and for making formal inferences about them. The aim of all the techniques is, in general sense, to display or extract the signal in the data in the presence of noise and to find out what the data show us in the midst of their apparent chaos. An Introduction to Applied Multivariate Analysis with R explores the correct application of these methods so as to extract as much information as possible from the data at hand, particularly as some type of graphical representation, via the R software. Throughout the book, the authors give many examples of R code used to apply the multivariate techniques to multivariate data.
Author: Alfred Bartolucci
Publisher: John Wiley & Sons
ISBN: 1118736869
Category : Mathematics
Languages : en
Pages : 259
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Book Description
Introduction to Statistical Analysis of Laboratory Data presents a detailed discussion of important statistical concepts and methods of data presentation and analysis Provides detailed discussions on statistical applications including a comprehensive package of statistical tools that are specific to the laboratory experiment process Introduces terminology used in many applications such as the interpretation of assay design and validation as well as “fit for purpose” procedures including real world examples Includes a rigorous review of statistical quality control procedures in laboratory methodologies and influences on capabilities Presents methodologies used in the areas such as method comparison procedures, limit and bias detection, outlier analysis and detecting sources of variation Analysis of robustness and ruggedness including multivariate influences on response are introduced to account for controllable/uncontrollable laboratory conditions
Author: University of California, San Francisco
Publisher:
ISBN:
Category :
Languages : en
Pages : 1000
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Book Description
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309171148
Category : Medical
Languages : en
Pages : 221
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Book Description
Clinical trials are used to elucidate the most appropriate preventive, diagnostic, or treatment options for individuals with a given medical condition. Perhaps the most essential feature of a clinical trial is that it aims to use results based on a limited sample of research participants to see if the intervention is safe and effective or if it is comparable to a comparison treatment. Sample size is a crucial component of any clinical trial. A trial with a small number of research participants is more prone to variability and carries a considerable risk of failing to demonstrate the effectiveness of a given intervention when one really is present. This may occur in phase I (safety and pharmacologic profiles), II (pilot efficacy evaluation), and III (extensive assessment of safety and efficacy) trials. Although phase I and II studies may have smaller sample sizes, they usually have adequate statistical power, which is the committee's definition of a "large" trial. Sometimes a trial with eight participants may have adequate statistical power, statistical power being the probability of rejecting the null hypothesis when the hypothesis is false. Small Clinical Trials assesses the current methodologies and the appropriate situations for the conduct of clinical trials with small sample sizes. This report assesses the published literature on various strategies such as (1) meta-analysis to combine disparate information from several studies including Bayesian techniques as in the confidence profile method and (2) other alternatives such as assessing therapeutic results in a single treated population (e.g., astronauts) by sequentially measuring whether the intervention is falling above or below a preestablished probability outcome range and meeting predesigned specifications as opposed to incremental improvement.
Author: Amir Momeni
Publisher: Springer
ISBN: 3319605437
Category : Medical
Languages : en
Pages : 322
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Book Description
This text provides a comprehensive and practical review of the main statistical methods in pathology and laboratory medicine. It introduces statistical concepts used in pathology and laboratory medicine. The information provided is relevant to pathologists both for their day to day clinical practice as well as in their research and scholarly activities. The text will begins by explaining the fundamentals concepts in statistics. In the later sections, these fundamental concepts are expanded and unique applications of statistical methods in pathology and laboratory medicine practice are introduced. Other sections of the text explain research methodology in pathology covering a broad range of topics from study design to analysis of data. Finally, data-heavy novel concepts that are emerging in pathology and pathology research are presented such as molecular pathology and pathology informatics. Introduction to Statistical Methods in Pathology will be of great value for pathologists, pathology residents, basic and translational researchers, laboratory managers and medical students.
Author: Joachim Hartung
Publisher: John Wiley & Sons
ISBN: 1118210964
Category : Medical
Languages : en
Pages : 215
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Book Description
An accessible introduction to performing meta-analysis across various areas of research The practice of meta-analysis allows researchers to obtain findings from various studies and compile them to verify and form one overall conclusion. Statistical Meta-Analysis with Applications presents the necessary statistical methodologies that allow readers to tackle the four main stages of meta-analysis: problem formulation, data collection, data evaluation, and data analysis and interpretation. Combining the authors' expertise on the topic with a wealth of up-to-date information, this book successfully introduces the essential statistical practices for making thorough and accurate discoveries across a wide array of diverse fields, such as business, public health, biostatistics, and environmental studies. Two main types of statistical analysis serve as the foundation of the methods and techniques: combining tests of effect size and combining estimates of effect size. Additional topics covered include: Meta-analysis regression procedures Multiple-endpoint and multiple-treatment studies The Bayesian approach to meta-analysis Publication bias Vote counting procedures Methods for combining individual tests and combining individual estimates Using meta-analysis to analyze binary and ordinal categorical data Numerous worked-out examples in each chapter provide the reader with a step-by-step understanding of the presented methods. All exercises can be computed using the R and SAS software packages, which are both available via the book's related Web site. Extensive references are also included, outlining additional sources for further study. Requiring only a working knowledge of statistics, Statistical Meta-Analysis with Applications is a valuable supplement for courses in biostatistics, business, public health, and social research at the upper-undergraduate and graduate levels. It is also an excellent reference for applied statisticians working in industry, academia, and government.
Author: Alan J. Izenman
Publisher: Springer Science & Business Media
ISBN: 0387781897
Category : Mathematics
Languages : en
Pages : 757
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Book Description
This is the first book on multivariate analysis to look at large data sets which describes the state of the art in analyzing such data. Material such as database management systems is included that has never appeared in statistics books before.
Author:
Publisher: ScholarlyEditions
ISBN: 1481607286
Category : Medical
Languages : en
Pages : 92
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Book Description
Macrophage-Activating Factors—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Macrophage-Activating Factors in a concise format. The editors have built Macrophage-Activating Factors—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Macrophage-Activating Factors in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Macrophage-Activating Factors—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author: Jane C. Miller
Publisher: Ellis Horwood Limited
ISBN: 9780138454210
Category : Chemistry, Analytic
Languages : en
Pages : 227
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Book Description
