Author: Brian Henderson
Publisher: John Wiley & Sons
ISBN: 1118951123
Category : Science
Languages : en
Pages : 497
Get Book Here
Book Description
Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections is a complete examination of the ways in which proteins with more than one unique biological action are able to serve as virulence factors in different bacteria. The book explores the pathogenicity of bacterial moonlighting proteins, demonstrating the plasticity of protein evolution as it relates to protein function and to bacterial communication. Highlighting the latest discoveries in the field, it details the approximately 70 known bacterial proteins with a moonlighting function related to a virulence phenomenon. Chapters describe the ways in which each moonlighting protein can function as such for a variety of bacterial pathogens and how individual bacteria can use more than one moonlighting protein as a virulence factor. The cutting-edge research contained here offers important insights into many topics, from bacterial colonization, virulence, and antibiotic resistance, to protein structure and the therapeutic potential of moonlighting proteins. Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections will be of interest to researchers and graduate students in microbiology (specifically bacteriology), immunology, cell and molecular biology, biochemistry, pathology, and protein science.
Author: Mukesh C Limbachiya
Publisher: CRC Press
ISBN: 0203883446
Category : Technology & Engineering
Languages : en
Pages : 596
Get Book Here
Book Description
The concrete industry has embraced innovation and ensured high levels of long-term performance and sustainability through creative applications in design and construction. As a construction material, the versatility of concrete and its intrinsic benefits mean it is still well placed to meet challenges of the construction industry. Indeed, concrete
Author: G Singh Chhatwal
Publisher: Springer Science & Business Media
ISBN: 3642363407
Category : Medical
Languages : en
Pages : 258
Get Book Here
Book Description
Streptococci are Gram-positive bacteria that cause a wide spectrum of diseases, such as pharyngitis, necrotizing fasciitis and streptococcal toxic shock syndrome, as well as rheumatic fever and rheumatic heart disease as sequelae. Antibiotics alone have not been able to control the disease and in spite of many efforts an effective vaccine is not yet available. A prerequisite for novel and successful strategies for combating these bacteria is a complete understanding of the highly complex pathogenic mechanisms involved, which are analyzed in this volume. In ten chapters, prominent authors cover various aspects including streptococcal diseases and global burden, epidemiology, adaptation and transmission, and molecular mechanisms of different diseases, as well as sequelae, vaccine development and clinical management. This book will serve as a valuable reference work for scientists, students, clinicians and public health workers and provide new approaches to meeting the challenge of streptococcal diseases.
Author: Dharumadurai Dhanasekaran
Publisher: BoD – Books on Demand
ISBN: 9535124358
Category : Medical
Languages : en
Pages : 526
Get Book Here
Book Description
In the book Microbial Biofilms: Importance and applications, eminent scientists provide an up-to-date review of the present and future trends on biofilm-related research. This book is divided with four subdivisions as biofilm fundamentals, applications, health aspects, and their control. Moreover, this book also provides a comprehensive account on microbial interactions in biofilms, pyocyanin, and extracellular DNA in facilitating Pseudomonas aeruginosa biofilm formation, atomic force microscopic studies of biofilms, and biofilms in beverage industry. The book comprises a total of 21 chapters from valued contributions from world leading experts in Australia, Bulgaria, Canada, China, Serbia, Germany, Italy, Japan, the United Kingdom, the Kingdom of Saudi Arabia, Republic of Korea, Mexico, Poland, Portugal, and Turkey. This book may be used as a text or reference for everyone interested in biofilms and their applications. It is also highly recommended for environmental microbiologists, soil scientists, medical microbiologists, bioremediation experts, and microbiologists working in biocorrosion, biofouling, biodegradation, water microbiology, quorum sensing, and many other related areas. Scientists in academia, research laboratories, and industry will also find it of interest.
