Molecular Biology of the Cell

Molecular Biology of the Cell PDF Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0

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Book Description

Molecular Biology of the Cell

Molecular Biology of the Cell PDF Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0

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Book Description


Apoptosis and Cancer

Apoptosis and Cancer PDF Author: Seamus J. Martin
Publisher: R G Landes Company
ISBN: 9781570594526
Category : Medical
Languages : en
Pages : 265

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Book Description


Apoptosis

Apoptosis PDF Author: C. S. Potten
Publisher: Cambridge University Press
ISBN: 9780521626798
Category : Medical
Languages : en
Pages : 240

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Book Description
The concept of programmed cell death, or apoptosis, has exploded into a major scientific field of interest for cell biologists, oncologists, and many other biomedical researchers. Apoptosis occurs throughout the lifetime of most multicellular organisms. During development, for example, the selective death of cells is vital to remove tissue between the digits to produce fingers and toes. Apoptosis is also necessary to destroy cells that represent a threat to the integrity of the organism, for example cells infected by a virus. In many cancers the genes regulating apoptosis are defective, producing immortal, continuously proliferating cells. This book discusses the philosophical and technical difficulties in defining the moment of death for a cell, as well as the biological implications and significance of programmed cell death. Recent developments in the genetic control and interacting gene networks associated with apoptosis are presented. The book is written for advanced undergraduate and postgraduate students, and is highly illustrated to aid understanding.

Human Cytomegalovirus

Human Cytomegalovirus PDF Author: Thomas E. Shenk
Publisher: Springer Science & Business Media
ISBN: 3540773495
Category : Medical
Languages : en
Pages : 477

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Book Description
This volume has gathered some of the experts in the field to review aspects of our understanding of CMV and to offer perspectives of the current problems associated with CMV. The editors and authors hope that the chapters will lead to a better understanding of the virus that will assist in the development of new and unique antivirals, a protective vaccine, and a full understanding of CMV's involvement in human disease.

Apoptosis

Apoptosis PDF Author: Michael D. Jacobson
Publisher: Frontiers in Molecular Biology
ISBN: 9780199638499
Category : Medical
Languages : en
Pages : 366

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Book Description
The number of cells within the human body is very tightly regulated: too many and we can develop cancer, too few and we may lose cells that we cannot replace. The number of cells is controlled by several different mechanisms in different tissues, but all are triggered to commit suicide should too many be in one place at one time, or become damaged. This book examines how this process of cell suicide (apoptosis) is regulated, and how our understanding of this process may lead to novel treatments for a wide variety of human diseases.

Cell Surface GRP78, a New Paradigm in Signal Transduction Biology

Cell Surface GRP78, a New Paradigm in Signal Transduction Biology PDF Author: Salvatore V. Pizzo
Publisher: Academic Press
ISBN: 0128123524
Category : Science
Languages : en
Pages : 146

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Book Description
Cell Surface GRP78, a New Paradigm in Signal Transduction Biology presents a new paradigm that has emerged in the past decade with the discovery that various intracellular proteins may acquire new functions as cell surface receptors. Two very prominent examples are ATP synthase and GRP78. While the role of cell surface ATP synthase has been reviewed in various books, this book directs its attention to the story of cell surface GRP78. - Edited by the researcher who identified cell surface expression of the molecular chaperone GRP78 as a major factor in prostate cancer and other malignancies - Presents an in-depth treatment of the biological underpinnings of GRP78 and its connection to disease - Provides four-color illustrations that facilitate the narrative

Cell Death

Cell Death PDF Author: Douglas R. Green
Publisher:
ISBN: 9781621822141
Category : Science
Languages : en
Pages : 0

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Book Description
A million cells in our bodies die every second--they commit suicide by activating a process called apoptosis or other forms of programmed cell death. These mechanisms are essential for survival of the body as a whole and play critical roles in various developmental processes, the immune system, and cancer. In this second edition of Douglas Green's essential book on cell death, Green retains the bottom-up approach of the first edition, starting with the enzymes that carry out the execution (caspases) and their cellular targets before examining the machinery that connects them to signals that cause cell death. He also describes the roles of cell death in development, neuronal selection, and the development of self-tolerance in the immune system, as well as how the body uses cell death to defend against cancer. The new edition is fully updated to cover the many recent advances in our understanding of the death machinery and signals that control cell death. These include the mechanisms regulating necroptosis, mitophagy, and newly identified processes, such as ferroptosis. The book will thus be of great interest to researchers actively working in the field, as well as biologists and undergraduates encountering the topic for the first time.

Apoptosis Genes

Apoptosis Genes PDF Author: James W. Wilson
Publisher: Springer Science & Business Media
ISBN: 9780412838606
Category : Medical
Languages : en
Pages : 328

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Book Description
This useful work presents a current overview of key genes involved in the control of apoptosis research together with thoughts on future prospects and clinical applications. While there are several books written on apoptosis, this one deals specifically with its regulation.

Perspectives on Mammalian Cell Death

Perspectives on Mammalian Cell Death PDF Author: C. S. Potten
Publisher: Oxford University Press, USA
ISBN:
Category : Nature
Languages : en
Pages : 394

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Book Description
This volume covers the wide range of approaches to and definitions of cell death as explored by scientists in different disciplines. There is no single definition of cell death that can be accepted and used by all biologists, yet it is clear that understanding how and why cells die is crucial to understanding many biological and pathological processes. The thirteen chapters, written by scientists involved in various disciplines, bring together the experimental approaches and most up-to-date concepts important to different biological disciplines, providing an insight into the common ground and fundamental principles.

Sunlight, Vitamin D and Skin Cancer

Sunlight, Vitamin D and Skin Cancer PDF Author: Jörg Reichrath
Publisher: Springer Nature
ISBN: 3030462277
Category : Medical
Languages : en
Pages : 422

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Book Description
The third edition is a comprehensive and updated overview of positive and negative effects of UV-exposure, with a focus on Vitamin D and skin cancer. Researchers, oncologists,and students will be provided with the most significant and timely information related to topics such as the epidemiology of skin cancer, the immune system and skin cancer, ultraviolet damage, DNA repair and Vitamin D in Nonmelanoma skin cancer and malignant melanoma. There have been a number of new, scientific findings in this fast moving field that necessitated a thoroughly updated and revised edition including new Vitamin D metabolites and skin cancer, new findings on the beneficial effects of UV and solar UV and skin cancer, adverse effects of sun protection and sunscreens, sun exposure and mortality, and more. The book will summarize essential, up-to-date information for every clinician or scientist interested in how to balance the positive and negative effects of UV‐exposure to minimize the risks of developing vitamin D deficiency and skin cancer.