Author: Moid Siddiqui
Publisher: SAGE
ISBN: 9780761932970
Category : Business & Economics
Languages : en
Pages : 312
Get Book Here
Book Description
This delightful and thought-provoking book is aimed at the new manager who seeks to blend materialism with spirituality. Encapsulating the wisdom of the finest ancient schools of thought, Moid Siddiqui correlates them to key elements that define modern management. Drawing from time-tested concepts in Chinese, Japanese, Greek, Indian, Islamic and Christian philosophy, he discusses: - Wisdom, what it is and how it applies in both life and business - The dynamics of looking beyond profit and creating value - Change, its inevitability and how to manage change while retaining stability - The importance and power of values, virtue and purpose in organizations - Business values and their importance in creating growth-focused and profitable organisations
Author: Farid Rahimi
Publisher: Springer Science & Business Media
ISBN: 9400727739
Category : Medical
Languages : en
Pages : 568
Get Book Here
Book Description
Amyloid-forming proteins are implicated in over 30 human diseases. The proteins involved in each disease have unrelated sequences and dissimilar native structures, but they all undergo conformational alterations to form fibrillar polymers. The fibrillar assemblies accumulate progressively into disease-specific lesions in vivo. Substantial evidence suggests these lesions are the end state of aberrant protein folding whereas the actual disease-causing culprits likely are soluble, non-fibrillar assemblies preceding the aggregates. The non-fibrillar protein assemblies range from small, low-order oligomers to spherical, annular, and protofibrillar species. Oligomeric species are believed to mediate various pathogenic mechanisms that lead to cellular dysfunction, cytotoxicity, and cell loss, eventuating in disease-specific degeneration and systemic morbidity. The particular pathologies thus are determined by the afflicted cell types, organs, systems, and the proteins involved. Evidence suggests that the oligomeric species may share structural features and possibly common mechanisms of action. In many cases, the structure–function interrelationships amongst the various protein assemblies described in vitro are still elusive. Deciphering these intricate structure–function correlations will help understanding a complex array of pathogenic mechanisms, some of which may be common across different diseases albeit affecting different cell types and systems.
Author: Srushti Panchal
Publisher: Verses Kindler Publication
ISBN:
Category : Fiction
Languages : en
Pages :
Get Book Here
Book Description
A collection of work by 25 writers, who wish to intrigue you into unshackling your thoughts from the metaphorical chain that restricts them. This anthology brings forth our tendency to bind our thoughts and actions in society's chains and moulding ourselves in the way it dictates. All the Co- authors in the book have put into perspective the NORMS WE HAVE NORMALISED. The thoughts brought out in this book often remain hidden and subdued within the unreachable corners of our thoughtful minds. So Unshackle is just a small effort to put pen, paper and mind in use to inspire everyone to break away from what unnecessarily restricts us. It is all in our mind and actions.
Author: Elsevier Clinics
Publisher: Elsevier Health Sciences
ISBN: 0323655149
Category : Medical
Languages : en
Pages :
Get Book Here
Book Description
This volume of Orthopedic Clinics will focus on Surgical Considerations for Osteoporosis, Osteopenia, and Vitamin D Deficiency. Edited by members of a distinguished editorial board from the Campbell Clinic. Each issue features articles from the key subspecialty areas of knee and hip, hand and wrist, shoulder and elbow, foot and ankle, pediatrics, and trauma. Topics discussed in the issue will include, but are not limited to: The Role of Vitamin D in Pediatric Orthopedics, Pediatric Orthopaedic Aspects of Osteogenesis Imperfecta (OI), Surgical considerations in the treatment of osteoporotic proximal humerus fractures, Surgical considerations in managing poor bone quality during arthroscopic rotator cuff repair, Surgical Considerations for Osteoporosis in Foot & Ankle surgery, and Surgical Considerations for Vitamin D Deficiency in Foot & Ankle surgery.
Author:
Publisher: Elsevier
ISBN: 0444639535
Category : Medical
Languages : en
Pages : 520
Get Book Here
Book Description
Human Prion Diseases, Volume 153 is designed to update the reader on the latest advances and clinical aspects of prion diseases. The book is organized into five sections, including the pathophysiology of prions and a description of animal and human diseases. This is followed by detailed reports on recent advances in diagnosis strategies for the development of novel anti-prion molecules and possible designs of clinical trials in such a rare disease. An introductory chapter gives an extensive historical background of prion research, with a final chapter highlighting recent progress, and more importantly, unsolved problems. - Offers an authoritative overview of prion diseases in humans, detailing the pathogenesis of the disease, clinical investigations, and the diagnosis of both the genetic and acquired forms - Provides clarity and context by presenting prion diseases in relation to other neurodegenerative diseases in humans - Emphasizes the unique properties of prion diseases and consequent problems they can cause, both clinically and in public health terms
Author: Panos Liatsis
Publisher: Springer Nature
ISBN: 3030972550
Category : Computers
Languages : en
Pages : 391
Get Book Here
Book Description
This volume constitutes selected papers presented at the First International Conference on Emerging Technology Trends in IoT and Computing, TIOTC 2021, held in Erbil, Iraq, in June 2021. The 26 full papers were thoroughly reviewed and selected from 182 submissions. The papers are organized in the following topical sections: Internet of Things (IOT): services and applications; Internet of Things (IOT) in healthcare industry; IOT in networks, communications and distributed computing; real world application fields in information science and technology.
